Abstract：
BACKGROUND:Lipedematous alopecia and lipedematous scalp are two similar unusual conditions mostly affecting healthy black women. OBJECTIVE:The purpose of our study was to report three cases of this condition with emphasis on clinical and histologic findings, and to review the literature on the subject. METHODS:The study includes clinical, echographic, and histologic findings of 3 patients, complemented with a literature review. RESULTS:Two cases of lipedematous alopecia and one of lipedematous scalp in 3 white women had echographic confirmation of an increased subcutaneous layer. The presence of ectatic lymphatic vessels in the two cases with hair loss was particularly emphasized. CONCLUSIONS:Our findings suggest a lessened role of racial factors, but confirms the sex implications in these related conditions, and stress the potential significance of lymphangiectatic vessels in the development of alopecia in these patients.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Martín JM,Monteagudo C,Montesinos E,Guijarro J,Llombart B,Jordá Edoi
10.1016/j.jaad.2004.05.016subject
Has Abstractpub_date
2005-01-01 00:00:00pages
152-6issue
1eissn
0190-9622issn
1097-6787pii
S0190962204013118journal_volume
52pub_type
杂志文章,评审abstract：:The Papillon-Lefèvre syndrome is characterized by palmoplantar hyperkeratosis and juvenile periodontitis that results in the precocious loss of both the deciduous and permanent teeth. We report a patient with Papillon-Lefèvre syndrome associated with acroosteolysis, an association that has not been previously describe...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(91)70127-n
更新日期：1991-05-01 00:00:00
abstract：:Oral retinoids are among the drugs of choice for pustular and erythrodermic psoriasis. In addition, retinoids are effective in combination with other topical and systemic agents for the treatment of plaque-type psoriasis. Acitretin, the active retinoid metabolite, has replaced etretinate in retinoid therapy of psorias...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(99)70359-2
更新日期：1999-09-01 00:00:00
abstract：:Kapos's varicelliform eruption usually occurs in persons with active skin disease of various types; however, in atopic dermatitis the condition may occur when the underlying disease is inactive. Two cases of widespread herpes simplex infection associated with Darier's disease are reported. In both cases, infection occ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(79)70024-7
更新日期：1979-10-01 00:00:00
abstract：:Sjögren syndrome (SS) is an autoimmune connective tissue disorder (CTD) that principally affects the lacrimal and salivary glands. Although SS is 1 of the 3 most common autoimmune CTDs alongside systemic lupus erythematosus and progressive systemic sclerosis, it is the least researched CTD overall. SS poses a particul...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2018.05.021
更新日期：2018-10-01 00:00:00
abstract：:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sha...
journal_title：Journal of the American Academy of Dermatology
pub_type： 共识发展会议,杂志文章
doi：10.1016/j.jaad.2011.06.032
更新日期：2012-03-01 00:00:00
abstract：:Psychosomatic dermatology is practiced in some manner by every dermatologist. In spite of this, there has been a virtual void in the literature from the middle 1950s until the present time. The relationship to physiologic phenomena, as well as a classification of psychosomatic dermatology, is reviewed. Dermatologic pa...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(81)70081-1
更新日期：1981-08-01 00:00:00
abstract：:A woman with pemphigus vulgaris was treated by plasma exchange. Four separate exchanges of approximately 4,000 ml each were performed over a 2-week period. The patient's pemphigus antibody titer decreased from 1/320 before the first exchange to 1/20 after the final exchange, and no new lesions developed for 3 weeks fo...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(81)70033-1
更新日期：1981-03-01 00:00:00
abstract：:Apoptosis, a genetically encoded program that results in cell death, represents a fundamental biologic concept that has relevance to a wide range of dermatologic processes. This review discusses the basic biology of apoptosis and its relevance to cutaneous disease. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(97)80266-6
更新日期：1997-06-01 00:00:00
abstract：:A case of phaeohyphomycosis caused by Phialophora richardsiae is presented. The patient was a 30-year-old man with end stage malignant lymphoma. A subcutaneous abscess that developed on the dorsum of the right foot was removed surgically but immediately recurred. The causative mold was isolated from the pus in the les...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(88)70200-5
更新日期：1988-09-01 00:00:00
abstract：:Our case series report is the first documented depiction of the appearance of aphthous ulcers secondary to imiquimod application. This case series presentation discusses the underlying pathophysiology of aphthous ulcer development and imiquimod therapy in terms of the stimulation of proinflammatory cytokines, such as ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2004.06.045
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. OBJECTIVE AND METHODS:The clinical features and treatment results of 18 children with FH are described. RESULTS:Local excision was the most common procedure. Surgery was radical ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jaad.2005.11.1076
更新日期：2006-05-01 00:00:00
abstract：:Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should i...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(81)70053-7
更新日期：1981-05-01 00:00:00
