Vulvar melanosis.

Abstract:

:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment.

journal_name

J Am Acad Dermatol

authors

Rudolph RI

doi

10.1016/0190-9622(90)70319-d

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

982-4

issue

5 Pt 2

eissn

0190-9622

issn

1097-6787

pii

0190-9622(90)70319-D

journal_volume

23

pub_type

杂志文章
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    abstract:BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Jewell ML,McCauliffe DP

    更新日期:2000-06-01 00:00:00

  • Treatment of recalcitrant bullous pemphigoid (BP) with a novel protocol: A retrospective study with a 6-year follow-up.

    abstract:BACKGROUND:Bullous pemphigoid is an autoimmune blistering skin disease that predominantly affects the elderly. Conventional therapy using high-dose systemic corticosteroids and immunosuppressive agents can be ineffective in some patients and produce adverse events and relapses. Hence, alternate therapies are required. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2015.11.030

    authors: Ahmed AR,Shetty S,Kaveri S,Spigelman ZS

    更新日期:2016-04-01 00:00:00

  • Livedo reticularis due to multiple cholesterol emboli.

    abstract::Three patients with advanced atherosclerotic vascular disease developed multiple cholesterol emboli. The clinical presentation typically includes livedo reticularis of the lower part of the body and purple toes. Small areas of necrosis and ulceration may be present distally, despite palpable pulses. Muscular and abdom...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70165-x

    authors: Kalter DC,Rudolph A,McGavran M

    更新日期:1985-08-01 00:00:00

  • What have we learned in dermatology from the biologic therapies?

    abstract::Recent advances in our basic understanding of immunology, specifically the roles of various cell types involved in immune response and the action of cytokines they produce, has radically changed our understanding of the origin of inflammatory dermatoses, and other autoimmune diseases. Broadened comprehension of the im...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 信件,评审

    doi:10.1016/j.jaad.2005.10.059

    authors: Nickoloff BJ,Stevens SR

    更新日期:2006-03-01 00:00:00

  • Essential progressive telangiectasia in an autoimmune setting: successful treatment with acyclovir.

    abstract::A unique, progressive syndrome of muscle weakness, ascending telangiectasia, and venous ectasia of the legs developed in a 55-year-old woman with autoimmune thyroiditis. Myopathy was documented by electromyography and electron microscopy. Her constellation of findings is considered to be of autoimmune origin. Treatmen...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)70303-0

    authors: Shelley WB,Shelley ED

    更新日期:1989-11-01 00:00:00

  • A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis siné myositis): a missing link within the spectrum of the idiopathic inflammatory myopathies.

    abstract:OBJECTIVE:Classical dermatomyositis (CDM) patients display the hallmark cutaneous manifestations of dermatomyositis (DM), proximal muscle weakness, and laboratory evidence of myositis. The epidemiology and management of both adult-onset and juvenile-onset CDM has been well characterized. However, the clinical significa...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.10.041

    authors: Gerami P,Schope JM,McDonald L,Walling HW,Sontheimer RD

    更新日期:2006-04-01 00:00:00

  • Efficacy of etanercept in an integrated multistudy database of patients with psoriasis.

    abstract:BACKGROUND:The tumor necrosis factor (TNF) inhibitor etanercept has been demonstrated to be safe and effective for treating chronic plaque psoriasis in 3 clinical trials. OBJECTIVES:To refine efficacy results for etanercept on the basis of a larger population size through the integration of the 3 studies, and to deter...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jaad.2005.11.1088

    authors: Gordon K,Korman N,Frankel E,Wang H,Jahreis A,Zitnik R,Chang T

    更新日期:2006-03-01 00:00:00

  • Gadolinium deposition in nephrogenic systemic fibrosis: an examination of tissue using synchrotron x-ray fluorescence spectroscopy.

    abstract:BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2009.07.018

    authors: High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

    更新日期:2010-01-01 00:00:00

  • Cultivation of Borrelia burgdorferi from human tick bite sites: a guide to the risk of infection.

    abstract:BACKGROUND:The risk of acquiring Lyme disease has been evaluated by xenodiagnostic procedures with laboratory strains of Borrelia burgdorferi and laboratory-reared Ixodes ticks, or by clinical trials in which diagnosis was based on clinical findings, culture, or serologic tests. OBJECTIVE:Our purpose was to determine ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(95)90123-x

    authors: Berger BW,Johnson RC,Kodner C,Coleman L

    更新日期:1995-02-01 00:00:00

  • Topical photodynamic therapy for primary cutaneous B-cell lymphoma: a pilot study.

    abstract::Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2005.10.016

    authors: Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

    更新日期:2006-03-01 00:00:00

  • The proteomic skin profile of moderate-to-severe atopic dermatitis patients shows an inflammatory signature.

