Abstract：
:We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bone were involved. We evaluated the results by clinical, radiologic, and laboratory tests. No important side effects were detected during or after the therapy.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Welsh O,Sauceda E,Gonzalez J,Ocampo Jdoi
10.1016/s0190-9622(87)70227-8subject
Has Abstractpub_date
1987-09-01 00:00:00pages
443-8issue
3eissn
0190-9622issn
1097-6787pii
S0190-9622(87)70227-8journal_volume
17pub_type
临床试验,杂志文章abstract：:Isotretinoin has demonstrated efficacy in a wide range of disorders. The beneficial effects of the drug, however, are limited by its adverse effects on the bone. Children exposed to high doses are at risk for premature epiphyseal closure, while adults on long-term therapy have an increased tendency to develop hypersto...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1067/mjd.2001.113721
更新日期：2001-11-01 00:00:00
abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(89)70094-3
更新日期：1989-05-01 00:00:00
abstract：:Certain scalp hair shafts from 2 of 10 cases of pili annulati examined by scanning electron microscopy exhibited an unusual weathering pattern. The majority of affected hair shafts showed minor surface abnormalities at regular intervals (nodes) associated with the underlying spaces. However, in a few examples, there w...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1067/mjd.2001.114748
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge. METHODS:We report a case using an enzyme-linked immunosorbent assay (ELISA) test. RESULTS:A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identif...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2006.04.065
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:Dermatopathologists often are asked by clinicians to report margins on punch excisions of melanocytic lesions. OBJECTIVE:We sought to determine the adequacy of surgical margins on melanocytic lesions submitted with intention of complete excision using punch removal technique. METHODS:We conducted prospecti...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2008.09.037
更新日期：2009-06-01 00:00:00
abstract：:Superantigens (SAgs) are virulent polypeptides that are produced by a variety of infectious organisms. They are capable of causing nonspecific T cell activation by circumventing normal antigen processing in the human host. The genetic makeup of the host plays a role in conferring susceptibility or protection against S...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2010.03.044
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:It is important for dermatologists and other physicians in refugee-receiving countries to acquire knowledge of forensic dermatology to identify lesions from torture. OBJECTIVE:Review forensic dermatology in cases of torture. RESULTS:In providing medical assessment and care to refugees and migrants, chronic...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2020.09.031
更新日期：2020-09-15 00:00:00
abstract：BACKGROUND:The negative pigment network (NPN) is seen as a negative of the pigmented network and it is purported to be a melanoma-specific structure. OBJECTIVES:We sought to assess the frequency, sensitivity, specificity, and odds ratios (ORs) of NPN between melanoma cases and a group of control lesions. METHODS:Digi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2012.08.012
更新日期：2013-04-01 00:00:00
abstract：:Nail-patella syndrome (NPS) is an autosomal dominant genetic defect, which may be associated with, or closely linked to, the locus controlling palmar and plantar hyperhidrosis (HH). A clinical review of a family with NPS involving six generations was performed. Data were accumulated by personal examination and analysi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(80)80079-x
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:Some hereditary palmoplantar keratodermas (PPK) have been defined at the molecular level. OBJECTIVE:Our purpose was to establish the cause of a hereditary PPK with unique histopathologic findings in the epidermis. METHODS:Investigative studies included light and electron microscopy and determination of gen...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(97)70208-1
更新日期：1997-07-01 00:00:00
abstract：BACKGROUND:The association of human herpesvirus 6 (HHV-6) and HHV-7 with pityriasis rosea suggests that systemic drugs directed against HHV may hasten recovery of patients with pityriasis rosea. OBJECTIVE:The purpose of this study was to verify the efficacy of oral acyclovir in the treatment of pityriasis rosea. METH...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2005.06.042
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2014.01.907
更新日期：2014-08-01 00:00:00
abstract：:Kaposi's sarcoma in American blacks is relatively rare, according to the literature. Using information from the Tumor Registry of Charity Hospital of Louisiana in New Orleans, we discuss the available data on nineteen black patients (10 men, 9 women), with histologically diagnosed Kaposi's sarcoma between the years 19...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(84)70206-4
