Periocular dermatitis akin to the perioral variety.

abstract：:Bullous lesions associated with non-01 Vibrio cholerae developed in a patient with hepatic cirrhosis who had recently ingested raw oysters. He died of overwhelming sepsis despite 5 days of aggressive antibiotic therapy. Non-01 V. cholerae was isolated from blood, peritoneal fluid, and bullae. The organism produced a c...

journal_title：Journal of the American Academy of Dermatology

authors： Newman C,Shepherd M,Woodard MD,Chopra AK,Tyring SK

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The epidemiology of pediatric melanoma is distinct from that seen in adults. This is more distinguishable when pediatric patients are separated into prepubertal and adolescent groups. OBJECTIVE:In this study, we compared epidemiologic, clinical, histologic, and molecular characteristics of pediatric superfi...

journal_title：Journal of the American Academy of Dermatology

authors： Verzì AE,Bubley JA,Haugh AM,Zhang B,Wagner A,Kruse L,West DP,Wayne J,Guitart J,Gerami P

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Although hypersensitivity reactions are well characterized for certain medications, vancomycin-associated drug-induced hypersensitivity syndrome (DIHS), or drug reaction with eosinophilia and systemic symptoms (DRESS), has yet to be defined. OBJECTIVE:To better define the clinical phenotype of vancomycin-as...

journal_title：Journal of the American Academy of Dermatology

authors： Madigan LM,Fox LP

更新日期：2019-07-01 00:00:00

abstract：:Isotretinoin has demonstrated efficacy in a wide range of disorders. The beneficial effects of the drug, however, are limited by its adverse effects on the bone. Children exposed to high doses are at risk for premature epiphyseal closure, while adults on long-term therapy have an increased tendency to develop hypersto...

journal_title：Journal of the American Academy of Dermatology

authors： DiGiovanna JJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Onychomatricoma (OM) is a rare benign tumor of the nail matrix in which genome-wide analyses have never been performed. It is clinically characterized by an increased transversal curvature of the nail plate, a longitudinal yellowish discoloration, and splinter hemorrhages. Once the nail plate has been remove...

journal_title：Journal of the American Academy of Dermatology

authors： Cañueto J,Santos-Briz Á,García JL,Robledo C,Unamuno P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE). OBJECTIVE:We describe the clinical and histopathologic differences between the two diseases. METHODS:We reviewed clinical findings and histopathologic changes in two c...

journal_title：Journal of the American Academy of Dermatology

authors： Chun SI,Ji HG

更新日期：1992-12-01 00:00:00

abstract：:Fibrous harmartoma of infancy is a benign soft tissue tumor that occurs in the first few years of life. Although the lesion is not distinctive clinically, it has a characteristic microscopic appearance. Only 12 cases of fibrous hamartoma of infancy have been reported in the dermatology literature. ...

journal_title：Journal of the American Academy of Dermatology

authors： Scott DM,Peña JR,Omura EF

更新日期：1999-11-01 00:00:00

abstract：:Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. Phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm(2) and increased to a maximum of 1500 mJ/cm(2). All lesions disappeared completely aft...

journal_title：Journal of the American Academy of Dermatology

authors： Ohe S,Danno K,Sasaki H,Isei T,Okamoto H,Horio T

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:The eruptive appearance of numerous seborrheic keratoses, the sign of Leser-Trélat, has been regarded as a reliable cutaneous marker of internal malignancy. OBJECTIVE:We have evaluated the possible association of malignant disease and the sign in 1752 consecutive cases of seborrheic keratoses. METHODS:Firs...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Melander S

更新日期：1992-06-01 00:00:00

abstract：:We studied 20 Caucasian middle-aged patients, mostly women, who had asymptomatic, gray-brown patches with geographic borders, occasionally interspersed with hypopigmented macules, on the dorsum of the forearms, mostly bilaterally. The distal aspect of the arms was also involved in 2 patients; the face was always spare...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2000-04-01 00:00:00

abstract：:Ochronosis is an uncommon condition characterized by yellow-brown pigment deposits in the dermis. It occurs in exogenous and endogenous forms. We report a case of exogenous ochronosis in a Hispanic woman and discuss the different forms of this condition. We treated the lesions with Q-switched ruby laser. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kramer KE,Lopez A,Stefanato CM,Phillips TJ

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:The twin goals of long-term disease control and minimizing toxicities related to immunosuppression necessitate efforts to find effective steroid-sparing agents in the management of patients with autoimmune bullous diseases. Pemphigus especially requires a long view, because the disease can persist throughout...

journal_title：Journal of the American Academy of Dermatology

authors： McCarty M,Fivenson D

更新日期：2014-09-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:A series of thirty-eight cases of congenital nevocellular nevi were excised and studied histologically. Depending on the extent of nevoid cell dermal infiltration, four histologic patterns were observed: diffuse or patchy infiltration of the upper dermis alone, or diffuse or patchy infiltration of the upper and deep d...

journal_title：Journal of the American Academy of Dermatology

authors： Stenn KS,Arons M,Hurwitz S

更新日期：1983-09-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is an endogenous reactive oxygen species that contributes to oxidative stress directly as a molecular oxidant and indirectly through free radical generation. Topically applied 1% to 45% H2O2 can be used for a range of clinical purposes, which will be reviewed here in addition to its safety. In...

