Actinic prurigo among the Chimila Indians in Colombia: HLA studies.

abstract：:The primary serum proteinase inhibitor is alpha 1-antitrypsin, and deficiency of this enzyme has been associated with a variety of systemic and cutaneous disorders. We report cutaneous vasculitis in a 49-year-old man with alpha 1-antitrypsin deficiency. His condition persisted despite treatment with colchicine, predni...

journal_title：Journal of the American Academy of Dermatology

authors： Dowd SK,Rodgers GC,Callen JP

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Severe atopic dermatitis (AD) is increasingly treated with systemic immuno-modulatory drugs yet their safety is unclear. OBJECTIVE:We evaluated the comparative risk of serious bacterial and opportunistic infections among users of systemic immuno-modulatory medications in patients with severe AD in routine c...

journal_title：Journal of the American Academy of Dermatology

authors： Schneeweiss MC,Perez-Chada L,Merola JF

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Degos disease or malignant atrophic papulosis is a rare occlusive vasculopathic disease characterized by pathognomonic cutaneous lesions and frequently fatal systemic involvement. The etiology of malignant atrophic papulosis remains unclear, and there is currently no effective treatment for malignant atrophi...

journal_title：Journal of the American Academy of Dermatology

authors： Meephansan J,Komine M,Hosoda S,Tsuda H,Karakawa M,Murata S,Demitsu T,Ohtsuki M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Safety profiles of systemic biologic agents for the treatment of psoriasis and psoriatic arthritis (PsA) encompass a wide spectrum of adverse events. To date, no uniform evidence-based guidelines exist regarding screening and monitoring patients who are undergoing biologic therapy. OBJECTIVE:We sought to id...

journal_title：Journal of the American Academy of Dermatology

authors： Ahn CS,Dothard EH,Garner ML,Feldman SR,Huang WW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Multiple myeloma (MM) is a plasma cell dyscrasia characterized by a clonal proliferation of plasma cells that produces a monoclonal protein. There are dermatologic disorders that have been associated with MM, such as amyloidosis, cryoglobulinemia, POEMS syndrome, normolipemic plane xanthoma, and plasmacytoma...

journal_title：Journal of the American Academy of Dermatology

authors： Bayer-Garner IB,Smoller BR

更新日期：2003-04-01 00:00:00

abstract：:Isotretinoin is used to treat severe and recalcitrant acne. Possible side effects include depression, suicide, and suicidal ideation; however, other studies suggest isotretinoin may improve mood and quality of life. Although iPLEDGE consenting warns about the risk of depression and suicidal ideation, there is no recom...

journal_title：Journal of the American Academy of Dermatology

authors： Schrom K,Nagy T,Mostow E

更新日期：2016-07-01 00:00:00

abstract：:The fixed cutaneous type of sporotrichosis is difficult to diagnose because clinical lesions are variable in appearance and the cells of Sporothrix schenckii are usually scarce in skin biopsy specimens. We have described two patients with lesions of fixed cutaneous sporotrichosis that resembled other inflammatory skin...

journal_title：Journal of the American Academy of Dermatology

authors： Bickley LK,Berman IJ,Hood AF

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:Although etanercept is used as a continuous therapy for moderate to severe plaque psoriasis, intermittent use may be necessary in some instances. OBJECTIVE:In this randomized, open-label study, we evaluated the effectiveness and safety of continuous versus interrupted etanercept therapy. METHODS:All patien...

journal_title：Journal of the American Academy of Dermatology

authors： Moore A,Gordon KB,Kang S,Gottlieb A,Freundlich B,Xia HA,Stevens SR

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Small open studies of patients at high risk for squamous cell carcinoma (SCC) of the skin suggest that oral retinoid use reduces the risk of these tumors. Among patients at lower risk, randomized trials of low doses of retinoids did not demonstrate significant chemopreventive effects. Patients with psoriasis...

