In vivo percutaneous absorption of hydrocortisone in psoriatic patients and normal volunteers.

abstract：:We present a case of cutaneous infection due to Cladophialophora bantiana, an agent of phaeohyphomycosis. The patient developed a nodule with pustule formation on the dorsum of the left hand; no trauma was reported. The lesion was successfully treated with itraconazole and surgical excision. Histopathologically, there...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Warren NG,Kelly LW

更新日期：1999-02-01 00:00:00

abstract：:The occurrence of Langerhans cell histiocytosis (LCH) and malignancy in the same patient is rare. When LCH occurs concomitantly with acute leukemia, distinct temporal patterns often exist; acute myelogenous leukemia (AML) typically succeeds LCH, whereas acute lymphocytic leukemia (ALL) usually precedes it. We report a...

journal_title：Journal of the American Academy of Dermatology

authors： Chiles LR,Christian MM,McCoy DK,Hawkins HK,Yen AH,Raimer SS

更新日期：2001-12-01 00:00:00

abstract：:An unusual American epidemic consisting of twenty cases of granuloma inguinale is chronicled. Evidence from this series supports the venereal transmission of the disorder. Trimethoprim/sulfamethoxazole proved to be a safe and effective therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Tschen JA,Ramsdell W,Moore J,Markham B

更新日期：1984-09-01 00:00:00

abstract：:A concept of dichotomous types of segmental involvement of autosomal dominant skin disorders has recently been proposed. Among the different types of porokeratosis, disseminated superficial actinic porokeratosis is known to be an autosomal dominant skin disorder, and linear porokeratosis represents the segmental form ...

journal_title：Journal of the American Academy of Dermatology

authors： Freyschmidt-Paul P,Hoffmann R,König A,Happle R

更新日期：1999-10-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：:The presence of the discoid lupus erythematosus (DLE) skin lesion in a patient with systemic lupus erythematosus (SLE) has been suggested to be a marker of less frequent and less severe renal disease. The clinical and laboratory features of seventeen patients who were seen in a dermatology practice and who had DLE as ...

journal_title：Journal of the American Academy of Dermatology

authors： Callen JP

更新日期：1985-02-01 00:00:00

abstract：:Calcinosis cutis is the deposition of insoluble calcium salts in the skin and subcutaneous tissue. We report the case of a 28-year-old Caucasian woman with cystic fibrosis in whom strikingly symmetrical and reticulate calcinosis cutis developed on the lower extremities, which was noted on histology to spare the eccrin...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman JS,Fulghum Walters R,Woosley J,Fine JD

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Serum levels of S100A8/A9 may correlate with disease activity in psoriasis. OBJECTIVE:We sought to elucidate the association of serum levels of S100A8/A9 heterodimers with the clinical subtypes of psoriasis and the major cell source. METHODS:Serum samples were collected from patients with psoriasis vulgari...

journal_title：Journal of the American Academy of Dermatology

authors： Aochi S,Tsuji K,Sakaguchi M,Huh N,Tsuda T,Yamanishi K,Komine M,Iwatsuki K

更新日期：2011-05-01 00:00:00

abstract：:Pressure ulcers are localized areas of tissue necrosis that result from unrelieved pressure. They are graded or staged according to the degree of tissue damage observed. The main etiologic factors include pressure, shearing forces, friction, and moisture. The clinical course may be complicated by several conditions in...

journal_title：Journal of the American Academy of Dermatology

authors： Kanj LF,Wilking SV,Phillips TJ

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Onychomycosis (fungal infection of the toenails or fingernails) is common, affecting up to 8% of the general population. Telephone and mailed surveys conducted to study this disease are usually completed via patient self-report. The validity of the counts of diseased nails reported by the patients participat...

journal_title：Journal of the American Academy of Dermatology

authors： Cham PM,Chen SC,Grill JP,Warshaw EM

更新日期：2008-01-01 00:00:00

abstract：:Lupus pernio has been associated with sarcoidosis of the upper respiratory tract. The semantic differences in the use of the designation "lupus pernio" are such that American dermatologists may not consider patients with nasal rim papules of sarcoidosis to have lupus pernio. During a 12-month period, we referred each ...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo JL,Koufman JA,Thompson JN,White WL,Shar GG,Schreiner DJ

更新日期：1990-03-01 00:00:00

abstract：:Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The precise cause of melasma remains unknown; however, there are many possible contributing factors. Because of its dermal component and tendency to relapse, melasma is...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Gover MD,Nouri K,Taylor S

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway activation in sarcoidosis, suggesting that JAK inhibition might be effective. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Damsky W,Thakral D,McGeary MK,Leventhal J,Galan A,King B

更新日期：2020-03-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：:Onycholysis (ONY) of the fingernails is a common disorder that is diagnosed with ease but often managed with great difficulty. The full spectrum of causes is broad and not always readily apparent. In this review, an approach to the evaluation and management of ONY is offered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kechijian P

