Intense pruritus and failure to thrive in Alagille syndrome.

abstract：BACKGROUND:Dermatomyositis (DM) is a multisystem autoimmune disease, in which serologic evidence of immune responses to disease-specific antigenic targets is found in approximately 50% to 70% of patients. Recently, melanoma differentiation-associated gene 5 (MDA5) has been identified as a DM-specific autoantigen that a...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino D,Chung L,Zwerner J,Rosen A,Casciola-Rosen L

更新日期：2011-07-01 00:00:00

abstract：:We report a cluster of primary cutaneous aspergillosis in six children with hematologic malignancy. When first seen, they had hemorrhagic bullae caused by Aspergillus flavus, Aspergillus fumigatus, and Aspergillus niger at the sites of insertion of intravenous cannulas or where arm boards had been taped to the extremi...

journal_title：Journal of the American Academy of Dermatology

authors： Grossman ME,Fithian EC,Behrens C,Bissinger J,Fracaro M,Neu HC

更新日期：1985-02-01 00:00:00

abstract：:The deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a pigmented lesion that commonly arises on the head and neck in the first few decades of life. Histopathologically, the DPN is wedge-shaped and contains melanocytes that exhibit deep infiltration into the dermis. Given these features,...

journal_title：Journal of the American Academy of Dermatology

authors： Strazzula L,Senna MM,Yasuda M,Belazarian L

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Genetic and environmental components may contribute to acne causation. OBJECTIVE:We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne. METHODS:We conducted a case-control study in dermatologic outpatient clin...

journal_title：Journal of the American Academy of Dermatology

authors： Di Landro A,Cazzaniga S,Parazzini F,Ingordo V,Cusano F,Atzori L,Cutrì FT,Musumeci ML,Zinetti C,Pezzarossa E,Bettoli V,Caproni M,Lo Scocco G,Bonci A,Bencini P,Naldi L,GISED Acne Study Group.

更新日期：2012-12-01 00:00:00

abstract：:Bowenoid papulosis is an uncommon genital dysplasia induced by human papillomavirus infection. Clinically, it usually resembles persistent warts, but histologically it may be suggestive of squamous cell carcinoma in situ. This unusual disorder and recent advances in our understanding of it are reviewed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz RA,Janniger CK

更新日期：1991-02-01 00:00:00

abstract：:Thrombocytopenia was observed in 3 patients with cutaneous angiosarcoma of the scalp and face. A sudden decrease in the platelet count occurred in association with rapid enlargement of primary or metastatic lesions. Neither antiplatelet antibody nor platelet-associated IgG was detected. Increased serum levels of beta-...

journal_title：Journal of the American Academy of Dermatology

authors： Satoh T,Takahashi Y,Yokozeki H,Katayama I,Nishioka K

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Voriconazole, an antifungal agent, is associated with various cutaneous reactions, including phototoxicity, accelerated photoaging, and skin cancer. Incidence and risk factors for these reactions in children have not been well described. OBJECTIVE:We sought to determine the incidence of and factors associat...

journal_title：Journal of the American Academy of Dermatology

authors： Sheu J,Hawryluk EB,Guo D,London WB,Huang JT

更新日期：2015-02-01 00:00:00

abstract：:Keloidal scars are abnormal scars of uncertain etiology with a predilection for certain racial groups. Although many articles have been published on the management of these scars, there are no definitive treatment protocols. Our objective was to examine the scientific quality of the literature on therapy for keloidal ...

journal_title：Journal of the American Academy of Dermatology

authors： Shaffer JJ,Taylor SC,Cook-Bolden F

更新日期：2002-02-01 00:00:00

abstract：:Xeroderma pigmentosum is associated with severe actinic degeneration of the skin. Our patient with xeroderma pigmentosum showed increasing actinic damage in some areas covered by clothes. We therefore performed a complete evaluation of the patient's exposure to ultraviolet radiation. This included transmission measure...

journal_title：Journal of the American Academy of Dermatology

authors： Bech-Thomsen N,Wulf HC,Ullman S

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic features of childhood melanoma are poorly characterized. Atypical clinical presentations and ambiguous microscopic findings may contribute to diagnostic delays. OBJECTIVES:We sought to determine whether conventional ABCDE melanoma detection criteria (Asymmetry, Border irregulari...

journal_title：Journal of the American Academy of Dermatology

authors： Cordoro KM,Gupta D,Frieden IJ,McCalmont T,Kashani-Sabet M

更新日期：2013-06-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:Since proteolytic processes are prominent in psoriasis, sera of forty-five psoriatics were examined for alpha 1-antitrypsin (alpha 1-AT) phenotype and eighteen sera, for alpha 1-AT content and function. Five sera (11.1%) had heterozygous phenotypes (2 MZ and 3 MS), a prevalence of Z and S variants similar to that repo...

journal_title：Journal of the American Academy of Dermatology

authors： Lipkin G,Galdston M,Kueppers F

更新日期：1984-10-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：:A new section entitled "Dermatology Grand Rounds at the NIH" appears this month. The idea behind it is to provide a unique look at instructive dermatologic cases being presented at the weekly Dermatology Branch Grand Rounds at the National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland. Pati...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Cobb MW,Turner ML

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for pa...

