Mycophenolate mofetil in autoimmune and inflammatory skin disorders.

abstract：BACKGROUND:Hereditary palmoplantar keratoderma (HPPK), type papulosa, is rare, and epidemiologic data are sporadic and inconsistent. An epidemiologic population study of this disease has not been performed previously. OBJECTIVE:We performed a large population study on prevalence of HPPK, type papulosa, in Croatia. ME...

journal_title：Journal of the American Academy of Dermatology

authors： Stanimirović A,Kansky A,Basta-Juzbasić A,Skerlev M,Beck T

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00

abstract：:The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

journal_title：Journal of the American Academy of Dermatology

authors： Brady SP

更新日期：2004-01-01 00:00:00

abstract：:Dermatologists frequently are consulted by a pregnant patient or a woman of childbearing age who desires acne therapy. Because there are no published studies in which women took acne medications throughout pregnancy, information about safety must be obtained indirectly from studies in which the agents were taken for a...

journal_title：Journal of the American Academy of Dermatology

authors： Rothman KF,Pochi PE

更新日期：1988-09-01 00:00:00

abstract：:Desmoplastic malignant melanoma is a rare neoplasm consisting primarily of spindle-shaped melanoma cells embedded in a fibrous stroma, with approximately 6% of cases occurring in the lip. A literature search revealed that most reported cases occur in sun-exposed areas in older men. Few cases of desmoplastic malignant ...

journal_title：Journal of the American Academy of Dermatology

authors： Hui JI,Linden KG,Barr RJ

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Epidermal spongiosis with exocytosis of eosinophils (ES) has been reported in biopsy specimens from patients with various dermatoses. Its diagnostic value and the patient's outcome remain poorly understood in those cases in which ES is not associated directly with diagnostic features of a bullous dermatosis....

journal_title：Journal of the American Academy of Dermatology

authors： Ruiz E,Deng JS,Abell EA

更新日期：1994-06-01 00:00:00

abstract：:A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

journal_title：Journal of the American Academy of Dermatology

authors： De Villez RL

更新日期：1987-03-01 00:00:00

abstract：INTRODUCTION:Intravenous immunoglobulin (IVIG) is used to treat many inflammatory and autoimmune disorders and although generally well tolerated, cutaneous side effects occur. OBJECTIVE:We reviewed reports of pompholyx and eczematous reactions associated with IVIG. METHODS:A literature search was performed using the ...

journal_title：Journal of the American Academy of Dermatology

authors： Gerstenblith MR,Antony AK,Junkins-Hopkins JM,Abuav R

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Several changing clinical and histopathologic melanoma trends occurred from the 1950s to the 1980s. OBJECTIVE:The purpose of this study was to evaluate melanoma trends during the past decade and to compare present trends to those documented during the past four decades. METHODS:Sex, age at diagnosis, locat...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson TM,Dolan OM,Hamilton TA,Lu MC,Swanson NA,Lowe L

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Cutaneous polyarteritis nodosa (cPAN) is a skin medium vessel neutrophilic arteritis with livedo, nodules, and ulcerations. Macular lymphocytic arteritis (MLA) is a small arteritis with erythematous or pigmented macules and typical histologic features (a lymphocytic infiltrate, concentric fibrin ring, no dis...

journal_title：Journal of the American Academy of Dermatology

authors： Buffiere-Morgado A,Battistella M,Vignon-Pennamen MD,de Masson A,Rybojad M,Petit A,Cordoliani F,Begon E,Flageul B,Mahr A,Bagot M,Bouaziz JD

更新日期：2015-12-01 00:00:00

abstract：:With the growth of dermatologic surgery the appropriate use of local anesthesia is becoming an important issue. Thoughtful use of local anesthesia can improve the patient's experience and facilitate the surgical procedure. In this review we discuss historical and pharmacologic aspects of local anesthetic agents. Empha...

journal_title：Journal of the American Academy of Dermatology

authors： Grekin RC,Auletta MJ

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae infection is associated with extrapulmonary complications, including mucocutaneous eruptions. These eruptions, which have been termed either "Stevens-Johnson syndrome" or "erythema multiforme" in the literature, may differ from drug-induced Stevens-Johnson syndrome or viral-associated e...

journal_title：Journal of the American Academy of Dermatology

authors： Canavan TN,Mathes EF,Frieden I,Shinkai K

更新日期：2015-02-01 00:00:00

abstract：:Tzaraat refers to a group of skin diseases that, according to the Old Testament, renders one ritually unclean. Analysis of the text reveals that there are four categories of lesions discussed. Each category has a primary lesion as well as specific secondary changes. The primary lesions include depigmented lesions on p...

journal_title：Journal of the American Academy of Dermatology

authors： Freilich AR

更新日期：1982-01-01 00:00:00

abstract：:The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bernal JE,Duran de Rueda MM,Ordonez CP,Duran C,de Brigard D

更新日期：1990-06-01 00:00:00

abstract：:We describe a female patient with an acute purpuric and bullous eruption mainly affecting the lower aspect of the legs. Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation. Intermediate hyperhomocysteinemia and transient antiphospholipid antibodies were evidenced ...

journal_title：Journal of the American Academy of Dermatology

authors： Martin L,Armingaud P,Georgescu V,Matre F,Legac E,Estève E

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Retrospective data have suggested the effectiveness of intravenous immunoglobulins (IVIG) for solar urticaria (SU). OBJECTIVE:We sought to prospectively assess the efficacy of IVIG for SU. METHODS:We conducted a multicentric phase II study to test the efficacy of a single course of IVIG (2 g/kg) in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Aubin F,Porcher R,Jeanmougin M,Léonard F,Bedane C,Moreau A,Schmutz JL,Marguery MC,Adamski H,Viguier M,Société Française de Photodermatologie.

