The specific dermatoses of pregnancy.

abstract：BACKGROUND:Psoriasis is a systemic inflammatory condition that is associated with a higher risk of cardiovascular (CV) disease. Tofacitinib is being investigated as a treatment for psoriasis. OBJECTIVE:We sought to evaluate the effects of tofacitinib on CV risk factors and major adverse CV events (MACEs) in patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Wu JJ,Strober BE,Hansen PR,Ahlehoff O,Egeberg A,Qureshi AA,Robertson D,Valdez H,Tan H,Wolk R

更新日期：2016-11-01 00:00:00

abstract：:Extramedullary hematopoiesis (EMH) is a relatively rare, but well-documented, manifestation of chronic myeloproliferative disorders. Microscopically, foci of EMH consist of erythroid and myeloid precursors intermixed with megakaryocytes. It typically occurs in the spleen and liver, but very occasionally manifests as c...

journal_title：Journal of the American Academy of Dermatology

authors： Kawakami T,Kimura S,Kato M,Mizoguchi M,Soma Y

更新日期：2008-04-01 00:00:00

abstract：:Multiple basal cell epitheliomas developed in two psoriatic patients during treatment with orally administered 8-methoxypsoralen and long-wave ultraviolet radiation (PUVA). Twenty-two basal cell epitheliomas (BCEs) were seen in the two patients, 80% occurring in non-sun-exposed areas. Since neither patient had any his...

journal_title：Journal of the American Academy of Dermatology

authors： Brown FS,Burnett JW,Robinson HM Jr

更新日期：1980-05-01 00:00:00

abstract：:The clinical and histologic features of 26 cases of erythema induratum are reviewed. The characteristic cutaneous lesions on the legs of middle-aged women were violaceous, indurated nodules, 1 to 2 cm in diameter, which were painful, occasionally ulcerated, and could heal with scarring. The diagnosis was confirmed in ...

journal_title：Journal of the American Academy of Dermatology

authors： Rademaker M,Lowe DG,Munro DD

更新日期：1989-10-01 00:00:00

abstract：:The sudden eruption of atypical and benign melanocytic nevi has been associated with a number of disease states and primary skin conditions. Most case reports and series of patients have linked eruptive nevi with blistering skin disease or immunosuppression. Subsets of patients in the immunosuppressed category have re...

journal_title：Journal of the American Academy of Dermatology

authors： Woodhouse J,Maytin EV

更新日期：2005-05-01 00:00:00

abstract：:Our studies of mononuclear leukocyte peripheral blood homogenates demonstrate significantly increased cyclic adenosine monophosphate-specific phosphodiesterase activity in patients with atopic dermatitis who were untreated for 1 week, compared with normal adult nonatopic control subjects. Phosphodiesterase activity is...

journal_title：Journal of the American Academy of Dermatology

authors： Holden CA,Yuen CT

更新日期：1989-07-01 00:00:00

abstract：:To determine whether systemic hydrocortisone can elicit allergic skin reactions in patients with contact hypersensitivity to hydrocortisone, we studied four patients with contact hypersensitivity to hydrocortisone and hydrocortisone-17-butyrate and two patients with contact hypersensitivity to hydrocortisone-17-butyra...

journal_title：Journal of the American Academy of Dermatology

authors： Lauerma AI,Reitamo S,Maibach HI

更新日期：1991-02-01 00:00:00

abstract：:In a 4-year-old boy with steriod-resistant syndrome and extreme hyperlipidemia, an intense pruritic papular eruption developed on the trunk, buttocks, and extensor surface of the extremities. Findings from a skin biopsy specimen were consistent with an eruptive xanthoma. The patient was treated with gemfibrozil (Lopid...

journal_title：Journal of the American Academy of Dermatology

authors： Teltscher J,Silverman RA,Stork J

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The tumor necrosis factor (TNF) inhibitor etanercept has been demonstrated to be safe and effective for treating chronic plaque psoriasis in 3 clinical trials. OBJECTIVES:To refine efficacy results for etanercept on the basis of a larger population size through the integration of the 3 studies, and to deter...