journal_title：Journal of the American Academy of Dermatology

authors： Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJ

更新日期：2008-09-01 00:00:00

abstract：:Galli-Galli disease is an inherited disease characterized by slowly progressive and disfiguring reticulate hyperpigmentation of the flexures, clinically and histopathologically diagnostic for Dowling-Degos disease, but also associated with suprabasal, nondyskeratotic acantholysis. A few patients exhibiting these featu...

journal_title：Journal of the American Academy of Dermatology

authors： Braun-Falco M,Volgger W,Borelli S,Ring J,Disch R

更新日期：2001-11-01 00:00:00

abstract：:Fibrous harmartoma of infancy is a benign soft tissue tumor that occurs in the first few years of life. Although the lesion is not distinctive clinically, it has a characteristic microscopic appearance. Only 12 cases of fibrous hamartoma of infancy have been reported in the dermatology literature. ...

journal_title：Journal of the American Academy of Dermatology

authors： Scott DM,Peña JR,Omura EF

更新日期：1999-11-01 00:00:00

abstract：:A patient with acquired immunodeficiency syndrome presented with multiple pruritic papules and nodules over the trunk and extremities. Biopsy specimens from two of these lesions contained granules within abscesses of the papillary dermis. There were numerous gram-positive cocci within the granules. Culture of one lesi...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Kitces EN,Neafie RC

更新日期：1987-01-01 00:00:00

abstract：:With the growth of dermatologic surgery the appropriate use of local anesthesia is becoming an important issue. Thoughtful use of local anesthesia can improve the patient's experience and facilitate the surgical procedure. In this review we discuss historical and pharmacologic aspects of local anesthetic agents. Empha...

journal_title：Journal of the American Academy of Dermatology

authors： Grekin RC,Auletta MJ

更新日期：1988-10-01 00:00:00

abstract：:As summarized in the first article in this continuing medical education series, the currently available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic disease. Emerging data also suggest associations between psoriasis and other comorbidities beyond psoriatic arthritis, including chr...

journal_title：Journal of the American Academy of Dermatology

authors： Takeshita J,Grewal S,Langan SM,Mehta NN,Ogdie A,Van Voorhees AS,Gelfand JM

更新日期：2017-03-01 00:00:00

abstract：:There is significant confusion in the literature when describing vascular anomalies, and vascular malformations are often misnamed or incorrectly classified. Part I of this two-part series on the diagnosis and management of extensive vascular malformations of the lower limbs will discuss the dermatologist's role in th...

journal_title：Journal of the American Academy of Dermatology

authors： Redondo P,Aguado L,Martínez-Cuesta A

更新日期：2011-11-01 00:00:00

abstract：:Sixteen patients with granular cell tumors were seen between 1964 and 1979. The medical data of these patients showed an average age incidence of 39 years and a greater frequency among Negroes (69%) and in female patients (62.5%). The most common sign (in 12 of 16 patients) was the presence of an asymptomatic mass. Th...

journal_title：Journal of the American Academy of Dermatology

authors： Apisarnthanarax P

更新日期：1981-08-01 00:00:00

abstract：:In this third and last part of our review of cutaneous vascular proliferations we include malignant vascular neoplasms and a group of heterogeneous cutaneous neoplasms characterized by a significant vascular component. We also review some disorders that, in our opinion, have been erroneously considered as vascular neo...

journal_title：Journal of the American Academy of Dermatology

authors： Requena L,Sangueza OP

更新日期：1998-02-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Psoralen plus ultraviolet A (PUVA) for the treatment of psoriasis has never been evaluated using the Psoriasis Area Severity Index (PASI) in a randomized, double-blind, placebo-controlled trial. The lack of such data limits our capacity to estimate PUVA's efficacy relative to other treatment options that are...

journal_title：Journal of the American Academy of Dermatology

authors： Sivanesan SP,Gattu S,Hong J,Chavez-Frazier A,Bandow GD,Malick F,Kricorian G,Koo J

更新日期：2009-11-01 00:00:00

abstract：:We describe a 6-year-old boy with a granulomatous lesion on the upper aspect of his left arm. Fusarium solani infection was confirmed by biopsy studies and cultures. The biopsy specimen showed an unusually extensive dermal invasion with fungal hyphae. This is an uncommon clinical presentation for deep cutaneous infect...

journal_title：Journal of the American Academy of Dermatology

authors： Nakamura Y,Xu X,Saito Y,Tateishi T,Takahashi T,Kawachi Y,Otsuka F

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Patients with onychomycosis may experience physical impairment and psychological and social limitations related to their infection. OBJECTIVE:The object of this study was to compare health-related quality-of-life scores of patients with onychomycosis with those of a control group. METHODS:The interview ins...

journal_title：Journal of the American Academy of Dermatology

authors： Lubeck DP

更新日期：1998-05-01 00:00:00

abstract：:A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lantos G,Fisher BK,Contreras M

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00

abstract：:An examination of 380 patients was accomplished in order to determine the frequency of occurrence of pigmentary demarcation lines in an unselected population. Both white and black patients were included in the study, and there was an equal sex distribution. Separation of data by age groups enabled us to determine that...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Carter JM,Rodman OG

更新日期：1987-03-01 00:00:00