更新日期：1984-10-01 00:00:00
abstract：:We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case th...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(89)70336-4
更新日期：1989-12-01 00:00:00
abstract：:Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic diso...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(83)70113-1
更新日期：1983-07-01 00:00:00
abstract：:The clinical, electron microscopic, and freeze-fracture features of the skin of a harlequin fetus are described. Ultrastructural findings included large, concentric lamellar bodies, focal absence of intercellular stratum corneum lipid, and an increase in the size of desmosomes and the number of tight junctions. Althou...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(89)70289-9
更新日期：1989-11-01 00:00:00
abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(87)70011-5
更新日期：1987-01-01 00:00:00
abstract：:Betel is a compound of natural substances chewed for its psychostimulating effects. Betel is composed of the nut of the areca palm (Areca catechu), the leaf of the betel pepper (Piper betle), and lime (calcium hydroxide). Approximately 200 million persons chew betel regularly throughout the western Pacific basin and s...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(98)70543-2
更新日期：1998-01-01 00:00:00
abstract：:The sudden eruption of atypical and benign melanocytic nevi has been associated with a number of disease states and primary skin conditions. Most case reports and series of patients have linked eruptive nevi with blistering skin disease or immunosuppression. Subsets of patients in the immunosuppressed category have re...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2004.08.009
更新日期：2005-05-01 00:00:00
abstract：BACKGROUND:Photosensitivity (PS) in lupus erythematosus (LE) is frequently determined by patient report. OBJECTIVE:We sought to characterize self-reported PS in cutaneous LE (CLE). METHODS:The PS survey was used to classify subject responses into 5 phenotypes: direct sun-induced CLE flare (directCLE); general exacerb...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2013.03.015
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a recurrent hemorrhagic papular skin eruption with a clinically benign course and histopathologic features of lymphoma. OBJECTIVE AND METHODS:To better characterize this disease, we studied 53 patients seen since 1965. RESULTS:A lymphoproliferative malignancy developed withi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(94)70019-2
更新日期：1994-02-01 00:00:00
abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(99)70375-0
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Single-institution studies show that frozen section Mohs micrographic surgery (MMS) is an effective treatment modality for cutaneous melanoma, but no multi-institutional studies have been published. OBJECTIVE:To characterize the use of MMS in the treatment of melanoma at 3 academic and 8 private practices t...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jaad.2019.05.057
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Lipedematous alopecia and lipedematous scalp are two similar unusual conditions mostly affecting healthy black women. OBJECTIVE:The purpose of our study was to report three cases of this condition with emphasis on clinical and histologic findings, and to review the literature on the subject. METHODS:The st...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2004.05.016
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Flushing and erythema are frequent skin symptoms in rosacea. Because their adequate treatment remains a clinical challenge, new treatment options are explored, such as oral β-blockers. OBJECTIVES:To evaluate the efficacy of oral β-blockers for rosacea-associated facial flushing and erythema. METHODS:PubMed...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2020.04.129
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:The Nikolskiy sign is a well-known mechanical symptom that can be helpful in the diagnosis of pemphigus. The reports about associations with other than pemphigus cause confusion concerning the diagnostic importance of the Nikolskiy sign in pemphigus. OBJECTIVE:Our purpose was to examine the significance and...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2005.10.019
更新日期：2006-03-01 00:00:00
abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2010.02.062
更新日期：2010-12-01 00:00:00
abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(91)70284-9
更新日期：1991-11-01 00:00:00
abstract：:Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2012.05.036
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Pneumocystis carinii pneumonia (PCP) causes morbidity and mortality in immunocompromised hosts. Data describing use of PCP prophylaxis in immunosuppressed dermatologic patients are lacking. OBJECTIVE:We sought to describe the frequency of PCP among dermatologic patients receiving immunosuppression for immun...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2009.07.042
更新日期：2010-06-01 00:00:00
