Linear extragenital lichen sclerosus with underlying bony atrophy.

abstract：BACKGROUND:We have observed, in patients undergoing high-dose PUVA treatment, a type of keratosis not previously described. The lesions usually occur on the sides of the palms or soles and are clinically distinct. They are generally painless and often go unnoticed by patients. OBJECTIVE:We sought to further characteri...

journal_title：Journal of the American Academy of Dermatology

authors： Turner RJ,Sviland L,Charlton F,Farr PM

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：:Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin. Recent advances in the immunopathogenesis and genetics of psoriasis have broadened our understanding of psoriasis. Psoriasis is now considered a systemic inflammatory condition analogous to other inflammatory immune disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kremers HM,McEvoy MT,Dann FJ,Gabriel SE

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Available information of the effect of sun exposure on the biologic activity and morphologic characteristics of nevi is based on a few cross-sectional studies. According to these, nevi excised in summer show a higher mitotic count, a greater extent of the junctional component, and more frequent regression an...

journal_title：Journal of the American Academy of Dermatology

authors： Stanganelli I,Rafanelli S,Bucchi L

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Unwanted tattoos are treated with Q-switched lasers. Despite a series of treatments, efficacy is limited. OBJECTIVE:We compared a single Q-switched laser treatment pass with 4 treatment passes separated by 20 minutes. METHODS:Eighteen tattoos on 12 adults were divided in half and randomized. One half recei...

journal_title：Journal of the American Academy of Dermatology

authors： Kossida T,Rigopoulos D,Katsambas A,Anderson RR

更新日期：2012-02-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:We report a case of fatal pancreatitis heralded by the presence of cutaneous panniculitis without abdominal pain or other stigmata of the disease. Although cutaneous fat necrosis has been associated with pancreatitis, it is unusual as the presenting complaint of this relatively common disease. In vitro evidence sugges...

journal_title：Journal of the American Academy of Dermatology

authors： Berman B,Conteas C,Smith B,Leong S,Hornbeck L 3rd

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:In response to the increasing rate of skin cancer, particularly melanoma in the United States, the Environmental Protection Agency, the National Weather Service, the Centers for Disease Control and Prevention, National Association of Physicians for the Environment, and the American Academy of Dermatology, de...

journal_title：Journal of the American Academy of Dermatology

authors： Geller AC,Hufford D,Miller DR,Sun T,Wyatt SW,Reilley B,Bewerse B,Lisco J,Brooks D,Grupenhoff J,Weary P,Lew RA,Koh HK

更新日期：1997-12-01 00:00:00

abstract：:The advent of new topical agents such as topical calcineurin inhibitors, as well as the reformulations of older agents in new vehicles, has broadened the treatment approaches to psoriasis and atopic dermatitis. The clinician must now consider additional novel physiologic pathways and mechanisms of action as well as ex...

journal_title：Journal of the American Academy of Dermatology

authors： Norris DA

更新日期：2005-07-01 00:00:00

abstract：:George Cheyne Shattuck's 1808 dissertation on structure and function of the skin is one of the earliest American writings on the topic of skin diseases. Although this essay contributed no important new observations, it does provide insight into the attitudes of American physicians in the post-Revolutionary War period ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine MC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

journal_title：Journal of the American Academy of Dermatology

authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

更新日期：2009-05-01 00:00:00

abstract：:Cutaneous T-cell lymphoma is a malignancy of T cells that express a clone-specific heterodimer T-cell receptor for antigen. The second recognized case of an epidermotropic malignancy of T-cells expressing gamma/delta T-cell receptor-expressing cells is reported. The immunophenotype of the malignant T-cells was CD3+, C...

journal_title：Journal of the American Academy of Dermatology

authors： Heald P,Buckley P,Gilliam A,Perez M,Knobler R,Kacinski B,Edelson R

更新日期：1992-05-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is an endogenous reactive oxygen species that contributes to oxidative stress directly as a molecular oxidant and indirectly through free radical generation. Topically applied 1% to 45% H2O2 can be used for a range of clinical purposes, which will be reviewed here in addition to its safety. In...

journal_title：Journal of the American Academy of Dermatology

authors： Murphy EC,Friedman AJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The cause of lichen sclerosus et atrophicus (LSA) is unknown, but on the penis it is associated with chronic occlusion, that is, phimosis. Microscopic changes of LSA were seen unexpectedly in two acrochordons. OBJECTIVE:Our purpose was to further characterize this phenomenon. METHODS:A total of 449 acrocho...

journal_title：Journal of the American Academy of Dermatology

authors： Weigand DA

更新日期：1993-05-01 00:00:00

abstract：:We discuss a metastatic dermatofibrosarcoma protuberans on the occiput of a 53-year-old man whose initial tumor appeared on his forehead 23 years previously. The pathology of the tumor that recurred at the initial site was fibrosarcomatous dermatofibrosarcoma protuberans, whereas the metastatic tumor was a pigmented d...

journal_title：Journal of the American Academy of Dermatology

authors： Kabumoto T,Fujiwara H,Kariya N,Tsujimoto T,Ito K,Ito M,Kobayashi H

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Dermatomyositis is associated with significant morbidity and occasional mortality. Currently there is no consensus on treatment for patients with dermatomyositis. OBJECTIVE:Our purpose was to review the clinical features and response to therapy of patients with dermatomyositis and compare these data with pr...

