Hypomelanosis of Ito. Report of a case and review of the literature.

abstract：:The literature concerning the use and possible mode of action of thalidomide in reactional lepromatous leprosy and in various other conditions is reviewed. Although it has no action against the leprosy bacillus, its value in the treatment of the adverse reactions in this type of leprosy is well established, many lepro...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,McDougall AC

更新日期：1982-09-01 00:00:00

abstract：:The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is a rare disorder caused by mutations of the FOXP3 gene. The FOXP3 gene encodes a DNA-binding protein of the forkhead/winged-helix family and is the central controller of the development of CD4+CD25+ regulatory T cells. CD4+CD25+ regu...

journal_title：Journal of the American Academy of Dermatology

authors： McGinness JL,Bivens MM,Greer KE,Patterson JW,Saulsbury FT

更新日期：2006-07-01 00:00:00

abstract：:Sunscreen preparations can reduce the erythemogenic ( sunburning ) effects of solar ultraviolet radiation (UVR). Less is known about the ability of sunscreens to protect against other forms of UVR-induced damage. This study was designed to yield data on epidermal cell damage at UVR doses sufficient to provoke vascular...

journal_title：Journal of the American Academy of Dermatology

authors： Sambuco CP,Forbes PD,Davies RE,Urbach F

更新日期：1984-05-01 00:00:00

abstract：:A unique, progressive syndrome of muscle weakness, ascending telangiectasia, and venous ectasia of the legs developed in a 55-year-old woman with autoimmune thyroiditis. Myopathy was documented by electromyography and electron microscopy. Her constellation of findings is considered to be of autoimmune origin. Treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Shelley WB,Shelley ED

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis (ACD) to optical brighteners and enzymes in laundry detergents was the focus of numerous reports in the early 1970s. Subsequently, there has been little published on the incidence of allergic reactions to chemicals in laundry detergents. Nonetheless, consumers and physicians conti...

journal_title：Journal of the American Academy of Dermatology

authors： Belsito DV,Fransway AF,Fowler JF Jr,Sherertz EF,Maibach HI,Mark JG Jr,Mathias CG,Rietschel RL,Storrs FJ,Nethercott JR

更新日期：2002-02-01 00:00:00

abstract：:The Fourth Annual Symposium on Hidradenitis Suppurativa (SHSA) took place on November 1-3, 2019, at the Westin Book Cadillac Hotel in Detroit, Michigan. This symposium was a joint meeting of the US Hidradenitis Suppurativa Foundation and the Canadian Hidradenitis Suppurativa Foundation. This cross-disciplinary meeting...

journal_title：Journal of the American Academy of Dermatology

authors： Narla S,Price KN,Sachdeva M,Shah M,Shi V,Hamzavi I,Alavi A,Lowes MA

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Antidrug antibodies (ADAs) may change pharmacokinetic or pharmacodynamic profiles of biologic therapies, potentially decreasing efficacy. OBJECTIVE:To evaluate the potential effects of brodalumab immunogenicity on safety, efficacy, and retreatment. METHODS:Data from 1 phase 2 and 3 phase 3 studies of broda...

journal_title：Journal of the American Academy of Dermatology

authors： Bagel J,Lebwohl M,Israel RJ,Jacobson A

更新日期：2020-02-01 00:00:00

abstract：:Five of seven patients with acquired immunodeficiency syndrome (AIDS) who had pruritus and a chronic, nonspecific-appearing skin eruption had increased antibody titers to antigens in the salivary glands of Aedes taeniorhynchus, a salt marsh mosquito common to South Florida. We hypothesize that the pruritus and skin le...

journal_title：Journal of the American Academy of Dermatology

authors： Penneys NS,Nayar JK,Bernstein H,Knight JW

更新日期：1989-08-01 00:00:00

abstract：:Angioma serpiginosum is a rare condition that involves both the proliferation and dilatation of superficial blood vessels in the skin. It classically begins in childhood, is more common in females, and is asymptomatic. Typical lesions appear on the extremities and are often asymmetric. We report a case of angioma serp...

