Cross-sectional study of blood biomarkers of patients with moderate to severe alopecia areata reveals systemic immune and cardiovascular biomarker dysregulation.

abstract：:Lipoid proteinosis (Urbach-Wiethe disease) is a rare, recessively inherited disorder that is characterized by the deposition of hyaline-like material in the skin, oral cavity, and other tissues. It usually appears in infancy with hoarseness. We report a case of lipoid proteinosis in a 10-year-old boy that demonstrates...

journal_title：Journal of the American Academy of Dermatology

authors： Konstantinov K,Kabakchiev P,Karchev T,Kobayasi T,Ullman S

更新日期：1992-08-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor usually involving soft tissue and, in rare cases, the skin. Histologically and biologically it is considered to be a borderline neoplasm between an angiolymphoid hyperplasia with eosinophilia and an epithelioid angiosarcoma. Here we describe an 1...

journal_title：Journal of the American Academy of Dermatology

authors： Forschner A,Harms D,Metzler G,Sönnichsen K,Ulmer A,Rassner G,Fierlbeck G

更新日期：2003-07-01 00:00:00

abstract：:Cutaneous metastases present themselves in a variety of clinical patterns and tend to be manifested as indurated papules/nodules/tumors. Some of those clinical expressions are unique for certain types of metastases. This report describes an entirely different phenomenon of clinically incognito cutaneous metastases tha...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,DiLeonardo M,Gibbons G

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：:We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bon...

journal_title：Journal of the American Academy of Dermatology

authors： Welsh O,Sauceda E,Gonzalez J,Ocampo J

更新日期：1987-09-01 00:00:00

abstract：:A 7-week-old male infant with a seizure disorder and an extensive sebaceous nevus of the scalp was examined. Computerized axial tomography (CAT) scan identified an intracerebral mass which proved to be a hamartomatous malofrmation fo the brain. The association of intracranial masses with sebaceous nevi should be recog...

journal_title：Journal of the American Academy of Dermatology

authors： Moskowitz R,Honig PJ

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Little is known about how individuals with a predisposition for rosacea appear in childhood. This retrospective, matched control, longitudinal study examined the relationship between childhood stye and adult rosacea. METHODS:The records of the Rochester Epidemiology Project were examined to identify patient...

journal_title：Journal of the American Academy of Dermatology

authors： Bamford JT,Gessert CE,Renier CM,Jackson MM,Laabs SB,Dahl MV,Rogers RS 3rd

更新日期：2006-12-01 00:00:00

abstract：:Recent advances in our basic understanding of immunology, specifically the roles of various cell types involved in immune response and the action of cytokines they produce, has radically changed our understanding of the origin of inflammatory dermatoses, and other autoimmune diseases. Broadened comprehension of the im...

journal_title：Journal of the American Academy of Dermatology

authors： Nickoloff BJ,Stevens SR

更新日期：2006-03-01 00:00:00

abstract：:A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nife...

journal_title：Journal of the American Academy of Dermatology

authors： Fairley JA,Pentland AP,Voorhees JJ

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Although cutaneous Crohn's disease is well recognized in adults, in children it is extremely rare. OBJECTIVE:Our purpose was to describe five children with cutaneous Crohn's disease and to review the literature. METHODS:The medical records of five children with cutaneous Crohn's disease were retrospectivel...

journal_title：Journal of the American Academy of Dermatology

authors： Ploysangam T,Heubi JE,Eisen D,Balistreri WF,Lucky AW

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Brachioradial pruritus (BRP) is a localized pruritus of the dorsolateral aspect of the arm. BRP is an enigmatic condition with a controversial cause; some authors consider BRP to be a photodermatosis whereas other authors attribute BRP to compression of cervical nerve roots. OBJECTIVE:We sought to investiga...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen AD,Masalha R,Medvedovsky E,Vardy DA

更新日期：2003-06-01 00:00:00

abstract：:Ticks are ectoparasites that cause dermatologic disease directly by their bite and indirectly as vectors of bacterial, rickettsial, protozoal, and viral diseases. In North America, where ticks are the leading cause of vector-borne infection, dermatologists should recognize several tick species. Basic tick biology and ...

journal_title：Journal of the American Academy of Dermatology

authors： McGinley-Smith DE,Tsao SS

更新日期：2003-09-01 00:00:00

abstract：:Reflections from instruments in the surgical field involving the CO2 laser beam present a serious ocular hazard. In addition to the use of plastic or glass protective eyewear, this hazard can be minimized by utilizing anodized instruments and recognizing the specific distances at which various reflections are no longe...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman NR,Saleeby ER,Rubin MG,Sandu T,Krull EA

