Abstract:
:The case presented here involves a 32-year-old homosexual man with human immunodeficiency virus (HIV) seropositivity and unusual manifestations of secondary syphilis. The patient presented with syphilitic keratoderma and chorioretinitis, and his appearance superficially resembled that of a patient with Reiter's syndrome. Although nontreponemal and treponemal tests for syphilis showed reactivity, the patient's humoral immune response to individual polypeptides of Treponema pallidum, measured by Western blot analysis, was markedly abnormal. The possible relationship between asymptomatic HIV infection and an abnormal humoral immune response to a second pathogen, in this case T. pallidum, is discussed. Our case is one of several recent cases of active syphilis reported in individuals with HIV seropositivity.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Radolf JD,Kaplan RPdoi
10.1016/s0190-9622(88)70062-6subject
Has Abstractpub_date
1988-02-01 00:00:00pages
423-8issue
2 Pt 2eissn
0190-9622issn
1097-6787pii
S0190-9622(88)70062-6journal_volume
18pub_type
杂志文章abstract::Many physicians in the United States and other nonendemic countries lack familiarity with New World cutaneous leishmaniasis (CL) and fail to include it in their differential diagnosis when seeing patients with suggestive lesions and recent high-risk travel. Moreover, even when the diagnosis of New World CL is consider...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2009.08.045
更新日期:2011-03-01 00:00:00
abstract::A 38-year-old woman came for treatment of multiple clear vesicles and hemorrhagic papules on the posterior aspect of the right shoulder and the right axillary vault of 5 years' duration. These lesions would spontaneously manifest as clear or blood-filled vesicles (or both) and appear to be exacerbated by physical cont...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2005.04.086
更新日期:2005-09-01 00:00:00
abstract::At the International Consensus Conference for Cutaneous T-Cell Lymphoma (CTCL) Treatment Recommendations (held in Boston, Massachusetts, Oct. 1 and 2, 1994), international experts were asked to assess where consensus existed and to identify areas that required clinical research. We review the epidemiology, pathology, ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 共识发展会议,杂志文章,评审
doi:10.1016/s0190-9622(97)80226-5
更新日期:1997-03-01 00:00:00
abstract::Intravascular lymphomatosis (IVL) is a rare type of lymphoma with a poor prognosis. Its distinctive clinical and histopathologic features are generated by the proliferation of neoplastic mononuclear cells within blood vessels. We describe a patient with IVL of the skin as a manifestation of a recurrent diffuse large B...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2003.112
更新日期:2003-02-01 00:00:00
abstract::A single application (16 to 20 hours) of 1% gamma benzene hexachloride (GBH) lotion, when applied to a total island population of 178 persons in which seventy-four clinically had scabies, resulted in a cure rate of over 98%. Re-examination of the population at 10 and 21 weeks revealed only one remaining individual sti...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(83)70167-2
更新日期:1983-10-01 00:00:00
abstract::The Publisher regrets that this article is an accidental duplication of an article that has already been published in J Am Acad Dermatol, 80 (2019) 607 - 607, https://doi.org/10.1016/j.jaad.2018.10.049. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at h...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,撤回出版物
doi:10.1016/j.jaad.2018.11.005
更新日期:2019-05-01 00:00:00
abstract::Oral juvenile xanthogranuloma is a rare condition, with only 10 histologically proven cases previously described. A histologically unusual variant is reported here, diagnosis of which was aided by the use of immunohistochemical stains. Previously reported cases are reviewed, and their characteristics are tabulated and...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(95)91438-2
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:Surgical procedures used to remove genital warts (cryotherapy, electrodesiccation) are painful. Attempts to reduce the discomfort of surgery by prior lidocaine infiltration anesthesia are compromised by the pain of the infiltration. OBJECTIVE:Our purpose was to determine the efficacy of topically applied li...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0190-9622(97)70218-4
更新日期:1997-07-01 00:00:00
abstract::Scabies is an ectoparasitic dermatosis caused by Sarcoptes scabiei var. hominis and is a public health issue in all countries regardless of socioeconomic status. In high-income countries, delays in diagnosis can lead to institutional outbreaks; in low- and middle-income countries, poor access to health care contribute...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2019.05.109
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:In 1982 we reported our preliminary observations on the use of home UV phototherapy for patch and early plaque phase mycosis fungoides (MF). OBJECTIVE:Our purpose was to present follow-up data of the original 31 patients, covering an interval of up to 15 years. METHODS:All patients used a commercially avai...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70155-m
更新日期:1993-07-01 00:00:00
abstract::An intensely pruritic dermatosis that occurred in a woman during the third trimester of pregnancy is described. The clinical manifestations included red follicular papules symmetrically distributed on the skin of the forearms, abdomen, thighs, and legs. The histopathologic findings were not specific. However, immunopa...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(88)70059-6
更新日期:1988-02-01 00:00:00
abstract::Clinical trials are critical for the development of new therapies in dermatology, and their results help determine US Food and Drug Administration (FDA) approval and guide care. Of special relevance is the clinical trial efficacy end point, the metric from which statistically significant outcome is derived. Clinicians...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2016.01.052
更新日期:2016-07-01 00:00:00
abstract::The most common active ingredient in hair coloring is para-phenylenediamine (PPDA), which can produce contact dermatitis, particularly in persons who dye their scalp hair and in hairdressers. We have identified another group of patients also at risk, namely men from Arab countries, who commonly grow beards and dye the...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2001.113444