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Non-melanoma skin cancers (NMSCs) are increased in organ transplant recipients, but transplant and immunocompetent squamous and basal cell carcinomas (SCCs, BCCs) have not been compared previously in a single-center study. OBJECTIVE:To compare clinicopathologic features of transplant and immunocompetent NMS...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood CA,Proby CM,McGregor JM,Sheaff MT,Leigh IM,Cerio R

更新日期：2006-02-01 00:00:00

abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG 3rd,Giblin WL,James WD

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Isotretinoin is a very effective drug for treating severe recalcitrant nodular acne. A new micronized formulation of isotretinoin has been shown to be clinically equivalent to standard isotretinoin with improved bioavailability and minimal food effect. The safety profile of the micronized formulation has not...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Leyden JJ,Lucky AW,Lookingbill DP,Drake LA,Hanifin JM,Lowe NJ,Jones TM,Stewart DM,Jarratt MT,Katz I,Pariser DM,Pariser RJ,Tschen E,Chalker DK,Rafal ES,Savin RP,Roth HL,Chang LK,Baginski DJ,Kempers S,M

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

journal_title：Journal of the American Academy of Dermatology

authors： Reinhold U,Seiter S,Ugurel S,Tilgen W

更新日期：1999-08-01 00:00:00

abstract：:There has been a resurgence of syphilis in the past decade. Uncommonly, diffuse hair loss, termed essential alopecia, is the only sign of syphilitic infection. We describe two patients with syphilis in whom the first sign of disease was alopecia and discuss the clinical and histopathologic findings of essential syphil...

journal_title：Journal of the American Academy of Dermatology

authors： Cuozzo DW,Benson PM,Sperling LC,Skelton HG 3rd

更新日期：1995-05-01 00:00:00

abstract：:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unknown origin that is characterized clinically by annular patches with erythematous borders and hypopigmented centers and histologically by loss of elastic fibers and elastophagocytosis. We report a case of AEGCG in an 8-month-ol...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HW,Lee MW,Choi JH,Moon KC,Koh JK

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:No large studies have defined the best treatment of actinic cheilitis. METHODS:We conducted a systematic review to define the best therapies for actinic cheilitis in clinical response and recurrences. RESULTS:We first identified 444 papers, and 49 were finally considered, including 789 patients and 843 tre...

journal_title：Journal of the American Academy of Dermatology

authors： Lai M,Pampena R,Cornacchia L,Pellacani G,Peris K,Longo C

更新日期：2020-09-01 00:00:00

abstract：:An article titled "Current issues in dermatologic office-based surgery" was published in the JAAD in October 1999 (volume 41, issue 4, pp. 624-634). The article was developed by the Joint American Academy of Dermatology/American Society for Dermatologic Surgery Liaison Committee. A number of subjects were addressed in...

journal_title：Journal of the American Academy of Dermatology

authors： Hanke CW,Moy RL,Roenigk RK,Roenigk HH Jr,Spencer JM,Tierney EP,Bartus CL,Bernstein RM,Brown MD,Busso M,Carruthers A,Carruthers J,Ibrahimi OA,Kauvar AN,Kent KM,Krueger N,Landau M,Leonard AL,Mandy SH,Rohrer TE,Sadic

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no a...

journal_title：Journal of the American Academy of Dermatology

authors： Segura S,Pujol RM,Trindade F,Requena L

更新日期：2008-11-01 00:00:00

abstract：:The number of cases of mycotic infections are increasing, presenting physicians today with an unprecedented challenge in handling the treatment and prophylactic control of these disorders. The increase in mycotic disorders is due to many factors, such as longer life span, organ transplantation, and the acquired immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Jacobs PH

更新日期：1990-09-01 00:00:00

abstract：:The role of estrogens in the development of skin cancer is controversial. Sex steroids have a profound effect on the epidermis and epidermal appendages. Estradiol in pharmacologic doses has been reported to stimulate basal cell carcinoma in an animal model. Sex hormones act by means of a specific protein receptor. In ...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers GS,Flowers JL,Pollack SV,McCarty KS Jr

更新日期：1988-05-01 00:00:00

abstract：:We describe four patients who developed basal cell carcinoma (BCC) among multiple facial trichoepitheliomas. The only clinical feature that distinguished the carcinomas from the trichoepitheliomas was their larger size in three of the four patients. None of the lesions ulcerated. Whether the BCCs developed independent...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson SC,Bennett RG

更新日期：1993-02-01 00:00:00

abstract：:The Cosmetic Ingredient Review (CIR) program was established in 1976 by the Cosmetics, Toiletry, and Fragrance Association, with the support of the Food and Drug Administration (FDA) and the Consumer Federation of America (CFA). CIR performs independent, expert reviews to determine if ingredients used in cosmetics are...

journal_title：Journal of the American Academy of Dermatology

authors： Bergfeld WF,Belsito DV,Marks JG Jr,Andersen FA

更新日期：2005-01-01 00:00:00