Intense pruritus and failure to thrive in Alagille syndrome.

abstract：BACKGROUND:Actinic keratosis (AK) is the earliest clinical manifestation of squamous cell carcinoma. Metastatic SCC causes the majority of the 1300 to 2300 deaths attributed to nonmelanoma skin cancer in the United States each year. Recent studies have shown that intralesional administration of interferon can be used s...

journal_title：Journal of the American Academy of Dermatology

authors： Persaud AN,Shamuelova E,Sherer D,Lou W,Singer G,Cervera C,Lamba S,Lebwohl MG

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Silverberg AI,Malka E,Silverberg NB

更新日期：2010-06-01 00:00:00

abstract：:As discussed in the first article in this continuing medical education series, angioinvasive fungal infections pose a significant risk to immunocompromised and immunocompetent patients alike, with a potential for severe morbidity and high mortality. The first article in this series focused on the epidemiology and clin...

journal_title：Journal of the American Academy of Dermatology

authors： Berger AP,Ford BA,Brown-Joel Z,Shields BE,Rosenbach M,Wanat KA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Acne is a multifactorial disease in which androgens appear to play an important role. A low-dose oral contraceptive containing 20 microg of ethinyl estradiol and 100 microg of levonorgestrel (EE/LNG) has been shown to improve biochemical markers of androgenicity. Lowering bioavailable androgens may improve a...

journal_title：Journal of the American Academy of Dermatology

authors： Leyden J,Shalita A,Hordinsky M,Swinyer L,Stanczyk FZ,Weber ME

更新日期：2002-09-01 00:00:00

abstract：:Malacoplakia, an inflammatory disease characterized by accumulations of phagocytic macrophages, occurs primarily in immunocompromised individuals. Cutaneous involvement is rare. Two men, each with a renal allograft, had expanding nodules on the temple and perianal area (case 1) and perianal, inguinal, and scrotal skin...

journal_title：Journal of the American Academy of Dermatology

authors： Lowitt MH,Kariniemi AL,Niemi KM,Kao GF

更新日期：1996-02-01 00:00:00

abstract：:Patients with HIV and AIDS are living longer because of advancements in antiretroviral therapy. These patients are often susceptible to debilitating inflammatory disorders that are refractory to standard treatment. We discuss the relationship of tumor necrosis factor-alpha and HIV and then review 27 published cases of...

journal_title：Journal of the American Academy of Dermatology

authors： Gallitano SM,McDermott L,Brar K,Lowenstein E

更新日期：2016-05-01 00:00:00

abstract：:A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

journal_title：Journal of the American Academy of Dermatology

authors： Jaworsky C,Ratz JL,Dijkstra JW

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:While scalp alopecia represents a distinctive feature of chronic graft-versus-host disease (cGVHD), little is known about the clinical and histologic presentation of hair loss. OBJECTIVES:We sought to classify the clinical presentations and histologic findings of chronic hair loss in patients with cutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Marks DH,Naftulin JS,Penzi LR,Manatis-Lornell A,Yasuda MR,Chapman CM,Rao SR,Saavedra A,Senna MM

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Telemedicine technology holds great promise for dermatologic health care delivery. However, the clinical outcomes of digital image consultations (teledermatology) must be compared with traditional clinic-based consultations. OBJECTIVE:Our purpose was to assess and compare the reliability and accuracy of der...

journal_title：Journal of the American Academy of Dermatology

authors： Whited JD,Hall RP,Simel DL,Foy ME,Stechuchak KM,Drugge RJ,Grichnik JM,Myers SA,Horner RD

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Genetic and environmental risk factors have been associated with the development of multiple primary melanomas (MPM). We hypothesized that individuals with MPM may have increased predisposition to developing internal malignancies. OBJECTIVE:To identify the risk of subsequent malignancies in MPM patients. M...

journal_title：Journal of the American Academy of Dermatology

authors： Cai ED,Swetter SM,Sarin KY

更新日期：2018-10-01 00:00:00

abstract：:Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria and angioedema. The administration of thyroid hormone may alleviate chronic urticaria and/or angioedema in selected patients. This review focuses on the association of thyroid autoimmunity with chronic urticaria and/or angioede...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Oral methoxsalen (psoralen) and ultraviolet A radiation (PUVA) is a highly effective therapy for psoriasis and many other skin conditions. It is carcinogenic. Previously we reported an increased risk of melanoma that first emerged 15 years after first treatment. OBJECTIVE:Our purpose is to present additiona...

journal_title：Journal of the American Academy of Dermatology

authors： Stern RS,PUVA Follow up Study.

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:The color, architecture, symmetry, and homogeneity (CASH) algorithm for dermoscopy includes a feature not used in prior algorithms, namely, architecture. Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms. OBJECTIVE:We sought ...

journal_title：Journal of the American Academy of Dermatology

authors： Henning JS,Dusza SW,Wang SQ,Marghoob AA,Rabinovitz HS,Polsky D,Kopf AW

更新日期：2007-01-01 00:00:00

abstract：:Two patients with atypical histologic and immunohistochemical findings in nevi after cryotherapy are reported. Patient 1, a 32-year-old white woman, presented to our cancer center with two changing moles that had been treated with liquid nitrogen therapy by her primary care provider. After cryotherapy, these two lesio...

