Pruritus and nonspecific nodules preceding myelomonocytic leukemia.

abstract：:With the growth of dermatologic surgery the appropriate use of local anesthesia is becoming an important issue. Thoughtful use of local anesthesia can improve the patient's experience and facilitate the surgical procedure. In this review we discuss historical and pharmacologic aspects of local anesthetic agents. Empha...

journal_title：Journal of the American Academy of Dermatology

authors： Grekin RC,Auletta MJ

更新日期：1988-10-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：UNLABELLED:Mycophenolate mofetil (MMF) is the prodrug of mycophenolic acid (MPA), a medication used to treat psoriasis in the 1970s until side effects and the concern of carcinogenesis led to its discontinuation. The prodrug, MMF, emerged decades later in the transplant field. Dermatologists have since used MMF off-lab...

journal_title：Journal of the American Academy of Dermatology

authors： Orvis AK,Wesson SK,Breza TS Jr,Church AA,Mitchell CL,Watkins SW

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Dermatopathologists often are asked by clinicians to report margins on punch excisions of melanocytic lesions. OBJECTIVE:We sought to determine the adequacy of surgical margins on melanocytic lesions submitted with intention of complete excision using punch removal technique. METHODS:We conducted prospecti...

journal_title：Journal of the American Academy of Dermatology

authors： Chang TT,Somach SC,Wagamon K,Somani AK,Pomeranz J,Jaworsky C,Bass J,Winfield HL,Sigel JE,Rosenberg AS

更新日期：2009-06-01 00:00:00

abstract：:A distinctive new hair condition, the loose anagen syndrome, features anagen hairs that are loosely anchored and easily pulled from the scalp. The children studied had sparse hair that did not grow long and that pulled easily from the scalp. The majority of patients were blond girls, aged 2 to 5 years, but both sexes ...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Gummer CL

更新日期：1989-02-01 00:00:00

abstract：:The most problematic vulvovaginal conditions are familiar to dermatologists but may exhibit distinct clinical features or medication management because of the anatomic location. The second article in this continuing medical education series focuses on management pearls for treating vulvar diseases. We highlight key co...

journal_title：Journal of the American Academy of Dermatology

authors： Mauskar MM,Marathe K,Venkatesan A,Schlosser BJ,Edwards L

更新日期：2020-06-01 00:00:00

abstract：:This study compares the histopathologic characteristics of photodistributed and nonphotodistributed lichenoid drug eruptions in 13 patients. Both types have been said to be, in an unknown proportion, different from idiopathic lichen planus in that they can involve the deep as well as the superficial plexus, can contai...

journal_title：Journal of the American Academy of Dermatology

authors： West AJ,Berger TG,LeBoit PE

更新日期：1990-10-01 00:00:00

abstract：:A new disorder of the hair follicle is described that leads to increased fragility of the shaft. Light microscopic studies of hair follicles revealed disturbances of keratinization in the shafts that are very likely responsible for the breakage. The most consistent change seen by transmission electron microscopy was i...

journal_title：Journal of the American Academy of Dermatology

authors： Birnbaum PS,Baden HP,Bronstein BR,Nakagawa H,Hori Y

更新日期：1986-07-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Warren R. Heymann, MD, are provided after each discussion as a topic summary and are provided here as a special service t...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Lazova R,Tantcheva-Poor I,Sigal AC

更新日期：2010-11-01 00:00:00

abstract：:Malignant melanoma is considered the most lethal skin cancer if it is not detected and treated during its early stages. About 10% of melanoma patients report a family history of melanoma; however, individuals with features of true hereditary melanoma (ie, unilateral lineage, multigenerational, multiple primary lesions...

journal_title：Journal of the American Academy of Dermatology

authors： Soura E,Eliades PJ,Shannon K,Stratigos AJ,Tsao H

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The effects of systemic therapy on mortality risk among patients with psoriasis are not fully understood. OBJECTIVE:To evaluate the impact of systemic treatment on mortality risk in patients enrolled in the Psoriasis Longitudinal Assessment and Registry. METHODS:Nested case-control analyses were performed ...

journal_title：Journal of the American Academy of Dermatology

authors： Langley RG,Poulin Y,Srivastava B,Lafferty KP,Fakharzadeh S,Langholff W,Augustin M

更新日期：2021-01-01 00:00:00

abstract：:We report the case of a congenitally deaf white male with mild palmoplantar keratoderma, ichthyosiform scaling, follicular hyperkeratosis, and mild keratitis, features consistent with keratitis-ichthyosis-deafness syndrome. His major problem was severe, disfiguring, inflammatory dissecting folliculitis of the scalp, h...

journal_title：Journal of the American Academy of Dermatology

authors： Montgomery JR,White TW,Martin BL,Turner ML,Holland SM

更新日期：2004-09-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Reports of necrobiotic granulomas or granuloma annulare in patients with malignant lymphoma are rare. OBJECTIVE:Our intent was to determine any unique clinical or histopathologic features in patients with granuloma annulare and lymphoma. METHODS:We reviewed the medical records and biopsy material from 13 p...