更新日期：1987-11-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：:A 38-year-old woman came for treatment of multiple clear vesicles and hemorrhagic papules on the posterior aspect of the right shoulder and the right axillary vault of 5 years' duration. These lesions would spontaneously manifest as clear or blood-filled vesicles (or both) and appear to be exacerbated by physical cont...

journal_title：Journal of the American Academy of Dermatology

authors： Bikowski JB,Dumont AM

更新日期：2005-09-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：:Phototherapy is a mainstay in the treatment of psoriasis and is available as psoralen plus UVA (PUVA), broadband UVB (BB-UVB), and narrowband UVB (NB-UVB). Phototherapy can be administered in the hospital, outpatient clinic, or in the patient's home. The purpose of this review is to provide some practical guidance to ...

journal_title：Journal of the American Academy of Dermatology

authors： Lapolla W,Yentzer BA,Bagel J,Halvorson CR,Feldman SR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:A discrimination between benign and malignant melanocytic lesions is not always possible by conventional histology. OBJECTIVE:Our purpose was to determine the proliferative activity in various types of melanocytic neoplasms and to appraise its value as a diagnostic adjunct. METHODS:The growth fraction was ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph P,Schubert C,Schubert B,Parwaresch R

更新日期：1997-08-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:We reviewed all cases of malignant melanoma in children younger than 17 years of age who were evaluated at Sainte Justine Hospital, a tertiary care pediatric center, between 1980 and 2002. The medical records and histologic features of all cases were reviewed. Thirteen cases were identified, 4 boys and 9 girls. Fifty-...

journal_title：Journal of the American Academy of Dermatology

authors： Jafarian F,Powell J,Kokta V,Champagne M,Hatami A,McCuaig C,Marcoux D,Savard P

更新日期：2005-11-01 00:00:00

abstract：:The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bernal JE,Duran de Rueda MM,Ordonez CP,Duran C,de Brigard D

更新日期：1990-06-01 00:00:00

abstract：:Vitiligo is a common autoimmune disease that progressively destroys melanocytes in the skin, resulting in the appearance of patchy depigmentation. This disfiguring condition frequently affects the face and other visible areas of the body, which can be psychologically devastating. The onset of vitiligo often occurs in ...

journal_title：Journal of the American Academy of Dermatology

authors： Rodrigues M,Ezzedine K,Hamzavi I,Pandya AG,Harris JE,Vitiligo Working Group.

更新日期：2017-07-01 00:00:00

abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz BC,Roenigk HH Jr

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Few data exist on the relationship between psoriasis and melanocytic lesions. OBJECTIVES:We sought to investigate number of melanocytic nevi in psoriatic patients compared with control subjects and its relationship with disease severity and treatment. METHODS:We performed a prospective study in 189 psoriat...

journal_title：Journal of the American Academy of Dermatology

authors： Di Cesare A,Riitano A,Suppa M,Fidanza R,Zangrilli A,Esposito M,Fargnoli MC,Chimenti S,Peris K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：:A large variety of underlying conditions and diseases have been associated with zygomycosis. The most common ones include leukemia or lymphoma, burns, renal failure, septicemia, malnutrition, diabetes, cancer, chemotherapy, organ transplantation, and corticosteroid administration. While being ubiquitous in the environ...

journal_title：Journal of the American Academy of Dermatology

authors： Bateman CP,Umland ET,Becker LE

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF), the most common form of cutaneous T-cell lymphoma, typically presents in middle-aged to elderly individuals. OBJECTIVE:We sought to study the demographics, clinicopathologic features, treatment response, and prognosis of patients with biopsy-proven MF diagnosed before 20 years of age...

journal_title：Journal of the American Academy of Dermatology

authors： Boulos S,Vaid R,Aladily TN,Ivan DS,Talpur R,Duvic M

更新日期：2014-12-01 00:00:00

abstract：:Onycholysis (ONY) of the fingernails is a common disorder that is diagnosed with ease but often managed with great difficulty. The full spectrum of causes is broad and not always readily apparent. In this review, an approach to the evaluation and management of ONY is offered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kechijian P

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. OBJECTIVE:We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discont...

journal_title：Journal of the American Academy of Dermatology

authors： Piaserico S,Cazzaniga S,Chimenti S,Giannetti A,Maccarone M,Picardo M,Peserico A,Naldi L,Psocare Study Group.

更新日期：2014-02-01 00:00:00

abstract：:The common blue nevus is a benign, localized collection of dermal melanocytes. To date, removal required excisional surgery to eliminate pigment that usually extends into the reticular dermis. We report the successful long-term elimination of common blue nevi on the nasal skin of two patients whose lesions were treate...

journal_title：Journal of the American Academy of Dermatology

authors： Milgraum SS,Cohen ME,Auletta MJ

更新日期：1995-02-01 00:00:00