journal_title：Journal of the American Academy of Dermatology

authors： Katta R,Wagner A

更新日期：2000-02-01 00:00:00

abstract：:The main limitation for the use of direct immunofluorescence in skin biopsies was the necessity for frozen tissue. In 1973 Michel et al reported use of a liquid fixative, consisting of ammonium sulfate, N-ethyl-maleimide, magnesium sulfate, and potassium citrate, for handling skin biopsy specimens. The present study i...

journal_title：Journal of the American Academy of Dermatology

authors： Niedecken HW,Lange CE

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Actinic keratosis (AK) is the earliest clinical manifestation of squamous cell carcinoma. Metastatic SCC causes the majority of the 1300 to 2300 deaths attributed to nonmelanoma skin cancer in the United States each year. Recent studies have shown that intralesional administration of interferon can be used s...

journal_title：Journal of the American Academy of Dermatology

authors： Persaud AN,Shamuelova E,Sherer D,Lou W,Singer G,Cervera C,Lamba S,Lebwohl MG

更新日期：2002-10-01 00:00:00

abstract：:Removal of Norplant contraceptive implants may be rendered difficult by the size of the capsules and variations in insertion technique. In the standard removal technique, a single transverse incision is made close to and below the distal ends of the capsules, and a mosquito forceps is used for extraction. Described,...

journal_title：Journal of the American Academy of Dermatology

authors： Lam M,Tope WD

更新日期：1997-11-01 00:00:00

abstract：:The clinical and histologic spectrum of melanotic macule of the nail unit is examined and the differences in the clinical appearance of longitudinal melanochychia caused by melanotic macule and by other kinds of proliferations of melanocytes are assessed. We observed that the clinical appearance of the pigmented band ...

journal_title：Journal of the American Academy of Dermatology

authors： Husain S,Scher RK,Silvers DN,Ackerman AB

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Cyclosporine is effective in psoriasis, but long-term continuous therapy may be limited by renal impairment and hypertension. Intermittent short courses of treatment should minimize side effects and improve the risk-benefit ratio. OBJECTIVE:Our purpose was to assess the long-term efficacy and safety of inte...

journal_title：Journal of the American Academy of Dermatology

authors： Ho VC,Griffiths CE,Berth-Jones J,Papp KA,Vanaclocha F,Dauden E,Beard A,Puvanarajan L,Paul C

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:It is important for dermatologists and other physicians in refugee-receiving countries to acquire knowledge of forensic dermatology to identify lesions from torture. OBJECTIVE:Review forensic dermatology in cases of torture. RESULTS:In providing medical assessment and care to refugees and migrants, chronic...

journal_title：Journal of the American Academy of Dermatology

authors： Deps PD,Aborghetti HP,Zambon TL,Costa VC,Dadalto Dos Santos J,Collin SM,Charlier P

更新日期：2020-09-15 00:00:00

abstract：:The tumor-promoting phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) causes a dose-dependent induction (up to 300-fold) of ornithine decarboxylase activity in the epidermis of intact mice within 5 hours after the application to the skin of from 1 to 10 nmoles of the ester in 0.2 ml of acetone. Enzyme activity...

journal_title：Journal of the American Academy of Dermatology

authors： Boutwell RK

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Degos disease or malignant atrophic papulosis is a rare occlusive vasculopathic disease characterized by pathognomonic cutaneous lesions and frequently fatal systemic involvement. The etiology of malignant atrophic papulosis remains unclear, and there is currently no effective treatment for malignant atrophi...

journal_title：Journal of the American Academy of Dermatology

authors： Meephansan J,Komine M,Hosoda S,Tsuda H,Karakawa M,Murata S,Demitsu T,Ohtsuki M

更新日期：2013-01-01 00:00:00

abstract：:Five patients are described with the clinical and histopathologic picture, including flame figures, of eosinophilic cellulitis (Wells' syndrome). Two of them had documented tick bites in the center of these expanding annular lesions, and the histologic picture showed the diagnostic flame figures of Wells' syndrome (eo...

