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Aphthous ulcers associated with imiquimod and the treatment of actinic cheilitis.

Abstract：

:Our case series report is the first documented depiction of the appearance of aphthous ulcers secondary to imiquimod application. This case series presentation discusses the underlying pathophysiology of aphthous ulcer development and imiquimod therapy in terms of the stimulation of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-alpha). The literature review suggests more than just a mere coincidence for the development of aphthous ulcers subsequent to the treatment of actinic cheilitis with imiquimod application.

journal_name

J Am Acad Dermatol

journal_title

Journal of the American Academy of Dermatology

authors

Chakrabarty AK,Mraz S,Geisse JK,Anderson NJ

doi

10.1016/j.jaad.2004.06.045

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

35-7

issue

2 Suppl 1

eissn

0190-9622

issn

1097-6787

pii

S0190962204018572

journal_volume

52

pub_type

杂志文章

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