Cutaneous reactions to chemotherapeutic drugs and targeted therapies for cancer: part I. Conventional chemotherapeutic drugs.

abstract：:We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone. Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone antibodies. Immunoelectron microscopy demonstrated binding...

journal_title：Journal of the American Academy of Dermatology

authors： Tamada Y,Yokochi K,Nitta Y,Ikeya T,Hara K,Owaribe K

更新日期：1995-05-01 00:00:00

abstract：:A recent study demonstrated that hirsute women with irregular menses had higher levels of serum androgens that hirsute women with regular menses. To investigate this finding, we measured total testosterone, biologically active testosterone, free testosterone, androstenedione, dehydroepiandrosterone, and dehydroepiandr...

journal_title：Journal of the American Academy of Dermatology

authors： Salman K,Spielvogel RL,Miller JL,Rose LI

更新日期：1991-03-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature. OBJECTIVE:To provide up-to-date information regarding the state of teledermatology programs in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Wu J,Kovarik CL,Goldyne ME,Oh DH,McKoy KC,Shippy AM,Pak HS

更新日期：2012-11-01 00:00:00

abstract：:We report on a patient with a syndrome characterized by smooth facial papules and nodules; alopecia of the eyebrows, eyelashes, and most body hair; mild alopecia of scalp hair; possibly hypohidrosis; and myasthenia gravis. The clinical, histologic, and immunohistochemical findings are compared with classic and desmopl...

journal_title：Journal of the American Academy of Dermatology

authors： Starink TM,Lane EB,Meijer CJ

更新日期：1986-11-01 00:00:00

abstract：:Lipoatrophic panniculitis likely represents a group of disorders characterized by an inflammatory panniculitis followed by lipoatrophy. It occurs locally in a variety of settings and has been reported in the literature under various terms, including annular atrophic connective tissue panniculitis of the ankles, annula...

journal_title：Journal of the American Academy of Dermatology

authors： Dimson OG,Esterly NB

更新日期：2006-02-01 00:00:00

abstract：:Arthropod bites remain a major cause of patient morbidity. These bites can cause local or systemic effects that may be infectious or inflammatory in nature. Arthropods, notably insects and arachnids, are vectors of potentially serious ailments including malaria, West Nile virus, dengue, and Lyme disease. Measures to c...

journal_title：Journal of the American Academy of Dermatology

authors： Katz TM,Miller JH,Hebert AA

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Melanoma in African Americans is rare, and the diagnosis is often delayed, leading to advanced presentation and poor prognosis. OBJECTIVE:The purpose of this retrospective study is to determine whether African American patients diagnosed with melanoma at the Washington Hospital Center were initially seen wi...

journal_title：Journal of the American Academy of Dermatology

authors： Byrd KM,Wilson DC,Hoyler SS,Peck GL

更新日期：2004-01-01 00:00:00

abstract：:Several technics for immunofluorescent staining have been described in the literature and are presently used by laboratories performing direct and indirect tissue immunofluorescence. The purpose of this communication is to describe a simple immunofluorescent technic that uses a five-slide polypropylene slide mailer co...

journal_title：Journal of the American Academy of Dermatology

authors： Grimwood RE,Huff JC,Weston W

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The potential for wrong-site surgery is a growing concern in dermatology. OBJECTIVE:The purpose of this study was to determine the incidence of difficulty with surgical site identification and possible confounding factors. METHODS:This was a prospective study on 333 Mohs cases performed between April 1, 20...

journal_title：Journal of the American Academy of Dermatology

authors： Rossy KM,Lawrence N

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies. OBJECTIVE:We sought to investigate the effects of alcohol and smoking on incident psoriasis. METHODS:Alcohol consumption, ...

journal_title：Journal of the American Academy of Dermatology

authors： Dai YX,Wang SC,Chou YJ,Chang YT,Chen TJ,Li CP,Wu CY

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：:We present further evidence that granuloma annulare and autoimmune thyroiditis may be associated. Only 11 cases have been previously reported with this association as far as we know. It may be advantageous to consider checking the thyroid-stimulating hormone and/or antithyroid antibodies before administering medicatio...

journal_title：Journal of the American Academy of Dermatology

authors： Vázquez-López F,González-López MA,Raya-Aguado C,Pérez-Oliva N

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The identification of "normal" dermoscopic patterns of acquired melanocytic nevi provides better diagnostic accuracy for melanoma in people with black skin. OBJECTIVE:We sought to describe melanocytic lesions (numbers and anatomic distributions) in skin types V and VI compared with skin types I and II, acco...

journal_title：Journal of the American Academy of Dermatology

authors： Tuma B,Yamada S,Atallah ÁN,Araujo FM,Hirata SH

更新日期：2015-07-01 00:00:00

abstract：:Molecules of the extracellular matrix may influence the biologic behavior of basal cell keratinocytes. In the unwounded situation, basal cells are in contact with the basement membrane of the dermo-epidermal junction and eventually detach from this structure, move vertically, and differentiate. During wound healing th...

journal_title：Journal of the American Academy of Dermatology

authors： Woodley DT,O'Keefe EJ,Prunieras M

更新日期：1985-02-01 00:00:00

abstract：DISCLAIMER:Adherence to these guidelines will not ensure successful treatment in every situation. Furthermore, these guidelines should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propri...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Krowchuk DP,Leyden JJ,Lucky AW,Shalita AR,Siegfried EC,Thiboutot DM,Van Voorhees AS,Beutner KA,Sieck CK,Bhushan R,American Academy of Dermatology\/American Academy of Dermatology Association.

