Granuloma annulare localized to the palms.

abstract：:Topical nitrogen mustard is an alkylating agent. Its efficacy in treating alopecia areata was reported in an uncontrolled study. We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 pa...

journal_title：Journal of the American Academy of Dermatology

authors： Bernardo O,Tang L,Lui H,Shapiro J

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Guselkumab, an interleukin-23 blocker, was superior to adalimumab in treating moderate to severe psoriasis in a phase II trial. OBJECTIVES:We sought to compare efficacy and safety of guselkumab with adalimumab and placebo in patients with psoriasis treated for 1 year. METHODS:Patients were randomized to gu...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Papp KA,Griffiths CE,Randazzo B,Wasfi Y,Shen YK,Li S,Kimball AB

更新日期：2017-03-01 00:00:00

abstract：:Punctate hyperkeratosis of the palms and soles is an uncommon autosomal dominant condition. We report a 65-year-old man with this condition and review the literature. With electron microscopy, we have examined both clinically affected and adjacent clinically unaffected palmar skin. The only ultrastructural differences...

journal_title：Journal of the American Academy of Dermatology

authors： Rubenstein DJ,Schwartz RA,Hansen RC,Payne CM

更新日期：1980-07-01 00:00:00

abstract：:We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case th...

journal_title：Journal of the American Academy of Dermatology

authors： Umbert IJ,Su WP

更新日期：1989-12-01 00:00:00

abstract：:Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl amino...

journal_title：Journal of the American Academy of Dermatology

authors： Braathen LR,Szeimies RM,Basset-Seguin N,Bissonnette R,Foley P,Pariser D,Roelandts R,Wennberg AM,Morton CA,International Society for Photodynamic Therapy in Dermatology.

更新日期：2007-01-01 00:00:00

abstract：:A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lantos G,Fisher BK,Contreras M

更新日期：1988-12-01 00:00:00

abstract：:Infantile leukemia accounts for only 3% of childhood leukemia. Leukemia cutis occurs in 25% to 30% of infants with congenital leukemia and is more frequently associated with acute myeloid leukemia than with acute lymphoblastic leukemia. We describe an infant in whom hyperpigmented macules that developed when the patie...

journal_title：Journal of the American Academy of Dermatology

authors： Yen A,Sanchez R,Oblender M,Raimer S

更新日期：1996-02-01 00:00:00

abstract：:Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin disease driven by keratinocyte hyperproliferation. During the next 20 years, the role of the immune system and T-helper (Th) cells in psori...

journal_title：Journal of the American Academy of Dermatology

authors： Lynde CW,Poulin Y,Vender R,Bourcier M,Khalil S

更新日期：2014-07-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：:We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils...

journal_title：Journal of the American Academy of Dermatology

authors： Kuan YZ,Chiou HT,Chang HC,Chan HL,Kuo TT

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Given the increasing demographic diversity in the United States, clarifying relationships between race, color, ethnicity, and disease processes is critical. OBJECTIVES:We sought to examine the correlation between objective measures of skin pigmentation, racial identification, and physician-diagnosed and sel...

journal_title：Journal of the American Academy of Dermatology

authors： Chan JL,Ehrlich A,Lawrence RC,Moshell AN,Turner ML,Kimball AB

更新日期：2005-04-01 00:00:00

abstract：:Reflections from instruments in the surgical field involving the CO2 laser beam present a serious ocular hazard. In addition to the use of plastic or glass protective eyewear, this hazard can be minimized by utilizing anodized instruments and recognizing the specific distances at which various reflections are no longe...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman NR,Saleeby ER,Rubin MG,Sandu T,Krull EA

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Although rare in the general population, highly penetrant germline mutations in CDKN2A are responsible for 5%-40% of melanoma cases reported in melanoma-prone families. We sought to determine whether MELPREDICT was generalizable to a global series of families with melanoma and whether performance improvement...

journal_title：Journal of the American Academy of Dermatology

authors： Taylor NJ,Mitra N,Qian L,Avril MF,Bishop DT,Bressac-de Paillerets B,Bruno W,Calista D,Cuellar F,Cust AE,Demenais F,Elder DE,Gerdes AM,Ghiorzo P,Goldstein AM,Grazziotin TC,Gruis NA,Hansson J,Harland M,Hayward NK,Ho

更新日期：2019-08-01 00:00:00

abstract：:Angioedema is characterized by localized swelling of sudden onset affecting the skin and/or mucous membranes. It can be classified into hereditary and acquired forms. Hereditary angioedema is a rare disease inherited as an autosomal dominant trait and caused by a deficiency of C1-esterase inhibitor. Acute attacks are ...

journal_title：Journal of the American Academy of Dermatology

authors： Greaves M,Lawlor F

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Long-term adverse effects of propranolol treatment for infantile hemangioma (IH) in young children have been suggested. OBJECTIVE:To compare growth and development in children treated with propranolol for IH with nontreated healthy controls. METHODS:Eighty two (73%) children with IH aged 43 to 51 months tr...

journal_title：Journal of the American Academy of Dermatology

authors： Moyakine AV,Kerstjens JM,Spillekom-van Koulil S,van der Vleuten CJ

更新日期：2016-07-01 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：:We report the case of a congenitally deaf white male with mild palmoplantar keratoderma, ichthyosiform scaling, follicular hyperkeratosis, and mild keratitis, features consistent with keratitis-ichthyosis-deafness syndrome. His major problem was severe, disfiguring, inflammatory dissecting folliculitis of the scalp, h...