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：:Chronic herpesvirus infections are common in patients infected with HIV. Atypical skin lesions secondary to long-standing varicella-zoster virus (VZV) infection have been reported. We present a case of an AIDS patient with a chronic VZV infection that simulated a basal cell carcinoma. Histologic examination and immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Tsao H,Tahan SR,Johnson RA

更新日期：1997-05-01 00:00:00

abstract：:We report the case of an 84-year-old white male who underwent vermilionectomy for removal of a tumor, which proved to be squamous cell carcinoma. Chelitis glandularis related to marked actinic damage was noted at a subsequent visit. The presence of chelitis glandularis should be investigated for the presence of neopla...

journal_title：Journal of the American Academy of Dermatology

authors： Carrington PR,Horn TD

更新日期：2006-02-01 00:00:00

abstract：:Follicular mucinosis is often associated with mycosis fungoides and has been rarely observed to occur with other neoplastic and inflammatory conditions. We describe a 60-year-old patient with follicular mucinosis who later developed acute myelogenous leukemia. This is the first reported case of follicular mucinosis as...

journal_title：Journal of the American Academy of Dermatology

authors： Sumner WT,Grichnik JM,Shea CR,Moore JO,Miller WS,Burton CS

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Inability of topical medications to penetrate via nail plate brings a great challenge to clinicians in treating onychomycosis. Furthermore, oral medications are not appropriate for all patients because of drug interactions, adverse effects, and contraindications. OBJECTIVE:We sought to evaluate the clinical...

journal_title：Journal of the American Academy of Dermatology

authors： Bhatta AK,Keyal U,Huang X,Zhao JJ

更新日期：2016-05-01 00:00:00

abstract：:Direct immunofluorescence microscopy was positive in 88% of forty-one skin biopsy specimens from thirty-four patients with the clinical diagnosis of erythema multiforme. The most common finding, present in 67% of positive specimens, was the cytoid body, or fluorescent keratinocyte, which stained most often with IgM (h...

journal_title：Journal of the American Academy of Dermatology

authors： Finan MC,Schroeter AL

更新日期：1984-03-01 00:00:00

abstract：:Three young and middle-aged patients developed severe bullous eruption after receiving various penicillins. The clinical findings included high fever, prostration, widespread bullous eruption mainly on the head, face, and extremities, targetlike lesions on the palms and soles, and severe erosions in almost all the muc...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,David M,Ingber A,Hazaz B,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00

abstract：:Cutaneous surgery has become critical to comprehensive dermatologic care, and dermatologists must therefore be equipped to manage the risks associated with surgical procedures. As complications may occur at any point along the continuum of care, assessing, managing and preventing risk from beginning to end becomes ess...

journal_title：Journal of the American Academy of Dermatology

authors： Strickler AG,Shah P,Bajaj S,Mizuguchi R,Nijhawan RI,Odueyungbo M,Rossi A,Ratner D

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:Dermatitis herpetiformis (DH) is highly associated with celiac disease. Recently, tissue transglutaminase (tTG) was identified as the autoantigen of IgA antibodies in celiac disease. The prevalence of antibodies to tTG in DH patients is not known. OBJECTIVE:The purpose of this study was to determine whether...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Dieterich W,Bröcker EB,Schuppan D,Zillikens D

更新日期：1999-12-01 00:00:00

abstract：:Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification, metastatic calcification, idiopathic calcification, iatrogenic calcification, and calciphylaxis. Dystrophic calcification appears a...

journal_title：Journal of the American Academy of Dermatology

authors： Reiter N,El-Shabrawi L,Leinweber B,Berghold A,Aberer E

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The histopathological and clinical overlapping features between condyloma acuminata and bowenoid papulosis can present a diagnostic challenge and we sought to determine if immunochemistry can be helpful in this setting. OBJECTIVE:In this study, we evaluate the specificity and sensitivity of p16 immunohistoc...

journal_title：Journal of the American Academy of Dermatology

authors： Kazlouskaya V,Shustef E,Allam SH,Lal K,Elston D

更新日期：2013-09-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：:We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully ...

journal_title：Journal of the American Academy of Dermatology

authors： Gardeazábal J,Arregui MA,Gil N,Landa N,Ratón JA,Diáz-Pérez JL

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Giant angiofibromas in patients with tuberous sclerosis complex (TSC) are rare. OBJECTIVE:We sought to report two patients who had TSC with unusually large and disfiguring facial angiofibromas and to identify underlying histopathologic changes that may possibly explain the clinical features. METHODS:We per...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Kerl K,Michal M,Filipova H,Vrtel R,Vanecek T,Zelenakova H,Kraus J,Kodet R,Kazakov DV

更新日期：2012-12-01 00:00:00