journal_title：Journal of the American Academy of Dermatology

authors： Schorr WF,Tauscheck AL,Dickson KB,Melski JW

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Topical corticosteroids alone or in combination with other therapies are widely used to treat mycosis fungoides (MF), but data on response rates to their use as monotherapy in MF are limited. OBJECTIVE:To evaluate the efficacy of topical corticosteroid monotherapy in MF; compare sex, age, stage distribution...

journal_title：Journal of the American Academy of Dermatology

authors： Kartan S,Shalabi D,O'Donnell M,Alpdogan SO,Sahu J,Shi W,Porcu P,Cha J,Nikbakht N

更新日期：2020-05-16 00:00:00

abstract：:Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised individuals who have higher risk of malignant transformation and are more difficult to treat. This is part I of a two-p...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Kovarik CL

更新日期：2012-06-01 00:00:00

abstract：:Apoptosis, a genetically encoded program that results in cell death, represents a fundamental biologic concept that has relevance to a wide range of dermatologic processes. This review discusses the basic biology of apoptosis and its relevance to cutaneous disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Raskin CA

更新日期：1997-06-01 00:00:00

abstract：:Histoplasma capsulatum and Trichosporon inkin may cause disseminated disease in immunocompromised patients. Disseminated T inkin, the causative agent of white piedra, is rare and difficult to diagnose. We report the case of a 28 year-old man with newly diagnosed HIV infection who developed asymptomatic lesions on his ...

journal_title：Journal of the American Academy of Dermatology

authors： David C,Martin DB,Deng A,Cooper JZ

更新日期：2008-08-01 00:00:00

abstract：:In a pilot study the therapeutic effect and side effect profile of low-dose interferon alfa-2b in combination with a retinoid for the treatment of cutaneous T cell lymphoma were evaluated. Seven patients (four women, three men) with histologically confirmed cutaneous T cell lymphoma were included. Four patients had re...

journal_title：Journal of the American Academy of Dermatology

authors： Knobler RM,Trautinger F,Radaszkiewicz T,Kokoschka EM,Micksche M

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：:We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils...

journal_title：Journal of the American Academy of Dermatology

authors： Kuan YZ,Chiou HT,Chang HC,Chan HL,Kuo TT

更新日期：1990-05-01 00:00:00

abstract：:A survey was made of the sterile technique practices of dermatologists interested in dermatologic surgery. The steam autoclave is the most popular method for sterilizing surgical instruments. Dry heat sterilization is often used, as is cold, chemical sterilization. The most popular agent for chemical sterilization con...

journal_title：Journal of the American Academy of Dermatology

authors： Sebben JE

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Reducing people's exposure to ultraviolet radiation is the primary strategy for skin cancer prevention. OBJECTIVE:We sought to provide comprehensive national data on preventive behaviors and risk assessment for Australia. METHODS:A national survey was conducted in summer 2003-2004. In 8 weekly cross-sectio...

journal_title：Journal of the American Academy of Dermatology

authors： Dobbinson S,Wakefield M,Hill D,Girgis A,Aitken JF,Beckmann K,Reeder AI,Herd N,Fairthorne A,Bowles KA

更新日期：2008-10-01 00:00:00

abstract：:We present a case of cutaneous infection due to Cladophialophora bantiana, an agent of phaeohyphomycosis. The patient developed a nodule with pustule formation on the dorsum of the left hand; no trauma was reported. The lesion was successfully treated with itraconazole and surgical excision. Histopathologically, there...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Warren NG,Kelly LW

更新日期：1999-02-01 00:00:00

abstract：:Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of po...

journal_title：Journal of the American Academy of Dermatology

authors： Guin JD,Gillis WT,Beaman JH

更新日期：1981-01-01 00:00:00

abstract：:Atenolol is a beta-blocker commonly used for treating hypertension. It can induce various kinds of adverse side effects, including psoriasiform skin eruptions, skin necrosis, vasculitis, and (rarely) drug-induced connective tissue disease. We encountered a patient receiving atenolol for his hypertension for 3 years wh...

journal_title：Journal of the American Academy of Dermatology

authors： McGuiness M,Frye RA,Deng JS

更新日期：1997-08-01 00:00:00