Abstract：
:Treatment of cicatricial pemphigoid is a problem because patients afflicted are elderly, the disease is chronic, systemic agents required for control are potentially toxic (particularly to older patients), and the disease is often in an advanced stage when the diagnosis is established and requires aggressive therapy for control. We selected dapsone as an alternative anti-inflammatory agent because it has provided control in a subset of patients with bullous pemphigoid, five of six who had oral lesions. Twenty-four patients with cicatricial pemphigoid were treated with dapsone. Twenty (83.3%) had partial or complete control with mild to no inflammatory activity. Control was obtained within 4 weeks in eleven of the twenty patients. The use of dapsone was discontinued in two patients because it failed to control their disease and in four patients (two with control) because of drug-related side effects. Cicatricial pemphigoid may be added to the list of dapsone-responsive dermatoses.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Rogers RS 3rd,Seehafer JR,Perry HOdoi
10.1016/s0190-9622(82)70014-3subject
Has Abstractpub_date
1982-02-01 00:00:00pages
215-23issue
2eissn
0190-9622issn
1097-6787pii
S0190-9622(82)70014-3journal_volume
6pub_type
杂志文章abstract：:Infantile leukemia accounts for only 3% of childhood leukemia. Leukemia cutis occurs in 25% to 30% of infants with congenital leukemia and is more frequently associated with acute myeloid leukemia than with acute lymphoblastic leukemia. We describe an infant in whom hyperpigmented macules that developed when the patie...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(07)80012-0
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:Although rare in the general population, highly penetrant germline mutations in CDKN2A are responsible for 5%-40% of melanoma cases reported in melanoma-prone families. We sought to determine whether MELPREDICT was generalizable to a global series of families with melanoma and whether performance improvement...
journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
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journal_title：Journal of the American Academy of Dermatology
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更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...
journal_title：Journal of the American Academy of Dermatology
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更新日期：2020-01-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(90)70190-s
更新日期：1990-07-01 00:00:00
abstract：:The epidermal nevus syndrome is characterized by the association of epidermal nevi with abnormalities of the skin, skeletal system, central nervous system, eyes, and cardiovascular system, as well as with malignant conditions. We describe a 2-year-old girl with an extensive epidermal nevus involving the left side of t...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(96)90098-5
更新日期：1996-11-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
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更新日期：2001-01-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章
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更新日期：1989-10-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
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更新日期：2020-08-12 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
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更新日期：1990-08-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(87)70099-1
更新日期：1987-04-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
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更新日期：1990-03-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(84)70033-8
更新日期：1984-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2003.07.012
更新日期：2004-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of the American Academy of Dermatology
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journal_title：Journal of the American Academy of Dermatology
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更新日期：1998-04-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
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更新日期：1990-05-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
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更新日期：1993-07-01 00:00:00
abstract：:Multiple endocrine neoplasia type 1 (MEN 1) predisposes affected persons to neoplasms of the parathyroid glands, the endocrine pancreas, the anterior pituitary, and the duodenum. We report the first case of adult-onset multiple angiofibromas of the central face associated with MEN 1. Seven siblings also developed adul...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(99)70353-1
更新日期：1999-11-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
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abstract：BACKGROUND:Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious. OBJECTIVE:To evaluate the comparative efficacy and safety of antiscabietic agents. METHODS:A systematic review of randomized controlled trials was conducted. Direct and network meta-analyses were applied to...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,meta分析
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更新日期：2019-05-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
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更新日期：1988-08-01 00:00:00
abstract：:Significant progress has been made in skin replacement options in the past several decades. Although initially various materials have been used mainly for burn coverage, their application to dermatologic practice has increased significantly. We review the research, progress, and other aspects of wound coverage with sy...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/0190-9622(90)70279-q
更新日期：1990-10-01 00:00:00
abstract：:Cicatricial pemphigoid is a chronic, presumed autoimmune, blistering disease of the mucous membranes and occasionally of the skin. The characteristic feature is scarring at the sites of healing. We report the use of thalidomide as a therapeutic agent to control previously resistant disease. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1067/mjd.2002.109255
更新日期：2002-08-01 00:00:00
abstract：:Betel is a compound of natural substances chewed for its psychostimulating effects. Betel is composed of the nut of the areca palm (Areca catechu), the leaf of the betel pepper (Piper betle), and lime (calcium hydroxide). Approximately 200 million persons chew betel regularly throughout the western Pacific basin and s...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(98)70543-2
更新日期：1998-01-01 00:00:00