journal_title：Journal of the American Academy of Dermatology

authors： Gordon K,Korman N,Frankel E,Wang H,Jahreis A,Zitnik R,Chang T

更新日期：2006-03-01 00:00:00

abstract：:A single application (16 to 20 hours) of 1% gamma benzene hexachloride (GBH) lotion, when applied to a total island population of 178 persons in which seventy-four clinically had scabies, resulted in a cure rate of over 98%. Re-examination of the population at 10 and 21 weeks revealed only one remaining individual sti...

journal_title：Journal of the American Academy of Dermatology

authors： Taplin D,Arrue C,Walker JG,Roth WI,Rivera A

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Several clinical studies have focused on the therapeutic effects of interferon gamma (IFN-gamma) in patients with severe atopic dermatitis (AD), although the dosage of recombinant IFN-gamma (rIFN-gamma), therapeutic schedule, and the degree of clinical improvement were different among studies. Although the e...

journal_title：Journal of the American Academy of Dermatology

authors： Jang IG,Yang JK,Lee HJ,Yi JY,Kim HO,Kim CW,Kim TY

更新日期：2000-06-01 00:00:00

abstract：:We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bon...

journal_title：Journal of the American Academy of Dermatology

authors： Welsh O,Sauceda E,Gonzalez J,Ocampo J

更新日期：1987-09-01 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN 1) predisposes affected persons to neoplasms of the parathyroid glands, the endocrine pancreas, the anterior pituitary, and the duodenum. We report the first case of adult-onset multiple angiofibromas of the central face associated with MEN 1. Seven siblings also developed adul...

journal_title：Journal of the American Academy of Dermatology

authors： Hoang-Xuan T,Steger JW

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Patients with onychomycosis may experience physical impairment and psychological and social limitations related to their infection. OBJECTIVE:The object of this study was to compare health-related quality-of-life scores of patients with onychomycosis with those of a control group. METHODS:The interview ins...

journal_title：Journal of the American Academy of Dermatology

authors： Lubeck DP

更新日期：1998-05-01 00:00:00

abstract：:Vohwinkel's syndrome or keratoderma hereditaria mutilans is a diffuse, honeycombed, palmar, and plantar keratosis usually accompanied by pseudoainhum near the distal interphalangeal creases. The mutilating keratoderma associated with sensorineural hearing loss is thought to have an etiologic basis, resting on a mutati...

journal_title：Journal of the American Academy of Dermatology

authors： Solis RR,Diven DG,Trizna Z

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Relatively few persons with obsessive-compulsive disorder (OCD) come to psychiatric clinics for treatment. Our hypothesis was that patients with a form of OCD that involves compulsive hand and body washing might initially seek treatment from a dermatologist. OBJECTIVE:Our purpose was to screen patients atte...

journal_title：Journal of the American Academy of Dermatology

authors： Hatch ML,Paradis C,Friedman S,Popkin M,Shalita AR

更新日期：1992-04-01 00:00:00

abstract：:Melanomas are rare in patients who have albinism, compared with the frequent occurrence of squamous cell carcinomas and basal cell carcinomas. This report describes amelanotic metastatic melanoma in a 58-year-old Japanese man who had tyrosinase-positive oculocutaneous albinism. A prolonged bleeding time, facioscapuloh...

journal_title：Journal of the American Academy of Dermatology

authors： Ihn H,Nakamura K,Abe M,Furue M,Takehara K,Nakagawa H,Ishibashi Y

更新日期：1993-05-01 00:00:00

abstract：:The painful orogenital ulcerations of Behçet's disease are among the major symptoms of patients and are often intractable. We assessed the efficacy of granulocyte and monocyte adsorption apheresis therapy in two patients, a 21-year-old man with orogenital ulcerations and a 50-year-old woman with genital ulceration and...

journal_title：Journal of the American Academy of Dermatology

authors： Kanekura T,Gushi A,Iwata M,Fukumaru S,Sakamoto R,Kawahara K,Maruyama I,Kanzaki T

