Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: A systematic review and meta-analysis.

abstract：:We report two cases of mycosis fungoides with marked, pleomorphic follicular manifestations. Follicular hyperkeratosis, comedo-like lesions, acquired epidermal cysts, and patchy alopecia developed in various locations in both patients. Findings of histopathologic and immunohistochemical studies showed atypical CD4+ T ...

journal_title：Journal of the American Academy of Dermatology

authors： Lacour JP,Castanet J,Perrin C,Ortonne JP

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Psoriasiform dermatitis is common in patients with AIDS. The expression of heat shock proteins by keratinocytes has been postulated to be a significant factor in the physiopathology of psoriasis and might be subject to modulation in HIV-infected patients. OBJECTIVE:We sought to evaluate the epidermal expres...

journal_title：Journal of the American Academy of Dermatology

authors： Puig L,Fernández-Figueras MT,Ferrándiz C,Ribera M,de Moragas JM

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

journal_title：Journal of the American Academy of Dermatology

authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Effective medical treatment for patients with severe hidradenitis suppurativa (HS) is limited. OBJECTIVES:We sought to measure the impact of wide local excision on quality of life in HS Hurley grade III patients and to examine the rate of postoperative complications, disease recurrences, and satisfaction wi...

journal_title：Journal of the American Academy of Dermatology

authors： Posch C,Monshi B,Quint T,Vujic I,Lilgenau N,Rappersberger K

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with psoriasis have been reported. OBJECTIVES:To assess the prevalence and incidence of PsA in patients with psoriasis. METHODS:Two authors independently searched 3 databases for studies reporting on the prevalence or incidence of P...

journal_title：Journal of the American Academy of Dermatology

authors： Alinaghi F,Calov M,Kristensen LE,Gladman DD,Coates LC,Jullien D,Gottlieb AB,Gisondi P,Wu JJ,Thyssen JP,Egeberg A

更新日期：2019-01-01 00:00:00

abstract：:We review experimental studies that address age-related changes in cutaneous barrier function and dermal blood vessel function. These differences have important implications in the understanding of age-related changes in the inflammatory process and topical drug delivery systems. ...

journal_title：Journal of the American Academy of Dermatology

authors： Harvell JD,Maibach HI

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:There is a lack of data on outcomes of management of pemphigus in children. OBJECTIVE:We sought to evaluate rituximab treatment in childhood and juvenile pemphigus. METHOD:All cases of pemphigus treated with rituximab in patients younger than 18 years were included. Clinical and epidemiologic data and deta...

journal_title：Journal of the American Academy of Dermatology

authors： Vinay K,Kanwar AJ,Sawatkar GU,Dogra S,Ishii N,Hashimoto T

更新日期：2014-10-01 00:00:00

abstract：:Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome. Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclear anomalies, that is, hyposegmentation (pseudo-Pelger-Huët anomaly) or hypersegmentation. Peripheral blood and bone marrow neutrophils had similar...

journal_title：Journal of the American Academy of Dermatology

authors： Morioka N,Otsuka F,Nogita T,Igisu K,Urabe A,Ishibashi Y

更新日期：1990-08-01 00:00:00

abstract：:Infantile acropustulosis (IA) is a syndrome characterized by recurrent crops of 1- to 2-mm intensely pruritic vesicopustules that are found primarily on the distal extremities of infants. It is reportedly responsive to sulfones and unresponsive to other therapy, but if left untreated spontaneously resolves at about 2 ...

journal_title：Journal of the American Academy of Dermatology

authors： Jennings JL,Burrows WM

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Genetic and environmental risk factors have been associated with the development of multiple primary melanomas (MPM). We hypothesized that individuals with MPM may have increased predisposition to developing internal malignancies. OBJECTIVE:To identify the risk of subsequent malignancies in MPM patients. M...

