Harlequin ichthyosis: an ultrastructural study.

abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

journal_title：Journal of the American Academy of Dermatology

authors： Jewell ML,McCauliffe DP

更新日期：2000-06-01 00:00:00

abstract：:Polymorphous sweat gland carcinoma is an unusual, recently described variant of low-grade malignant adnexal neoplasm of the skin characterized by a prolonged clinical course and predilection for the extremities. We describe a case of recurrent polymorphous sweat gland carcinoma in a 56-year-old man who presented with ...

journal_title：Journal of the American Academy of Dermatology

authors： Ronnen M,Ben-Dor D,Huszar M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Although etanercept is used as a continuous therapy for moderate to severe plaque psoriasis, intermittent use may be necessary in some instances. OBJECTIVE:In this randomized, open-label study, we evaluated the effectiveness and safety of continuous versus interrupted etanercept therapy. METHODS:All patien...

journal_title：Journal of the American Academy of Dermatology

authors： Moore A,Gordon KB,Kang S,Gottlieb A,Freundlich B,Xia HA,Stevens SR

更新日期：2007-04-01 00:00:00

abstract：:We describe a patient with clinical features of dermatitis herpetiformis (DH) and histopathologic features suggestive of both DH and bullous pemphigoid (BP). Immunofluorescent (IF) studies of skin biopsy revealed IgG and C3 deposits along the basement membrane zone (BMZ) in a linear pattern and circulating BMZ antibod...

journal_title：Journal of the American Academy of Dermatology

authors： Jawitz J,Kumar V,Nigra TP,Beutner EH

更新日期：1984-05-01 00:00:00

abstract：:Multiple modalities exist for the treatment of keratoacanthoma. Excisional surgery is currently the treatment of choice for the majority of keratoacanthomas. This can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable...

journal_title：Journal of the American Academy of Dermatology

authors： Melton JL,Nelson BR,Stough DB,Brown MD,Swanson NA,Johnson TM

更新日期：1991-12-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:There are subgroups of cutaneous squamous cell carcinoma (SCC) that have a higher risk for both regional and distant metastasis. When cutaneous SCC does metastasize, it typically spreads first to local nodal groups. Sentinel lymph node (SLN) localization has been successfully used to evaluate nodal metastasi...

journal_title：Journal of the American Academy of Dermatology

authors： Weisberg NK,Bertagnolli MM,Becker DS

更新日期：2000-09-01 00:00:00

abstract：:Clinical examination is critical for the diagnosis and identification of response to treatment. It is fortunate that technologies are continuing to evolve, enabling augmentation of classical clinical examination with noninvasive imaging modalities. This article discusses emerging technologies with a focus on digital p...

journal_title：Journal of the American Academy of Dermatology

authors： Schneider SL,Kohli I,Hamzavi IH,Council ML,Rossi AM,Ozog DM

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Carney complex (CNC) is an autosomal dominant disorder associated with multiple neoplasms. OBJECTIVE:We report a case of a 40-year-old Caucasian man with a sporadic form of CNC. METHODS:This is a clinicopathologic description and molecular biological study with an emphasis on histopathologic findings. RES...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Sima R,Michal M,Hes O,Roucka P,Zarybnicka M,Hora M,Chudacek Z,Kazakov DV

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Antibodies against transcriptional intermediary factor (TIF)-1γ are associated with malignancy in dermatomyositis (DM). Identification of clinical findings associated with anti-TIF-1γ antibodies in DM is a high priority for both patient diagnosis and risk assessment. OBJECTIVE:We sought to define the clinic...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino DF,Kuo K,Chung L,Zaba L,Li S,Casciola-Rosen L

更新日期：2015-03-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Phototherapy may be effective in atopic dermatitis (AD). Medium-dose (MD) ultraviolet (UV) A1 was introduced for the treatment of AD. Few immunohistochemical data are available pertaining to phototherapy in AD. Regulatory T cells may play a role in clearing AD. OBJECTIVES:We sought to compare the clinical a...

journal_title：Journal of the American Academy of Dermatology

authors： Majoie IM,Oldhoff JM,van Weelden H,Laaper-Ertmann M,Bousema MT,Sigurdsson V,Knol EF,Bruijnzeel-Koomen CA,de Bruin-Weller MS

更新日期：2009-01-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:As a wider variety of organisms are being identified in superficial fungal infections, more accurate methods of identification may be required to determine fungal susceptibility. The sensitivity of available methods, such as the minimal inhibitory concentration test, is reviewed. The sensitivities of causative pathoge...

journal_title：Journal of the American Academy of Dermatology

authors： Meinhof W

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:In animal models, extracts from green tea have been shown to be remarkably effective at reducing the severity of adverse human health effects of overexposure to ultraviolet (UV) radiation. Although sunscreens and other photoprotective measures have traditionally been used for this purpose, there is a need fo...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA,Singh D,Tubesing K,Matsui M,Katiyar S,Mukhtar H

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:It is generally believed that dihydrotestosterone is one of the pivotal mediators of hair loss in androgenetic alopecia (AGA). Finasteride, which blocks the conversion of testosterone to dihydrotestosterone, has now become an integral part of the current treatment approaches for male AGA. Several lines of ev...