abstract：:We report a case of fatal pancreatitis heralded by the presence of cutaneous panniculitis without abdominal pain or other stigmata of the disease. Although cutaneous fat necrosis has been associated with pancreatitis, it is unusual as the presenting complaint of this relatively common disease. In vitro evidence sugges...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(87)70213-8
更新日期：1987-08-01 00:00:00
abstract：BACKGROUND:Although only large congenital melanocytic nevi (CMN) are associated with a significantly high risk for malignant transformation, CMN of all sizes are prone to changes in clinical appearance in early childhood and thus are often biopsied or excised. While CMNs typically exhibit benign behavior, atypical hist...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2016.12.026
更新日期：2017-05-01 00:00:00
abstract：:Patients with dark skin can present with morphologic variants, subtle disease presentations, and disease manifestations requiring unique management and therapies. With African Americans, Asians, and Hispanic Americans becoming a significant portion of the population, dermatologists must be able to diagnose and manage ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2005.10.068
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2009.11.024
更新日期：2010-06-01 00:00:00
abstract：:Warthin's tumor (papillary cystadenoma lymphomatosum) is a well-known benign tumor of the parotid gland. Extraparotid tumors occasionally arise in the cervical region, where they may well be seen by the dermatologist. The following is a case report of an extraparotid Warthin's tumor encountered in a dermatology practi...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(99)70499-8
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:Onychomycosis (fungal infection of the toenails or fingernails) is common, affecting up to 8% of the general population. Telephone and mailed surveys conducted to study this disease are usually completed via patient self-report. The validity of the counts of diseased nails reported by the patients participat...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2007.09.022
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND:Biologics targeting interleukin 17A (IL-17A) allow for rapid clearance of psoriatic plaques, with a clinically favorable safety profile. OBJECTIVES:To compare the safety and efficacy of ixekizumab, an IL-17A antagonist, with the safety and efficacy of the IL-12/23 inhibitor ustekinumab through 52 weeks of t...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jaad.2018.06.039
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Atopic dermatitis is a common multifactorial disease that seems to be increasing in frequency. OBJECTIVE:Our purpose was to determine the increased prevalence of atopic dermatitis in North Europe. METHODS:Approximately 3000 7-year-old children in Denmark, Germany, and Sweden were enrolled in a cross-sectio...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(96)90009-2
更新日期：1996-05-01 00:00:00
abstract：:Nodular primary localized cutaneous amyloidosis is an uncommon disorder for which there is no consistently satisfactory treatment. The amyloid fibrils are thought to have an immunoglobulin light chain derivation and systemic involvement must be excluded in all cases. We report a patient with a large scalp lesion of no...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(86)70132-1
更新日期：1986-06-01 00:00:00
abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2016.07.038
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Diet is a modulator of inflammation that might impact inflammatory skin diseases. OBJECTIVE:To assess the relationship between pro-inflammatory dietary patterns and incident psoriasis, psoriatic arthritis (PsA), and atopic dermatitis (AD). METHODS:We conducted cohort studies among women in the Nurses' Heal...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2019.02.038
更新日期：2019-06-01 00:00:00
abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2013.02.025
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2010.02.051
更新日期：2011-01-01 00:00:00
abstract：:The quest for effective strategies to treat obesity has propelled fat research into an exploration of the molecular processes that drive adipocyte formation, and hence body fat mass. The development of obesity is dependent on the coordinated interplay of adipocyte hypertrophy (increased fat cell size), adipocyte hyper...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2006.06.022
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:Excess cathelicidin and kallikrein 5 (KLK5) have been hypothesized to play a role in the pathophysiology of rosacea. OBJECTIVE:We sought to evaluate the effects of azelaic acid (AzA) on these elements of the innate immune system. METHODS:Gene expression and protease activity were measured in laboratory mod...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jaad.2013.05.019
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:The co-existence of hidradenitis suppurativa (HS) and atopic dermatitis (AD) had been reported but was not investigated in controlled studies. OBJECTIVE:To evaluate the bidirectional association between HS and AD. METHODS:A population-based retrospective cohort study was conducted to compare incidence rate...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2020.12.051
更新日期：2020-12-27 00:00:00
abstract：:A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(88)70274-1
更新日期：1988-12-01 00:00:00
abstract：:Subungual Bowen's disease and squamous cell carcinoma are not as rare as has been implied by earlier literature. The course of the lesions is protracted. Clinically the diseases may mimic onychomycosis, chronic paronychia, eczema, verruca vulgaris, pyogenic granuloma, subungual exostosis, or malignant melanoma. Histol...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(84)70165-4
更新日期：1984-08-01 00:00:00