journal_title：Journal of the American Academy of Dermatology

authors： Cai ED,Swetter SM,Sarin KY

更新日期：2018-10-01 00:00:00

abstract：:We report eight patients with ulcerative colitis who have subsequently developed pemphigoid. Four patients were investigated to determine the pattern of pemphigoid antibody staining on whole and chemically split skin and oral mucosa to distinguish between pemphigoid and epidermolysis bullosa acquisita. The findings we...

journal_title：Journal of the American Academy of Dermatology

authors： Barth JH,Kelly SE,Wojnarowska F,Savin JA,Whittaker S,Cream JJ,White JE

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Epidermal necrolysis (EN) involving ≥10% of the body surface area (BSA) is often complicated by bacterial infections. OBJECTIVE:We sought to describe the epidemiology of bloodstream infections (BSIs) in EN involving a BSA ≥10% and the diagnostic performances of skin cultures for predicting the pathogen(s) i...

journal_title：Journal of the American Academy of Dermatology

authors： Lecadet A,Woerther PL,Hua C,Colin A,Gomart C,Decousser JW,Mekontso Dessap A,Wolkenstein P,Chosidow O,de Prost N,Ingen-Housz-Oro S

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Severe atopic dermatitis (AD) is increasingly treated with systemic immuno-modulatory drugs yet their safety is unclear. OBJECTIVE:We evaluated the comparative risk of serious bacterial and opportunistic infections among users of systemic immuno-modulatory medications in patients with severe AD in routine c...

journal_title：Journal of the American Academy of Dermatology

authors： Schneeweiss MC,Perez-Chada L,Merola JF

更新日期：2019-05-31 00:00:00

abstract：:A boy with epidermolytic hyperkeratosis was treated systemically for 4 1/2 years with 13-cis-retinoic acid. At the age of 10 1/2 years, he developed pain in his right knee and radiographic evidence of partial closure of the proximal epiphysis of the right tibia. Similar radiographic changes have been described in indi...

journal_title：Journal of the American Academy of Dermatology

authors： Milstone LM,McGuire J,Ablow RC

更新日期：1982-11-01 00:00:00

abstract：:We reviewed all cases of malignant melanoma in children younger than 17 years of age who were evaluated at Sainte Justine Hospital, a tertiary care pediatric center, between 1980 and 2002. The medical records and histologic features of all cases were reviewed. Thirteen cases were identified, 4 boys and 9 girls. Fifty-...

journal_title：Journal of the American Academy of Dermatology

authors： Jafarian F,Powell J,Kokta V,Champagne M,Hatami A,McCuaig C,Marcoux D,Savard P

更新日期：2005-11-01 00:00:00

abstract：:Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

journal_title：Journal of the American Academy of Dermatology

authors： Wester RC,Bucks DA,Maibach HI

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HY,Fook-Chong S,Koh HY,Thirumoorthy T,Pang SM

更新日期：2017-01-01 00:00:00

abstract：:Verruciform xanthomas occur on mucocutaneous surfaces and are characterized by hyperkeratosis, acanthosis, and the occurrence of "foam cells" stuffed with lipid surrounding capillaries in the dermis between rete pegs. Ultrastructural examination of a lesion on the penis revealed the presence of melanocytes with many l...

journal_title：Journal of the American Academy of Dermatology

authors： Balus S,Breathnach AS,O'Grady AJ

更新日期：1991-05-01 00:00:00

abstract：:The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is a rare disorder caused by mutations of the FOXP3 gene. The FOXP3 gene encodes a DNA-binding protein of the forkhead/winged-helix family and is the central controller of the development of CD4+CD25+ regulatory T cells. CD4+CD25+ regu...

journal_title：Journal of the American Academy of Dermatology

authors： McGinness JL,Bivens MM,Greer KE,Patterson JW,Saulsbury FT

更新日期：2006-07-01 00:00:00

abstract：:A 24-year-old woman with autoimmune thrombocytopenia and hypothyroidism had an inflammatory bullous eruption in the mouth, face, and trunk that left no milia or scars after healing. Histologic examination revealed a subepidermal bulla and a neutrophil infiltration. Direct immunofluorescence examination showed depositi...

