Vohwinkel's syndrome in three generations.

abstract：:Graft-versus-host disease (GVHD) is a T cell-mediated disease seen most commonly after hematopoietic stem cell transplantation. Rarely, a GVHD-like disease can be seen in patients with malignant thymoma. We describe a 50-year-old man with malignant thymoma who developed skin, liver, and intestinal manifestations simil...

journal_title：Journal of the American Academy of Dermatology

authors： Wadhera A,Maverakis E,Mitsiades N,Lara PN,Fung MA,Lynch PJ

更新日期：2007-10-01 00:00:00

abstract：:Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA

更新日期：1991-08-01 00:00:00

abstract：:Comparison of the TRUE Test patch test system with the chamber system recommended by the North American Contact Dermatitis Group showed concordance of results in 98% of tests with nickel, epoxy resin, and ethylenediamine dihydrochloride. Also, a panel of 12 TRUE Test screening allergens tested on 128 patients showed n...

journal_title：Journal of the American Academy of Dermatology

authors：

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Poor compliance with treatment advice in chronic conditions, such as psoriasis, represents a major challenge to health care professionals. Previous research suggests that the rate of noncompliance in chronic conditions may be as high as 40%. OBJECTIVE:This study was designed to examine self-reported complia...

journal_title：Journal of the American Academy of Dermatology

authors： Richards HL,Fortune DG,O'Sullivan TM,Main CJ,Griffiths CE

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Although dermatoscopy is widely used in Europe and Australia, little is known about dermatoscopy use by US dermatologists. OBJECTIVE:We sought to estimate the prevalence of dermatoscopy use by US dermatologists and examine associations with practice characteristics. METHODS:We conducted a cross-sectional s...

journal_title：Journal of the American Academy of Dermatology

authors： Engasser HC,Warshaw EM

更新日期：2010-09-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：:We studied the effects of two retinoids, naturally occurring all-trans-retinoic acid (retinoic acid) and the synthetic 4-hydroxyphenylretinamide (4-OH-PRT) on monolayer cultures of rabbit synovial fibroblasts and on explants of rabbit articular cartilage. Treatment of fibroblasts with phorbol myristate acetate (PMA; 1...

journal_title：Journal of the American Academy of Dermatology

authors： Brinckerhoff CE,Nagase H,Nagel JE,Harris ED Jr

更新日期：1982-04-01 00:00:00

abstract：:Urticaria is one of the more common skin conditions seen by physicians. Physical agents are an important cause of urticaria, with pressure or shearing forces being the most common. Dermographism is due to a combination of pressure and shearing forces and is present in a large number of healthy individuals. The purpose...

journal_title：Journal of the American Academy of Dermatology

authors： Wong RC,Fairley JA,Ellis CN

更新日期：1984-10-01 00:00:00

abstract：:Pharmacologic blockade of TNFalpha has been a highly effective approach to treating several immunologically mediated diseases, including rheumatoid arthritis, Crohn's disease, and psoriatic arthritis. 1,2,3 Both etanercept, the recombinant extracellular domain of the tumor necrosis factor receptor 2 (TNFR2), and infli...

journal_title：Journal of the American Academy of Dermatology

authors： Adams AE,Zwicker J,Curiel C,Kadin ME,Falchuk KR,Drews R,Kupper TS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The plasma concentration of bleomycin after injection of bleomycin into warts is unknown, as is the long-term stability of bleomycin solution. OBJECTIVE:Our purpose was to measure plasma bleomycin concentration after injection of bleomycin into warts, to relate histologic and immunocytochemical changes in w...

journal_title：Journal of the American Academy of Dermatology

authors： James MP,Collier PM,Aherne W,Hardcastle A,Lovegrove S

更新日期：1993-06-01 00:00:00

abstract：:Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...

journal_title：Journal of the American Academy of Dermatology

authors： Sajben FP,Gibbs NF,Friedlander SF

更新日期：1999-08-01 00:00:00

abstract：:Lipoid proteinosis (Urbach-Wiethe disease) is a rare, recessively inherited disorder that is characterized by the deposition of hyaline-like material in the skin, oral cavity, and other tissues. It usually appears in infancy with hoarseness. We report a case of lipoid proteinosis in a 10-year-old boy that demonstrates...

journal_title：Journal of the American Academy of Dermatology

authors： Konstantinov K,Kabakchiev P,Karchev T,Kobayasi T,Ullman S

更新日期：1992-08-01 00:00:00

abstract：:The safety and efficacy of 0.1% tacrolimus ointment for the treatment of psoriasis on the face, intertriginous areas, or both were evaluated in an open-label, clinical trial of 21 patients with psoriasis. Patients applied 0.1% tacrolimus ointment twice daily for 8 weeks. Efficacy was assessed through the investigator'...

journal_title：Journal of the American Academy of Dermatology

authors： Freeman AK,Linowski GJ,Brady C,Lind L,Vanveldhuisen P,Singer G,Lebwohl M

更新日期：2003-04-01 00:00:00

abstract：:A fatal case of transfusion-associated graft-versus-host disease developed in a premature infant after receiving several blood products, including nonirradiated white blood cells. Transfusion-associated graft-versus-host disease can be prevented. Irradiation of blood products is the least controversial and most effect...

journal_title：Journal of the American Academy of Dermatology

authors： Berger RS,Dixon SL

更新日期：1989-05-01 00:00:00

abstract：:A persistent periocular dermatitis resulting from the prolonged use of topical fluorinated corticosteroids that resembled the perioral variety was observed in three patients. All topical therapy was ineffective until systemic tetracycline was administered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher AA

