Response to topical corticosteroid monotherapy in mycosis fungoides.

abstract：BACKGROUND:Safe and efficacious topical treatments are needed for atopic dermatitis (AD). OBJECTIVE:We assessed the safety and efficacy of tapinarof cream (2 concentrations and 2 application frequencies) in patients with AD. METHODS:A double-blind, vehicle-controlled, randomized, 6-arm trial (1:1:1:1:1:1) in patients...

journal_title：Journal of the American Academy of Dermatology

authors： Peppers J,Paller AS,Maeda-Chubachi T,Wu S,Robbins K,Gallagher K,Kraus JE

更新日期：2019-01-01 00:00:00

abstract：UNLABELLED:Skin cancer is the most common cancer in human beings. The increased incidence of skin cancer has brought much attention to the process by which these tumors develop and how they can be prevented. Efforts have been made to educate the public about the importance of protecting skin from excessive ultraviolet ...

journal_title：Journal of the American Academy of Dermatology

authors： Wright TI,Spencer JM,Flowers FP

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Hypopigmented macules have been described infrequently as a presenting form of mycosis fungoides (MF). OBJECTIVE:This study was designed to clarify general characteristics of a hypopigmented MF variant. METHODS:Seven new cases were investigated with the use of descriptive epidemiology techniques. Demograph...

journal_title：Journal of the American Academy of Dermatology

authors： Lambroza E,Cohen SR,Phelps R,Lebwohl M,Braverman IM,DiCostanzo D

更新日期：1995-06-01 00:00:00

abstract：:A new disorder of the hair follicle is described that leads to increased fragility of the shaft. Light microscopic studies of hair follicles revealed disturbances of keratinization in the shafts that are very likely responsible for the breakage. The most consistent change seen by transmission electron microscopy was i...

journal_title：Journal of the American Academy of Dermatology

authors： Birnbaum PS,Baden HP,Bronstein BR,Nakagawa H,Hori Y

更新日期：1986-07-01 00:00:00

abstract：:Part 3 of this 4-part continuing medical education series reviews several important infectious complications of corticosteroid use, including a focus on pneumocystis pneumonia (PCP) prophylaxis, tuberculosis, viral hepatitis, and other infections, followed by a discussion of vaccination recommendations in immunosuppre...

journal_title：Journal of the American Academy of Dermatology

authors： Caplan A,Fett N,Rosenbach M,Werth VP,Micheletti RG

更新日期：2017-02-01 00:00:00

abstract：:A patient with a 10-year history of an acquired, scarring bullous eruption localized to the anterior surfaces of the lower extremities is described. Clinical, histologic, and electron microscopic features of an acquired form of epidermolysis bullosa are shown to occur in the absence of immune deposits, a finding not p...

journal_title：Journal of the American Academy of Dermatology

authors： Unis ME,Pfau RG,Patel H,Takahashi Y,Anhalt GJ

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Electronic claims and medical record databases are increasingly used for observational studies of psoriasis. The purpose of this study was to assess the validity of psoriasis diagnostic codes in an electronic database. METHODS:This study was performed in a population-based setting in Olmsted County, Minneso...

journal_title：Journal of the American Academy of Dermatology

authors： Icen M,Crowson CS,McEvoy MT,Gabriel SE,Maradit Kremers H

更新日期：2008-12-01 00:00:00

abstract：:Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch ...

journal_title：Journal of the American Academy of Dermatology

authors： Neale H,Garza-Mayers AC,Tam I,Yu J

更新日期：2021-02-01 00:00:00

abstract：:Myospherulosis is an uncommon subcutaneous disorder believed initially to be caused by an endosporulating fungus. Recently investigators have disproved an infectious cause and have shown that the disease represents an alteration in red blood cells, usually produced by petrolatum or lanolin, with an accompanying foreig...

journal_title：Journal of the American Academy of Dermatology

authors： Waldman JS,Barr RJ,Espinoza FP,Simmons GE

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00

abstract：:High frequency of B-RAF gene mutations has recently been identified in benign melanocytic nevi and melanoma. This review focuses on clinical studies that evaluate the role of B-RAF in melanocytic neoplasia. ...

journal_title：Journal of the American Academy of Dermatology

authors： Gill M,Celebi JT

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Isotretinoin treatment is frequently associated with reversible, dose-related side effects. Recent studies claimed that combining vitamin E with high-dose isotretinoin ameliorated isotretinoin-induced side effects. OBJECTIVE:The purpose of this double-blind, randomized study was to determine the effects of ...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Gottlieb AB,Jones T,Koo JY,Leyden JJ,Lucky A,Pappas AA,McLane J,Leach EE

更新日期：2000-11-01 00:00:00

abstract：:A cutaneous and soft tissue reaction that resulted from a broken thermometer inside the mouth of a 10-year-old boy is described. Metallic mercury globules and glass pieces were identified in the excised tissue. On histologic examination, a zone of necrosis, polymorphonuclear leukocytes, macrophages, and multinucleated...

journal_title：Journal of the American Academy of Dermatology

authors： Sau P,Solivan G,Johnson FB

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Recombinant human platelet derived growth factor-BB gel (PDGF gel) has been shown to be effective in the treatment of diabetic neuropathic ulcers. It is also being used off-label to speed wound healing of flaps, grafts, and wounds from Mohs micrographic surgery. OBJECTIVE:The purpose of the study was to com...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen MA,Eaglstein WH

