Abstract:
:We observed the course of development of porokeratosis stimulated by benzylhydrochlorothiazide (BHCTh) in normal-appearing skin of a patient with long-standing stable porokeratosis of Mibelli. A 72-year-old Japanese man had had porokeratosis of Mibelli for more than 50 years. During administration of BHCTh for 1 year because of his hypertension, a lichenoid drug eruption developed over the lesions of porokeratosis on the flexor aspects of his legs. Readministration of BHCTh by another physician for 6 months resulted in the occurrence of a similar drug eruption that converted into typical skin lesions of porokeratosis 8 weeks later. Serial microscopic examination suggested that BHCTh administration resulted in eosinophilic spongiosis and cornoid lamella formation, which developed into epidermal changes characteristic of porokeratosis.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Inamoto N,Watanabe T,Nakamura Kdoi
10.1016/s0190-9622(84)70172-1subject
Has Abstractpub_date
1984-08-01 00:00:00pages
357-61issue
2 Pt 2eissn
0190-9622issn
1097-6787pii
S0190-9622(84)70172-1journal_volume
11pub_type
杂志文章abstract:BACKGROUND:The use of cutaneous resurfacing lasers to treat rhytides is widely accepted. Several carbon dioxide lasers, many using fundamentally different technologies, are available. OBJECTIVE:The purpose of this study was to compare the results obtained and side effects after treating rhytides with 3 different carbo...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0190-9622(98)70002-7
更新日期:1998-10-01 00:00:00
abstract::This article reviews the definition of outcomes research. It explores the reasons that outcomes research should be conducted by practicing physicians in both university and private practice settings. Methods for outcomes research with examples relevant to dermatologists are detailed. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70164-1
更新日期:1998-06-01 00:00:00
abstract::Cutaneous multilobated T-cell lymphoma is an uncommon variant of skin-based peripheral T-cell lymphoma typically characterized by cutaneous nodules in elderly patients and a chronic clinical course. We report a case of the disease that led to the patient's death within 2 years after onset. This disease may be associat...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(91)70201-c
更新日期:1991-08-01 00:00:00
abstract::We describe a new family with the rare genodermatosis keratosis punctata palmo-plantaris Buschke-Fischer-Brauer (keratoma disseminatum). In all, 3 family members in 3 generations were affected, a pattern consistent with autosomal dominant inheritance. Clinical symptoms started in the third decade with disseminated, sm...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(03)00472-9
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2009.06.086
更新日期:2010-02-01 00:00:00
abstract::Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(87)70047-4
更新日期:1987-02-01 00:00:00
abstract:BACKGROUND:Keloid scars can itch and hurt, but little is known about the characteristics of these symptoms in keloids. Because itch and pain are carried by small nerve fibers, abnormal function of these fibers could be an explanation for such phenomena. OBJECTIVE:We sought to assess the characteristics of itch and pai...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2004.07.054
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:The formulation of topical dermatologic products must take into account efficacy, safety, and patient compliance. OBJECTIVE:We describe how an aqueous gel containing adapalene, a novel naphthoic acid derivative was selected for the topical treatment of acne. METHODS AND RESULTS:Dose selection was made usin...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)70055-0
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Embryofetal developmental toxicity associated with oral administration of vitamin A analogs has led to concern about risks from topical application. OBJECTIVE:This study was conducted to evaluate the potential developmental toxicity of tretinoin emollient cream when applied to the skin of pregnant New Zeala...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)70062-8
更新日期:1997-03-01 00:00:00
abstract::Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(83)70072-1
更新日期:1983-05-01 00:00:00
abstract::Cannabis arteritis is a serious peripheral vascular disease affecting young adults consuming cannabis. An increasing number of cases have been recently reported in Europe. The risk of amputation is high. Cannabis arteritis is often confused with atherosclerosis. We present a new case in which complete arterial revascu...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.04.024
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Lentigo maligna (LM) is a relatively common tumor with increasing prevalence and substantial morbidity. A variety of treatment modalities are available, though margin-control surgery offers the highest cure rate. We were interested in comparing long-term outcomes of Mohs micrographic surgery (MMS) versus sta...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.02.011
更新日期:2007-10-01 00:00:00
abstract::We report eight patients with ulcerative colitis who have subsequently developed pemphigoid. Four patients were investigated to determine the pattern of pemphigoid antibody staining on whole and chemically split skin and oral mucosa to distinguish between pemphigoid and epidermolysis bullosa acquisita. The findings we...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(88)70176-0
