The deep penetrating nevus.

abstract：BACKGROUND:Actinic keratosis is a skin lesion that can progress to squamous cell carcinoma but cannot always be clinically distinguished from a squamous cell carcinoma. OBJECTIVE:The purpose of this article is to describe the clinical presentation of actinic keratoses and squamous cell carcinoma. METHODS:The author's...

journal_title：Journal of the American Academy of Dermatology

authors： Moy RL

更新日期：2000-01-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：:The advent of electron microscopy and immunohistochemical stains allowed for reclassification of the histiocytoses based on the predominant cell in the infiltrate. Although the current schema simplicity provides a good foundation, some patients display overlapping clinical and immunohistochemical features that defy cl...

journal_title：Journal of the American Academy of Dermatology

authors： Satter EK,Gendernalik SB,Galeckas KJ

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Safe and efficacious topical treatments are needed for atopic dermatitis (AD). OBJECTIVE:We assessed the safety and efficacy of tapinarof cream (2 concentrations and 2 application frequencies) in patients with AD. METHODS:A double-blind, vehicle-controlled, randomized, 6-arm trial (1:1:1:1:1:1) in patients...

journal_title：Journal of the American Academy of Dermatology

authors： Peppers J,Paller AS,Maeda-Chubachi T,Wu S,Robbins K,Gallagher K,Kraus JE

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Inability of topical medications to penetrate via nail plate brings a great challenge to clinicians in treating onychomycosis. Furthermore, oral medications are not appropriate for all patients because of drug interactions, adverse effects, and contraindications. OBJECTIVE:We sought to evaluate the clinical...

journal_title：Journal of the American Academy of Dermatology

authors： Bhatta AK,Keyal U,Huang X,Zhao JJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The development of autoimmune sequelae is one of the characteristic features of drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome; however, the incidence of sequelae and prognosis of patients with DRESS are unknown. OBJECTIVE:We sought to investigate the...

journal_title：Journal of the American Academy of Dermatology

authors： Chen YC,Chang CY,Cho YT,Chiu HC,Chu CY

更新日期：2013-03-01 00:00:00

abstract：:A 1 U/ml solution of bleomycin sulfate in physiologic saline solution was injected intralesionally in 38 patients, and was compared with physiologic saline solution injection into paired warts in the same patient. No patient received more than 2 ml of bleomycin. Ninety-seven of 143 warts (67.8%) showed complete resolu...

journal_title：Journal of the American Academy of Dermatology

authors： Amer M,Diab N,Ramadan A,Galal A,Salem A

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:There is lack of studies on the diagnostic accuracy of dermatoscopy and reflectance confocal microscopy (RCM) for dark pigmented lesions. OBJECTIVE:To assess the diagnostic accuracy of dermatoscopy plus confocal microscopy for melanoma diagnosis of dark pigmented lesions in real life. METHODS:Prospective a...

journal_title：Journal of the American Academy of Dermatology

authors： Longo C,Mazzeo M,Raucci M,Cornacchia L,Lai M,Bianchi L,Peris K,Pampena R,Pellacani G

更新日期：2020-07-27 00:00:00

abstract：:A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez MR,Ross B,Rotterdam H,Salik J,Brodie R,Freedberg IM

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Butenafine hydrochloride, a benzylamine derivative with potent antifungal activity, has been used in Japan to treat superficial fungal diseases. OBJECTIVE:We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomiz...

journal_title：Journal of the American Academy of Dermatology

authors： Savin R,De Villez RL,Elewski B,Hong S,Jones T,Lowe N,Lucky A,Reyes B,Stewart D,Willis I

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature. OBJECTIVE:To provide up-to-date information regarding the state of teledermatology programs in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Wu J,Kovarik CL,Goldyne ME,Oh DH,McKoy KC,Shippy AM,Pak HS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Whole-body imaging is the current standard of care for staging all patients presenting with skin lesions of B-cell lymphomas (BCLs), regardless of skin disease extent; however, supporting data are lacking. OBJECTIVE:To determine the clinical utility of imaging in the detection of systemic involvement in low...

journal_title：Journal of the American Academy of Dermatology

authors： Kheterpal MK,Dai J,Geller S,Pulitzer M,Ni A,Myskowski PL,Moskowitz A,Kim J,Hong EK,Fong S,Hoppe RT,Kim YH,Horwitz SM

更新日期：2019-10-01 00:00:00

abstract：:It has long been observed that sun exposure can induce or exacerbate skin lesions in patients with certain forms of lupus erythematosus. Despite the frequency of photosensitivity in these patients, the mechanism by which ultraviolet radiation alters the pathogenic course of this disease remains poorly understood. Afte...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhn A,Sonntag M,Richter-Hintz D,Oslislo C,Megahed M,Ruzicka T,Lehmann P

更新日期：2001-07-01 00:00:00

abstract：:Chemotherapy-induced alopecia is a distressing side effect common to certain treatment regimens in oncology. Unfortunately, chemotherapy-induced alopecia is an often overlooked or minor factor among our current research priorities and thus advances in amelioration have been minimal. This review offers a comprehensive ...

journal_title：Journal of the American Academy of Dermatology

authors： Chon SY,Champion RW,Geddes ER,Rashid RM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Although a variety of ablative, topical, and systemic therapies are used for molluscum contagiosum (MC), none has been well studied or approved by the US Food and Drug Administration. OBJECTIVES:To compare the efficacy and tolerability of topical SB206 (berdazimer sodium gel coadministered with hydrogel) wi...