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is caused by different species of Leishmania and transmitted by the bite of infected sand flies. It is a health problem in many countries. OBJECTIVE:This study was performed to assess the evidence for the efficacy of different therapeutic modalities for acute Old World CL, which...

journal_title：Journal of the American Academy of Dermatology

authors： Khatami A,Firooz A,Gorouhi F,Dowlati Y

更新日期：2007-08-01 00:00:00

abstract：:Treatment of cicatricial pemphigoid is a problem because patients afflicted are elderly, the disease is chronic, systemic agents required for control are potentially toxic (particularly to older patients), and the disease is often in an advanced stage when the diagnosis is established and requires aggressive therapy f...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers RS 3rd,Seehafer JR,Perry HO

更新日期：1982-02-01 00:00:00

abstract：:We describe a 21-year-old male patient with linear extragenital lichen sclerosus. The lesions are confined to the left side of his body and consist of 3 long bands running along the left leg and several patchy and linear lesions on the left side of his trunk. An associated finding is a smaller diameter of the distal p...

journal_title：Journal of the American Academy of Dermatology

authors： Pavlović MD

更新日期：2004-03-01 00:00:00

abstract：:Sulfur is a time-honored therapeutic agent useful in a variety of dermatologic disorders. Its keratolytic action is due to formation of hydrogen sulfide through a reaction that depends upon direct interaction between sulfur particles and keratinocytes. The smaller the particle size, the greater the degree of such inte...

journal_title：Journal of the American Academy of Dermatology

authors： Lin AN,Reimer RJ,Carter DM

更新日期：1988-03-01 00:00:00

abstract：:We describe the clinical and biochemical features of an infant with marked transient porphyrinemia in whom blistering developed while the infant was undergoing phototherapy for severe Rh isoimmunization. The cause of the transient porphyrinemia was likely to be multifactorial--abnormal porphyrin metabolism or accumula...

journal_title：Journal of the American Academy of Dermatology

authors： Mallon E,Wojnarowska F,Hope P,Elder G

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:A new anticancer therapy, electrochemotherapy (ECT), has been introduced that entails exposing cancerous tissues to short pulses of electricity during chemotherapy. This enhances cell membrane permeability and has been shown to have potent antitumor effects in vitro in animal models and in several clinical t...

journal_title：Journal of the American Academy of Dermatology

authors： Glass LF,Jaroszeski M,Gilbert R,Reintgen DS,Heller R

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The association of atopic dermatitis (AD) with other allergic diseases has been extensively studied; however, there is a lack of reports focusing on long-term studies of the clinical and allergometric evaluations observed during the course of AD in respect to its evolution and association with allergic respo...

journal_title：Journal of the American Academy of Dermatology

authors： Ricci G,Patrizi A,Baldi E,Menna G,Tabanelli M,Masi M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) often displays extensive subclinical spread. Mohs micrographic surgery (MMS) has been proposed to help delineate the true histologic margin; however, visualizing atypical melanocytes on frozen section is challenging and often requires confirmatory permanent paraffin sections. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Kelley LC,Starkus L

更新日期：2002-01-01 00:00:00

abstract：:Tumid lupus erythematosus (LE) is a relatively rare and only recently recognized subset of chronic cutaneous lupus. We report a case occurring in a male with HIV infection whereby his rash was only unmasked by immune restoration following highly active antiretroviral therapy (HAART). The phenomenon of latent inflammat...

journal_title：Journal of the American Academy of Dermatology

authors： Chamberlain AJ,Hollowood K,Turner RJ,Byren I

更新日期：2004-11-01 00:00:00

abstract：:The American Academy of Dermatology's national program of Melanoma/Skin Cancer Detection and Prevention, developed in response to the rising incidence of invasive melanoma in the United States, has annually produced extensive print, radio, and television coverage about performing skin self-examination (SSE). This stud...

journal_title：Journal of the American Academy of Dermatology

authors： Robinson JK,Rigel DS,Amonette RA

更新日期：1998-05-01 00:00:00

abstract：:The clinical and histologic features of 26 cases of erythema induratum are reviewed. The characteristic cutaneous lesions on the legs of middle-aged women were violaceous, indurated nodules, 1 to 2 cm in diameter, which were painful, occasionally ulcerated, and could heal with scarring. The diagnosis was confirmed in ...

journal_title：Journal of the American Academy of Dermatology

authors： Rademaker M,Lowe DG,Munro DD

更新日期：1989-10-01 00:00:00

abstract：:We describe the case of a patient with both pemphigus vulgaris limited to the oral cavity and ocular cicatricial pemphigoid. The diagnoses were established by means of histopathologic examination and direct and indirect immunofluorescence studies and confirmed by immunoblot analysis of serum. Treatment with dapsone re...

journal_title：Journal of the American Academy of Dermatology

authors： Buhac J,Bhol K,Padilla T Jr,Foster CS,Ahmed AR

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...

journal_title：Journal of the American Academy of Dermatology

authors： Raffi J,Suresh R,Botto N,Murase JE

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：:Burow's wedge flap provides an excellent method for repair of wounds in or near the eyebrow. Advantages afforded by this technic in this context include ample flap elasticity and vascularization, versatility in dealing with wounds of varying dimension and location, and fewer incisions in comparison with the number nec...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley DE

更新日期：1985-02-01 00:00:00

abstract：:We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril. The cutaneous reaction remitted after withdrawal of captopril therapy. Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of th...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Potter TS,Fox JN

更新日期：1992-02-01 00:00:00