Adult-onset angiofibroma and multiple endocrine neoplasia type I.

Abstract:

:Multiple endocrine neoplasia type 1 (MEN 1) predisposes affected persons to neoplasms of the parathyroid glands, the endocrine pancreas, the anterior pituitary, and the duodenum. We report the first case of adult-onset multiple angiofibromas of the central face associated with MEN 1. Seven siblings also developed adult-onset angiofibromas, none with evidence of tuberous sclerosis. Basic fibroblast growth factor (BFGF) is elevated in many patients with MEN 1 and may play a pathogenetic role.

journal_name

J Am Acad Dermatol

authors

Hoang-Xuan T,Steger JW

doi

10.1016/s0190-9622(99)70353-1

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

890-2

issue

5 Pt 2

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(99)70353-1

journal_volume

41

pub_type

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