Herpes zoster in children.

Abstract:

BACKGROUND:The clinical studies of series of children with herpes zoster (HZ) are rather limited. OBJECTIVE:The purpose of this study was to evaluate the epidemiologic conditions, clinical manifestations, therapy, and outcome of HZ in children. METHODS:Twenty-one patients with HZ have been studied. Five patients who had herpes simplex virus infection were excluded. The laboratory diagnosis was made by fluorescent techniques. Acyclovir was administered systematically for 2 more days after no new lesions had developed. RESULTS:Thirteen patients (group A) were immunocompromised; eight patients (group B) were otherwise healthy. Two patients from group B had intrauterine varicella; the other six patients had had varicella under the age of 4 years. Three patients were recently exposed to varicella. The duration of HZ was significantly longer in group A than in group B, but the outcome was good in all patients. CONCLUSION:Herpes simplex virus infection may simulate the pattern of HZ; varicella in early childhood is a risk factor for HZ in otherwise healthy children; exposure of a child to varicella may cause reactivation of latent HZ virus; and acyclovir therapy within 3 days of exanthem onset prevents significant morbidity and death in immunocompromised children with HZ.

journal_name

J Am Acad Dermatol

authors

Kakourou T,Theodoridou M,Mostrou G,Syriopoulou V,Papadogeorgaki H,Constantopoulos A

doi

10.1016/s0190-9622(98)70076-3

subject

Has Abstract

pub_date

1998-08-01 00:00:00

pages

207-10

issue

2 Pt 1

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(98)70076-3

journal_volume

39

pub_type

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