Elevation of fasting serum lipids in patients treated with low-dose cyclosporine for severe plaque-type psoriasis. An assessment of clinical significance when viewed as a risk factor for cardiovascular disease.

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：:The American Academy of Dermatology's national program of Melanoma/Skin Cancer Detection and Prevention, developed in response to the rising incidence of invasive melanoma in the United States, has annually produced extensive print, radio, and television coverage about performing skin self-examination (SSE). This stud...

journal_title：Journal of the American Academy of Dermatology

authors： Robinson JK,Rigel DS,Amonette RA

更新日期：1998-05-01 00:00:00

abstract：:The IFAP syndrome is characterized by the congenital onset of ichthyosis follicularis, absence of hair, and photophobia. A limited number of patients with the disorder have been described, and X-linked recessive inheritance has been proposed. Two unrelated female patients with a complete IFAP syndrome are reported. Bo...

journal_title：Journal of the American Academy of Dermatology

authors： Cambiaghi S,Barbareschi M,Tadini G

更新日期：2002-05-01 00:00:00

abstract：:Scleromyxedema is a rare cutaneous disease with occasional systemic involvement and characteristic poor response to treatment. A case of scleromyxedema associated with renal scleroderma and acute psychosis is presented, along with a review of treatment and associated internal disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kantor GR,Bergfeld WF,Katzin WE,Reynolds OD,Biscardi AP,Lobur DM,Box TA,Schreiber MJ Jr,Ratliff NB

更新日期：1986-05-01 00:00:00

abstract：:Isotretinoin has demonstrated efficacy in a wide range of disorders. The beneficial effects of the drug, however, are limited by its adverse effects on the bone. Children exposed to high doses are at risk for premature epiphyseal closure, while adults on long-term therapy have an increased tendency to develop hypersto...

journal_title：Journal of the American Academy of Dermatology

authors： DiGiovanna JJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Despite recommendations to limit the use of oral antibiotics and increasing support for hormonal agents in the treatment of acne, it is unclear whether there have been any significant changes in practice patterns. OBJECTIVE:To characterize changes in prescribing behavior for systemic agents in the treatment...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,James WD,Margolis DJ

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：:Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA

更新日期：1991-08-01 00:00:00

abstract：:Pruritic folliculitis of pregnancy is a rare pregnancy dermatosis that clears spontaneously in the postpartum period. We describe a patient with characteristic clinical and histopathologic features of this dermatosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kroumpouzos G,Cohen LM

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Early specialist evaluation during rapid proliferative growth of complicated infantile hemangiomas (IH) is crucial. Health disparities and barriers of access-to-care for children with IH have not been examined. OBJECTIVE:Investigate whether socioeconomic status (SES) is associated with age at subspecialist ...

journal_title：Journal of the American Academy of Dermatology

authors： Lie E,Psoter KJ,Püttgen KB

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：:UVB irradiation is known to produce DNA damage at mutation hotspots in the p53 tumor suppressor gene, leading to the development of skin cancers. Mutations in the PTCH tumor suppressor gene, which is known to be responsible for the development of nevoid basal cell carcinoma syndrome, have also been identified in spora...

journal_title：Journal of the American Academy of Dermatology

authors： Ratner D,Peacocke M,Zhang H,Ping XL,Tsou HC

更新日期：2001-02-01 00:00:00

abstract：:Several infections contracted in utero result in similar physical and laboratory findings during the neonatal period; the TORCH syndrome encompasses such patients. Skin lesions are a frequent finding and the dermatologist may play an important role in the early evaluation of these infants. In this review we discuss et...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Arndt KA

更新日期：1985-04-01 00:00:00

abstract：:Five patients are described with the clinical and histopathologic picture, including flame figures, of eosinophilic cellulitis (Wells' syndrome). Two of them had documented tick bites in the center of these expanding annular lesions, and the histologic picture showed the diagnostic flame figures of Wells' syndrome (eo...

journal_title：Journal of the American Academy of Dermatology

authors： Schorr WF,Tauscheck AL,Dickson KB,Melski JW

更新日期：1984-12-01 00:00:00

abstract：:Forty cases of lentigo maligna (LM) and lentigo maligna melanoma (LMM) treated by conventional fractionated radiotherapy are reviewed. Fourteen of seventeen LM patients are alive and well 4 months to 5 years following irradiation, one patient died of intercurrent disease without recurrence, and two had residual or rec...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood AR

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Dermoscopy improves the recognition of melanoma and Spitz nevus but occasionally melanoma may exhibit a symmetric pattern mimicking Spitz nevus. OBJECTIVE:We sought to investigate the likelihood of finding melanoma when excising a symmetric Spitzoid-looking lesion in patients aged 12 years or older. METHOD...

journal_title：Journal of the American Academy of Dermatology

authors： Lallas A,Moscarella E,Longo C,Kyrgidis A,de Mestier Y,Vale G,Guida S,Pellacani G,Argenziano G

更新日期：2015-01-01 00:00:00

abstract：:Malignant myxoid melanoma (MMM) is a rarely reported variant of malignant melanoma, which can often be confused with other mucin-containing neoplasms. A retrospective study of 3 cases of MMM and a review of the English-language literature was performed. MMM affects an older population and is frequently misdiagnosed. T...

journal_title：Journal of the American Academy of Dermatology

authors： Patel P,Levin K,Waltz K,Helm KF

更新日期：2002-02-01 00:00:00

abstract：:Pyoderma gangrenosum, severe acne, and suppurative hidradenitis (PASH) syndrome can prove refractory to treatment and is characterized by relapses and recurrences. The combination of antibiotic therapy and surgery can produce success in the management of the syndrome. Acute treatment is required, but maintenance thera...

