George Cheyne Shattuck's dissertation on the skin.

abstract：BACKGROUND:Evidence on long-term dupilumab treatment for atopic dermatitis in daily practice is lacking. OBJECTIVE:To investigate patient characteristics, treatment aspects, effectiveness, and safety of up to 84 weeks of dupilumab treatment. METHODS:An observational prospective cohort study was conducted of patients ...

journal_title：Journal of the American Academy of Dermatology

authors： Bosma AL,de Wijs LEM,Hof MH,van Nieuwenhuizen BR,Gerbens LAA,Middelkamp-Hup MA,Hijnen D,Spuls PI

更新日期：2020-11-01 00:00:00

abstract：:A number of dermatologic conditions may have associated esophageal manifestations. Teleologically, this may be because both the skin and the esophagus are lined by stratified squamous epithelium. Bullous dermatoses that may produce blisters, erosions, and/or stricture of the esophagus include cicatricial pemphigoid, H...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Touloukian J,Ahmed AR,Newcomer VD

更新日期：1981-06-01 00:00:00

abstract：:Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The precise cause of melasma remains unknown; however, there are many possible contributing factors. Because of its dermal component and tendency to relapse, melasma is...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Gover MD,Nouri K,Taylor S

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

journal_title：Journal of the American Academy of Dermatology

authors： Reinhold U,Seiter S,Ugurel S,Tilgen W

更新日期：1999-08-01 00:00:00

abstract：:This review begins with a classification of adverse drug reactions and a summary of those features that distinguish allergic from toxic and idiosyncratic reactions. Factors that influence the risk of developing drug allergy are then reviewed, followed by a discussion of the known and suspected immunologic mechanisms r...

journal_title：Journal of the American Academy of Dermatology

authors： VanArsdel PP Jr

更新日期：1982-05-01 00:00:00

abstract：:Vohwinkel's syndrome or keratoderma hereditaria mutilans is a diffuse, honeycombed, palmar, and plantar keratosis usually accompanied by pseudoainhum near the distal interphalangeal creases. The mutilating keratoderma associated with sensorineural hearing loss is thought to have an etiologic basis, resting on a mutati...

journal_title：Journal of the American Academy of Dermatology

authors： Solis RR,Diven DG,Trizna Z

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Physician visits provide invaluable opportunities to screen patients for skin cancer, yielding earlier detection and improved survival. OBJECTIVE:We sought to assess frequency of skin cancer screening by full body skin examinations (FBSE) by primary care physicians, patient attitudes toward FBSE, and risk f...

journal_title：Journal of the American Academy of Dermatology

authors： Rodriguez GL,Ma F,Federman DG,Rouhani P,Chimento S,Multach M,Kirsner RS

更新日期：2007-11-01 00:00:00

abstract：:We review experimental studies that address age-related changes in cutaneous barrier function and dermal blood vessel function. These differences have important implications in the understanding of age-related changes in the inflammatory process and topical drug delivery systems. ...

journal_title：Journal of the American Academy of Dermatology

authors： Harvell JD,Maibach HI

更新日期：1994-12-01 00:00:00

abstract：:Six months after the occurrence of pyoderma gangrenosum, subcorneal pustular dermatosis developed in a 60-year-old woman. The patient's serum was found to contain an IgA-lambda paraprotein. Although similar cases have been reported, this case is unique in that a distinct episode of pyoderma gangrenosum was followed by...

journal_title：Journal of the American Academy of Dermatology

authors： Kohl PK,Hartschuh W,Tilgen W,Frosch PJ

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:There is lack of studies on the diagnostic accuracy of dermatoscopy and reflectance confocal microscopy (RCM) for dark pigmented lesions. OBJECTIVE:To assess the diagnostic accuracy of dermatoscopy plus confocal microscopy for melanoma diagnosis of dark pigmented lesions in real life. METHODS:Prospective a...

journal_title：Journal of the American Academy of Dermatology

authors： Longo C,Mazzeo M,Raucci M,Cornacchia L,Lai M,Bianchi L,Peris K,Pampena R,Pellacani G

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:Condyloma acuminatum are common lesions caused by human papillomavirus (HPV). HPV is associated with many human cancers, and a vaccine now prevents infection with high-risk HPV. However, eradication of established disease is difficult, indicating that these lesions are capable of local immunosuppression. OB...

journal_title：Journal of the American Academy of Dermatology

authors： Le Poole C,Denman CJ,Arbiser JL

更新日期：2008-12-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：:We report a case of generalized cutaneous chronic graft-versus-host disease in a 17-month-old infant. Topical treatment with the novel ascomycin substance pimecrolimus once daily for 4 weeks led to a near complete clearance of skin lesions. Importantly, this excellent clinical response was obtained without additional ...

journal_title：Journal of the American Academy of Dermatology

authors： Ziemer M,Gruhn B,Thiele JJ,Elsner P

更新日期：2004-06-01 00:00:00

abstract：:Unilateral dermatomal superficial telangiectasia (UDST) may be congenital or acquired. Acquired UDST may occur coincident with physiologic states of estrogen increase, including puberty and pregnancy in women and adrenarche in men. Acquired UDST may also occur in estrogenized pathologic states such as chronic hepatic ...

journal_title：Journal of the American Academy of Dermatology

authors： Wilkin JK,Smith JG Jr,Cullison DA,Peters GE,Rodriquez-Rigau LJ,Feucht CL

更新日期：1983-04-01 00:00:00

abstract：:Erythropoietic protoporphyria is an inherited disorder characterized biochemically by a deficiency of ferrochelatase, the enzyme that catalyzes the incorporation of ferrous iron into protoporphyrin to form heme. We describe a patient who illustrates the unpredictability of the course of liver disease in erythropoietic...

