Proceedings of the International Consensus Conference on Cutaneous T-cell Lymphoma (CTCL) Treatment Recommendations. Boston, Massachusetts, Oct. 1 and 2, 1994.

abstract：:Clinical trials for systemic psoriasis therapy typically enroll healthy patients and exclude patients with cardiovascular disease, latent tuberculosis, liver disease, histories of malignancies, viral infections, children, and pregnant or breast-feeding women. Physicians often require guidance for optimum management of...

journal_title：Journal of the American Academy of Dermatology

authors： Strober B,Berger E,Cather J,Cohen D,Crowley JJ,Gordon KB,Gottlieb A,Horn EJ,Kavanaugh AF,Korman NJ,Krueger GG,Leonardi CL,Menter A,Schwartzman S,Sobell JM,Young M

更新日期：2009-07-01 00:00:00

abstract：:The effect of drug concentrations of 2.5%, 5%, and 10% upon the transepidermal penetration of 14C-benzoyl peroxide in a lotion vehicle was assessed in excised human skin and in vivo in the rhesus monkey. In vitro, penetration of benzoyl peroxide was concentration-dependent, both as to rate and to amount, as measured b...

journal_title：Journal of the American Academy of Dermatology

authors： Yeung D,Nacht S,Bucks D,Maibach HI

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Connective tissue nevi (CTN) may be isolated, either sporadic or hereditary, or syndromic as in the Buschke-Ollendorff syndrome. Few publications have addressed the variable clinical and histopathologic expression of these benign hamartomas. OBJECTIVE:We sought to characterize the clinical and histopatholog...

journal_title：Journal of the American Academy of Dermatology

authors： Saussine A,Marrou K,Delanoé P,Bodak N,Hamel D,Picard A,Sassolas B,de Prost Y,Lemerrer M,Fraitag S,Bodemer C

更新日期：2012-08-01 00:00:00

abstract：:Adult T-cell leukemia/lymphoma (ATLL) often involves the skin. Cases with skin lesions without either leukemic nor lymph node involvement have been categorized into a cutaneous type. While the clinical manifestations of the cutaneous-type ATLL are variable, including multiple papules, nodules, plaques, or erythroderma...

journal_title：Journal of the American Academy of Dermatology

authors： Shimizu S,Yasui C,Koizumi K,Ikeda H,Tsuchiya K

更新日期：2007-11-01 00:00:00

abstract：:We describe four patients who developed basal cell carcinoma (BCC) among multiple facial trichoepitheliomas. The only clinical feature that distinguished the carcinomas from the trichoepitheliomas was their larger size in three of the four patients. None of the lesions ulcerated. Whether the BCCs developed independent...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson SC,Bennett RG

更新日期：1993-02-01 00:00:00

abstract：:Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome. Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclear anomalies, that is, hyposegmentation (pseudo-Pelger-Huët anomaly) or hypersegmentation. Peripheral blood and bone marrow neutrophils had similar...

journal_title：Journal of the American Academy of Dermatology

authors： Morioka N,Otsuka F,Nogita T,Igisu K,Urabe A,Ishibashi Y

更新日期：1990-08-01 00:00:00

abstract：:A case of porphyria cutanea tarda in a human immunodeficiency virus-infected patient with hemophilia is reported. Onset of skin manifestations of porphyria cutanea tarda coincided with deterioration of immune function. However, acquired immunodeficiency syndrome has not yet developed with a follow-up interval of 39 mo...

journal_title：Journal of the American Academy of Dermatology

authors： Conlan MG,Hoots WK

更新日期：1992-05-01 00:00:00

abstract：:We describe a 4-year-old, otherwise healthy boy with a congenital history of a perioral and labial segmental café-au-lait macule, who was noted to have unilateral localized gingival hyperpigmentation that aligned with the café-au-lait macule. This case is highly illustrative of the embryologic timing of the genetic ev...