journal_title：Journal of the American Academy of Dermatology

authors： Join-Lambert O,Duchatelet S,Delage M,Miskinyte S,Coignard H,Lemarchand N,Alemy-Carreau M,Lortholary O,Nassif X,Hovnanian A,Nassif A

更新日期：2015-11-01 00:00:00

abstract：:The most common active ingredient in hair coloring is para-phenylenediamine (PPDA), which can produce contact dermatitis, particularly in persons who dye their scalp hair and in hairdressers. We have identified another group of patients also at risk, namely men from Arab countries, who commonly grow beards and dye the...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu TS,Davis MD,el-Azhary R,Corbett JF,Gibson LE

更新日期：2001-05-01 00:00:00

abstract：:Sixty-eight cutaneous squamous cell neoplasms (in situ and invasive) and 26 basal cell carcinomas from 89 patients were analyzed for DNA sequences homologous to the human papillomavirus (HPV) types found predominantly in the genital tract. Thirty-six (53%) of the squamous cell neoplasms contained HPV DNA as detected b...

journal_title：Journal of the American Academy of Dermatology

authors： Eliezri YD,Silverstein SJ,Nuovo GJ

更新日期：1990-11-01 00:00:00

abstract：:A unique, progressive syndrome of muscle weakness, ascending telangiectasia, and venous ectasia of the legs developed in a 55-year-old woman with autoimmune thyroiditis. Myopathy was documented by electromyography and electron microscopy. Her constellation of findings is considered to be of autoimmune origin. Treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Shelley WB,Shelley ED

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The risk of acquiring Lyme disease has been evaluated by xenodiagnostic procedures with laboratory strains of Borrelia burgdorferi and laboratory-reared Ixodes ticks, or by clinical trials in which diagnosis was based on clinical findings, culture, or serologic tests. OBJECTIVE:Our purpose was to determine ...

journal_title：Journal of the American Academy of Dermatology

authors： Berger BW,Johnson RC,Kodner C,Coleman L

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Methotrexate has been used both as monotherapy and as an adjunct to corticosteroids in the treatment of alopecia areata (AA), though there exists a paucity of definitive evidence and guidelines in this setting. OBJECTIVES:To 1) determine the efficacy and risks associated with methotrexate therapy for AA, 2)...

journal_title：Journal of the American Academy of Dermatology

authors： Phan K,Ramachandran V,Sebaratnam DF

更新日期：2019-01-01 00:00:00

abstract：UNLABELLED:Mycophenolate mofetil (MMF) is the prodrug of mycophenolic acid (MPA), a medication used to treat psoriasis in the 1970s until side effects and the concern of carcinogenesis led to its discontinuation. The prodrug, MMF, emerged decades later in the transplant field. Dermatologists have since used MMF off-lab...

journal_title：Journal of the American Academy of Dermatology

authors： Orvis AK,Wesson SK,Breza TS Jr,Church AA,Mitchell CL,Watkins SW

更新日期：2009-02-01 00:00:00

abstract：:We report the case of an otherwise healthy 37-year-old man who had had bilateral enucleation during early childhood for bilateral retinoblastomas, in addition to two cutaneous melanomas (the first appearing at age 27 years). He also had dysplastic melanocytic nevi and a history of cutaneous melanoma in his mother. Ret...

journal_title：Journal of the American Academy of Dermatology

authors： Albert LS,Sober AJ,Rhodes AR

更新日期：1990-11-01 00:00:00

abstract：:We present two patients who developed granuloma annulare in the scars from previous herpes zoster. The development of granuloma annulare in herpes zoster scars may represent an atypical delayed hypersensitivity immune reaction to herpes zoster/varicella virus antigen(s) or a tissue antigen altered by the virus. ...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Fox BJ,Albert HL

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Methyldibromoglutaronitrile (MDGN) is a component of Euxyl K400, a preservative used in many skin care products in Europe. MDGN has been used in skin care products in the United States for the last 5 years. Contact allergy from MDGN has been reported from Europe. OBJECTIVE:The purpose of this study was to d...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson JM,Fowler JF

更新日期：1998-06-01 00:00:00

abstract：:Chemical peeling, or chemexfoliation, has been used for centuries to improve signs of ultraviolet light-induced sun damage. Over the last 30 years, the science behind chemical peeling has evolved, increasing our understanding of the role of peeling ingredients and treatment indications. The depth of peels is directly ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee KC,Wambier CG,Soon SL,Sterling JB,Landau M,Rullan P,Brody HJ,International Peeling Society.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Rituximab (RTX) is an effective therapy for patients with pemphigus; however, the therapy does not prevent relapse. OBJECTIVES:To compare early relapsing patients (before 12 months) and late relapsing patients (after 24 months) following RTX therapy. METHOD:In this prospective study, 19 patients were enrol...

journal_title：Journal of the American Academy of Dermatology

authors： Saleh MA

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Although there is increased understanding of the alopecia areata (AA) pathogenesis based on studies in scalp tissues, little is known about its systemic profile. OBJECTIVE:To evaluate the blood proteomic signature of AA and determine biomarkers associated with increased disease severity. METHODS:In a cross...

journal_title：Journal of the American Academy of Dermatology

authors： Glickman JW,Dubin C,Renert-Yuval Y,Dahabreh D,Kimmel GW,Auyeung K,Estrada YD,Singer G,Krueger JG,Pavel AB,Guttman-Yassky E

更新日期：2021-02-01 00:00:00