The risk of rash associated with ipilimumab in patients with cancer: a systematic review of the literature and meta-analysis.

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) is a relatively common tumor with increasing prevalence and substantial morbidity. A variety of treatment modalities are available, though margin-control surgery offers the highest cure rate. We were interested in comparing long-term outcomes of Mohs micrographic surgery (MMS) versus sta...

journal_title：Journal of the American Academy of Dermatology

authors： Walling HW,Scupham RK,Bean AK,Ceilley RI

更新日期：2007-10-01 00:00:00

abstract：:We describe a family with the unusual association of Cowden's disease and Bannayan-Riley-Ruvalcaba syndrome. The father has characteristic mucocutaneous features that are palmoplantar keratoses, multiple facial papules, oral papillomatoses, lipomas, and vitiligo with involvement of the thyroid and digestive tract. The...

journal_title：Journal of the American Academy of Dermatology

authors： Perriard J,Saurat JH,Harms M

更新日期：2000-02-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:It is generally believed that dihydrotestosterone is one of the pivotal mediators of hair loss in androgenetic alopecia (AGA). Finasteride, which blocks the conversion of testosterone to dihydrotestosterone, has now become an integral part of the current treatment approaches for male AGA. Several lines of ev...

journal_title：Journal of the American Academy of Dermatology

authors： Tang L,Bernardo O,Bolduc C,Lui H,Madani S,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious. OBJECTIVE:To evaluate the comparative efficacy and safety of antiscabietic agents. METHODS:A systematic review of randomized controlled trials was conducted. Direct and network meta-analyses were applied to...

journal_title：Journal of the American Academy of Dermatology

authors： Thadanipon K,Anothaisintawee T,Rattanasiri S,Thakkinstian A,Attia J

更新日期：2019-05-01 00:00:00

abstract：:We report the case of an otherwise healthy 37-year-old man who had had bilateral enucleation during early childhood for bilateral retinoblastomas, in addition to two cutaneous melanomas (the first appearing at age 27 years). He also had dysplastic melanocytic nevi and a history of cutaneous melanoma in his mother. Ret...

journal_title：Journal of the American Academy of Dermatology

authors： Albert LS,Sober AJ,Rhodes AR

更新日期：1990-11-01 00:00:00

abstract：:Six men suffering from acute dermatitis had positive patch tests to Larrea (creosote bush). The lesions preferentially involved sun-exposed sites, simulating a photodermatitis, but also were on the legs and scrotum. Our findings were more consistent with contact allergy than with a primary irritant or a phototoxic res...

journal_title：Journal of the American Academy of Dermatology

authors： Leonforte JF

更新日期：1986-02-01 00:00:00

abstract：:Part 3 of this 4-part continuing medical education series reviews several important infectious complications of corticosteroid use, including a focus on pneumocystis pneumonia (PCP) prophylaxis, tuberculosis, viral hepatitis, and other infections, followed by a discussion of vaccination recommendations in immunosuppre...

journal_title：Journal of the American Academy of Dermatology

authors： Caplan A,Fett N,Rosenbach M,Werth VP,Micheletti RG

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Psoriasis and migraine are common conditions with potential overlap of pathophysiological mechanisms. Both these diseases have been associated with increased cardiovascular risk but little is known about their interplay. OBJECTIVE:We sought to investigate the link between psoriasis, and the risk of new-onse...

journal_title：Journal of the American Academy of Dermatology

authors： Egeberg A,Mallbris L,Hilmar Gislason G,Skov L,Riis Hansen P

更新日期：2015-11-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：:Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited available data suggest significant unmet care needs and low rates of palliati...

journal_title：Journal of the American Academy of Dermatology

authors： Thompson LL,Chen ST,Lawton A,Charrow A

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Inherited susceptibility genes have been associated with histopathologic characteristics of tumors. OBJECTIVE:We sought to identify associations between histology of melanomas and CDKN2A genotype. METHODS:This was a case-control study design comparing 28 histopathologic tumor features among individuals wit...

journal_title：Journal of the American Academy of Dermatology

authors： Sargen MR,Kanetsky PA,Newton-Bishop J,Hayward NK,Mann GJ,Gruis NA,Tucker MA,Goldstein AM,Bianchi-Scarra G,Puig S,Elder DE

更新日期：2015-03-01 00:00:00

abstract：:It has been demonstrated recently in mycosis fungoides and lichen planus that T lymphocyte subsets may be identified in cutaneous lymphocytic infiltrates using the immunoperoxidase technic in conjunction with monoclonal antibodies produced by the technic of Kohler and Milstein. This communication describes the applica...

journal_title：Journal of the American Academy of Dermatology

authors： McMillan EM,Wasik R,Everett MA

更新日期：1982-01-01 00:00:00

abstract：:Reflectance confocal microscopy (RCM) is a high-resolution, noninvasive tool that is currently approved by the US Food and Drug Administration for obtaining and interpreting images of the skin and cutaneous neoplasms with the goal of decreasing unnecessary biopsy procedures in patients with benign lesions. The second ...

journal_title：Journal of the American Academy of Dermatology

authors： Shahriari N,Grant-Kels JM,Rabinovitz H,Oliviero M,Scope A

更新日期：2021-01-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：:Tissue resistance to insulin is a major feature underlying the development of acanthosis nigricans in many patients. We report two unusual cases of acanthosis nigricans with contrasting forms of insulin resistance and propose an algorithm for the evaluation of patients with acanthosis nigricans. Further, we present a ...

