Treatment of keratoacanthomas with intralesional methotrexate.

abstract：BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

journal_title：Journal of the American Academy of Dermatology

authors： Stobaugh DJ,Deepak P,Ehrenpreis ED

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Some patients with pemphigus vulgaris (PV) have mucous membrane erosions with minimal skin involvement (mucosal dominant type), and others show extensive skin blisters and erosions in addition to mucous membrane involvement (mucocutaneous type). Patients with pemphigus foliaceus (PF) show only skin involveme...

journal_title：Journal of the American Academy of Dermatology

authors： Amagai M,Tsunoda K,Zillikens D,Nagai T,Nishikawa T

更新日期：1999-02-01 00:00:00

abstract：:Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin disease driven by keratinocyte hyperproliferation. During the next 20 years, the role of the immune system and T-helper (Th) cells in psori...

journal_title：Journal of the American Academy of Dermatology

authors： Lynde CW,Poulin Y,Vender R,Bourcier M,Khalil S

更新日期：2014-07-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：:Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...

journal_title：Journal of the American Academy of Dermatology

authors： Sajben FP,Gibbs NF,Friedlander SF

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：:A distinctive new hair condition, the loose anagen syndrome, features anagen hairs that are loosely anchored and easily pulled from the scalp. The children studied had sparse hair that did not grow long and that pulled easily from the scalp. The majority of patients were blond girls, aged 2 to 5 years, but both sexes ...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Gummer CL

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Exposure to ultraviolet radiation (from solar and nonsolar sources) is a risk factor for skin cancer. OBJECTIVE:We sought to summarize recent estimates on sunburns, sun-protection behaviors, and indoor tanning available from national and selected statewide behavioral surveys. METHODS:Estimates of the preva...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Cokkinides V,Hall HI,Hartman AM,Saraiya M,Miller E,Paddock L,Glanz K

更新日期：2011-11-01 00:00:00

abstract：:Skin cancer is the most common form of cancer in the United States and accounts for an estimated 1 million new cases per year. In the white population, the rate of new melanomas diagnosed yearly has more than doubled from 5/100,000 in 1973 to 12/100,000 in 1990. The current lifetime risks for white persons are estimat...

journal_title：Journal of the American Academy of Dermatology

authors： Pipitone M,Robinson JK,Camara C,Chittineni B,Fisher SG

更新日期：2002-07-01 00:00:00

abstract：:Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and...

journal_title：Journal of the American Academy of Dermatology

authors： Cotton J,Armstrong DJ,Wedig R,Hood AF

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

更新日期：2008-08-01 00:00:00

abstract：:Cannabis arteritis is a serious peripheral vascular disease affecting young adults consuming cannabis. An increasing number of cases have been recently reported in Europe. The risk of amputation is high. Cannabis arteritis is often confused with atherosclerosis. We present a new case in which complete arterial revascu...

journal_title：Journal of the American Academy of Dermatology

authors： Noël B,Ruf I,Panizzon RG

更新日期：2008-05-01 00:00:00

abstract：:Psychosomatic dermatology is practiced in some manner by every dermatologist. In spite of this, there has been a virtual void in the literature from the middle 1950s until the present time. The relationship to physiologic phenomena, as well as a classification of psychosomatic dermatology, is reviewed. Dermatologic pa...

journal_title：Journal of the American Academy of Dermatology

authors： Medansky RS,Handler RM

更新日期：1981-08-01 00:00:00

abstract：:Photodamaged skin occurs as a result of long-term exposure to ultraviolet radiation. The incidence of photodamage in European and North American populations with Fitzpatrick skin types I, II, and III is estimated at 80% to 90%. We conducted a double-blind clinical trial to test the efficacy and safety of 0.1% isotreti...

journal_title：Journal of the American Academy of Dermatology

authors： Maddin S,Lauharanta J,Agache P,Burrows L,Zultak M,Bulger L

更新日期：2000-01-01 00:00:00

abstract：:Lobular capillary hemangioma and bacillary angiomatosis due to Bartonella infection share several clinical and histopathologic characteristics. We sought to determine whether lobular capillary hemangioma is caused by the same agent as bacillary angiomatosis. Forty-five pathology specimens with a histologic diagnosis o...

journal_title：Journal of the American Academy of Dermatology

authors： Levy I,Rolain JM,Lepidi H,Raoult D,Feinmesser M,Lapidoth M,Ben-Amitai D

更新日期：2005-12-01 00:00:00

abstract：:Lymphocytoma cutis characteristically appears as persistent reddish purple papules, nodules, or plaques. Response to treatment is variable and recurrences are common. We report the use of the argon laser as a modality that improved cosmetic appearance and alleviated symptoms of lymphocytoma cutis but that failed to pr...