journal_title：Journal of the American Academy of Dermatology

authors： Mercurio MG,Prince G,Weber FL Jr,Jacobs G,Zaim MT,Bickers DR

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Carney complex (CNC) is an autosomal dominant disorder associated with multiple neoplasms. OBJECTIVE:We report a case of a 40-year-old Caucasian man with a sporadic form of CNC. METHODS:This is a clinicopathologic description and molecular biological study with an emphasis on histopathologic findings. RES...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Sima R,Michal M,Hes O,Roucka P,Zarybnicka M,Hora M,Chudacek Z,Kazakov DV

更新日期：2009-07-01 00:00:00

abstract：:Renewed interest in experimental photocarcinogenesis was stimulated by the observation that skin cancers induced in mice by ultraviolet radiation are highly antigenic. Most of these cancers are rejected by the immune system on transplantation into a normal, genetically identical animal. This finding raised the questio...

journal_title：Journal of the American Academy of Dermatology

authors： Kripke ML

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid is an autoimmune disease that typically presents with tense bullae and severe pruritus. However, bullae can be lacking, a subtype termed nonbullous pemphigoid. OBJECTIVE:To summarize the reported characteristics of nonbullous pemphigoid. METHODS:The EMBASE and MEDLINE databases were sear...

journal_title：Journal of the American Academy of Dermatology

authors： Lamberts A,Meijer JM,Jonkman MF

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. OBJECTIVE:We sought to systematically review the literature relating to cutaneous ALHE to estimate its epidemiology and treatment out...

journal_title：Journal of the American Academy of Dermatology

authors： Adler BL,Krausz AE,Minuti A,Silverberg JI,Lev-Tov H

更新日期：2016-03-01 00:00:00

abstract：:We describe four patients who developed basal cell carcinoma (BCC) among multiple facial trichoepitheliomas. The only clinical feature that distinguished the carcinomas from the trichoepitheliomas was their larger size in three of the four patients. None of the lesions ulcerated. Whether the BCCs developed independent...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson SC,Bennett RG

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Although several studies have documented an undersupply of dermatologic services in the United States, little is known about the dermatopathology workforce. OBJECTIVE:Objectives included the following: (1) describe the dermatopathology workforce in the United States; (2) identify characteristics associated ...

journal_title：Journal of the American Academy of Dermatology

authors： Suwattee P,Cham PM,Abdollahi M,Warshaw EM

更新日期：2011-12-01 00:00:00

abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan C,Amor KT,Menter A

更新日期：2010-12-01 00:00:00

abstract：:Chronic skin ulcers, which are frequently located on the lower legs, are a common cause of patient morbidity and incur significant direct and indirect costs in their treatment. The most important process for their development is probably impairment of blood flow to the capillaries and small vessels. Examples of such u...

journal_title：Journal of the American Academy of Dermatology

authors： Krull EA

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Vitamin D3 analogs have been found to be effective in treating psoriasis. OBJECTIVE:We attempted to identify the targets and actions of vitamin D3 in the skin and to explore the availability of synthetic vitamin D3 analogs with selective actions on particular cell types or cell functions. METHODS:A review ...

journal_title：Journal of the American Academy of Dermatology

authors： Kragballe K

更新日期：1997-09-01 00:00:00

abstract：:The Americans With Disabilities Act (ADA) defines disability as a physical or mental impairment that substantially limits one or more major life activities. Although dermatology has received relatively little attention in the context of disability law, dermatologic diseases are properly covered by the ADA and are subj...

journal_title：Journal of the American Academy of Dermatology

authors： Curry ML,Curry JA,Cockerell CJ

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) has traditionally focused on minimizing recurrence and complication rates. However, the assessment of patient satisfaction and quality of life (QOL) is also important. These outcomes are best assessed by patient-reported outcome (PRO) ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee EH,Klassen AF,Nehal KS,Cano SJ,Waters J,Pusic AL

更新日期：2013-08-01 00:00:00

abstract：:Epidermolysis bullosa acquisita is a chronic, severe, subepidermal, blistering disease of the skin, characterized by marked resistance to topical and systemic therapy. This report concerns a well-documented case of a woman who had had epidermolysis bullosa acquisita for 6 years and had remained hospitalized continuous...

journal_title：Journal of the American Academy of Dermatology

authors： Crow LL,Finkle JP,Gammon WR,Woodley DT

更新日期：1988-11-01 00:00:00

abstract：:We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril. The cutaneous reaction remitted after withdrawal of captopril therapy. Unique to this case, however, was the substitution of another angiotensin-converting enzyme inhibitor, enalapril, without exacerbation of th...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Potter TS,Fox JN

更新日期：1992-02-01 00:00:00

abstract：:The case of a 2-year-old Puerto Rican boy is presented. Clinical and histologic features are detailed because he showed peculiar jet black patches of pigmentation on the fingers of the right hand. This case, except for the lack of progression of the disease after a 2-year period of follow-up, shows many similarities t...

journal_title：Journal of the American Academy of Dermatology

authors： González JR,Vázquez Botet M

更新日期：1980-02-01 00:00:00

abstract：:Blistering of light-exposed skin, pink-stained fluorescing diapers, and fluorescing peripheral erythrocytes led to diagnosis of congenital porphyria in an infant born to consanguineous parents. Although massive coproporphyrinuria and coproporphyrinemia initially suggested a coproporphyrinogen oxidase deficiency disord...

journal_title：Journal of the American Academy of Dermatology

authors： Huang JL,Zaider E,Roth P,Garcia O,Pollack S,Poh-Fitzpatrick MB

更新日期：1996-05-01 00:00:00