Premature epiphyseal closure in a child receiving oral 13-cis-retinoic acid.

Abstract:

:A boy with epidermolytic hyperkeratosis was treated systemically for 4 1/2 years with 13-cis-retinoic acid. At the age of 10 1/2 years, he developed pain in his right knee and radiographic evidence of partial closure of the proximal epiphysis of the right tibia. Similar radiographic changes have been described in individuals ingesting excessive amounts of vitamin A.

journal_name

J Am Acad Dermatol

authors

Milstone LM,McGuire J,Ablow RC

doi

10.1016/s0190-9622(82)70148-3

subject

Has Abstract

pub_date

1982-11-01 00:00:00

pages

663-6

issue

5

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(82)70148-3

journal_volume

7

pub_type

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