Calcinosis cutis: part I. Diagnostic pathway.

abstract：BACKGROUND:Multiple myeloma (MM) is a plasma cell dyscrasia characterized by a clonal proliferation of plasma cells that produces a monoclonal protein. There are dermatologic disorders that have been associated with MM, such as amyloidosis, cryoglobulinemia, POEMS syndrome, normolipemic plane xanthoma, and plasmacytoma...

journal_title：Journal of the American Academy of Dermatology

authors： Bayer-Garner IB,Smoller BR

更新日期：2003-04-01 00:00:00

abstract：:Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin. Recent advances in the immunopathogenesis and genetics of psoriasis have broadened our understanding of psoriasis. Psoriasis is now considered a systemic inflammatory condition analogous to other inflammatory immune disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kremers HM,McEvoy MT,Dann FJ,Gabriel SE

更新日期：2007-08-01 00:00:00

abstract：:A PABA ester-oxybenzone preparation is superior to PABA or sulisobenzone alone in protecting the skin from methoxsalen-induced ultraviolet A (UVA) phototoxicity after water substantivity challenge. Such a mixture would be useful as a UVA screen for uninvolved or actinically damaged skin in patients receiving psoralens...

journal_title：Journal of the American Academy of Dermatology

authors： Jarratt M,Hill M,Smiles K

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVE:We sought to develop a validated, reliable pruritus-specific quality-of-life (QOL) instrument, ItchyQoL. METHODS:From 21 in-depth interviews with patients with pruritus, we developed 22 pruritus-specific items, and hypothesized 3 major constructs that explain the way pruritus affects patients' QOL: symptoms,...

journal_title：Journal of the American Academy of Dermatology

authors： Desai NS,Poindexter GB,Monthrope YM,Bendeck SE,Swerlick RA,Chen SC

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Nickel is a common allergen. OBJECTIVE:To examine the epidemiology of nickel sensitivity in North America. METHODS:Retrospective, cross-sectional analysis of 44,097 patients patch tested by the North American Contact Dermatitis Group from 1994 to 2014. Nickel sensitivity was defined as a positive patch tes...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Zhang AJ,DeKoven JG,Maibach HI,Belsito DV,Sasseville D,Fowler JF Jr,Fransway AF,Mathias T,Pratt MD,Marks JG Jr,Zug KA,Zirwas MJ,Taylor JS,DeLeo VA

更新日期：2019-03-01 00:00:00

abstract：:This review begins with a classification of adverse drug reactions and a summary of those features that distinguish allergic from toxic and idiosyncratic reactions. Factors that influence the risk of developing drug allergy are then reviewed, followed by a discussion of the known and suspected immunologic mechanisms r...

journal_title：Journal of the American Academy of Dermatology

authors： VanArsdel PP Jr

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:A number of factors other than those identified by the American Joint Committee on Cancer (AJCC) may have prognostic significance in the evaluation of melanoma. OBJECTIVE:We sought to evaluate commonly recorded clinical features potentially associated with aggressive melanoma. METHODS:We conducted a retros...

journal_title：Journal of the American Academy of Dermatology

authors： Donahue T,Lee CY,Sanghvi A,Obregon R,Sidiropoulos M,Cooper C,Merkel EA,Yélamos O,Ferris L,Gerami P

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The formulation of topical dermatologic products must take into account efficacy, safety, and patient compliance. OBJECTIVE:We describe how an aqueous gel containing adapalene, a novel naphthoic acid derivative was selected for the topical treatment of acne. METHODS AND RESULTS:Dose selection was made usin...

journal_title：Journal of the American Academy of Dermatology

authors： Allec J,Chatelus A,Wagner N

更新日期：1997-06-01 00:00:00

abstract：:We report two cases of mycosis fungoides with marked, pleomorphic follicular manifestations. Follicular hyperkeratosis, comedo-like lesions, acquired epidermal cysts, and patchy alopecia developed in various locations in both patients. Findings of histopathologic and immunohistochemical studies showed atypical CD4+ T ...

journal_title：Journal of the American Academy of Dermatology

authors： Lacour JP,Castanet J,Perrin C,Ortonne JP

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Patients with cutaneous lupus erythematosus (LE) and a history of disease- related photoaggravation, confirmed by phototesting, may not respond to photoprotection and/or medical intervention. Ultraviolet B-hardening therapy may improve tolerance for environmental ultraviolet radiation (UVR) in photosensitive...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders CJ,Lam HY,Bruijnzeel-Koomen CA,Sigurdsson V,van Weelden H

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The difficulties in accurately assessing pigmented skin lesions are ever present in practice. The recently described ABCD rule of dermatoscopy (skin surface microscopy at x10 magnification), based on the criteria asymmetry (A), border (B), color (C), and differential structure (D), improved diagnostic accura...

journal_title：Journal of the American Academy of Dermatology

authors： Nachbar F,Stolz W,Merkle T,Cognetta AB,Vogt T,Landthaler M,Bilek P,Braun-Falco O,Plewig G

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) often displays extensive subclinical spread. Mohs micrographic surgery (MMS) has been proposed to help delineate the true histologic margin; however, visualizing atypical melanocytes on frozen section is challenging and often requires confirmatory permanent paraffin sections. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Kelley LC,Starkus L

更新日期：2002-01-01 00:00:00

abstract：:Isotretinoin is used to treat severe and recalcitrant acne. Possible side effects include depression, suicide, and suicidal ideation; however, other studies suggest isotretinoin may improve mood and quality of life. Although iPLEDGE consenting warns about the risk of depression and suicidal ideation, there is no recom...