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Amelanotic acral melanoma (AAM) is very rare and difficult to diagnose both clinically and pathologically. Complete-type AAM shows no black to brown pigmentation in the lesion, whereas incomplete-type AAM shows focal or subtle pigmentation. AAM has been the subject of few investigations. OBJECTIVES:We analy...

journal_title：Journal of the American Academy of Dermatology

authors： Choi YD,Chun SM,Jin SA,Lee JB,Yun SJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Accurate evaluation of basal cell carcinoma (BCC) in the United States was not possible before the 2011 release of BCC-specific International Classification of Diseases, Ninth Revision, Clinical Modification codes. OBJECTIVE:We sought to describe BCC (including locally advanced BCC [LABCC]) incidence/preval...

journal_title：Journal of the American Academy of Dermatology

authors： Goldenberg G,Karagiannis T,Palmer JB,Lotya J,O'Neill C,Kisa R,Herrera V,Siegel DM

更新日期：2016-11-01 00:00:00

abstract：:The association of palmoplantar hyperkeratosis and mycosis fungoides (MF) has been described less frequently in the dermatologic literature. We present a patient with MF who developed hyperkeratosis of the palms and soles. Histologic examination of a specimen from the left palm showed microscopic changes of MF. ...

journal_title：Journal of the American Academy of Dermatology

authors： Aram H,Zeidenbaum M

更新日期：1985-11-01 00:00:00

abstract：:An intensely pruritic dermatosis that occurred in a woman during the third trimester of pregnancy is described. The clinical manifestations included red follicular papules symmetrically distributed on the skin of the forearms, abdomen, thighs, and legs. The histopathologic findings were not specific. However, immunopa...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,Ingber A,Hazaz B,David M,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The negative pigment network (NPN) is seen as a negative of the pigmented network and it is purported to be a melanoma-specific structure. OBJECTIVES:We sought to assess the frequency, sensitivity, specificity, and odds ratios (ORs) of NPN between melanoma cases and a group of control lesions. METHODS:Digi...

journal_title：Journal of the American Academy of Dermatology

authors： Pizzichetta MA,Talamini R,Marghoob AA,Soyer HP,Argenziano G,Bono R,Corradin MT,De Giorgi V,Gonzalez MA,Kolm I,Kopf AW,Malvehy J,Nami N,Oliviero M,Pellacani G,Puig S,Rabinovitz H,Rubegni P,Seidenari S,Stanganelli I,

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

journal_title：Journal of the American Academy of Dermatology

authors： Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Access to dermatologists is low among Medicaid-insured patients. Higher clinic nonattendance among Medicaid-insured patients might affect provider decisions to accept these patients. OBJECTIVE:To determine the effect of different scheduling policies on the attendance among children seen at a pediatric derma...

journal_title：Journal of the American Academy of Dermatology

authors： Chaudhry SB,Siegfried E,Sheikh UA,Simonetta C,Butala N,Armbrecht E

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Early recognition of melanoma is the key in preventing metastatic disease. OBJECTIVE:The aim of this study was to evaluate diagnostic ability of general practitioners (GPs) and dermatologists concerning pigmented skin lesions in general and melanoma in particular. We also investigated whether the diagnostic...

journal_title：Journal of the American Academy of Dermatology

authors： Brochez L,Verhaeghe E,Bleyen L,Naeyaert JM

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. STUDY PATIENTS:The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. RESULTS:Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Boztepe G,Akinci H,Sahin S,Karaduman A,Evans SE,Erkin G,Atakan N,Akan T,Kölemen F

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Lazova R,Tantcheva-Poor I,Sigal AC

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Guselkumab, an interleukin-23 blocker, was superior to adalimumab in treating moderate to severe psoriasis in a phase II trial. OBJECTIVES:We sought to compare efficacy and safety of guselkumab with adalimumab and placebo in patients with psoriasis treated for 1 year. METHODS:Patients were randomized to gu...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Papp KA,Griffiths CE,Randazzo B,Wasfi Y,Shen YK,Li S,Kimball AB

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE:This study was conducted to evaluate the efficacy and safety of BTX-A treatment of glabellar lines. METHODS:Patients with moderate to severe glabellar lines at maximum frown received intramuscular inje...

journal_title：Journal of the American Academy of Dermatology

authors： Carruthers JA,Lowe NJ,Menter MA,Gibson J,Nordquist M,Mordaunt J,Walker P,Eadie N,BOTOX Glabellar Lines I Study Group.

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Pulsed dye laser treatment and other cosmetic procedures result in significant bruising. Claims have been made regarding the efficacy of topical vitamin K in both preventing and speeding the clearing of bruising; however, well-controlled studies are lacking. OBJECTIVE:The purpose of this study is to evaluat...

journal_title：Journal of the American Academy of Dermatology

authors： Shah NS,Lazarus MC,Bugdodel R,Hsia SL,He J,Duncan R,Baumann L

更新日期：2002-08-01 00:00:00

abstract：:The responses to aggressive gluten challenge of two dermatitis herpetiformis patients with normal gut mucosa and negative serum findings for IgA endomysial antibodies while on normal diets indicate that these patients have a latent gluten-sensitive enteropathy. This was shown further by the control of skin lesions in ...

journal_title：Journal of the American Academy of Dermatology

authors： Chorzelski TP,Rosinska D,Beutner EH,Sulej J,Kumar V

更新日期：1988-04-01 00:00:00

abstract：:A case of Flegel's disease, or hyperkeratosis lenticularis perstans, is reported. This rare chronic disorder is characterized by asymptomatic hyperkeratotic papules, usually located on the lower extremities. Most reported cases have been from Europe. We report a case of hyperkeratosis lenticularis perstans from our in...

journal_title：Journal of the American Academy of Dermatology

authors： Pearson LH,Smith JG Jr,Chalker DK

更新日期：1987-01-01 00:00:00