Electrocardiography electrode and hand dermatitis from parachlorometaxylenol.

abstract：BACKGROUND:Several changing clinical and histopathologic melanoma trends occurred from the 1950s to the 1980s. OBJECTIVE:The purpose of this study was to evaluate melanoma trends during the past decade and to compare present trends to those documented during the past four decades. METHODS:Sex, age at diagnosis, locat...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson TM,Dolan OM,Hamilton TA,Lu MC,Swanson NA,Lowe L

更新日期：1998-05-01 00:00:00

abstract：:There has been a resurgence of syphilis in the past decade. Uncommonly, diffuse hair loss, termed essential alopecia, is the only sign of syphilitic infection. We describe two patients with syphilis in whom the first sign of disease was alopecia and discuss the clinical and histopathologic findings of essential syphil...

journal_title：Journal of the American Academy of Dermatology

authors： Cuozzo DW,Benson PM,Sperling LC,Skelton HG 3rd

更新日期：1995-05-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Evidence on long-term dupilumab treatment for atopic dermatitis in daily practice is lacking. OBJECTIVE:To investigate patient characteristics, treatment aspects, effectiveness, and safety of up to 84 weeks of dupilumab treatment. METHODS:An observational prospective cohort study was conducted of patients ...

journal_title：Journal of the American Academy of Dermatology

authors： Bosma AL,de Wijs LEM,Hof MH,van Nieuwenhuizen BR,Gerbens LAA,Middelkamp-Hup MA,Hijnen D,Spuls PI

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Butenafine hydrochloride, a benzylamine derivative with potent antifungal activity, has been used in Japan to treat superficial fungal diseases. OBJECTIVE:We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomiz...

journal_title：Journal of the American Academy of Dermatology

authors： Savin R,De Villez RL,Elewski B,Hong S,Jones T,Lowe N,Lucky A,Reyes B,Stewart D,Willis I

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Although etanercept is used as a continuous therapy for moderate to severe plaque psoriasis, intermittent use may be necessary in some instances. OBJECTIVE:In this randomized, open-label study, we evaluated the effectiveness and safety of continuous versus interrupted etanercept therapy. METHODS:All patien...

journal_title：Journal of the American Academy of Dermatology

authors： Moore A,Gordon KB,Kang S,Gottlieb A,Freundlich B,Xia HA,Stevens SR

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:While progress has been made in defining the clinical and histopathologic features of high-risk cutaneous squamous cell carcinoma (HRcSCC), optimal staging guidelines remain elusive. OBJECTIVE:We seek to guide clinical practice regarding nodal staging options for patients with HRcSCC via review of evolving ...

journal_title：Journal of the American Academy of Dermatology

authors： Fox M,Brown M,Golda N,Goldberg D,Miller C,Pugliano-Mauro M,Schmults C,Shin T,Stasko T,Xu YG,Nehal K,High Risk Squamous Cell Carcinoma Workgroup.,Dermatologic Surgery Section of the Association of Professors of Dermatology.

更新日期：2019-08-01 00:00:00

abstract：:With the introduction of the Medicare Access and Children's Health Insurance Program Reauthorization Act, clinicians who are not eligible for an exemption must choose to participate in 1 of 2 new reimbursement models: the Merit-based Incentive Payment System or Alternative Payment Models (APMs). Although most dermatol...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,Miller JJ,Nguyen HP,Forman HP,Bolognia JL,VanBeek MJ,Group for Research of Policy Dynamics in Dermatology.

更新日期：2017-06-01 00:00:00

abstract：:The occurrence of Langerhans cell histiocytosis (LCH) and malignancy in the same patient is rare. When LCH occurs concomitantly with acute leukemia, distinct temporal patterns often exist; acute myelogenous leukemia (AML) typically succeeds LCH, whereas acute lymphocytic leukemia (ALL) usually precedes it. We report a...

journal_title：Journal of the American Academy of Dermatology

authors： Chiles LR,Christian MM,McCoy DK,Hawkins HK,Yen AH,Raimer SS

更新日期：2001-12-01 00:00:00

abstract：:Chemotherapy-induced alopecia is a distressing side effect common to certain treatment regimens in oncology. Unfortunately, chemotherapy-induced alopecia is an often overlooked or minor factor among our current research priorities and thus advances in amelioration have been minimal. This review offers a comprehensive ...

journal_title：Journal of the American Academy of Dermatology

authors： Chon SY,Champion RW,Geddes ER,Rashid RM

更新日期：2012-07-01 00:00:00

abstract：:We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case th...

journal_title：Journal of the American Academy of Dermatology

authors： Umbert IJ,Su WP

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid is an autoimmune blistering skin disease that predominantly affects the elderly. Conventional therapy using high-dose systemic corticosteroids and immunosuppressive agents can be ineffective in some patients and produce adverse events and relapses. Hence, alternate therapies are required. ...

journal_title：Journal of the American Academy of Dermatology

authors： Ahmed AR,Shetty S,Kaveri S,Spigelman ZS

更新日期：2016-04-01 00:00:00

abstract：:A 4-year-old girl with failure to thrive and intense pruritus associated with Alagille syndrome is described. The clinical features of this autosomal dominant disorder are reviewed. This case highlights the importance of recognizing the severe pruritus as a manifestation of the disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz R,Rehder K,Parsons DJ,Morrell DS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Lipedematous alopecia and lipedematous scalp are two similar unusual conditions mostly affecting healthy black women. OBJECTIVE:The purpose of our study was to report three cases of this condition with emphasis on clinical and histologic findings, and to review the literature on the subject. METHODS:The st...

