Histologic findings in mummified skin.

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The use of cutaneous resurfacing lasers to treat rhytides is widely accepted. Several carbon dioxide lasers, many using fundamentally different technologies, are available. OBJECTIVE:The purpose of this study was to compare the results obtained and side effects after treating rhytides with 3 different carbo...

journal_title：Journal of the American Academy of Dermatology

authors： Gross EA,Rogers GS

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Non-adherence rates are high among patients with psoriasis, partly because of discordance between recommended treatments and individual preferences. OBJECTIVES:Our aim was to assess the impact of comorbidities on patients' preferences for psoriasis treatments. METHODS:A computer-based conjoint analysis exp...

journal_title：Journal of the American Academy of Dermatology

authors： Schmieder A,Schaarschmidt ML,Umar N,Terris DD,Goebeler M,Goerdt S,Peitsch WK

更新日期：2012-09-01 00:00:00

abstract：:Most clinicians agree that mycosis fungoides is the prototypic cutaneous T cell lymphoma. However, certain clinical characteristics indicate that this disorder may begin as a reactive rather than a neoplastic process. The concept of a nonneoplastic etiopathogenesis of mycosis fungoides is further supported by recent d...

journal_title：Journal of the American Academy of Dermatology

authors： Thiers BH

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. OBJECTIVE:To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. METHODS:...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA,Whiting DA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Biologics targeting interleukin 17A (IL-17A) allow for rapid clearance of psoriatic plaques, with a clinically favorable safety profile. OBJECTIVES:To compare the safety and efficacy of ixekizumab, an IL-17A antagonist, with the safety and efficacy of the IL-12/23 inhibitor ustekinumab through 52 weeks of t...

journal_title：Journal of the American Academy of Dermatology

authors： Paul C,Griffiths CEM,van de Kerkhof PCM,Puig L,Dutronc Y,Henneges C,Dossenbach M,Hollister K,Reich K

更新日期：2019-01-01 00:00:00

abstract：:Because Of Increasing Concern With The Ethical Challenges To Physicians In Recent Years, A Committee Of The Council Of Medical Specialty Societies (CMSS), Under The Chairmanship Of Sara C. Charles, Md, Organized A 2-DAY Symposium On The Ethic Of Medicine In April 1997. During This Conference 6 Workgroup Sessions Were ...

journal_title：Journal of the American Academy of Dermatology

authors： Sams WM

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:It is unsettled whether small plaque parapsoriasis (SPP) represents an inflammatory dermatosis or has a potential to transform into mycosis fungoides (MF) or is, in fact, MF. The literature contains no fully documented example of progression of SPP into MF. OBJECTIVE:The purpose of our study was to present ...

journal_title：Journal of the American Academy of Dermatology

authors： Belousova IE,Vanecek T,Samtsov AV,Michal M,Kazakov DV

更新日期：2008-09-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE). OBJECTIVE:We describe the clinical and histopathologic differences between the two diseases. METHODS:We reviewed clinical findings and histopathologic changes in two c...

journal_title：Journal of the American Academy of Dermatology

authors： Chun SI,Ji HG

更新日期：1992-12-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00

abstract：:Twenty undifferentiated skin tumors were examined by immunostaining in an attempt to achieve more precise identification. Light microscopy yielded only a differential diagnosis, whereas immunostaining of formalin-fixed, paraffin-embedded tissue sections with a panel of antibodies to intermediate filaments and other ce...

journal_title：Journal of the American Academy of Dermatology

authors： Kahn H,Baumal R,From L

更新日期：1986-06-01 00:00:00

abstract：:A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lantos G,Fisher BK,Contreras M

更新日期：1988-12-01 00:00:00

abstract：:Infantile acropustulosis (IA) is a syndrome characterized by recurrent crops of 1- to 2-mm intensely pruritic vesicopustules that are found primarily on the distal extremities of infants. It is reportedly responsive to sulfones and unresponsive to other therapy, but if left untreated spontaneously resolves at about 2 ...

journal_title：Journal of the American Academy of Dermatology

authors： Jennings JL,Burrows WM

更新日期：1983-11-01 00:00:00

abstract：:We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case th...

journal_title：Journal of the American Academy of Dermatology

authors： Umbert IJ,Su WP

更新日期：1989-12-01 00:00:00

abstract：:Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

journal_title：Journal of the American Academy of Dermatology

authors： Wester RC,Bucks DA,Maibach HI

更新日期：1983-05-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE:This study was conducted to evaluate the efficacy and safety of BTX-A treatment of glabellar lines. METHODS:Patients with moderate to severe glabellar lines at maximum frown received intramuscular inje...

journal_title：Journal of the American Academy of Dermatology

authors： Carruthers JA,Lowe NJ,Menter MA,Gibson J,Nordquist M,Mordaunt J,Walker P,Eadie N,BOTOX Glabellar Lines I Study Group.