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND:CD2- CD4+ CD56+ lymphoid malignancy has been only rarely reported the last 5 years. It is characterized by a high incidence of cutaneous involvement, cytologically agranular cells, aggressive clinical course, and negative Epstein-Barr virus (EBV) involvement. OBSERVATION:We describe a Japanese patient with ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1067/mjd.2001.110897
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)80278-2
更新日期:1997-06-01 00:00:00
abstract:BACKGROUND:Hypopigmented macules have been described infrequently as a presenting form of mycosis fungoides (MF). OBJECTIVE:This study was designed to clarify general characteristics of a hypopigmented MF variant. METHODS:Seven new cases were investigated with the use of descriptive epidemiology techniques. Demograph...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(95)91337-8
更新日期:1995-06-01 00:00:00
abstract::A 7.3-year prospective study of 1,380 patients with psoriasis who were treated with oral methoxsalen (8-methoxypsoralen) and ultraviolet A photochemotherapy (PUVA) revealed that patients who continued on PUVA therapy used inpatient hospital treatment less than one fourth as often as those who had discontinued treatmen...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(86)70066-2
更新日期:1986-03-01 00:00:00
abstract::Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2012.05.036
更新日期:2012-12-01 00:00:00
abstract::Onycholysis (ONY) of the fingernails is a common disorder that is diagnosed with ease but often managed with great difficulty. The full spectrum of causes is broad and not always readily apparent. In this review, an approach to the evaluation and management of ONY is offered. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(85)70077-1
更新日期:1985-03-01 00:00:00
abstract::Scabies is an ectoparasitic dermatosis caused by Sarcoptes scabiei var. hominis and is a public health issue in all countries regardless of socioeconomic status. In high-income countries, delays in diagnosis can lead to institutional outbreaks; in low- and middle-income countries, poor access to health care contribute...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2019.05.109
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Conventional therapy of severe bullous pemphigoid (BP) relies on the use of high-dose systemic corticosteroids with or without adjuvants, notably immunosuppressive agents. This approach can result in debilitating and potentially fatal side effects, hence the need to explore alternative therapies. Intravenous...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,meta分析
doi:10.1067/mjd.2000.112288
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Junctional nevi are traditionally associated with children and younger patients. We noticed that these lesions are also often found in elderly patients. OBJECTIVE:We sought to determine if junctional nevi are found in all age groups. METHODS:All biopsy reports for junctional nevi for the year 2001 at the P...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2006.11.035
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:A wide array of miscellaneous agents is being studied for the treatment of atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents. OBJECTIVE:To review the known efficacy and safety to date for such agents being studied for the treatment of AD. METHODS:A nonsystematic review ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2017.12.024
更新日期:2018-03-01 00:00:00
abstract::A patient with acquired immunodeficiency syndrome presented with multiple pruritic papules and nodules over the trunk and extremities. Biopsy specimens from two of these lesions contained granules within abscesses of the papillary dermis. There were numerous gram-positive cocci within the granules. Culture of one lesi...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(87)80072-5
更新日期:1987-01-01 00:00:00
abstract::In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions....
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2005.05.014
更新日期:2005-10-01 00:00:00
abstract::The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(87)70195-9
更新日期:1987-08-01 00:00:00
abstract::Zinc is a trace element essential to the gastrointestinal, immune, integumentary, reproductive, and central nervous systems. Zinc deficiency is prevalent in many areas of the world and is a diagnostically challenging condition. Cutaneous manifestations typically occur in moderate to severe zinc deficiency and present ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2013.04.028
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Associations between gluten intake and psoriasis, psoriatic arthritis, and atopic dermatitis are poorly understood. OBJECTIVE:To determine whether increased gluten intake is associated with incident psoriasis, psoriatic arthritis, and atopic dermatitis. METHODS:Cohort studies among women in Nurses' Health ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2019.08.007
更新日期:2020-03-01 00:00:00
abstract::Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited available data suggest significant unmet care needs and low rates of palliati...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2020.08.029
更新日期:2020-08-12 00:00:00
abstract:BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2018.08.052
更新日期:2019-03-01 00:00:00