journal_title：Journal of the American Academy of Dermatology

authors： Nijsten TE,Stern RS

更新日期：2003-10-01 00:00:00

abstract：:Given the increasing incidence and prevalence of skin cancer, dermatologists are more frequently recommending sunscreens to their patients. However, the safety of titanium dioxide and zinc oxide nanosized particles in the majority of sunscreens has come under scrutiny from governments and the general public. We sought...

journal_title：Journal of the American Academy of Dermatology

authors： Newman MD,Stotland M,Ellis JI

更新日期：2009-10-01 00:00:00

abstract：:Infantile perineal protrusion, a relatively newly recognized condition, is underreported in both the dermatologic and pediatric literature. The name "infantile perineal protrusion" has evolved based on the typical anatomic location, morphologic features, and prevalence in prepubertal children. It occurs in 3 settings:...

journal_title：Journal of the American Academy of Dermatology

authors： Khachemoune A,Guldbakke KK,Ehrsam E

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Pemphigus vulgaris (PV) shows autoimmune reaction against desmoglein 3 (Dsg3), whereas paraneoplastic pemphigus (PNP) shows autoimmune reaction against Dsg3 as well as numerous members of the plakin family. It has been demonstrated that in PV, dominant epitopes reside in N-terminal adhesive regions of Dsg3 a...

journal_title：Journal of the American Academy of Dermatology

authors： Futei Y,Amagai M,Hashimoto T,Nishikawa T

更新日期：2003-12-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Rosacea is a common problem that is underdiagnosed; if left untreated can result in physical disfigurement and emotional distress. OBJECTIVE:We reviewed the current literature to determine the degree of psychosocial impact of rosacea and the importance of treatment. We also reviewed the current treatment op...

journal_title：Journal of the American Academy of Dermatology

authors： Moustafa F,Lewallen RS,Feldman SR

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The epidemiology of pediatric melanoma is distinct from that seen in adults. This is more distinguishable when pediatric patients are separated into prepubertal and adolescent groups. OBJECTIVE:In this study, we compared epidemiologic, clinical, histologic, and molecular characteristics of pediatric superfi...

journal_title：Journal of the American Academy of Dermatology

authors： Verzì AE,Bubley JA,Haugh AM,Zhang B,Wagner A,Kruse L,West DP,Wayne J,Guitart J,Gerami P

更新日期：2017-11-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is an endogenous reactive oxygen species that contributes to oxidative stress directly as a molecular oxidant and indirectly through free radical generation. Topically applied 1% to 45% H2O2 can be used for a range of clinical purposes, which will be reviewed here in addition to its safety. In...

journal_title：Journal of the American Academy of Dermatology

authors： Murphy EC,Friedman AJ

更新日期：2019-12-01 00:00:00

abstract：:More than 1100 patients were tested with methylchloroisothiazolinone-methylisothiazolinone, 100 ppm, in aqueous and petrolatum-based patch test materials from 1985 to 1987 by members of the North American Contact Dermatitis Group. Thirteen reactions to the aqueous materials and 10 to the petrolatum-based materials wer...

journal_title：Journal of the American Academy of Dermatology

authors： Rietschel RL,Nethercott JR,Emmett EA,Maibach HI,Storrs FJ,Larsen WG,Adams RM,Taylor JS,Marks JG Jr,Mitchell JC

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:There are limited data on the effectiveness of skin cancer prevention education and early detection programs at beaches. OBJECTIVES:We evaluate 4 strategies for addressing skin cancer prevention in beach settings. METHODS:This prospective study at 4 beaches included 4 intervention conditions: (1) education...

journal_title：Journal of the American Academy of Dermatology

authors： Emmons KM,Geller AC,Puleo E,Savadatti SS,Hu SW,Gorham S,Werchniak AE,Dana-Farber Skin Cancer Screening Group.