journal_title：Journal of the American Academy of Dermatology

authors： Wheeland RG,Kantor GR,Bailin PL,Bergfeld WF

更新日期：1986-02-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Warren R. Heymann, MD, are provided after each discussion as a topic summary and are provided here as a special service t...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2007-04-01 00:00:00

abstract：:Epidermolysis bullosa acquisita is a chronic, severe, subepidermal, blistering disease of the skin, characterized by marked resistance to topical and systemic therapy. This report concerns a well-documented case of a woman who had had epidermolysis bullosa acquisita for 6 years and had remained hospitalized continuous...

journal_title：Journal of the American Academy of Dermatology

authors： Crow LL,Finkle JP,Gammon WR,Woodley DT

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa simplex is a skin-blistering disorder caused by mutations in keratin (K)14 or K5. Treatment with nuclear factor (erythroid-derived 2)-like 2 inducer sulforaphane ameliorated skin blistering in Krt14-null mice, correlating with induction of K17. To be therapeutically useful for epidermol...

journal_title：Journal of the American Academy of Dermatology

authors： Kerns ML,Guss L,Fahey J,Cohen B,Hakim JM,Sung S,Lu RG,Coulombe PA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:We sought to determine what clinical features of psoriasis predict sleep interference. METHODS:Data were obtained from 420 respondents to the 2005 National Psoriasis Foundation telephone and e-mail surveys. Logistic regression was used to determine whether disease severity, body mass index, age of onset, pso...

journal_title：Journal of the American Academy of Dermatology

authors： Callis Duffin K,Wong B,Horn EJ,Krueger GG

更新日期：2009-04-01 00:00:00

abstract：:The advent of new topical agents such as topical calcineurin inhibitors, as well as the reformulations of older agents in new vehicles, has broadened the treatment approaches to psoriasis and atopic dermatitis. The clinician must now consider additional novel physiologic pathways and mechanisms of action as well as ex...

journal_title：Journal of the American Academy of Dermatology

authors： Norris DA

更新日期：2005-07-01 00:00:00

abstract：:Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...

journal_title：Journal of the American Academy of Dermatology

authors： Prado R,Ellis LZ,Gamble R,Funk T,Arbuckle HA,Bruckner AL

更新日期：2012-12-01 00:00:00

abstract：:Significant progress has been made in skin replacement options in the past several decades. Although initially various materials have been used mainly for burn coverage, their application to dermatologic practice has increased significantly. We review the research, progress, and other aspects of wound coverage with sy...

journal_title：Journal of the American Academy of Dermatology

authors： Límová M,Grekin RC

更新日期：1990-10-01 00:00:00

abstract：:Three cases of allergic contact hypersensitivity to Sta-Lok and Loctite anaerobic sealants are reported. These two anaerobic sealants constitute a +100 million annual market in industrial sealants used to join metal surfaces together. To the best of my knowledge, these are the first reported cases of allergic contact ...

journal_title：Journal of the American Academy of Dermatology

authors： Dempsey KJ

更新日期：1982-12-01 00:00:00

abstract：:A patient is described who developed sore throat, palpable purpura, and a distinctive panniculitis. The pathologic alterations in the subcutis were similar to what Wells described in the dermis as eosinophilic cellulitis. In our experience the presence of such a picture primarily in the subcutis is unique. Streptococc...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Burket BJ

更新日期：1985-01-01 00:00:00

abstract：:Myospherulosis is an uncommon subcutaneous disorder believed initially to be caused by an endosporulating fungus. Recently investigators have disproved an infectious cause and have shown that the disease represents an alteration in red blood cells, usually produced by petrolatum or lanolin, with an accompanying foreig...

journal_title：Journal of the American Academy of Dermatology

authors： Waldman JS,Barr RJ,Espinoza FP,Simmons GE

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Finasteride, a type II 5alpha-reductase inhibitor, reduces scalp and serum dihydrotestosterone and has been shown to be effective in men with androgenetic alopecia (AGA). OBJECTIVE:The purpose of this study was to determine the effect of finasteride on scalp hair weight in men with AGA. METHODS:Sixty-six m...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Menefee E,Sanchez M,Ruane P,Kaufman KD

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Established data confirm an increased incidence of skin cancer, mainly squamous cell carcinoma (SCC), in long-term kidney transplant recipients (KTRs). OBJECTIVE:Our purpose was to investigate prospectively the type and frequency of neoplastic and preneoplastic skin lesions in KTRs during the first 3 years ...

journal_title：Journal of the American Academy of Dermatology

authors： Ferrándiz C,Fuente MJ,Ribera M,Bielsa I,Fernández MT,Lauzurica R,Roca J

更新日期：1995-10-01 00:00:00

abstract：:The case of a 2-year-old Puerto Rican boy is presented. Clinical and histologic features are detailed because he showed peculiar jet black patches of pigmentation on the fingers of the right hand. This case, except for the lack of progression of the disease after a 2-year period of follow-up, shows many similarities t...

journal_title：Journal of the American Academy of Dermatology

authors： González JR,Vázquez Botet M

更新日期：1980-02-01 00:00:00