更新日期：2002-06-01 00:00:00

abstract：:The second article in this continuing medical education series discusses cosmetic practices associated with cultural dermatoses, including hair care, traditional clothing, and skin decorations. Often, the steps individuals take to enhance their physical appearance are determined by cultural perceptions of beauty. With...

journal_title：Journal of the American Academy of Dermatology

authors： Vashi NA,Patzelt N,Wirya S,Maymone MBC,Kundu RV

更新日期：2018-07-01 00:00:00

abstract：:In a randomized, double-blind comparative study 60 patients with severe, widespread psoriasis were treated either with photochemotherapy (PUVA) alone or in combination with acitretin. Forty-eight patients completed the study; of these, 25 received placebo combined with PUVA and 23 received acitretin with PUVA. Marked ...

journal_title：Journal of the American Academy of Dermatology

authors： Tanew A,Guggenbichler A,Hönigsmann H,Geiger JM,Fritsch P

更新日期：1991-10-01 00:00:00

abstract：:The literature concerning the use and possible mode of action of thalidomide in reactional lepromatous leprosy and in various other conditions is reviewed. Although it has no action against the leprosy bacillus, its value in the treatment of the adverse reactions in this type of leprosy is well established, many lepro...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,McDougall AC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Rituximab (RTX) is an effective therapy for patients with pemphigus; however, the therapy does not prevent relapse. OBJECTIVES:To compare early relapsing patients (before 12 months) and late relapsing patients (after 24 months) following RTX therapy. METHOD:In this prospective study, 19 patients were enrol...

journal_title：Journal of the American Academy of Dermatology

authors： Saleh MA

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Patients with onychomycosis may experience physical impairment and psychological and social limitations related to their infection. OBJECTIVE:The object of this study was to compare health-related quality-of-life scores of patients with onychomycosis with those of a control group. METHODS:The interview ins...

journal_title：Journal of the American Academy of Dermatology

authors： Lubeck DP

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Intraoperative pain during Mohs micrographic surgery (MMS) has not been characterized. However, many patients report postoperative pain on the day of MMS. OBJECTIVE:We sought to determine if patients experience pain during their MMS visit. METHODS:In phase I of this study, patients were asked to report int...

journal_title：Journal of the American Academy of Dermatology

authors： Connolly KL,Nehal KS,Dusza SW,Rossi AM,Lee EH

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Although most patients with cutaneous melanoma are non-Hispanic whites (NHWs), minorities consistently suffer worse melanoma-specific survival (MSS). Much of the literature comes from analyses of registries from the 1990s and 2000s. OBJECTIVE:We sought to evaluate whether and to what degree racial disparity...

journal_title：Journal of the American Academy of Dermatology

authors： Qian Y,Johannet P,Sawyers A,Yu J,Osman I,Zhong J

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway activation in sarcoidosis, suggesting that JAK inhibition might be effective. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Damsky W,Thakral D,McGeary MK,Leventhal J,Galan A,King B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Few studies have evaluated the relationship between hidradenitis suppurativa (HS) and type 2 diabetes mellitus (T2DM), and the existing data show conflicting results. OBJECTIVE:To determine the prevalence of T2DM among patients with HS and identify at-risk demographic subgroups. METHODS:Cross-sectional ana...

journal_title：Journal of the American Academy of Dermatology

authors： Garg A,Birabaharan M,Strunk A

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Onychomycosis is an increasing problem with limited therapeutic options. OBJECTIVE:We evaluated the safety and efficacy, of oral terbinafine, a new fungicidal antimycotic, in patients with toenail onychomycosis. METHODS:A North American multicenter, double-blind, placebo-controlled study evaluated the myco...

journal_title：Journal of the American Academy of Dermatology

authors： Drake LA,Shear NH,Arlette JP,Cloutier R,Danby FW,Elewski BE,Garnis-Jones S,Giroux JM,Gratton D,Gulliver W,Hull P,Jones HE,Journet M,Krol AL,Leyden JJ,Maddin SC,Ross JB,Savin RC,Scher RK,Sibbald GR,Tawfik NH,Zaia

更新日期：1997-11-01 00:00:00

abstract：:Alendronate is a bisphosphonate compound used to treat diseases of pathologic bone resorption. Cutaneous reactions to this medication are rare. We report the case of a superficial gyrate erythema that occurred as a reaction to weekly alendronate therapy used in the treatment of postmenopausal osteoporosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Cohen JB,Wetherington W,Cockerell CJ

更新日期：2003-06-01 00:00:00