journal_title：Journal of the American Academy of Dermatology

authors： Montgomery JR,White TW,Martin BL,Turner ML,Holland SM

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Melanoma patients with negative nodes after sentinel lymph node biopsy are a heterogeneous group. Current guidelines fail to adequately stratify surveillance and treatment for this group. Also, there is scarce data on adjuvant treatments for these patients. OBJECTIVE:To create a nomogram including clinical ...

journal_title：Journal of the American Academy of Dermatology

authors： Bertolli E,de Macedo MP,Calsavara VF,Pinto CAL,Duprat Neto JP

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Although hypersensitivity reactions are well characterized for certain medications, vancomycin-associated drug-induced hypersensitivity syndrome (DIHS), or drug reaction with eosinophilia and systemic symptoms (DRESS), has yet to be defined. OBJECTIVE:To better define the clinical phenotype of vancomycin-as...

journal_title：Journal of the American Academy of Dermatology

authors： Madigan LM,Fox LP

更新日期：2019-07-01 00:00:00

abstract：UNLABELLED:Cutaneous vascular malformations are rare disorders representing errors in vascular development. These lesions occur much less commonly but are often confused with the common infantile hemangioma. It is important to properly diagnose vascular malformations because of their distinct differences in morbidity, ...

journal_title：Journal of the American Academy of Dermatology

authors： Garzon MC,Huang JT,Enjolras O,Frieden IJ

更新日期：2007-04-01 00:00:00

abstract：:Two patients with the benign type of follicular mucinosis (FM) are presented. Their clinical features and course were characteristic for this subgroup of FM. Light and electron microscopy, direct immunofluorescence, and immunoperoxidase cell marker studies were undertaken to characterize the nature of the disease proc...

journal_title：Journal of the American Academy of Dermatology

authors： Lancer HA,Bronstein BR,Nakagawa H,Bhan AK,Mihm MC Jr

更新日期：1984-05-01 00:00:00

abstract：:Parachlorometaxylenol is used as a germicide in many topical products. To our knowledge, this is the first case of dermatitis from parachlorometaxylenol in electrocardiograph electrodes used with cardiac monitors. The patient also had hand eczema from a germicidal soap containing parachlorometaxylenol. In addition, ou...

journal_title：Journal of the American Academy of Dermatology

authors： Ranchoff RE,Steck WD,Taylor JS,Evey P

更新日期：1986-08-01 00:00:00

abstract：:We report a case of atypical Reiter's syndrome occurring in a female patient who had severe, ulcerative vulvar disease develop in association with conjunctivitis, low back pain, stomatitis, and psoriasiform skin lesions. Vulvar lesions have rarely been described in Reiter's syndrome and are not well characterized. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lotery HE,Galask RP,Stone MS,Sontheimer RD

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:The focal facial dermal dysplasias (FFDD) are a genetically heterogeneous group of disorders characterized by congenital bilateral scarlike facial lesions, with or without associated facial anomalies. The cases have been reported under various names; thus the nosology is confusing and unclear. OBJECTIVE:Our...

journal_title：Journal of the American Academy of Dermatology

authors： Kowalski DC,Fenske NA

更新日期：1992-10-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor usually involving soft tissue and, in rare cases, the skin. Histologically and biologically it is considered to be a borderline neoplasm between an angiolymphoid hyperplasia with eosinophilia and an epithelioid angiosarcoma. Here we describe an 1...

journal_title：Journal of the American Academy of Dermatology

authors： Forschner A,Harms D,Metzler G,Sönnichsen K,Ulmer A,Rassner G,Fierlbeck G

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The risk of acquiring Lyme disease has been evaluated by xenodiagnostic procedures with laboratory strains of Borrelia burgdorferi and laboratory-reared Ixodes ticks, or by clinical trials in which diagnosis was based on clinical findings, culture, or serologic tests. OBJECTIVE:Our purpose was to determine ...

journal_title：Journal of the American Academy of Dermatology

authors： Berger BW,Johnson RC,Kodner C,Coleman L

更新日期：1995-02-01 00:00:00

abstract：:We hereby report a case presenting a rare form of secondary syphilis with an unusual nodular eruption accompanied by pruritus and generalized lymphadenopathy, bearing a striking resemblance to lymphoma. The histologic picture was also misleading and was compatible with lymphocytoma cutis. The diagnosis was eventually ...

journal_title：Journal of the American Academy of Dermatology

authors： Hodak E,David M,Rothem A,Bialowance M,Sandbank M

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus (CLE). Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Shipman WD,Vernice NA,Demetres M,Jorizzo JL

更新日期：2020-03-01 00:00:00

abstract：:Sjögren syndrome (SS) is an autoimmune connective tissue disorder (CTD) that principally affects the lacrimal and salivary glands. Although SS is 1 of the 3 most common autoimmune CTDs alongside systemic lupus erythematosus and progressive systemic sclerosis, it is the least researched CTD overall. SS poses a particul...

journal_title：Journal of the American Academy of Dermatology

authors： Jhorar P,Torre K,Lu J

更新日期：2018-10-01 00:00:00

abstract：:Primary cutaneous CD30 (Ki-1)-positive, large cell lymphomas (LCLs) represent a recently recognized group of cutaneous T-cell lymphomas with a favorable prognosis. The characteristic features of this cutaneous lymphoma are reviewed, differences with primary noncutaneous CD30+ LCLs emphasized, and its relation with oth...

journal_title：Journal of the American Academy of Dermatology

authors： Willemze R,Beljaards RC

更新日期：1993-06-01 00:00:00