journal_title：Journal of the American Academy of Dermatology

authors： Sergay A,Silverberg NB

更新日期：2007-05-01 00:00:00

abstract：:Angioedema is characterized by localized swelling of sudden onset affecting the skin and/or mucous membranes. It can be classified into hereditary and acquired forms. Hereditary angioedema is a rare disease inherited as an autosomal dominant trait and caused by a deficiency of C1-esterase inhibitor. Acute attacks are ...

journal_title：Journal of the American Academy of Dermatology

authors： Greaves M,Lawlor F

更新日期：1991-07-01 00:00:00

abstract：:Fifteen children who had foot dermatitis were evaluated by examinations with potassium hydroxide and fungal cultures. In eight cases dermatophyte infection was identified. Tinea pedis in prepubertal children is more common than previously reported. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kearse HL,Miller OF 3rd

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Treatment guidelines are lacking for classic Kaposi sarcoma. OBJECTIVE:We sought to review the evidence on efficacy of treatments for classic Kaposi sarcoma. METHODS:Articles published in English or French in MEDLINE, Trip, Cochrane Library, and Pascal databases from 1980 to December 2010 were screened. St...

journal_title：Journal of the American Academy of Dermatology

authors： Régnier-Rosencher E,Guillot B,Dupin N

更新日期：2013-02-01 00:00:00

abstract：:Low dose methotrexate (MTX) can cause numerous gastrointestinal, pulmonary, central nervous system, and hematologic toxicities. Risk factors include folate deficiency, decreased renal function, older age, increased mean corpuscular volume or concomitant use of trimethoprim-sulphamethoxazole, probenecid, or nonsteroida...

journal_title：Journal of the American Academy of Dermatology

authors： Jih DM,Werth VP

更新日期：1998-08-01 00:00:00

abstract：:Cytodestructive or surgical therapy for patients with anogenital warts is frequently associated with recurrence. In February 1997, the US Food and Drug Administration approved imiquimod as a 5% cream for the treatment of anogenital warts. Activity of the drug results primarily from interferon alfa and other cytokine i...

journal_title：Journal of the American Academy of Dermatology

authors： Carrasco D,vander Straten M,Tyring SK

更新日期：2002-10-01 00:00:00

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:In primary melanomas, data on the degree of intratumoral heterogeneity to date have been lacking. OBJECTIVE:Our purpose was to investigate intratumoral DNA stem-line heterogeneity in superficial spreading melanoma (SSM). METHODS:Multiple measuring fields of 54 SSMs (tumor thickness median 1.60 mm) were stu...

journal_title：Journal of the American Academy of Dermatology

authors： Helmbold P,Altrichter D,Klapperstück T,Marsch WCh

更新日期：2005-05-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:Pigmentary demarcation lines are borders of abrupt transition between more deeply pigmented skin and that of lighter pigmentation. Two patients developed these lines on the lower extremities during pregnancy. ...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Meltzer MS,Guill MA,Berger TG,Rodman OG

更新日期：1984-09-01 00:00:00

abstract：:A 16-year-old male patient had multiple angiokeratotic lesions arranged in a linear pattern on his left arm. Histopathologic examination showed characteristic features of verrucous hemangioma. This entity should be distinguished from angiokeratoma or simple hemangioma. The linear arrangement of lesions as observed in ...

journal_title：Journal of the American Academy of Dermatology

authors： Wentscher U,Happle R

更新日期：2000-03-01 00:00:00

abstract：:Nail apparatus melanoma (or subungual melanoma) is rare and accounts for only 1.4% of all cutaneous melanomas in the United Kingdom. We report the use of fixed-tissue Mohs micrographic surgery to treat a biopsy-proven Clark level I in situ nail apparatus melanoma, presenting with diffuse longitudinal melanonychia. ...

journal_title：Journal of the American Academy of Dermatology

authors： Banfield CC,Dawber RP,Walker NP,Stables GI,Zeina B,Schomberg K

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The difficulties in accurately assessing pigmented skin lesions are ever present in practice. The recently described ABCD rule of dermatoscopy (skin surface microscopy at x10 magnification), based on the criteria asymmetry (A), border (B), color (C), and differential structure (D), improved diagnostic accura...