    abstract:BACKGROUND:Moderate-to-severe atopic dermatitis (AD) is increasingly recognized as a systemic disease, largely due to proteomic blood studies. There are growing efforts to develop AD biomarkers using minimal tissues. OBJECTIVE:To characterize the AD skin proteomic signature and its relationship with the blood proteome...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2019.10.039

    authors: Pavel AB,Zhou L,Diaz A,Ungar B,Dan J,He H,Estrada YD,Xu H,Fernandes M,Renert-Yuval Y,Krueger JG,Guttman-Yassky E

    更新日期:2020-03-01 00:00:00

  • Expression patterns of the glial cell line-derived neurotrophic factor, neurturin, their cognate receptors GFRalpha-1, GFRalpha-2, and a common signal transduction element c-Ret in the human skin hair follicles.

    abstract:BACKGROUND:Glial cell line-derived neurotrophic factor (GDNF) and a related family member, neurturin (NTN), and their cognate receptors (GFRalpha-1 and GFRalpha-2, for GDNF and NTN, respectively) are distal members of the transforming growth factor-beta superfamily. They are involved in the control of murine hair folli...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2007.10.014

    authors: Adly MA,Assaf HA,Pertile P,Hussein MR,Paus R

    更新日期:2008-02-01 00:00:00

  • Specific skin infiltration as first sign of chronic myelomonocytic leukemia with an unusual phenotype.

    abstract::A patient who had a plaque on his forehead as the first sign of chronic myelomonocytic leukemia (CMML) is described. Histologic studies, which formerly led to the misdiagnosis of non-Hodgkin's lymphoma, revealed CMML with an unusual phenotype. This represents a rare type of CMML for the following reasons: (1) specific...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(96)90088-2

    authors: Braga D,Manganoni AM,Boccaletti V,Pancera C,Marocolo D,Facchetti F,De Panfilis G

    更新日期:1996-11-01 00:00:00

  • Fatal septicemia and bullae caused by non-01 Vibrio cholerae.

    abstract::Bullous lesions associated with non-01 Vibrio cholerae developed in a patient with hepatic cirrhosis who had recently ingested raw oysters. He died of overwhelming sepsis despite 5 days of aggressive antibiotic therapy. Non-01 V. cholerae was isolated from blood, peritoneal fluid, and bullae. The organism produced a c...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(93)70269-y

    authors: Newman C,Shepherd M,Woodard MD,Chopra AK,Tyring SK

    更新日期:1993-11-01 00:00:00

  • Hereditary epidermolytic palmoplantar keratoderma (Vörner type). Report of a familial case and review of the literature.

    abstract::A recent familial case of hereditary epidermolytic palmoplantar keratoderma (Vörner type) that was treated with orally administered etretinate is reported herein. A review of the literature with regard to the clinical, genetic, and laboratory features of this rare genodermatosis is also presented. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(87)70222-9

    authors: Kanitakis J,Tsoitis G,Kanitakis C

    更新日期:1987-09-01 00:00:00

  • Melanotic macule of nail unit and its clinicopathologic spectrum.

    abstract::The clinical and histologic spectrum of melanotic macule of the nail unit is examined and the differences in the clinical appearance of longitudinal melanochychia caused by melanotic macule and by other kinds of proliferations of melanocytes are assessed. We observed that the clinical appearance of the pigmented band ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2005.11.1098

    authors: Husain S,Scher RK,Silvers DN,Ackerman AB

    更新日期:2006-04-01 00:00:00

  • Low-dose UVA phototherapy for treatment of localized scleroderma.

    abstract:BACKGROUND:For treatment of localized scleroderma numerous treatments, including ones with potentially hazardous side effects, are currently used with only limited success. OBJECTIVE:We attempted to determine the efficacy of low-dose UVA1 irradiation in patients with severe localized scleroderma. METHODS:Patients wer...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(98)70533-x

    authors: Kerscher M,Volkenandt M,Gruss C,Reuther T,von Kobyletzki G,Freitag M,Dirschka T,Altmeyer P

    更新日期:1998-01-01 00:00:00

  • Chromoblastomycosis: a review of 100 cases in the state of Rio Grande do Sul, Brazil.

    abstract:BACKGROUND:If not diagnosed earlier, chromoblastomycosis has a chronic evolutional course that may cause several problems, such as difficulty in managing therapy because of the recrudescent character of the disease, potential association with the growth of epidermoid carcinoma in affected regions, and poor quality of l...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2001.112220

    authors: Minotto R,Bernardi CD,Mallmann LF,Edelweiss MI,Scroferneker ML

    更新日期:2001-04-01 00:00:00

  • Pityriasis rubra pilaris and HIV infection.