journal_title：Journal of the American Academy of Dermatology

authors： Adeniran AJ,Prieto VG,Chon S,Duvic M,Diwan AH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile. However, little is known about the safety of spironolactone in breast cancer (BC) survivors. Because spironolactone has estrogenic effects, there is a theoretical risk...

journal_title：Journal of the American Academy of Dermatology

authors： Wei C,Bovonratwet P,Gu A,Moawad G,Silverberg JI,Friedman AJ

更新日期：2020-10-01 00:00:00

abstract：:Betel is a compound of natural substances chewed for its psychostimulating effects. Betel is composed of the nut of the areca palm (Areca catechu), the leaf of the betel pepper (Piper betle), and lime (calcium hydroxide). Approximately 200 million persons chew betel regularly throughout the western Pacific basin and s...

journal_title：Journal of the American Academy of Dermatology

authors： Norton SA

更新日期：1998-01-01 00:00:00

abstract：:A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

journal_title：Journal of the American Academy of Dermatology

authors： De Villez RL

更新日期：1987-03-01 00:00:00

abstract：:A 52-year-old man with a history of melanoma presented to the emergency department with a massive intracranial hemorrhage. The patient deteriorated rapidly and was being considered as a potential organ donor. Three years before presentation, the patient had undergone wide excision of a 3.75-mm melanoma from his back w...

journal_title：Journal of the American Academy of Dermatology

authors： Cotter MA,Tristani-Firouzi P

更新日期：2006-06-01 00:00:00

abstract：:A group of 420 neonates underwent total cutaneous and oral mucosal examinations during the first week of life. Skin lesions were seen in almost every baby (99.3%). The eight most common dermatoses were desquamation (65.0%), Epstein's pearls (56.0%), sebaceous hyperplasia (48.0%), milia (36%), toxic erythema (34.8%), s...

journal_title：Journal of the American Academy of Dermatology

authors： Rivers JK,Frederiksen PC,Dibdin C

更新日期：1990-07-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely dermatologic topics. Commentaries from the Dialogues Editor-in-Chief, Warren R. Heymann, MD, are provided after each discussion as a topic summary. These highlights are prov...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Genetic and environmental components may contribute to acne causation. OBJECTIVE:We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne. METHODS:We conducted a case-control study in dermatologic outpatient clin...

journal_title：Journal of the American Academy of Dermatology

authors： Di Landro A,Cazzaniga S,Parazzini F,Ingordo V,Cusano F,Atzori L,Cutrì FT,Musumeci ML,Zinetti C,Pezzarossa E,Bettoli V,Caproni M,Lo Scocco G,Bonci A,Bencini P,Naldi L,GISED Acne Study Group.

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Glial cell line-derived neurotrophic factor (GDNF) and a related family member, neurturin (NTN), and their cognate receptors (GFRalpha-1 and GFRalpha-2, for GDNF and NTN, respectively) are distal members of the transforming growth factor-beta superfamily. They are involved in the control of murine hair folli...

journal_title：Journal of the American Academy of Dermatology

authors： Adly MA,Assaf HA,Pertile P,Hussein MR,Paus R

更新日期：2008-02-01 00:00:00

abstract：:The presence of the discoid lupus erythematosus (DLE) skin lesion in a patient with systemic lupus erythematosus (SLE) has been suggested to be a marker of less frequent and less severe renal disease. The clinical and laboratory features of seventeen patients who were seen in a dermatology practice and who had DLE as ...

journal_title：Journal of the American Academy of Dermatology

authors： Callen JP

更新日期：1985-02-01 00:00:00

abstract：:Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl amino...

journal_title：Journal of the American Academy of Dermatology

authors： Braathen LR,Szeimies RM,Basset-Seguin N,Bissonnette R,Foley P,Pariser D,Roelandts R,Wennberg AM,Morton CA,International Society for Photodynamic Therapy in Dermatology.

更新日期：2007-01-01 00:00:00

abstract：:Critical to the proper management of pyoderma gangrenosum are correct diagnosis, identification and treatment of any underlying disorder, and the proper choice of topical and systemic therapy. Many agents are available for the treatment of pyoderma gangrenosum. We review the current therapeutic options, their efficacy...

journal_title：Journal of the American Academy of Dermatology

authors： Chow RK,Ho VC

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...

journal_title：Journal of the American Academy of Dermatology

authors： Boyd AS,Stasko TS,Tang YW

更新日期：2011-01-01 00:00:00

abstract：:Pruritus is a common and often times difficult to treat symptom in many dermatologic and systemic diseases. For pruritus with an inflammatory or autoimmune origin, therapies such as topical corticosteroids and antihistamines are often initiated. However, in the case that these and additional systemic therapies are ine...

journal_title：Journal of the American Academy of Dermatology

authors： Sharma D,Kwatra SG

更新日期：2016-02-01 00:00:00

abstract：:The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

journal_title：Journal of the American Academy of Dermatology

authors： Katz SI

更新日期：1985-09-01 00:00:00

abstract：:Good to excellent clinical results have been obtained in the treatment of severe inflammatory acne (acne conglobata, acne fulminans, and acne conglobata with hidradenitis and dissecting cellulitis of the scalp) with orally administered isotretinoin (13-cis-retinoic acid). Similar promising results have been obtained i...

journal_title：Journal of the American Academy of Dermatology

authors： Plewig G,Nikolowski J,Wolff HH

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2...

journal_title：Journal of the American Academy of Dermatology

authors： Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJ

更新日期：2008-10-01 00:00:00