journal_title：Journal of the American Academy of Dermatology

authors： Hebert AA,Siegfried EC,Durham T,de León EN,Reams T,Messersmith E,Maeda-Chubachi T

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The concept of contact allergy aggravating or inducing oral lichenoid mucositis diagnosed as oral lichen planus (OLP) is well recognized but somewhat controversial. OBJECTIVE:We sought to identify clinically relevant contact allergens that may be important in the management of patients with OLP. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Yiannias JA,el-Azhary RA,Hand JH,Pakzad SY,Rogers RS 3rd

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:A discrimination between benign and malignant melanocytic lesions is not always possible by conventional histology. OBJECTIVE:Our purpose was to determine the proliferative activity in various types of melanocytic neoplasms and to appraise its value as a diagnostic adjunct. METHODS:The growth fraction was ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph P,Schubert C,Schubert B,Parwaresch R

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Pachyonychia congenita (PC) is a group of autosomal dominant keratinizing disorders caused by a mutation in one of 4 keratin genes. Previous classification schemes have relied on data from case series and case reports. Most patients in these reports were not genetically tested for PC. OBJECTIVE:We sought to...

journal_title：Journal of the American Academy of Dermatology

authors： Eliason MJ,Leachman SA,Feng BJ,Schwartz ME,Hansen CD

更新日期：2012-10-01 00:00:00

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：:The presence of immunoglobulin and complement deposits in the skin of three patients with papular urticaria suggests that these lesions may be due to a cutaneous vasculitis. These deposits were most frequently found in biopsy specimens taken from lesions within 24 hours of their development. The presence of granular d...

journal_title：Journal of the American Academy of Dermatology

authors： Heng MC,Kloss SG,Haberfelde GC

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:There is controversy regarding a potential increased risk of lymphoma in patients with atopic dermatitis (AD). OBJECTIVE:To assess the risk of lymphoma and the role of topical treatments in patients with AD. METHODS:A systematic literature search and a separate meta-analysis were performed on case control ...

journal_title：Journal of the American Academy of Dermatology

authors： Legendre L,Barnetche T,Mazereeuw-Hautier J,Meyer N,Murrell D,Paul C

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Incomplete Mohs micrographic surgery (MMS) is the cessation of MMS while the tumor margins are known to be still positive. OBJECTIVE:Our purpose was to examine the factors behind unplanned incomplete MMS and to identify means of avoiding and managing this situation when it arises. METHODS:We performed a re...

journal_title：Journal of the American Academy of Dermatology

authors： Madani S,Huilgol SC,Carruthers A

更新日期：2000-05-01 00:00:00

abstract：:Botryomycosis in an uncommon chronic bacterial infection that mimics fungal disease clinically and histologically. Microscopically the hallmark of the disease is the presence of fungus-like granules in which the causative organism is embedded. A patient with typical cutaneous botryomycosis is presented, along with the...

journal_title：Journal of the American Academy of Dermatology

authors： Brunken RC,Lichon-Chao N,van der Broek H

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:The administration of a local anesthetic is often painful. OBJECTIVE:The purpose of this study was to determine whether rapidly shaking and pinching the skin during local anesthetic administration decreases pain perception. METHODS:The skin at the intended site of lidocaine injection was rapidly pinched be...

journal_title：Journal of the American Academy of Dermatology

authors： Fosko SW,Gibney MD,Harrison B

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Pigmented Spitz nevi have distinct clinical features but often may be difficult to differentiate from malignant melanoma by clinical criteria. OBJECTIVE:The purpose of this study was to use a new noninvasive diagnostic approach to improve the clinical diagnosis of Spitz nevi. METHODS:Epiluminescence micros...

journal_title：Journal of the American Academy of Dermatology

authors： Steiner A,Pehamberger H,Binder M,Wolff K

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The hazards of acute radiation exposure are well known. Bone marrow failure from total body gamma or neutron irradiation is the most clinically relevant aspect of acute radiation disease. With nonhomogeneous exposure, as is characteristic in accidents, other organ systems, such as the skin, may be more impor...

journal_title：Journal of the American Academy of Dermatology

authors： Peter RU,Braun-Falco O,Birioukov A,Hacker N,Kerscher M,Peterseim U,Ruzicka T,Konz B,Plewig G

更新日期：1994-05-01 00:00:00

abstract：:A 56-year-old man had a deeply invasive leiomyosarcoma of the right buttock. Leiomyosarcomas of the skin and subcutaneous tissues are rare, and most occur on the extremities. Wide local excision is the therapy of choice. ...

journal_title：Journal of the American Academy of Dermatology

authors： Landry MM,Sarma DP,Boucree JB Jr

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed. OBJECTIVE:We attempted to evaluate the effectiveness of oral minocycline. METHODS:Nine patients with CRP were treated with oral minocycline,...

journal_title：Journal of the American Academy of Dermatology

authors： Montemarano AD,Hengge M,Sau P,Welch M

更新日期：1996-02-01 00:00:00

abstract：:Onycholysis (ONY) of the fingernails is a common disorder that is diagnosed with ease but often managed with great difficulty. The full spectrum of causes is broad and not always readily apparent. In this review, an approach to the evaluation and management of ONY is offered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kechijian P

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:UVA induces tissue damage via the production of radical oxygen species. Adding antioxidants to UV filters in sunscreens is a novel photoprotective strategy. The topical application of antioxidants in sunscreen can potentially neutralize the UVA-induced free radicals. OBJECTIVES:We sought to assess the degre...

journal_title：Journal of the American Academy of Dermatology

authors： Wang SQ,Osterwalder U,Jung K

更新日期：2011-09-01 00:00:00