更新日期：2007-04-01 00:00:00

abstract：:Costs for dermatitis can be evaluated against the costs and potential benefits of patch testing on the basis of data available from several sources. Consideration of cost for an individual patient suggests that costs become neutral and benefits become positive if the dermatitis is persistent and multiple physician vis...

journal_title：Journal of the American Academy of Dermatology

authors： Rietschel RL

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：:In patients with psoriasis, there is an increased availability of drugs for treatment. However, there are important questions about drug safety for mothers with psoriasis and their fetuses. Currently, there are limited safety data for many of the medications used. In this article, we review current pregnancy risk info...

journal_title：Journal of the American Academy of Dermatology

authors： Lam J,Polifka JE,Dohil MA

更新日期：2008-08-01 00:00:00

abstract：:Polymorphous sweat gland carcinoma is an unusual, recently described variant of low-grade malignant adnexal neoplasm of the skin characterized by a prolonged clinical course and predilection for the extremities. We describe a case of recurrent polymorphous sweat gland carcinoma in a 56-year-old man who presented with ...

journal_title：Journal of the American Academy of Dermatology

authors： Ronnen M,Ben-Dor D,Huszar M

更新日期：2002-06-01 00:00:00

abstract：:Epidermolysis bullosa acquisita is a chronic, severe, subepidermal, blistering disease of the skin, characterized by marked resistance to topical and systemic therapy. This report concerns a well-documented case of a woman who had had epidermolysis bullosa acquisita for 6 years and had remained hospitalized continuous...

journal_title：Journal of the American Academy of Dermatology

authors： Crow LL,Finkle JP,Gammon WR,Woodley DT

更新日期：1988-11-01 00:00:00

abstract：:Benign lymphangiomatous papules of the skin are benign lymphatic proliferations that may arise in the skin after operation or radiation therapy. We report a case of benign lymphangiomatous papules of the skin that occurred in a patient 4 years after undergoing radiation therapy to the chest for adenocarcinoma of the b...

journal_title：Journal of the American Academy of Dermatology

authors： Wagamon K,Ranchoff RE,Rosenberg AS,Jaworsky C

更新日期：2005-05-01 00:00:00

abstract：:Clinical examination is critical for the diagnosis and identification of response to treatment. It is fortunate that technologies are continuing to evolve, enabling augmentation of classical clinical examination with noninvasive imaging modalities. This article discusses emerging technologies with a focus on digital p...

journal_title：Journal of the American Academy of Dermatology

authors： Schneider SL,Kohli I,Hamzavi IH,Council ML,Rossi AM,Ozog DM

更新日期：2019-04-01 00:00:00

abstract：:Preventing death from malignant melanoma is the most pressing issue in preventive dermatology in the United States because the mortality rate has increased markedly. Dermatologists, as the physicians best suited by training to identify early malignant melanoma, need to take the lead in developing a national project of...

journal_title：Journal of the American Academy of Dermatology

authors： Howell JB

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Renal allograft transplantation is associated with an increased incidence of malignant melanoma. The development of excess melanocytic nevi may be an indicator of this risk. OBJECTIVE:This study determines the prevalence of melanocytic nevi in children who have received renal allografts. METHODS:Total and ...

journal_title：Journal of the American Academy of Dermatology

authors： Smith CH,McGregor JM,Barker JN,Morris RW,Rigden SP,MacDonald DM

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial protein with adhesive properties for inflammatory cells including lymphocytes. Its role in skin disease and regulation in vivo are uncertain. OBJECTIVE:Our purpose was to determine expression of VCAM-1 in normal and inflamed skin and the effect on...

journal_title：Journal of the American Academy of Dermatology

authors： Groves RW,Ross EL,Barker JN,MacDonald DM

更新日期：1993-07-01 00:00:00

abstract：:Benign lymphangiomatous papules of the skin are considered reactive lymphatic proliferations either caused by disruption of the lymphatic flow or tissue damage produced by operation or radiation therapy. We report a 72-year-old woman with umbilical papules and vesicle-like lesions that led to the diagnosis of a large ...

journal_title：Journal of the American Academy of Dermatology

authors： Bodet D,Rodríguez-Cano L,Bartralot R,Mollet J,Medina A,Heras C,Bassas P,Huguet P,García-Patos V

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:T-cell receptor (TCR) clonality may help establish a diagnosis of mycosis fungoides (MF). Routine clonality analysis is performed by using a polymerase chain reaction TCR- gamma assay, yet with this method, 10% to 50% of T-cell lymphomas escape detection. TCR- beta gene rearrangement is an additional assay. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schachter O,Tabibian-Keissar H,Debby A,Segal O,Baum S,Barzilai A

更新日期：2020-11-01 00:00:00

abstract：:It is often stated that persons of Celtic origin have an increased risk of skin cancer, but the evidence for this is almost exclusively anecdotal. We believe that the possibility of the Celts being at greater risk of skin cancer has important implications with regard to management in particular and in assisting our un...

journal_title：Journal of the American Academy of Dermatology

authors： Long CC,Marks R

更新日期：1995-10-01 00:00:00