Abstract：
:We report a typical case of papular-purpuric "gloves and socks" syndrome (PPGSS) in which primary infection by parvovirus B19 was demonstrated by seroconversion to this virus; parvovirus B19 DNA was also identified by polymerase chain reaction (PCR) methods in the sera of the patient and in the cutaneous biopsy specimen, both taken 4 days after the onset of clinical manifestations. To our knowledge, this is the fourth published case in which parvovirus B19 DNA has been recovered from the skin by PCR. Serologic studies and PCR investigations in cutaneous biopsy for other viruses including herpes simplex virus types 1 and 2, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpesvirus 6, 7, and 8 were negative. Clinically, our case presented some additional features, which have not been previously described in cases of PPGSS, namely dysuria with vulvar edema and erythema, and unilateral petechial rash on the breast. The histopathologic findings of our case were nonspecific and consisted of an interface dermatitis with slight vacuolar degeneration at the dermoepidermal junction and a superficial perivascular inflammatory infiltrate mostly composed of lymphocytes, with numerous extravasated erythrocytes. We review the cases of PPGSS published in the literature with respect to the different viruses that have been proposed as etiologic agents and conclude that acute infection by parvovirus B19 is the only one that has been adequately proved.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Grilli R,Izquierdo MJ,Fariña MC,Kutzner H,Gadea I,Martin L,Requena Ldoi
10.1016/s0190-9622(99)70027-7subject
Has Abstractpub_date
1999-11-01 00:00:00pages
793-6issue
5 Pt 1eissn
0190-9622issn
1097-6787pii
S0190-9622(99)70027-7journal_volume
41pub_type
杂志文章abstract：:A number of dermatologic conditions may have associated esophageal manifestations. Teleologically, this may be because both the skin and the esophagus are lined by stratified squamous epithelium. Bullous dermatoses that may produce blisters, erosions, and/or stricture of the esophagus include cicatricial pemphigoid, H...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(81)70070-7
更新日期：1981-06-01 00:00:00
abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(82)70131-8
更新日期：1982-10-01 00:00:00
abstract：:Sixty-eight cutaneous squamous cell neoplasms (in situ and invasive) and 26 basal cell carcinomas from 89 patients were analyzed for DNA sequences homologous to the human papillomavirus (HPV) types found predominantly in the genital tract. Thirty-six (53%) of the squamous cell neoplasms contained HPV DNA as detected b...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(90)70299-w
更新日期：1990-11-01 00:00:00
abstract：BACKGROUND:The hazards of acute radiation exposure are well known. Bone marrow failure from total body gamma or neutron irradiation is the most clinically relevant aspect of acute radiation disease. With nonhomogeneous exposure, as is characteristic in accidents, other organ systems, such as the skin, may be more impor...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(08)81501-0
更新日期：1994-05-01 00:00:00
abstract：BACKGROUND:This study was undertaken to evaluate the effectiveness and safety of the 577 nm pulsed dye laser in the treatment of various vascular lesions of the face. OBJECTIVE:Our purpose was to make observations on the effects of different variables that could affect response. METHODS:Ninety-two adults with telangi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(92)70174-e
更新日期：1992-08-01 00:00:00
abstract：:Part 3 of this 4-part continuing medical education series reviews several important infectious complications of corticosteroid use, including a focus on pneumocystis pneumonia (PCP) prophylaxis, tuberculosis, viral hepatitis, and other infections, followed by a discussion of vaccination recommendations in immunosuppre...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2016.02.1240
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:Despite the prevalence of androgenetic alopecia among men, little is known about its psychological effects. OBJECTIVE:This investigation examined the psychosocial sequelae that balding men attribute to hair loss and compared balding and nonbalding men in personality functioning. METHODS:Subjects included 6...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(92)70134-2
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:Segmental vitiligo (SV) is characterized by a unilateral and localized distribution, early onset, and stable disease after rapid progression. And SV is often associated with poor response to various treatment modalities. OBJECTIVE:We sought to evaluate the effectiveness of combination therapy with 308-nm ex...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2015.04.008
更新日期：2015-07-01 00:00:00
abstract：:The terminology of the specific dermatoses of pregnancy has become increasingly confusing, with several names in use for identical clinical disorders. On the basis of our own study of sixty-four patients and a review of the literature, we propose a simplified classification: (1) herpes gestationis (pemphigoid gestatio...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(83)70046-0
更新日期：1983-03-01 00:00:00
abstract：BACKGROUND:Safety profiles of systemic biologic agents for the treatment of psoriasis and psoriatic arthritis (PsA) encompass a wide spectrum of adverse events. To date, no uniform evidence-based guidelines exist regarding screening and monitoring patients who are undergoing biologic therapy. OBJECTIVE:We sought to id...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2015.06.004
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:Ipilimumab is a human antibody that inhibits cytotoxic T-lymphocyte-associated antigen 4, leading to increases in T-cell activation and interleukin 2 secretion and has been approved for the treatment of advanced melanoma. Dermatologic adverse events such as rash, pruritus, and vitiligo have been reported in ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jaad.2012.12.963
更新日期：2013-09-01 00:00:00
abstract：:Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. Phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm(2) and increased to a maximum of 1500 mJ/cm(2). All lesions disappeared completely aft...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2004.02.009
更新日期：2004-06-01 00:00:00
abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(89)70094-3
更新日期：1989-05-01 00:00:00