journal_title：Journal of the American Academy of Dermatology

authors： Tang L,Bernardo O,Bolduc C,Lui H,Madani S,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：:Scleromyxedema is a rare fibromucinous connective tissue that can be associated with systemic changes, such as myopathy, neurologic defects, esophageal dysmotility, paraproteinemia, and restrictive lung disease. We describe a fatal case of scleromyxedema in which neurologic, cardiac, gastrointestinal, and muscle chang...

journal_title：Journal of the American Academy of Dermatology

authors： Godby A,Bergstresser PR,Chaker B,Pandya AG

更新日期：1998-02-01 00:00:00

abstract：:A persistent periocular dermatitis resulting from the prolonged use of topical fluorinated corticosteroids that resembled the perioral variety was observed in three patients. All topical therapy was ineffective until systemic tetracycline was administered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher AA

更新日期：1986-10-01 00:00:00

abstract：:A case of porphyria cutanea tarda in a human immunodeficiency virus-infected patient with hemophilia is reported. Onset of skin manifestations of porphyria cutanea tarda coincided with deterioration of immune function. However, acquired immunodeficiency syndrome has not yet developed with a follow-up interval of 39 mo...

journal_title：Journal of the American Academy of Dermatology

authors： Conlan MG,Hoots WK

更新日期：1992-05-01 00:00:00

abstract：:The analysis of population-specific human leukocyte antigen (HLA) haplotypes has provided evidence that susceptibility to psoriasis is linked to the class I and II major histo-compatibility complex on human chromosome 6. In addition, these studies show that psoriasis consists of two distinct disease subtypes (type I a...

journal_title：Journal of the American Academy of Dermatology

authors： Henseler T

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Photodynamic therapy (PDT) and imiquimod are the treatments of choice for actinic keratosis (AK). As they have different mechanisms of action, it seems reasonable to assume that applying both treatments sequentially would be efficacious. OBJECTIVES:We sought to determine which of these therapeutic modalitie...

journal_title：Journal of the American Academy of Dermatology

authors： Serra-Guillén C,Nagore E,Hueso L,Traves V,Messeguer F,Sanmartín O,Llombart B,Requena C,Botella-Estrada R,Guillén C

更新日期：2012-04-01 00:00:00

abstract：:Three clinicopathologic variants of lichen planopilaris are described. The first is characterized clinically by individual keratotic follicular papules and histologically by a lichenoid inflammatory cell infiltrate confined to the follicular epithelium. The second variant consists of erythematous to violaceous plaques...

journal_title：Journal of the American Academy of Dermatology

authors： Matta M,Kibbi AG,Khattar J,Salman SM,Zaynoun ST

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:There is limited data on zoster recurrence. OBJECTIVE:To examine in detail zoster recurrence in a population-based cohort. METHODS:Using data from a large cohort (The 45 and Up Study) with linked medical data (2004-2015), the incidence of first and recurrent zoster was examined using survival analyses meth...

journal_title：Journal of the American Academy of Dermatology

authors： Qian J,Macartney K,Heywood AE,Sheridan S,Liu B

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：:Pruritus is a common and often times difficult to treat symptom in many dermatologic and systemic diseases. For pruritus with an inflammatory or autoimmune origin, therapies such as topical corticosteroids and antihistamines are often initiated. However, in the case that these and additional systemic therapies are ine...

journal_title：Journal of the American Academy of Dermatology

authors： Sharma D,Kwatra SG

更新日期：2016-02-01 00:00:00

abstract：:More than 1100 patients were tested with methylchloroisothiazolinone-methylisothiazolinone, 100 ppm, in aqueous and petrolatum-based patch test materials from 1985 to 1987 by members of the North American Contact Dermatitis Group. Thirteen reactions to the aqueous materials and 10 to the petrolatum-based materials wer...

journal_title：Journal of the American Academy of Dermatology

authors： Rietschel RL,Nethercott JR,Emmett EA,Maibach HI,Storrs FJ,Larsen WG,Adams RM,Taylor JS,Marks JG Jr,Mitchell JC

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) has traditionally focused on minimizing recurrence and complication rates. However, the assessment of patient satisfaction and quality of life (QOL) is also important. These outcomes are best assessed by patient-reported outcome (PRO) ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee EH,Klassen AF,Nehal KS,Cano SJ,Waters J,Pusic AL

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The cause of rosacea is unknown; among other factors a causative role has been postulated for the hair follicle mites Demodex folliculorum and Demodex brevis. OBJECTIVE:Our purpose was to compare the population density of Demodex mites in facial skin of defined categories of patients with rosacea with contr...

journal_title：Journal of the American Academy of Dermatology

authors： Bonnar E,Eustace P,Powell FC

更新日期：1993-03-01 00:00:00

abstract：:Digital squamous cell carcinoma (SCC) presents a diagnostic challenge because of its relatively rare occurrence and mimicry of benign conditions. Although low-risk human papillomavirus (HPV) subtypes are commonly associated with benign digital verrucae, digital SCC can be associated with high-risk, oncogenic HPV subty...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Groft CM,Miller CJ,Kovarik CL

更新日期：2011-05-01 00:00:00

abstract：:Several infections contracted in utero result in similar physical and laboratory findings during the neonatal period; the TORCH syndrome encompasses such patients. Skin lesions are a frequent finding and the dermatologist may play an important role in the early evaluation of these infants. In this review we discuss et...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Arndt KA

更新日期：1985-04-01 00:00:00