journal_title：Journal of the American Academy of Dermatology

authors： Murphy EC,Friedman AJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. OBJECTIVE:We sought to find out whether patients with AD had stinging, and to identify the pathocausal neuroimmune mechanisms, including the role of stress. METHODS:In all, 25 patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Lonne-Rahm S,Berg M,Mårin P,Nordlind K

更新日期：2004-12-01 00:00:00

abstract：:Tzaraat refers to a group of skin diseases that, according to the Old Testament, renders one ritually unclean. Analysis of the text reveals that there are four categories of lesions discussed. Each category has a primary lesion as well as specific secondary changes. The primary lesions include depigmented lesions on p...

journal_title：Journal of the American Academy of Dermatology

authors： Freilich AR

更新日期：1982-01-01 00:00:00

abstract：:Hyperkeratosis of the nipple and areola is a rare condition. We report two cases of hyperkeratosis of the nipple and areola occurring in men with no underlying endocrinopathy or synthetic estrogenic drug therapy. Both patients demonstrated prompt resolution of the hyperkeratosis of the nipples with a keratolytic gel. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhlman DS,Hodge SJ,Owen LG

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Relatively few persons with obsessive-compulsive disorder (OCD) come to psychiatric clinics for treatment. Our hypothesis was that patients with a form of OCD that involves compulsive hand and body washing might initially seek treatment from a dermatologist. OBJECTIVE:Our purpose was to screen patients atte...

journal_title：Journal of the American Academy of Dermatology

authors： Hatch ML,Paradis C,Friedman S,Popkin M,Shalita AR

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Symptomatic dermographism is the most common type of physical urticaria. It can be severe and poorly controlled with H1 antihistamines in some patients. Photochemotherapy (psoralen plus ultraviolet [UV] A) may help the itch of dermographism but the effect of narrowband (NB) UVB therapy has not been previousl...

journal_title：Journal of the American Academy of Dermatology

authors： Borzova E,Rutherford A,Konstantinou GN,Leslie KS,Grattan CE

更新日期：2008-11-01 00:00:00

abstract：:A 3-year-old boy presented two patches of light, bright, smooth, uncombable hair that were morphologically different from the rest of the hairs. Examination under scanning electron microscopy showed the morphologic characteristics of pili canaliculi and trianguli. Clinical and ultrastructural features seemed to corres...

journal_title：Journal of the American Academy of Dermatology

authors： Ravella A,Pujol RM,Noguera X,de Moragas JM

更新日期：1987-08-01 00:00:00

abstract：:It has previously been reported that interferon alfa injection sites may develop pyoderma gangrenosum, interface dermatitis, vasculitis, or, more commonly, ulcers characterized by intravascular thrombi and a mixed inflammatory cell infiltrate. We describe 2 patients in whom granulomatous and suppurative dermatitis dev...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders S,Busam K,Tahan SR,Johnson RA,Sachs D

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Seborrheic dermatitis is commonly treated with anti-inflammatory products, including topical corticosteroids. Pimecrolimus cream 1% also exerts anti-inflammatory activity by inhibiting T-cell cytokine production. OBJECTIVE:We sought to compare the efficacy and safety of twice-daily pimecrolimus for treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Wohlhuter RJ,Liu A,Zeller SA,Wenner RA,Bowers S,Schultz JC,Katz HI,McCormick CL,Parneix-Spake A

更新日期：2007-08-01 00:00:00

abstract：:Novel tretinoin cream and gel formulations have been developed that incorporate polyolprepolymer-2, which is a material designed to help retain drug molecules in and on the skin when applied in topical vehicles. The results of preclinical and clinical investigations have confirmed the beneficial impact of such a vehic...

journal_title：Journal of the American Academy of Dermatology

authors： Quigley JW,Bucks DA

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Epidermal necrolysis (EN) involving ≥10% of the body surface area (BSA) is often complicated by bacterial infections. OBJECTIVE:We sought to describe the epidemiology of bloodstream infections (BSIs) in EN involving a BSA ≥10% and the diagnostic performances of skin cultures for predicting the pathogen(s) i...

journal_title：Journal of the American Academy of Dermatology

authors： Lecadet A,Woerther PL,Hua C,Colin A,Gomart C,Decousser JW,Mekontso Dessap A,Wolkenstein P,Chosidow O,de Prost N,Ingen-Housz-Oro S

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Non-adherence rates are high among patients with psoriasis, partly because of discordance between recommended treatments and individual preferences. OBJECTIVES:Our aim was to assess the impact of comorbidities on patients' preferences for psoriasis treatments. METHODS:A computer-based conjoint analysis exp...

journal_title：Journal of the American Academy of Dermatology

authors： Schmieder A,Schaarschmidt ML,Umar N,Terris DD,Goebeler M,Goerdt S,Peitsch WK

更新日期：2012-09-01 00:00:00

abstract：:Pressure ulcers are localized areas of tissue necrosis that result from unrelieved pressure. They are graded or staged according to the degree of tissue damage observed. The main etiologic factors include pressure, shearing forces, friction, and moisture. The clinical course may be complicated by several conditions in...

journal_title：Journal of the American Academy of Dermatology

authors： Kanj LF,Wilking SV,Phillips TJ

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：:A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

journal_title：Journal of the American Academy of Dermatology

authors： De Villez RL

更新日期：1987-03-01 00:00:00