journal_title：Journal of the American Academy of Dermatology

authors： Nachbar F,Stolz W,Merkle T,Cognetta AB,Vogt T,Landthaler M,Bilek P,Braun-Falco O,Plewig G

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. OBJECTIVE:To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. METHODS:...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA,Whiting DA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The formulation of topical dermatologic products must take into account efficacy, safety, and patient compliance. OBJECTIVE:We describe how an aqueous gel containing adapalene, a novel naphthoic acid derivative was selected for the topical treatment of acne. METHODS AND RESULTS:Dose selection was made usin...

journal_title：Journal of the American Academy of Dermatology

authors： Allec J,Chatelus A,Wagner N

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:The possible association of silicone breast implants and disease is a subject of continuous debate and concern. OBJECTIVE:Our purpose was to examine microscopically and ultrastructurally the periprosthetic fibrous capsules and reconstruction scars of women with silicone breast implants. METHODS:Representat...

journal_title：Journal of the American Academy of Dermatology

authors： Raso DS,Greene WB,Harley RA,Maize JC

更新日期：1996-07-01 00:00:00

abstract：:Epidermolysis bullosa acquisita is a chronic, severe, subepidermal, blistering disease of the skin, characterized by marked resistance to topical and systemic therapy. This report concerns a well-documented case of a woman who had had epidermolysis bullosa acquisita for 6 years and had remained hospitalized continuous...

journal_title：Journal of the American Academy of Dermatology

authors： Crow LL,Finkle JP,Gammon WR,Woodley DT

更新日期：1988-11-01 00:00:00

abstract：:A 65-year-old man with insulin-dependent diabetes developed intractable pruritus preceding weight loss and increasing fatiguability. Esophagogastroduodenoscopy revealed infection with Candida, cytomegalovirus, and Cryptosporidium. His T cell helper/suppressor ratio was inverted, and the serum human immunodeficiency vi...

journal_title：Journal of the American Academy of Dermatology

authors： Shapiro RS,Samorodin C,Hood AF

更新日期：1987-05-01 00:00:00

abstract：:Pyoderma gangrenosum (PG) has four distinctive clinical and histologic variants. Some have morphologic and histologic overlapping features with other reactive neutrophilic skin conditions. PG often occurs in association with a systemic disease, and the specific clinical features of the skin lesion may provide a clue t...

journal_title：Journal of the American Academy of Dermatology

authors： Powell FC,Su WP,Perry HO

更新日期：1996-03-01 00:00:00

abstract：:Multiple studies have shown that dermoscopy increases the sensitivity and specificity for the detection of skin cancers compared with examination by the naked eye. Dermoscopy can also lead to the detection of thinner and smaller cancers. In addition, dermoscopy leads to the more precise selection of lesions requiring ...

journal_title：Journal of the American Academy of Dermatology

authors： Yélamos O,Braun RP,Liopyris K,Wolner ZJ,Kerl K,Gerami P,Marghoob AA

更新日期：2019-02-01 00:00:00

abstract：:Hyperkeratosis of the nipple and areola is a rare condition. We report two cases of hyperkeratosis of the nipple and areola occurring in men with no underlying endocrinopathy or synthetic estrogenic drug therapy. Both patients demonstrated prompt resolution of the hyperkeratosis of the nipples with a keratolytic gel. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhlman DS,Hodge SJ,Owen LG

更新日期：1985-10-01 00:00:00

abstract：:Cultured epidermal sheets were examined before and at various times after grafting on skin ulcer beds. Before grafting, the sheet consisted of four to five layers of keratinocytes with incomplete differentiation. Ten days after grafting, graft recipient sites showed compact hyperkeratosis, a normal-appearing epidermis...

journal_title：Journal of the American Academy of Dermatology

authors： Phillips TJ,Bhawan J,Leigh IM,Baum HJ,Gilchrest BA

更新日期：1990-08-01 00:00:00