    abstract::Many cutaneous diseases have been reported in patients with human immunodeficiency virus infection. We report two patients with pityriasis rubra pilaris and human immunodeficiency virus infection. In one patient, the onset of pityriasis rubra pilaris preceded the discovery of human immunodeficiency virus infection. In...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(91)70106-c

    authors: Blauvelt A,Nahass GT,Pardo RJ,Kerdel FA

    更新日期:1991-05-01 00:00:00

  • Hypertrophy in port-wine stains: prevalence and patient characteristics in a large patient cohort.

    abstract:BACKGROUND:Port-wine stains (PWS) may thicken and darken with age. Little is known about the pathogenesis and epidemiology of PWS hypertrophy because of the lack of large studies. OBJECTIVE:We sought to assess the prevalence and characteristics of patients with hypertrophic PWS. METHODS:Medical records and clinical p...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2012.05.027

    authors: van Drooge AM,Beek JF,van der Veen JP,van der Horst CM,Wolkerstorfer A

    更新日期:2012-12-01 00:00:00

  • Treatment of progressive pigmented purpura with oral bioflavonoids and ascorbic acid: an open pilot study in 3 patients.

    abstract:BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(99)70050-2

    authors: Reinhold U,Seiter S,Ugurel S,Tilgen W

    更新日期:1999-08-01 00:00:00

  • Improved clinical outcome and biomarkers in adults with papulopustular rosacea treated with doxycycline modified-release capsules in a randomized trial.

    abstract:BACKGROUND:Patients with rosacea have increased amounts of cathelicidin and protease activity but their usefulness as disease biomarkers is unclear. OBJECTIVE:We sought to evaluate the effect of doxycycline treatment on cathelicidin expression, protease activity, and clinical response in rosacea. METHODS:In all, 170 ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jaad.2016.01.023

    authors: Di Nardo A,Holmes AD,Muto Y,Huang EY,Preston N,Winkelman WJ,Gallo RL

    更新日期:2016-06-01 00:00:00

  • Cost of atopic dermatitis and eczema in the United States.

    abstract:BACKGROUND:Atopic dermatitis/eczema (AD/E) is a common disease. Few studies have attempted to quantify the cost to third-party payers. OBJECTIVE:Our purpose was to identify the annual cost of medical services and prescription drugs for the treatment of AD/E to private insurance and Medicaid payers in the United States...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2002.120528

    authors: Ellis CN,Drake LA,Prendergast MM,Abramovits W,Boguniewicz M,Daniel CR,Lebwohl M,Stevens SR,Whitaker-Worth DL,Cheng JW,Tong KB

    更新日期:2002-03-01 00:00:00

  • Association between atopic dermatitis and contact sensitization: A systematic review and meta-analysis.

    abstract:BACKGROUND:It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower risk. OBJECTIVE:To perf...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jaad.2017.02.001

    authors: Hamann CR,Hamann D,Egeberg A,Johansen JD,Silverberg J,Thyssen JP

    更新日期:2017-07-01 00:00:00

  • Extracutaneous manifestations and complications of inherited epidermolysis bullosa: part I. Epithelial associated tissues.

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    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2009.03.052

    authors: Fine JD,Mellerio JE

    更新日期:2009-09-01 00:00:00

  • Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management.

    abstract::The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in anticancer therapy has been motivated by their specificity for EGFR, which improves their ability to target cancer cells and enhances their safety profile compared with many other conventional chemotherapeutic agents. However, t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2006.09.005

    authors: Hu JC,Sadeghi P,Pinter-Brown LC,Yashar S,Chiu MW

    更新日期:2007-02-01 00:00:00

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    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(93)70155-m

    authors: Resnik KS,Vonderheid EC

    更新日期:1993-07-01 00:00:00

  • Sebaceous carcinoma of the eyelid.

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    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(80)80185-x

    authors: Dixon RS,Mikhail GR,Slater HC

    更新日期:1980-09-01 00:00:00

  • Human papillomavirus-related genital disease in the immunocompromised host: Part I.

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    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2010.12.050

    authors: Gormley RH,Kovarik CL

    更新日期:2012-06-01 00:00:00

  • Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma.

    abstract:BACKGROUND:Several clinical studies have focused on the therapeutic effects of interferon gamma (IFN-gamma) in patients with severe atopic dermatitis (AD), although the dosage of recombinant IFN-gamma (rIFN-gamma), therapeutic schedule, and the degree of clinical improvement were different among studies. Although the e...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Jang IG,Yang JK,Lee HJ,Yi JY,Kim HO,Kim CW,Kim TY

    更新日期:2000-06-01 00:00:00