Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts.

Abstract:

:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sharing multicenter-based evidences for therapeutic efforts is the lack of generally accepted definitions for the clinical evaluation of patients with BP. Common terms and end points of BP are needed so that experts in the field can accurately measure and assess disease extent, activity, severity, and therapeutic response, and thus facilitate and advance clinical trials. These recommendations from the International Pemphigoid Committee represent 2 years of collaborative efforts to attain mutually acceptable common definitions for BP and proposes a disease extent score, the BP Disease Area Index. These items should assist in the development of consistent reporting of outcomes in future BP reports and studies.

journal_name

J Am Acad Dermatol

authors

Murrell DF,Daniel BS,Joly P,Borradori L,Amagai M,Hashimoto T,Caux F,Marinovic B,Sinha AA,Hertl M,Bernard P,Sirois D,Cianchini G,Fairley JA,Jonkman MF,Pandya AG,Rubenstein D,Zillikens D,Payne AS,Woodley D,Zambruno

doi

10.1016/j.jaad.2011.06.032

subject

Has Abstract

pub_date

2012-03-01 00:00:00

pages

479-85

issue

3

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(11)00840-1

journal_volume

66

pub_type

共识发展会议,杂志文章
  • Diagnosis and management of nail pigmentations.

    abstract::Longitudinal pigmentation of the nail is very common. The differential diagnosis varies from subungual hematoma, to a fungal infection, to a melanocytic lesion (lentigo, nevus melanoma, etc.) to others. Often, dermatologists do not feel at ease with these pathologies and management is often not clear. In many cases, a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2006.12.021

    authors: Braun RP,Baran R,Le Gal FA,Dalle S,Ronger S,Pandolfi R,Gaide O,French LE,Laugier P,Saurat JH,Marghoob AA,Thomas L

    更新日期:2007-05-01 00:00:00

  • Narrowband ultraviolet B and medium-dose ultraviolet A1 are equally effective in the treatment of moderate to severe atopic dermatitis.

    abstract:BACKGROUND:Phototherapy may be effective in atopic dermatitis (AD). Medium-dose (MD) ultraviolet (UV) A1 was introduced for the treatment of AD. Few immunohistochemical data are available pertaining to phototherapy in AD. Regulatory T cells may play a role in clearing AD. OBJECTIVES:We sought to compare the clinical a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jaad.2008.08.048

    authors: Majoie IM,Oldhoff JM,van Weelden H,Laaper-Ertmann M,Bousema MT,Sigurdsson V,Knol EF,Bruijnzeel-Koomen CA,de Bruin-Weller MS

    更新日期:2009-01-01 00:00:00

  • Association between itch and cancer in 16,925 patients with pruritus: Experience at a tertiary care center.

    abstract:BACKGROUND:Pruritus has been associated with cancer. However, limited data are available on the types of underlying malignancies associated with pruritus. OBJECTIVE:We sought to characterize the association between pruritus and different cancer types, as well as variations by racial group. METHODS:Cross-sectional stu...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2018.08.044

    authors: Larson VA,Tang O,Ständer S,Kang S,Kwatra SG

    更新日期:2019-04-01 00:00:00

  • The pathogenesis of psoriasis and the mechanism of action of tazarotene.

    abstract::The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(98)70309-3

    authors: Duvic M,Asano AT,Hager C,Mays S

    更新日期:1998-10-01 00:00:00

  • A clinical and histologic comparison of electrosurgical and carbon dioxide laser peels.

    abstract:BACKGROUND:A radiofrequency-controlled electrosurgical device (ESD) has been adapted for skin peeling. A high-voltage, low-amperage current converts an irrigant into an ionized vapor, causing molecular dissociation and superficial damage in adjacent tissue. OBJECTIVE:We compared the clinical and histologic effects of ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1067/mjd.2001.109856

    authors: Acland KM,Calonje E,Seed PT,Stat C,Barlow RJ

    更新日期:2001-03-01 00:00:00

  • Vasculitis in erythema induratum of Bazin: a histopathologic study of 101 biopsy specimens from 86 patients.

    abstract:BACKGROUND:Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2008.07.030

    authors: Segura S,Pujol RM,Trindade F,Requena L

    更新日期:2008-11-01 00:00:00

  • Application of Mohs micrographic surgery appropriate-use criteria to skin cancers at a university health system.