journal_title：Journal of the American Academy of Dermatology

authors： Taniuchi K,Inaoki M,Nishimura Y,Mori T,Takehara K

更新日期：1997-02-01 00:00:00

abstract：:Five patients are described with the clinical and histopathologic picture, including flame figures, of eosinophilic cellulitis (Wells' syndrome). Two of them had documented tick bites in the center of these expanding annular lesions, and the histologic picture showed the diagnostic flame figures of Wells' syndrome (eo...

journal_title：Journal of the American Academy of Dermatology

authors： Schorr WF,Tauscheck AL,Dickson KB,Melski JW

更新日期：1984-12-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：:Keratosis lichenoides chronica is a rare dermatosis of unknown etiology with a wide variety of cutaneous manifestations. We present a 47-year-old male with a history of progressive and recalcitrant hyperkeratotic and warty plaques, mimicking verrucous secondary syphilis both clinically and microscopically. We review t...

journal_title：Journal of the American Academy of Dermatology

authors： Jayaraman AG,Pomerantz D,Robinson-Bostom L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Dermatitis herpetiformis (DH) is highly associated with celiac disease. Recently, tissue transglutaminase (tTG) was identified as the autoantigen of IgA antibodies in celiac disease. The prevalence of antibodies to tTG in DH patients is not known. OBJECTIVE:The purpose of this study was to determine whether...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Dieterich W,Bröcker EB,Schuppan D,Zillikens D

更新日期：1999-12-01 00:00:00

abstract：:Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic diso...

journal_title：Journal of the American Academy of Dermatology

authors： Williams ML,Packman S,Cowan MJ

更新日期：1983-07-01 00:00:00

abstract：:This review begins with a classification of adverse drug reactions and a summary of those features that distinguish allergic from toxic and idiosyncratic reactions. Factors that influence the risk of developing drug allergy are then reviewed, followed by a discussion of the known and suspected immunologic mechanisms r...

journal_title：Journal of the American Academy of Dermatology

authors： VanArsdel PP Jr

更新日期：1982-05-01 00:00:00

abstract：:Four cases of Laugier-Hunziker syndrome are described. In all patients (two men and two women between 39 and 57 years of age) pigmentation of the lower lip and hard palate was found. in addition, two patients had involvement of the buccal mucosa; another patient also had pigmentation of the upper lip, the gums, the so...

journal_title：Journal of the American Academy of Dermatology

authors： Veraldi S,Cavicchini S,Benelli C,Gasparini G

更新日期：1991-10-01 00:00:00

abstract：:We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone. Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone antibodies. Immunoelectron microscopy demonstrated binding...

journal_title：Journal of the American Academy of Dermatology

authors： Tamada Y,Yokochi K,Nitta Y,Ikeya T,Hara K,Owaribe K

更新日期：1995-05-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor usually involving soft tissue and, in rare cases, the skin. Histologically and biologically it is considered to be a borderline neoplasm between an angiolymphoid hyperplasia with eosinophilia and an epithelioid angiosarcoma. Here we describe an 1...

journal_title：Journal of the American Academy of Dermatology

authors： Forschner A,Harms D,Metzler G,Sönnichsen K,Ulmer A,Rassner G,Fierlbeck G

更新日期：2003-07-01 00:00:00

abstract：:The clinical, electron microscopic, and freeze-fracture features of the skin of a harlequin fetus are described. Ultrastructural findings included large, concentric lamellar bodies, focal absence of intercellular stratum corneum lipid, and an increase in the size of desmosomes and the number of tight junctions. Althou...

journal_title：Journal of the American Academy of Dermatology

authors： Fleck RM,Barnadas M,Schulz WW,Roberts LJ,Freeman RG

更新日期：1989-11-01 00:00:00