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Oral corticosteroid pulse therapy has provided inconsistent results in the treatment of Indian patients with vitiligo. OBJECTIVE:We wanted to evaluate the efficacy, safety, and tolerability of oral dexamethasone pulse therapy in a cohort of Austrian patients with vitiligo. METHODS:Twenty-nine patients with...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2001.113475
更新日期:2001-05-01 00:00:00
abstract:BACKGROUND:Unwanted tattoos are treated with Q-switched lasers. Despite a series of treatments, efficacy is limited. OBJECTIVE:We compared a single Q-switched laser treatment pass with 4 treatment passes separated by 20 minutes. METHODS:Eighteen tattoos on 12 adults were divided in half and randomized. One half recei...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2011.07.024
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Malignant melanomas occur with increased frequency and at an early age in patients with xeroderma pigmentosum (XP). OBJECTIVE:The purpose of this study was to describe the histologic features of malignant melanomas in patients with XP and to search for a possible precursor lesion. METHODS:Clinical records ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70079-9
更新日期:1993-04-01 00:00:00
abstract::A survey of dermatologic training centers in the United States and Canada discloses that only 12% use conventional x-ray therapy intramurally and an additional 15% utilize grenz ray therapy. Although many refer patients to radiologists on a regular basis, half of the present training programs consider radiation therap...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(86)70134-5
更新日期:1986-06-01 00:00:00
abstract::The etiology of mycosis fungoides (MF) is uncertain, although infectious agents and other environmental exposures have been implicated. We describe what appears to be the first case in which both a husband and his wife were diagnosed with large-cell transformation of MF. After 10 years of having stage I MF, the wife d...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2005.09.013
更新日期:2006-05-01 00:00:00
abstract::Arthropod bites remain a major cause of patient morbidity. These bites can cause local or systemic effects that may be infectious or inflammatory in nature. Arthropods, notably insects and arachnids, are vectors of potentially serious ailments including malaria, West Nile virus, dengue, and Lyme disease. Measures to c...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2007.10.005
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Sox10 is a transcription factor associated with neural crest development. Its expression has been reported in melanocytes and peripheral nerve sheath cells and their associated tumors. OBJECTIVE:To assess Sox10 sensitivity in benign and malignant melanocytic neoplasms of various histologic subtypes and to d...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2011.12.035
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:BRAF mutations occur in some melanomas. We hypothesized that BRAF mutation rates may differ in melanomas found in Asian compared to white populations. OBJECTIVE:We performed a metaanalysis of BRAF mutations and their associations with the clinicopathologic characteristics of primary melanoma (PM), with a su...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jaad.2015.02.1113
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Early recognition of melanoma is the key in preventing metastatic disease. OBJECTIVE:The aim of this study was to evaluate diagnostic ability of general practitioners (GPs) and dermatologists concerning pigmented skin lesions in general and melanoma in particular. We also investigated whether the diagnostic...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2001.113442
更新日期:2001-06-01 00:00:00
abstract::Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should i...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(81)70053-7
更新日期:1981-05-01 00:00:00
abstract::The deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a pigmented lesion that commonly arises on the head and neck in the first few decades of life. Histopathologically, the DPN is wedge-shaped and contains melanocytes that exhibit deep infiltration into the dermis. Given these features,...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2014.07.026
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:The evidence of hairs grouped into well-defined follicular units has given a new vision of hair anatomy and pathology. The sebaceous glands and the arrector pili muscle, as part of the pilosebaceous unit, should be viewed as important parts of this organized follicular unit structure. OBJECTIVE:This study w...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2004.01.054
更新日期:2004-08-01 00:00:00
abstract::Costs for dermatitis can be evaluated against the costs and potential benefits of patch testing on the basis of data available from several sources. Consideration of cost for an individual patient suggests that costs become neutral and benefits become positive if the dermatitis is persistent and multiple physician vis...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(89)70274-7
更新日期:1989-10-01 00:00:00
abstract:BACKGROUND:Klippel-Trenaunay syndrome (KTS) is a vascular malformation overgrowth syndrome characterized by capillary malformation, venous malformation, and limb overgrowth, with or without lymphatic malformation. Patients are at an increased risk of hemorrhage and venous thromboembolism (VTE). Consequently, women with...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2019.04.018
更新日期:2019-12-01 00:00:00
abstract::We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(89)70098-0
更新日期:1989-05-01 00:00:00
abstract::Human immunodeficiency virus (HIV) infection in children has emerged as a major, rapidly growing public health problem. The majority of children become infected by perinatal transmission of the virus from an infected mother. The disease is frequently associated with progressive neurologic dysfunction and with opportun...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(90)70167-g
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Recent studies suggest that ultraviolet (UV) A1 phototherapy is an effective treatment for localized scleroderma (LS); however, the optimum UVA1 dose remains to be determined. OBJECTIVE:We sought to compare the immediate and long-term efficacy of low- versus medium-dose UVA1 phototherapy for plaque-type LS....
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2008.12.013
更新日期:2009-05-01 00:00:00