    abstract:BACKGROUND:Mohs micrographic surgery (MMS) is an effective treatment for skin cancer. Until recently, it has been difficult to determine the percentage of skin cancers best treated with MMS. The appropriate-use criteria represents an opportunity to more accurately estimate this number. OBJECTIVE:We sought to apply the...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2014.02.025

    authors: Blechman AB,Patterson JW,Russell MA

    更新日期:2014-07-01 00:00:00

  • History, pharmacokinetics, and pharmacology of acyclovir.

    abstract::A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 历史文章,杂志文章

    doi:10.1016/s0190-9622(88)70022-5

    authors: King DH

    更新日期:1988-01-01 00:00:00

  • Racial and ethnic differences in health care utilization for childhood eczema: An analysis of the 2001-2013 Medical Expenditure Panel Surveys.

    abstract:BACKGROUND:Eczema is a common chronic inflammatory disease of the skin. Studies suggest differences in disease prevalence and severity by race/ethnicity. Our knowledge of health care utilization for eczema among different racial/ethnic groups remains limited. OBJECTIVE:To evaluate health care utilization for childhood...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2017.08.035

    authors: Fischer AH,Shin DB,Margolis DJ,Takeshita J

    更新日期:2017-12-01 00:00:00

  • A pilot study assessing the role of 25 hydroxy vitamin D levels in patients with vitiligo vulgaris.

    abstract:BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2009.11.024

    authors: Silverberg JI,Silverberg AI,Malka E,Silverberg NB

    更新日期:2010-06-01 00:00:00

  • Neutrophilic eccrine hidradenitis in two neutropenic patients.

    abstract::Neutrophilic eccrine hidradenitis is an uncommon, self-limited dermatosis with a variable clinical presentation. It seems to be due to chemotherapeutic drugs in most cases. Necrosis of the eccrine gland associated with a neutrophilic infiltrate is the histologic hallmark of this disease. We report two additional cases...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(90)70342-f

    authors: Allegue F,Soria C,Rocamora A,Muñoz E,Freire-Murgueytio P,Arrazola JM,Ledo A

    更新日期:1990-12-01 00:00:00

  • Conformational epitope mapping and IgG subclass distribution of desmoglein 3 in paraneoplastic pemphigus.

    abstract:BACKGROUND:Pemphigus vulgaris (PV) shows autoimmune reaction against desmoglein 3 (Dsg3), whereas paraneoplastic pemphigus (PNP) shows autoimmune reaction against Dsg3 as well as numerous members of the plakin family. It has been demonstrated that in PV, dominant epitopes reside in N-terminal adhesive regions of Dsg3 a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(03)02160-1

    authors: Futei Y,Amagai M,Hashimoto T,Nishikawa T

    更新日期:2003-12-01 00:00:00

  • Topical rapamycin combined with pulsed dye laser in the treatment of capillary vascular malformations in Sturge-Weber syndrome: phase II, randomized, double-blind, intraindividual placebo-controlled clinical trial.

    abstract:BACKGROUND:Sturge-Weber syndrome (SWS) is characterized by port-wine stains (PWS) affecting the face, eyes, and central nervous system. Pulsed dye laser (PDL) is the standard treatment for PWS. Unfortunately, recurrence is frequent because of reformation and reperfusion of blood vessels. OBJECTIVE:We sought to assess ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jaad.2014.10.011

    authors: Marqués L,Núñez-Córdoba JM,Aguado L,Pretel M,Boixeda P,Nagore E,Baselga E,Redondo P

    更新日期:2015-01-01 00:00:00

  • Isolated plantar collagenoma not associated with Proteus syndrome.

    abstract::Isolated plantar cerebriform collagenomas are a relatively rare type of connective tissue nevus. They have been suggested to be pathognomonic of Proteus syndrome. However, their presence is now considered to be a major criterion of Proteus syndrome, but the diagnosis of Proteus syndrome also requires the presence of o...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2007.03.016

    authors: Nelson AA,Ruben BS

    更新日期:2008-03-01 00:00:00

  • Contact dermatitis from Larrea (creosote bush).

    abstract::Six men suffering from acute dermatitis had positive patch tests to Larrea (creosote bush). The lesions preferentially involved sun-exposed sites, simulating a photodermatitis, but also were on the legs and scrotum. Our findings were more consistent with contact allergy than with a primary irritant or a phototoxic res...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(86)70022-4

    authors: Leonforte JF

    更新日期:1986-02-01 00:00:00

  • Clinical and histologic features of incontinentia pigmenti in adults with nuclear factor-κB essential modulator gene mutations.