journal_title：Journal of the American Academy of Dermatology

authors： Schrom K,Nagy T,Mostow E

更新日期：2016-07-01 00:00:00

abstract：:The case presented here involves a 32-year-old homosexual man with human immunodeficiency virus (HIV) seropositivity and unusual manifestations of secondary syphilis. The patient presented with syphilitic keratoderma and chorioretinitis, and his appearance superficially resembled that of a patient with Reiter's syndro...

journal_title：Journal of the American Academy of Dermatology

authors： Radolf JD,Kaplan RP

更新日期：1988-02-01 00:00:00

abstract：:George Cheyne Shattuck's 1808 dissertation on structure and function of the skin is one of the earliest American writings on the topic of skin diseases. Although this essay contributed no important new observations, it does provide insight into the attitudes of American physicians in the post-Revolutionary War period ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine MC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

journal_title：Journal of the American Academy of Dermatology

authors： Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Associations between gluten intake and psoriasis, psoriatic arthritis, and atopic dermatitis are poorly understood. OBJECTIVE:To determine whether increased gluten intake is associated with incident psoriasis, psoriatic arthritis, and atopic dermatitis. METHODS:Cohort studies among women in Nurses' Health ...

journal_title：Journal of the American Academy of Dermatology

authors： Drucker AM,Qureshi AA,Thompson JM,Li T,Cho E

更新日期：2020-03-01 00:00:00

abstract：:Angiolymphoid hyperplasia with eosinophilia developed in a 13-year-old boy. The immune phenotype of infiltrating cells and the distribution of adhesion molecules of the integrin, immunoglobulin, and selectin families were analyzed with monoclonal antibodies. The infiltrate consisted mainly of helper lymphocytes, monoc...

journal_title：Journal of the American Academy of Dermatology

authors： von den Driesch P,Gruschwitz M,Schell H,Sterry W

更新日期：1992-05-01 00:00:00

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a disease with both inherited and environmental components determining its clinical expression, has been reported to be more frequent in people of Asian origin. OBJECTIVE:Our purpose was to compare the 12-month cumulative incidence of AD in Caucasian, Chinese, and Vietnamese babies b...

journal_title：Journal of the American Academy of Dermatology

authors： Mar A,Tam M,Jolley D,Marks R

更新日期：1999-04-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：:Angioma serpiginosum is a rare condition that involves both the proliferation and dilatation of superficial blood vessels in the skin. It classically begins in childhood, is more common in females, and is asymptomatic. Typical lesions appear on the extremities and are often asymmetric. We report a case of angioma serp...

journal_title：Journal of the American Academy of Dermatology

authors： Katta R,Wagner A

更新日期：2000-02-01 00:00:00

abstract：:Three patients with advanced atherosclerotic vascular disease developed multiple cholesterol emboli. The clinical presentation typically includes livedo reticularis of the lower part of the body and purple toes. Small areas of necrosis and ulceration may be present distally, despite palpable pulses. Muscular and abdom...

journal_title：Journal of the American Academy of Dermatology

authors： Kalter DC,Rudolph A,McGavran M

更新日期：1985-08-01 00:00:00

abstract：:The standard definition of itching (as "an unpleasant sensation that provokes the desire to scratch") takes no account of recent advances in knowledge about itch physiology. Always imprecise, this definition is also out-of-date. Its defects are discussed in this article, and some modifications are proposed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Savin JA

更新日期：1998-08-01 00:00:00

abstract：:Conventional chemotherapy continues to be an important part of cancer management, but may cause various cutaneous reactions because it disturbs specific cell cycle phases. The alkylating agents cyclophosphamide, ifosfamide, and thiotepa can produce hyperpigmentation, while hypersensitivity reactions can be seen with p...

journal_title：Journal of the American Academy of Dermatology

authors： Reyes-Habito CM,Roh EK

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Melanoma in African Americans is rare, and the diagnosis is often delayed, leading to advanced presentation and poor prognosis. OBJECTIVE:The purpose of this retrospective study is to determine whether African American patients diagnosed with melanoma at the Washington Hospital Center were initially seen wi...

journal_title：Journal of the American Academy of Dermatology

authors： Byrd KM,Wilson DC,Hoyler SS,Peck GL

更新日期：2004-01-01 00:00:00

abstract：:We discuss a metastatic dermatofibrosarcoma protuberans on the occiput of a 53-year-old man whose initial tumor appeared on his forehead 23 years previously. The pathology of the tumor that recurred at the initial site was fibrosarcomatous dermatofibrosarcoma protuberans, whereas the metastatic tumor was a pigmented d...

journal_title：Journal of the American Academy of Dermatology

authors： Kabumoto T,Fujiwara H,Kariya N,Tsujimoto T,Ito K,Ito M,Kobayashi H

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:The current standard tool for diagnosing allergic contact dermatitis (ACD) in the United States is the T.R.U.E. test panels, which consist of 23 allergens. Previous studies have raised concern regarding the adequacy of these panels in fully assessing patients with possible ACD. OBJECTIVE:We sought to examin...

journal_title：Journal of the American Academy of Dermatology

authors： Saripalli YV,Achen F,Belsito DV

更新日期：2003-07-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Mouse studies show that tumor-derived prostaglandins and platelets promote melanoma progression and immune evasion. OBJECTIVE:Determine whether aspirin confers longer survival in patients with melanoma. METHODS:A retrospective cohort study of 1522 patients at Indiana University Health who had melanoma diag...

journal_title：Journal of the American Academy of Dermatology

authors： Rachidi S,Wallace K,Li H,Lautenschlaeger T,Li Z

更新日期：2018-05-01 00:00:00