journal_title：Journal of the American Academy of Dermatology

authors： Rendon MI,Cruz PD Jr,Sontheimer RD,Bergstresser PR

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Biologic agents may predispose patients to skin and soft tissue infections (SSTIs). Guidelines recommend discontinuing the agent pre-operatively; the true risk of infection is unclear. OBJECTIVES:To assess the incidence of SSTIs in patients on biologic agents for all clinical indications. A secondary aim is...

journal_title：Journal of the American Academy of Dermatology

authors： Nguyen ED,Gabel CK,Kroshinsky D

更新日期：2020-05-05 00:00:00

abstract：:Oral retinoids are among the drugs of choice for pustular and erythrodermic psoriasis. In addition, retinoids are effective in combination with other topical and systemic agents for the treatment of plaque-type psoriasis. Acitretin, the active retinoid metabolite, has replaced etretinate in retinoid therapy of psorias...

journal_title：Journal of the American Academy of Dermatology

authors： Katz HI,Waalen J,Leach EE

更新日期：1999-09-01 00:00:00

abstract：:We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully ...

journal_title：Journal of the American Academy of Dermatology

authors： Gardeazábal J,Arregui MA,Gil N,Landa N,Ratón JA,Diáz-Pérez JL

更新日期：1992-11-01 00:00:00

abstract：:Mycophenolate mofetil (MMF) has been widely used as an immunosuppressant in organ transplantation. MMF has recently been added to therapeutic regimens for skin disorders. Expanding the use of MMF in dermatology, we describe additional patients with autoimmune and inflammatory skin diseases, including 4 cases of pemphi...

journal_title：Journal of the American Academy of Dermatology

authors： Nousari HC,Sragovich A,Kimyai-Asadi A,Orlinsky D,Anhalt GJ

更新日期：1999-02-01 00:00:00

abstract：:Kapos's varicelliform eruption usually occurs in persons with active skin disease of various types; however, in atopic dermatitis the condition may occur when the underlying disease is inactive. Two cases of widespread herpes simplex infection associated with Darier's disease are reported. In both cases, infection occ...

journal_title：Journal of the American Academy of Dermatology

authors： Toole JW,Hofstader SL,Ramsay CA

更新日期：1979-10-01 00:00:00

abstract：:A case of porphyria cutanea tarda in a human immunodeficiency virus-infected patient with hemophilia is reported. Onset of skin manifestations of porphyria cutanea tarda coincided with deterioration of immune function. However, acquired immunodeficiency syndrome has not yet developed with a follow-up interval of 39 mo...

journal_title：Journal of the American Academy of Dermatology

authors： Conlan MG,Hoots WK

更新日期：1992-05-01 00:00:00

abstract：:During 1 year of continuous suppressive therapy for frequent recurrent genital herpes, about 44% of patients taking 400 mg acyclovir twice a day had no recurrences and 4% of patients taking placebo had no recurrences (i.e., fewer patients taking acyclovir had recurrences, and when they did there were fewer recurrences...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Desonide, a class 6 nonfluorinated topical corticosteroid, has been available for more than two decades. Hydrocortisone is widely used in the treatment of dermatoses in children. OBJECTIVE:Our purpose was to compare the safety and efficacy of desonide ointment and 1.0% hydrocortisone ointment in children wi...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo J,Levy M,Lucky A,Shavin J,Goldberg G,Dunlap F,Hinds A,Strelka L,Baker M,Tuley M

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Klippel-Trenaunay syndrome (KTS) is a vascular malformation overgrowth syndrome characterized by capillary malformation, venous malformation, and limb overgrowth, with or without lymphatic malformation. Patients are at an increased risk of hemorrhage and venous thromboembolism (VTE). Consequently, women with...

journal_title：Journal of the American Academy of Dermatology

authors： Marvin EK,Schoch JJ,Nguyen H,Anderson KR,Driscoll DJ,Rose CH,Bendel EC,Tollefson MM

更新日期：2019-12-01 00:00:00

abstract：:Multiple cell types and their factors and cytokines are involved in regulating the immune response in inflammatory skin diseases. Stimulatory and inhibitory factors interact to determine whether the immune response is regulated up or down. Normally, stimulatory signals are counteracted by inhibitory signals to prevent...

journal_title：Journal of the American Academy of Dermatology

authors： Baadsgaard O,Fisher GJ,Voorhees JJ,Cooper KD

更新日期：1990-12-01 00:00:00

abstract：:An unusual American epidemic consisting of twenty cases of granuloma inguinale is chronicled. Evidence from this series supports the venereal transmission of the disorder. Trimethoprim/sulfamethoxazole proved to be a safe and effective therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Tschen JA,Ramsdell W,Moore J,Markham B

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:To prevent DNA damage caused by the ultraviolet (UV) radiation of sunlight, sunscreens are commonly used to protect human skin. Current analysis of sunscreens' effectiveness is done through complicated procedures, including human exposure. OBJECTIVE:We sought to design a simple system using thymidine-thymid...

journal_title：Journal of the American Academy of Dermatology

authors： Maw KL,Caton-Williams J,Salon J,Huang Z

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00