abstract：:Rosacea is a skin condition of abnormal inflammation and vascular dysfunction. The active contribution of a microbial agent in the development or progression of rosacea continues to be debated. Research supports the presence of commensal Demodex folliculorum mites at increased density in the skin and associates Helico...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2013.08.006
更新日期：2013-12-01 00:00:00
abstract：:Twenty-six lymph node biopsy specimens from twenty-three patients with Sézary syndrome were microscopically evaluated and compared with nodal specimens from six patients with pre-Sézary syndrome and four control patients with dermatopathic lymphadenopathy. Three phases of nodal involvement by cerebriform lymphocytes w...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(84)80467-3
更新日期：1984-11-01 00:00:00
abstract：BACKGROUND:Multiple myeloma (MM) is a plasma cell dyscrasia characterized by a clonal proliferation of plasma cells that produces a monoclonal protein. There are dermatologic disorders that have been associated with MM, such as amyloidosis, cryoglobulinemia, POEMS syndrome, normolipemic plane xanthoma, and plasmacytoma...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1067/mjd.2003.180
更新日期：2003-04-01 00:00:00
abstract：:We present further evidence that granuloma annulare and autoimmune thyroiditis may be associated. Only 11 cases have been previously reported with this association as far as we know. It may be advantageous to consider checking the thyroid-stimulating hormone and/or antithyroid antibodies before administering medicatio...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:Crystalline/chrysalis structures (CS) are white shiny streaks that can only be seen with polarized dermatoscopy. OBJECTIVES:We sought to estimate the prevalence and assess the clinical significance of CS in melanocytic and nonmelanocytic lesions. METHODS:This was a prospective observational study in which ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2011.04.039
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:The formulation of topical dermatologic products must take into account efficacy, safety, and patient compliance. OBJECTIVE:We describe how an aqueous gel containing adapalene, a novel naphthoic acid derivative was selected for the topical treatment of acne. METHODS AND RESULTS:Dose selection was made usin...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(97)70055-0
更新日期：1997-06-01 00:00:00
abstract：BACKGROUND:Diet is a modulator of inflammation that might impact inflammatory skin diseases. OBJECTIVE:To assess the relationship between pro-inflammatory dietary patterns and incident psoriasis, psoriatic arthritis (PsA), and atopic dermatitis (AD). METHODS:We conducted cohort studies among women in the Nurses' Heal...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2019.02.038
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Patients with onychomycosis may experience physical impairment and psychological and social limitations related to their infection. OBJECTIVE:The object of this study was to compare health-related quality-of-life scores of patients with onychomycosis with those of a control group. METHODS:The interview ins...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(98)70487-6
更新日期：1998-05-01 00:00:00
abstract：:Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(83)70072-1
更新日期：1983-05-01 00:00:00
abstract：:A 36-year-old man had a high titer of antibody to Epstein-Barr virus (EBV) and recurrent necrotizing papules and nodules on his face and oral mucosa. The disease was diagnosed as CD3+4- 8+ large granular lymphocyte leukemia of T-cell origin. Southern blot analysis demonstrated that EBV DNA was present in CD8+ lymphocy...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(94)70157-1
更新日期：1994-08-01 00:00:00
abstract：BACKGROUND:In the United States, complementary and alternative medicine (CAM) is used for a variety of diseases, including those of the skin. An estimate of the prevalence of CAM use among adults with skin disease using the alternative health supplement of the 2002 National Health Interview Survey (NHIS) has been publi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2009.12.009
更新日期：2010-12-01 00:00:00
abstract：:We describe a 48-year-old woman with a 12-year history of porphyria cutanea tarda who showed a remarkable exacerbation of her eruptions accompanied by high serum levels of iron and ferritin at menopause. As iron storage is known to be a triggering factor of porphyria cutanea tarda, the possible role of menstruation as...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1067/s0190-9622(03)00483-3
更新日期：2003-09-01 00:00:00
abstract：:We reviewed all cases of malignant melanoma in children younger than 17 years of age who were evaluated at Sainte Justine Hospital, a tertiary care pediatric center, between 1980 and 2002. The medical records and histologic features of all cases were reviewed. Thirteen cases were identified, 4 boys and 9 girls. Fifty-...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2005.07.013
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:The epidemiology of pediatric melanoma is distinct from that seen in adults. This is more distinguishable when pediatric patients are separated into prepubertal and adolescent groups. OBJECTIVE:In this study, we compared epidemiologic, clinical, histologic, and molecular characteristics of pediatric superfi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2017.05.051
更新日期：2017-11-01 00:00:00
abstract：:The role of estrogens in the development of skin cancer is controversial. Sex steroids have a profound effect on the epidermis and epidermal appendages. Estradiol in pharmacologic doses has been reported to stimulate basal cell carcinoma in an animal model. Sex hormones act by means of a specific protein receptor. In ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(88)70101-2
更新日期：1988-05-01 00:00:00
abstract：BACKGROUND:The impact of dermatology consultation on the care of children with oncologic conditions is unknown. OBJECTIVE:To review outpatient dermatology visits and the resulting impact on diagnosis and management of pediatric oncology patients. METHOD:Retrospective review of pediatric oncology patients with outpati...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2017.06.005
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis is a common multifactorial disease that seems to be increasing in frequency. OBJECTIVE:Our purpose was to determine the increased prevalence of atopic dermatitis in North Europe. METHODS:Approximately 3000 7-year-old children in Denmark, Germany, and Sweden were enrolled in a cross-sectio...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(96)90009-2
更新日期：1996-05-01 00:00:00