journal_title：Journal of the American Academy of Dermatology

authors： Dawkins MA,Jorizzo JL,Walker FO,Albertson D,Sinal SH,Hinds A

更新日期：1998-03-01 00:00:00

abstract：:We describe three unusual features of juvenile xanthogranuloma that were observed in three different children. We also describe the mixed and clustered forms of juvenile xanthogranuloma and a giant juvenile xanthogranuloma of the nose. ...

journal_title：Journal of the American Academy of Dermatology

authors： Caputo R,Grimalt R,Gelmetti C,Cottoni F

更新日期：1993-11-01 00:00:00

abstract：:In a randomized, double-blind comparative study 60 patients with severe, widespread psoriasis were treated either with photochemotherapy (PUVA) alone or in combination with acitretin. Forty-eight patients completed the study; of these, 25 received placebo combined with PUVA and 23 received acitretin with PUVA. Marked ...

journal_title：Journal of the American Academy of Dermatology

authors： Tanew A,Guggenbichler A,Hönigsmann H,Geiger JM,Fritsch P

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Patients with cutaneous lupus erythematosus (LE) and a history of disease- related photoaggravation, confirmed by phototesting, may not respond to photoprotection and/or medical intervention. Ultraviolet B-hardening therapy may improve tolerance for environmental ultraviolet radiation (UVR) in photosensitive...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders CJ,Lam HY,Bruijnzeel-Koomen CA,Sigurdsson V,van Weelden H

更新日期：2006-03-01 00:00:00

abstract：:Pyoderma gangrenosum (PG) has four distinctive clinical and histologic variants. Some have morphologic and histologic overlapping features with other reactive neutrophilic skin conditions. PG often occurs in association with a systemic disease, and the specific clinical features of the skin lesion may provide a clue t...

journal_title：Journal of the American Academy of Dermatology

authors： Powell FC,Su WP,Perry HO

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

journal_title：Journal of the American Academy of Dermatology

authors： Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

更新日期：2019-02-01 00:00:00

abstract：:We observed the course of development of porokeratosis stimulated by benzylhydrochlorothiazide (BHCTh) in normal-appearing skin of a patient with long-standing stable porokeratosis of Mibelli. A 72-year-old Japanese man had had porokeratosis of Mibelli for more than 50 years. During administration of BHCTh for 1 year ...

journal_title：Journal of the American Academy of Dermatology

authors： Inamoto N,Watanabe T,Nakamura K

更新日期：1984-08-01 00:00:00

abstract：:An intensely pruritic dermatosis that occurred in a woman during the third trimester of pregnancy is described. The clinical manifestations included red follicular papules symmetrically distributed on the skin of the forearms, abdomen, thighs, and legs. The histopathologic findings were not specific. However, immunopa...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,Ingber A,Hazaz B,David M,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The histopathological and clinical overlapping features between condyloma acuminata and bowenoid papulosis can present a diagnostic challenge and we sought to determine if immunochemistry can be helpful in this setting. OBJECTIVE:In this study, we evaluate the specificity and sensitivity of p16 immunohistoc...

journal_title：Journal of the American Academy of Dermatology

authors： Kazlouskaya V,Shustef E,Allam SH,Lal K,Elston D

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Topical corticosteroids alone or in combination with other therapies are widely used to treat mycosis fungoides (MF), but data on response rates to their use as monotherapy in MF are limited. OBJECTIVE:To evaluate the efficacy of topical corticosteroid monotherapy in MF; compare sex, age, stage distribution...

journal_title：Journal of the American Academy of Dermatology

authors： Kartan S,Shalabi D,O'Donnell M,Alpdogan SO,Sahu J,Shi W,Porcu P,Cha J,Nikbakht N

更新日期：2020-05-16 00:00:00

abstract：:A 36-year-old man had a high titer of antibody to Epstein-Barr virus (EBV) and recurrent necrotizing papules and nodules on his face and oral mucosa. The disease was diagnosed as CD3+4- 8+ large granular lymphocyte leukemia of T-cell origin. Southern blot analysis demonstrated that EBV DNA was present in CD8+ lymphocy...

journal_title：Journal of the American Academy of Dermatology

authors： Asada H,Okada N,Tei H,Yamamura T,Hashimoto K,Kondo K,Yamanishi K,Yoshikawa K

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the prevalence of IBD in HS patients is unknown. OBJECTIVE:To determine the prevalence of IBD in HS patients, and determine if patients with HS and IBD have a distinct HS ...

journal_title：Journal of the American Academy of Dermatology

authors： Deckers IE,Benhadou F,Koldijk MJ,Del Marmol V,Horváth B,Boer J,van der Zee HH,Prens EP

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The continuous increase in the US population older than 65 years and the chronic course of psoriasis make management of psoriasis in the elderly an important health care problem. OBJECTIVE:We sought to develop a treatment algorithm for patients with psoriasis who are older than 65 years. METHODS:A systemat...

journal_title：Journal of the American Academy of Dermatology

authors： Grozdev IS,Van Voorhees AS,Gottlieb AB,Hsu S,Lebwohl MG,Bebo BF Jr,Korman NJ,National Psoriasis Foundation.

更新日期：2011-09-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Mohs micrographic surgery (MMS) is an effective treatment for skin cancer. Until recently, it has been difficult to determine the percentage of skin cancers best treated with MMS. The appropriate-use criteria represents an opportunity to more accurately estimate this number. OBJECTIVE:We sought to apply the...

journal_title：Journal of the American Academy of Dermatology

authors： Blechman AB,Patterson JW,Russell MA

更新日期：2014-07-01 00:00:00