Lichen sclerosus.

abstract：BACKGROUND:Exposure to ultraviolet radiation (from solar and nonsolar sources) is a risk factor for skin cancer. OBJECTIVE:We sought to summarize recent estimates on sunburns, sun-protection behaviors, and indoor tanning available from national and selected statewide behavioral surveys. METHODS:Estimates of the preva...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Cokkinides V,Hall HI,Hartman AM,Saraiya M,Miller E,Paddock L,Glanz K

更新日期：2011-11-01 00:00:00

abstract：:A recent study demonstrated that hirsute women with irregular menses had higher levels of serum androgens that hirsute women with regular menses. To investigate this finding, we measured total testosterone, biologically active testosterone, free testosterone, androstenedione, dehydroepiandrosterone, and dehydroepiandr...

journal_title：Journal of the American Academy of Dermatology

authors： Salman K,Spielvogel RL,Miller JL,Rose LI

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:In recent years, increasing emphasis has been placed on value-based health care delivery. Dermatology must develop performance measures to judge the quality of services provided. The implementation of a national complication registry is one such method of tracking surgical outcomes and monitoring the safety ...

journal_title：Journal of the American Academy of Dermatology

authors： Council ML,Alam M,Gloster HM Jr,Bordeaux JS,Carroll BT,Leitenberger JJ,Wisco OJ,Maher IA

更新日期：2016-04-01 00:00:00

abstract：:A case of Staphylococcus aureus--induced bullous dermatosis limited to the sites of glucocorticosteroid-induced striae atrophicae is described. Skin with compromised mechanical integrity may be more susceptible to disruption by invasion of bacteria and/or by their exotoxin. The pathogenesis of striae atrophicae and th...

journal_title：Journal of the American Academy of Dermatology

authors： Bronstein SW,Bickers DR,Lamkin BC

更新日期：1984-02-01 00:00:00

abstract：:The occurrence of Kaposi's sarcoma in young homosexual men is a recently reported condition. The same individuals are at risk for the development of Pneumocystis carinii pneumonia and other unusual infections. These associations suggest these persons are somehow immunocompromised. Evidence of current or prior cytomega...

journal_title：Journal of the American Academy of Dermatology

authors： Rasmussen EO,Cooper KD,Kang K,White CR Jr,Regan DH,Hanifin JM

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

journal_title：Journal of the American Academy of Dermatology

authors： Jewell ML,McCauliffe DP

更新日期：2000-06-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：:This is the second reported case of minocycline-induced Sweet's syndrome (and the first such case to appear in the American literature). The syndrome developed in a 32-year-old man 10 days after minocycline therapy for acne was begun and resolved rapidly after discontinuation of the medication and start of oral predni...

journal_title：Journal of the American Academy of Dermatology

authors： Thibault MJ,Billick RC,Srolovitz H

更新日期：1992-11-01 00:00:00

abstract：:Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria and angioedema. The administration of thyroid hormone may alleviate chronic urticaria and/or angioedema in selected patients. This review focuses on the association of thyroid autoimmunity with chronic urticaria and/or angioede...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：1999-02-01 00:00:00

abstract：:A technique involving modification of the routine paraffin embedding procedure that allows immunohistochemical examination of extracellular antigens by light microscopy is described. The method is thus suitable for routine diagnostic immunofluorescence studies, permitting reliable, reproducible immunolabeling of immun...

journal_title：Journal of the American Academy of Dermatology

authors： Cerio R,MacDonald DM

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Laser resurfacing has been used for treatment of photoaged facial skin since late 1993. Very few long-term follow-up studies regarding the effectiveness and side effects of this procedure have been reported. METHOD:Patients who received carbon dioxide laser resurfacing for facial photoaging and wrinkling fr...

journal_title：Journal of the American Academy of Dermatology

authors： Manuskiatti W,Fitzpatrick RE,Goldman MP

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Biologics targeting interleukin 17A (IL-17A) allow for rapid clearance of psoriatic plaques, with a clinically favorable safety profile. OBJECTIVES:To compare the safety and efficacy of ixekizumab, an IL-17A antagonist, with the safety and efficacy of the IL-12/23 inhibitor ustekinumab through 52 weeks of t...

journal_title：Journal of the American Academy of Dermatology

authors： Paul C,Griffiths CEM,van de Kerkhof PCM,Puig L,Dutronc Y,Henneges C,Dossenbach M,Hollister K,Reich K

更新日期：2019-01-01 00:00:00

abstract：:A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

journal_title：Journal of the American Academy of Dermatology

authors： King DH

更新日期：1988-01-01 00:00:00

abstract：:Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...

journal_title：Journal of the American Academy of Dermatology

authors： Chapel TA,Mehregan AH,Reyman TA

更新日期：1981-01-01 00:00:00

abstract：:Many cutaneous diseases have been reported in patients with human immunodeficiency virus infection. We report two patients with pityriasis rubra pilaris and human immunodeficiency virus infection. In one patient, the onset of pityriasis rubra pilaris preceded the discovery of human immunodeficiency virus infection. In...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Nahass GT,Pardo RJ,Kerdel FA

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Few studies have reported the accuracy of measures used to assess sun-protection practices. Valid measures are critical to the internal validity and use of skin cancer control research. OBJECTIVES:We sought to validate self-reported covering-up practices of pool-goers. METHODS:A total of 162 lifeguards and...