更新日期：2004-08-01 00:00:00

abstract：UNLABELLED:Skin cancer is the most common cancer in human beings. The increased incidence of skin cancer has brought much attention to the process by which these tumors develop and how they can be prevented. Efforts have been made to educate the public about the importance of protecting skin from excessive ultraviolet ...

journal_title：Journal of the American Academy of Dermatology

authors： Wright TI,Spencer JM,Flowers FP

更新日期：2006-06-01 00:00:00

abstract：:Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...

journal_title：Journal of the American Academy of Dermatology

authors： Prado R,Ellis LZ,Gamble R,Funk T,Arbuckle HA,Bruckner AL

更新日期：2012-12-01 00:00:00

abstract：:Splinter hemorrhages are non-blanchable usually distal reddish-brown linear hemorrhages beneath the nails. Among a variety of etiologic factors reported, trauma is the most common cause. A 26-year-old Hispanic female presented with asymptomatic, extensive fingernail hemorrhages of two months duration. There was no his...

journal_title：Journal of the American Academy of Dermatology

authors： Saladi RN,Persaud AN,Rudikoff D,Cohen SR

更新日期：2004-02-01 00:00:00

abstract：:A patient with a 10-year history of an acquired, scarring bullous eruption localized to the anterior surfaces of the lower extremities is described. Clinical, histologic, and electron microscopic features of an acquired form of epidermolysis bullosa are shown to occur in the absence of immune deposits, a finding not p...

journal_title：Journal of the American Academy of Dermatology

authors： Unis ME,Pfau RG,Patel H,Takahashi Y,Anhalt GJ

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Dermatoscopy is the most commonly used noninvasive tool for the diagnosis of pigmented skin lesions, but few studies have investigated the value of cytology in the identification of those lesions. OBJECTIVE:We compared the accuracy of dermatoscopy with that of the Tzanck smear test in the diagnosis of pigme...

journal_title：Journal of the American Academy of Dermatology

authors： Durdu M,Baba M,Seçkin D

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Melanoma is one of the deadliest forms of skin cancer, having a high metastatic potential and afflicting all age groups. The need for successful preventative measures is particularly urgent as metastatic melanoma is largely incurable. The beneficial role of nutrition and other natural compounds in the preven...

journal_title：Journal of the American Academy of Dermatology

authors： Tong LX,Young LC

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：:The psychosocial impact of infection with human immunodeficiency virus (HIV) can be viewed from three perspectives: (1) the issues focused by acquired immunodeficiency syndrome (AIDS), (2) the persons affected, and (3) the emotions encountered. Among the many issues faced by AIDS patients, their families, and their ca...

journal_title：Journal of the American Academy of Dermatology

authors： Cline DJ

更新日期：1990-06-01 00:00:00

abstract：:Papular mucinosis is a rare, idiopathic cutaneous mucinosis that is typically chronic and progressively severe. We present a case of a 59-year-old woman with a 6-month history of a dramatic papular eruption on her face and neck, with no associated internal organ involvement. A biopsy specimen demonstrated increased de...

journal_title：Journal of the American Academy of Dermatology

authors： Sperber BR,Allee J,James WD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Dermatophytic infections of the fingernail can be effectively treated with oral antifungal agents; however, a long duration of treatment, generally several months, is required for cure. OBJECTIVE:Our purpose was to compare the efficacies of short-duration treatment with terbinafine and griseofulvin in the m...

journal_title：Journal of the American Academy of Dermatology

authors： Haneke E,Tausch I,Bräutigam M,Weidinger G,Welzel D

更新日期：1995-01-01 00:00:00

abstract：:Superantigens (SAgs) are virulent polypeptides that are produced by a variety of infectious organisms. They are capable of causing nonspecific T cell activation by circumventing normal antigen processing in the human host. The genetic makeup of the host plays a role in conferring susceptibility or protection against S...

journal_title：Journal of the American Academy of Dermatology

authors： Macias ES,Pereira FA,Rietkerk W,Safai B

更新日期：2011-03-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00