journal_title：Journal of the American Academy of Dermatology

authors： Martín JM,Monteagudo C,Montesinos E,Guijarro J,Llombart B,Jordá E

更新日期：2005-01-01 00:00:00

abstract：:Psychosomatic dermatology is practiced in some manner by every dermatologist. In spite of this, there has been a virtual void in the literature from the middle 1950s until the present time. The relationship to physiologic phenomena, as well as a classification of psychosomatic dermatology, is reviewed. Dermatologic pa...

journal_title：Journal of the American Academy of Dermatology

authors： Medansky RS,Handler RM

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Appropriate primary end points in randomized controlled trials (RCTs) improve the quality of the measurement and enable comparison of the findings with those of other trials. OBJECTIVE:To assess the quality of reporting primary end points in RCTs recently published in dermatology journals. METHODS:We ident...

journal_title：Journal of the American Academy of Dermatology

authors： Kim DY,Oh S,Yoon HS

更新日期：2020-04-22 00:00:00

abstract：:Patients with basal cell carcinoma and solar keratoses were treated with etretinate. Substantial and prolonged clinical improvement was seen. All patients with solar keratoses showed a decrease in the mean area and number of lesions and eight patients demonstrated complete healing clinically. Two patients experienced ...

journal_title：Journal of the American Academy of Dermatology

authors： Hughes BR,Marks R,Pearse AD,Gaskell SA

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:There are multiple therapeutic options for the treatment of moderate to severe psoriasis. The process of choosing among potential treatment options requires both the physician and the patient to weigh the benefits of individual modalities against their potential risks. Traditional systemic therapies for psor...

journal_title：Journal of the American Academy of Dermatology

authors： Patel RV,Clark LN,Lebwohl M,Weinberg JM

更新日期：2009-06-01 00:00:00

abstract：:Aquagenic urticaria is a rare disorder characterized by the occurrence of pruritus and wheals after temporary contact with water. The familial occurrence of aquagenic urticaria over 3 generations is reported here in association with familial lactose intolerance, a condition in which the enzyme lactase encoded on chrom...

journal_title：Journal of the American Academy of Dermatology

authors： Treudler R,Tebbe B,Steinhoff M,Orfanos CE

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:While scalp alopecia represents a distinctive feature of chronic graft-versus-host disease (cGVHD), little is known about the clinical and histologic presentation of hair loss. OBJECTIVES:We sought to classify the clinical presentations and histologic findings of chronic hair loss in patients with cutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Marks DH,Naftulin JS,Penzi LR,Manatis-Lornell A,Yasuda MR,Chapman CM,Rao SR,Saavedra A,Senna MM

更新日期：2019-11-01 00:00:00

abstract：:A diabetic renal transplant recipient developed fever, generalized rash, and genital ulcers which showed typical histologic changes of cytomegalovirus (CMV) infection in the dermal vascular endothelium. This infection was confirmed by rising serologic titer of specific antibody, positive viral cultures, and typical nu...

journal_title：Journal of the American Academy of Dermatology

authors： Pariser RJ

更新日期：1983-12-01 00:00:00

abstract：:Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:The genetic heterogeneity of melanomas and melanocytic nevi of the female genital tract is poorly understood. OBJECTIVE:We aim to characterize the frequency of mutations of the following genes: BRAF, NRAS, KIT, GNA11, and GNAQ in female genital tract melanomas. We also characterize the frequency of BRAF mut...

journal_title：Journal of the American Academy of Dermatology

authors： Tseng D,Kim J,Warrick A,Nelson D,Pukay M,Beadling C,Heinrich M,Selim MA,Corless CL,Nelson K

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：:Forty cases of lentigo maligna (LM) and lentigo maligna melanoma (LMM) treated by conventional fractionated radiotherapy are reviewed. Fourteen of seventeen LM patients are alive and well 4 months to 5 years following irradiation, one patient died of intercurrent disease without recurrence, and two had residual or rec...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood AR

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:The plasma concentration of bleomycin after injection of bleomycin into warts is unknown, as is the long-term stability of bleomycin solution. OBJECTIVE:Our purpose was to measure plasma bleomycin concentration after injection of bleomycin into warts, to relate histologic and immunocytochemical changes in w...

journal_title：Journal of the American Academy of Dermatology

authors： James MP,Collier PM,Aherne W,Hardcastle A,Lovegrove S

更新日期：1993-06-01 00:00:00

abstract：:Polymorphous sweat gland carcinoma is an unusual, recently described variant of low-grade malignant adnexal neoplasm of the skin characterized by a prolonged clinical course and predilection for the extremities. We describe a case of recurrent polymorphous sweat gland carcinoma in a 56-year-old man who presented with ...

journal_title：Journal of the American Academy of Dermatology

authors： Ronnen M,Ben-Dor D,Huszar M

更新日期：2002-06-01 00:00:00

abstract：:Punctate hyperkeratosis of the palms and soles is an uncommon autosomal dominant condition. We report a 65-year-old man with this condition and review the literature. With electron microscopy, we have examined both clinically affected and adjacent clinically unaffected palmar skin. The only ultrastructural differences...

journal_title：Journal of the American Academy of Dermatology

authors： Rubenstein DJ,Schwartz RA,Hansen RC,Payne CM

更新日期：1980-07-01 00:00:00

abstract：:We present a case of cutaneous infection due to Cladophialophora bantiana, an agent of phaeohyphomycosis. The patient developed a nodule with pustule formation on the dorsum of the left hand; no trauma was reported. The lesion was successfully treated with itraconazole and surgical excision. Histopathologically, there...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Warren NG,Kelly LW

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Needle puncture and infiltrational anesthesia is generally required for minor cutaneous surgical procedures and may be associated with anxiety, fear, discomfort, and pain. The use of topical anesthetics such as eutectic lidocaine/prilocaine 5% cream may provide an alternative means of delivering anesthesia. ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG

更新日期：1996-09-01 00:00:00