journal_title：Journal of the American Academy of Dermatology

authors： O'Riordan DL,Nehl E,Gies P,Bundy L,Burgess K,Davis E,Glanz K

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae infection is associated with extrapulmonary complications, including mucocutaneous eruptions. These eruptions, which have been termed either "Stevens-Johnson syndrome" or "erythema multiforme" in the literature, may differ from drug-induced Stevens-Johnson syndrome or viral-associated e...

journal_title：Journal of the American Academy of Dermatology

authors： Canavan TN,Mathes EF,Frieden I,Shinkai K

更新日期：2015-02-01 00:00:00

abstract：:The most common active ingredient in hair coloring is para-phenylenediamine (PPDA), which can produce contact dermatitis, particularly in persons who dye their scalp hair and in hairdressers. We have identified another group of patients also at risk, namely men from Arab countries, who commonly grow beards and dye the...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu TS,Davis MD,el-Azhary R,Corbett JF,Gibson LE

更新日期：2001-05-01 00:00:00

abstract：:The usual method of treatment of pilomatricoma (calcifying epitheliona of Malherbe) is excision. We present a review of eight patients with ten tumors treated by incision and curettement. Follow-up ranged from 1 to 10 years, and there have been no recurrences. An alternative method of therapy with excellent results is...

journal_title：Journal of the American Academy of Dermatology

authors： Morales A,McGoey J

更新日期：1980-01-01 00:00:00

abstract：:We describe a 3-year-old male patient with an unusual congenital lesion on the plantar surface of the left foot that had been asymptomatic until shortly before presentation. Histologic examination of the plaque revealed a thinner keratin layer, increased pigmentation, and a pilosebaceous unit with a visible vellus hai...

journal_title：Journal of the American Academy of Dermatology

authors： Dragan L,Lorincz AL,Medenica MM,Phillips SB

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immune evasion. OBJECTIVE:Determine whether aspirin confers longer survival in patients with melanoma. METHODS:A retrospective cohort study of 1522 patients at Indiana University Health who had melanoma diag...

journal_title：Journal of the American Academy of Dermatology

authors： Rachidi S,Wallace K,Li H,Lautenschlaeger T,Li Z

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Carney complex (CNC) is an autosomal dominant disorder associated with multiple neoplasms. OBJECTIVE:We report a case of a 40-year-old Caucasian man with a sporadic form of CNC. METHODS:This is a clinicopathologic description and molecular biological study with an emphasis on histopathologic findings. RES...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Sima R,Michal M,Hes O,Roucka P,Zarybnicka M,Hora M,Chudacek Z,Kazakov DV

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Epidermal necrolysis (EN) involving ≥10% of the body surface area (BSA) is often complicated by bacterial infections. OBJECTIVE:We sought to describe the epidemiology of bloodstream infections (BSIs) in EN involving a BSA ≥10% and the diagnostic performances of skin cultures for predicting the pathogen(s) i...

journal_title：Journal of the American Academy of Dermatology

authors： Lecadet A,Woerther PL,Hua C,Colin A,Gomart C,Decousser JW,Mekontso Dessap A,Wolkenstein P,Chosidow O,de Prost N,Ingen-Housz-Oro S

更新日期：2019-08-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and...

journal_title：Journal of the American Academy of Dermatology

authors： Cotton J,Armstrong DJ,Wedig R,Hood AF

更新日期：1998-11-01 00:00:00

abstract：:In this article we focus on updates in select etiologies of retiform purpura. These causes of retiform purpura, in addition to bacterial or fungal sepsis, disseminated intravascular coagulation, purpura fulminans, and catastrophic antiphospholipid syndrome, are important diagnoses with potential for morbidity and mort...

journal_title：Journal of the American Academy of Dermatology

authors： Georgesen C,Fox LP,Harp J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Mohs micrographic surgery is thought to be a useful therapy for cutaneous melanoma. Controversy persists, however, because there are few published reports that document its safety and efficacy. OBJECTIVE:Our purpose was to determine the safety and efficacy of Mohs micrographic surgery for the treatment of c...

journal_title：Journal of the American Academy of Dermatology

authors： Zitelli JA,Brown C,Hanusa BH

更新日期：1997-08-01 00:00:00

abstract：:A systematic, uniform evaluation of 102 patients with, or at risk for, neurofibromatosis has shown that café au lait spots (CLS), even in large numbers, may not be sufficient to diagnose this disorder, and that several other dermatologic features may provide clues to its pathogenesis. These features include pruritus a...

journal_title：Journal of the American Academy of Dermatology

authors： Riccardi VM

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Skin ulcers are common vascular complications of systemic sclerosis (SSc). OBJECTIVE:The aim of the study was to identify clinical, biologic, and imaging parameters that constitute risk factors for the occurrence and persistence of skin ulcers. METHODS:One hundred thirty Italian SSc patients were examined ...

journal_title：Journal of the American Academy of Dermatology

authors： Alivernini S,De Santis M,Tolusso B,Mannocci A,Bosello SL,Peluso G,Pinnelli M,D'Antona G,La Torre G,Ferraccioli G

更新日期：2009-03-01 00:00:00