当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY期刊下所有文献 > Likelihood of finding melanoma when removing a Spitzoid-looking lesion in patients aged 12 years or older.

Likelihood of finding melanoma when removing a Spitzoid-looking lesion in patients aged 12 years or older.

Abstract：

BACKGROUND:Dermoscopy improves the recognition of melanoma and Spitz nevus but occasionally melanoma may exhibit a symmetric pattern mimicking Spitz nevus. OBJECTIVE:We sought to investigate the likelihood of finding melanoma when excising a symmetric Spitzoid-looking lesion in patients aged 12 years or older. METHODS:This study included patients aged 12 years or older with symmetric, Spitzoid-looking lesions that were diagnosed histopathologically as Spitz nevus or melanoma. Demographic, clinical, and dermoscopic variables were included in the analysis. We used χ(2) for nonparametric comparisons. Crude odds ratios and 95% confidence intervals were calculated by univariate logistic regression. RESULTS:Of 384 included lesions, 333 (86.7%) were histopathologically diagnosed as Spitz nevus and 51 (13.3%) as melanoma. The risk of melanoma significantly increased with increasing age, being 50% or higher after the age of 50 years. LIMITATIONS:Limitations are retrospective design, exclusion of patients younger than 12 years, lack of detailed histopathologic data, and limited sample size. CONCLUSION:Our results confirm the observation that melanoma may be dermoscopically indistinguishable from Spitz nevi, strongly suggesting that the only safe strategy not to miss melanoma is to excise all Spitzoid-looking lesions in patients aged 12 years or older.

journal_name

J Am Acad Dermatol

journal_title

Journal of the American Academy of Dermatology

authors

Lallas A,Moscarella E,Longo C,Kyrgidis A,de Mestier Y,Vale G,Guida S,Pellacani G,Argenziano G

doi

10.1016/j.jaad.2014.09.037

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

47-53

issue

1

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(14)02000-3

journal_volume

72

pub_type

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