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:The association of human herpesvirus 6 (HHV-6) and HHV-7 with pityriasis rosea suggests that systemic drugs directed against HHV may hasten recovery of patients with pityriasis rosea. OBJECTIVE:The purpose of this study was to verify the efficacy of oral acyclovir in the treatment of pityriasis rosea. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Drago F,Vecchio F,Rebora A

更新日期：2006-01-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Seborrheic dermatitis is commonly treated with anti-inflammatory products, including topical corticosteroids. Pimecrolimus cream 1% also exerts anti-inflammatory activity by inhibiting T-cell cytokine production. OBJECTIVE:We sought to compare the efficacy and safety of twice-daily pimecrolimus for treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Wohlhuter RJ,Liu A,Zeller SA,Wenner RA,Bowers S,Schultz JC,Katz HI,McCormick CL,Parneix-Spake A

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Increases in the incidence of malignant melanoma have been among the largest of all cancers in the United States. OBJECTIVE:We report updated trends in melanoma rates among the US white population. METHODS:Incidence and mortality rates were calculated for 1973 to 1994. Trends were examined with stratificat...

journal_title：Journal of the American Academy of Dermatology

authors： Hall HI,Miller DR,Rogers JD,Bewerse B

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies. OBJECTIVE:We sought to investigate the effects of alcohol and smoking on incident psoriasis. METHODS:Alcohol consumption, ...

journal_title：Journal of the American Academy of Dermatology

authors： Dai YX,Wang SC,Chou YJ,Chang YT,Chen TJ,Li CP,Wu CY

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. OBJECTIVE:We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discont...

journal_title：Journal of the American Academy of Dermatology

authors： Piaserico S,Cazzaniga S,Chimenti S,Giannetti A,Maccarone M,Picardo M,Peserico A,Naldi L,Psocare Study Group.

更新日期：2014-02-01 00:00:00

abstract：:Xeroderma pigmentosum is associated with severe actinic degeneration of the skin. Our patient with xeroderma pigmentosum showed increasing actinic damage in some areas covered by clothes. We therefore performed a complete evaluation of the patient's exposure to ultraviolet radiation. This included transmission measure...

journal_title：Journal of the American Academy of Dermatology

authors： Bech-Thomsen N,Wulf HC,Ullman S

更新日期：1991-02-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：DISCLAIMER:Adherence to these guidelines will not ensure successful treatment in every situation. Furthermore, these guidelines should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propri...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Krowchuk DP,Leyden JJ,Lucky AW,Shalita AR,Siegfried EC,Thiboutot DM,Van Voorhees AS,Beutner KA,Sieck CK,Bhushan R,American Academy of Dermatology\/American Academy of Dermatology Association.

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Acne is a multifactorial disease in which androgens appear to play an important role. A low-dose oral contraceptive containing 20 microg of ethinyl estradiol and 100 microg of levonorgestrel (EE/LNG) has been shown to improve biochemical markers of androgenicity. Lowering bioavailable androgens may improve a...

journal_title：Journal of the American Academy of Dermatology

authors： Leyden J,Shalita A,Hordinsky M,Swinyer L,Stanczyk FZ,Weber ME

更新日期：2002-09-01 00:00:00

abstract：:A single application (16 to 20 hours) of 1% gamma benzene hexachloride (GBH) lotion, when applied to a total island population of 178 persons in which seventy-four clinically had scabies, resulted in a cure rate of over 98%. Re-examination of the population at 10 and 21 weeks revealed only one remaining individual sti...

journal_title：Journal of the American Academy of Dermatology

authors： Taplin D,Arrue C,Walker JG,Roth WI,Rivera A

更新日期：1983-10-01 00:00:00

abstract：:Chronic skin ulcers, which are frequently located on the lower legs, are a common cause of patient morbidity and incur significant direct and indirect costs in their treatment. The most important process for their development is probably impairment of blood flow to the capillaries and small vessels. Examples of such u...

journal_title：Journal of the American Academy of Dermatology

authors： Krull EA

更新日期：1985-02-01 00:00:00