Specific skin infiltration as first sign of chronic myelomonocytic leukemia with an unusual phenotype.

Abstract:

:A patient who had a plaque on his forehead as the first sign of chronic myelomonocytic leukemia (CMML) is described. Histologic studies, which formerly led to the misdiagnosis of non-Hodgkin's lymphoma, revealed CMML with an unusual phenotype. This represents a rare type of CMML for the following reasons: (1) specific cutaneous involvement is rarely the first sign of CMML; (2) the unique phenotype was detected by immunohistology on lesional skin, specifically, the leukemic infiltrate was CD4-positive and notably negative for CD15, the pan myeloid/monocytic marker.

journal_name

J Am Acad Dermatol

authors

Braga D,Manganoni AM,Boccaletti V,Pancera C,Marocolo D,Facchetti F,De Panfilis G

doi

10.1016/s0190-9622(96)90088-2

subject

Has Abstract

pub_date

1996-11-01 00:00:00

pages

804-7

issue

5 Pt 2

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(96)90088-2

journal_volume

35

pub_type

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