journal_title：Journal of the American Academy of Dermatology

authors： Barksdale SK,Perniciaro C,Halling KC,Strickler JG

更新日期：1994-07-01 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) is a poorly understood neurovascular disorder characterized by pain, altered sensation, motor disturbance, soft tissue changes, vasomotor changes, and autonomic changes that occurs after trauma to an extremity. Unilateral leukonychia, Beau's lines, nailfold swelling, and nail clubbin...

journal_title：Journal of the American Academy of Dermatology

authors： Pucevich B,Spencer L,English JC 3rd

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. OBJECTIVE:To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. METHODS:...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA,Whiting DA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Glial cell line-derived neurotrophic factor (GDNF) and a related family member, neurturin (NTN), and their cognate receptors (GFRalpha-1 and GFRalpha-2, for GDNF and NTN, respectively) are distal members of the transforming growth factor-beta superfamily. They are involved in the control of murine hair folli...

journal_title：Journal of the American Academy of Dermatology

authors： Adly MA,Assaf HA,Pertile P,Hussein MR,Paus R

更新日期：2008-02-01 00:00:00

abstract：:We report a case of epidermodysplasia verruciformis (EV)-like lesions in a patient with graft-versus-host disease after peripheral blood stem cell transplantation from his HLA-matched brother. The patient presented with a diffuse papular eruption that was clinically consistent with graft-versus-host disease; however, ...

journal_title：Journal of the American Academy of Dermatology

authors： Kunishige JH,Hymes SR,Madkan V,Wyatt AJ,Uptmore D,Lazar AJ,Giralt S,Rady P,Tyring S

更新日期：2007-11-01 00:00:00

abstract：:Pain is a central component of illness and suffering, yet unfortunately it is frequently undertreated. In dermatology, many acute and chronic conditions are characterized by pain that may require therapeutic intervention in addition to medical treatment aimed at treating the primary disease. To date, however, there ar...

journal_title：Journal of the American Academy of Dermatology

authors： Enamandram M,Rathmell JP,Kimball AB

更新日期：2015-10-01 00:00:00

abstract：:Onychomadesis is defined as spontaneous separation of the nail plate from the nail bed, beginning at its proximal end and resulting in the shedding of the nail. It has been associated with a variety of clinical settings, including systemic illnesses, generalized skin diseases, and drug therapies. There have been a sma...

journal_title：Journal of the American Academy of Dermatology

authors： Mehra A,Murphy RJ,Wilson BB

更新日期：2000-08-01 00:00:00

abstract：:Small erythematous or cyanotic lesions on the hands and feet of four patients with antiphospholipid antibodies are described. These discrete lesions outline capillaries and do not disappear when pressure is applied. The histologic features are identical to those described in skin thrombotic syndrome associated with an...

journal_title：Journal of the American Academy of Dermatology

authors： Grob JJ,San Marco M,Aillaud MF,Andrac L,Gabriel B,Juhan-Vague I,Mercier C,Bonerandi JJ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Genital or vulval lichen planus (VLP) may have a disabling effect on a patient's quality of life. Evidence-based management guidelines are lacking for VLP. OBJECTIVE:We sought to review clinical presentation and treatment of patients who received a diagnosis of VLP. METHODS:The 100 consecutive patients who...

journal_title：Journal of the American Academy of Dermatology

authors： Fahy CMR,Torgerson RR,Davis MDP

更新日期：2017-12-01 00:00:00

abstract：:Pressure ulcers are localized areas of tissue necrosis that result from unrelieved pressure. They are graded or staged according to the degree of tissue damage observed. The main etiologic factors include pressure, shearing forces, friction, and moisture. The clinical course may be complicated by several conditions in...

journal_title：Journal of the American Academy of Dermatology

authors： Kanj LF,Wilking SV,Phillips TJ

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature. OBJECTIVE:To provide up-to-date information regarding the state of teledermatology programs in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Wu J,Kovarik CL,Goldyne ME,Oh DH,McKoy KC,Shippy AM,Pak HS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Dermoscopy improves the recognition of melanoma and Spitz nevus but occasionally melanoma may exhibit a symmetric pattern mimicking Spitz nevus. OBJECTIVE:We sought to investigate the likelihood of finding melanoma when excising a symmetric Spitzoid-looking lesion in patients aged 12 years or older. METHOD...

journal_title：Journal of the American Academy of Dermatology

authors： Lallas A,Moscarella E,Longo C,Kyrgidis A,de Mestier Y,Vale G,Guida S,Pellacani G,Argenziano G

更新日期：2015-01-01 00:00:00

abstract：:To evaluate the possible association of other malignancies with basal cell carcinoma, we reviewed 1973 consecutive patients with basal cell carcinoma. We searched the Swedish Cancer Registry for records reporting malignancies in the study population (1958-1984) and the expected number of malignancies was calculated on...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Wallberg P,Eklund G

更新日期：1991-08-01 00:00:00

abstract：:We describe the clinical and biochemical features of an infant with marked transient porphyrinemia in whom blistering developed while the infant was undergoing phototherapy for severe Rh isoimmunization. The cause of the transient porphyrinemia was likely to be multifactorial--abnormal porphyrin metabolism or accumula...

journal_title：Journal of the American Academy of Dermatology

authors： Mallon E,Wojnarowska F,Hope P,Elder G

更新日期：1995-08-01 00:00:00