Abstract:
:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate can deposit in extrarenal sites such as the heart, walls of arteries and veins, bone, and skin. We report a patient who presented with acute renal failure and later experienced livedo reticularis and peripheral gangrene before the diagnosis of primary hyperoxaluria was established. A skin biopsy specimen demonstrated numerous characteristic elongate to diamond-shaped, radially oriented, pale yellow translucent oxalate crystals within the vessels, and vessel walls of the subcutaneous fat that were strongly birefringent under polarized light.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HCdoi
10.1067/mjd.2002.105475subject
Has Abstractpub_date
2002-02-01 00:00:00pages
S16-8issue
2 Suppl Case Reportseissn
0190-9622issn
1097-6787pii
S0190-9622(02)70223-5journal_volume
46pub_type
杂志文章abstract:BACKGROUND:An estimated 750,000 melanoma survivors in the United States are at increased risk of subsequent primary cancers. OBJECTIVE:We sought to assess the risk of developing subsequent primary cancers among people with cutaneous melanoma. METHODS:Using 1992 to 2006 data from the National Cancer Institute Surveill...
journal_title:Journal of the American Academy of Dermatology
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更新日期:2011-11-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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pub_type: 临床试验,杂志文章
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journal_title:Journal of the American Academy of Dermatology
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abstract::Pain is a central component of illness and suffering, yet unfortunately it is frequently undertreated. In dermatology, many acute and chronic conditions are characterized by pain that may require therapeutic intervention in addition to medical treatment aimed at treating the primary disease. To date, however, there ar...
journal_title:Journal of the American Academy of Dermatology
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更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Access to dermatologists is low among Medicaid-insured patients. Higher clinic nonattendance among Medicaid-insured patients might affect provider decisions to accept these patients. OBJECTIVE:To determine the effect of different scheduling policies on the attendance among children seen at a pediatric derma...
journal_title:Journal of the American Academy of Dermatology
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abstract:BACKGROUND:Cholinergic urticaria is primarily seen in young adults, but little is known about its prevalence. OBJECTIVE:A prospective study was designed to investigate the frequency and severity of cholinergic urticaria in this age group. METHODS:Four hundred ninety-three high school and university students (15 to 35...
journal_title:Journal of the American Academy of Dermatology
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更新日期:1994-12-01 00:00:00