    abstract:BACKGROUND:Incontinentia pigmenti (IP) is a multisystem disorder, in which cutaneous symptoms can be accompanied by dental, ocular, and central nervous system defects. In adults, the clinical diagnosis of IP is based principally on the late onset of stage 4 lesions and their association with dental, nail, ocular, or ce...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2010.01.045

    authors: Hadj-Rabia S,Rimella A,Smahi A,Fraitag S,Hamel-Teillac D,Bonnefont JP,de Prost Y,Bodemer C

    更新日期:2011-03-01 00:00:00

  • Eutectic lidocaine/prilocaine 5% cream and patch may provide satisfactory analgesia for excisional biopsy or curettage with electrosurgery of cutaneous lesions. A randomized, controlled, parallel group study.

    abstract:BACKGROUND:Needle puncture and infiltrational anesthesia is generally required for minor cutaneous surgical procedures and may be associated with anxiety, fear, discomfort, and pain. The use of topical anesthetics such as eutectic lidocaine/prilocaine 5% cream may provide an alternative means of delivering anesthesia. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0190-9622(96)90608-8

    authors: Gupta AK,Sibbald RG

    更新日期:1996-09-01 00:00:00

  • Efficacy of tan accelerators.

    abstract::A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(87)70099-1

    authors: Jaworsky C,Ratz JL,Dijkstra JW

    更新日期:1987-04-01 00:00:00

  • Efficacy and safety of antiscabietic agents: A systematic review and network meta-analysis of randomized controlled trials.

    abstract:BACKGROUND:Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious. OBJECTIVE:To evaluate the comparative efficacy and safety of antiscabietic agents. METHODS:A systematic review of randomized controlled trials was conducted. Direct and network meta-analyses were applied to...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jaad.2019.01.004

    authors: Thadanipon K,Anothaisintawee T,Rattanasiri S,Thakkinstian A,Attia J

    更新日期:2019-05-01 00:00:00

  • Pediatric melanoma: results of a large cohort study and proposal for modified ABCD detection criteria for children.

    abstract:BACKGROUND:Clinical and histopathologic features of childhood melanoma are poorly characterized. Atypical clinical presentations and ambiguous microscopic findings may contribute to diagnostic delays. OBJECTIVES:We sought to determine whether conventional ABCDE melanoma detection criteria (Asymmetry, Border irregulari...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2012.12.953

    authors: Cordoro KM,Gupta D,Frieden IJ,McCalmont T,Kashani-Sabet M

    更新日期:2013-06-01 00:00:00

  • The skin as an immunologic organ. A tribute to Marion B. Sulzberger.

    abstract::The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70195-8

    authors: Katz SI

    更新日期:1985-09-01 00:00:00

  • Angioinvasive fungal infections impacting the skin: Diagnosis, management, and complications.

    abstract::As discussed in the first article in this continuing medical education series, angioinvasive fungal infections pose a significant risk to immunocompromised and immunocompetent patients alike, with a potential for severe morbidity and high mortality. The first article in this series focused on the epidemiology and clin...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2018.04.058

    authors: Berger AP,Ford BA,Brown-Joel Z,Shields BE,Rosenbach M,Wanat KA

    更新日期:2019-04-01 00:00:00

  • Subcutaneous fat in normal and diseased states: 1. Introduction.

    abstract::In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions....

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.05.014

    authors: Avram MM,Avram AS,James WD

    更新日期:2005-10-01 00:00:00

  • CD2- CD4+ CD56+ hematodermic/hematolymphoid malignancy.

    abstract:BACKGROUND:CD2- CD4+ CD56+ lymphoid malignancy has been only rarely reported the last 5 years. It is characterized by a high incidence of cutaneous involvement, cytologically agranular cells, aggressive clinical course, and negative Epstein-Barr virus (EBV) involvement. OBSERVATION:We describe a Japanese patient with ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1067/mjd.2001.110897

    authors: Kato N,Yasukawa K,Kimura K,Sugawara H,Aoyagi S,Mishina T,Nakata T

    更新日期:2001-02-01 00:00:00

  • Sunny days, healthy ways: evaluation of a skin cancer prevention curriculum for elementary school-aged children.

    abstract:BACKGROUND:Primary prevention of skin cancer must start early in life to reduce total life-time sun exposure and severe overexposure in childhood. Childhood is an excellent time to form life-long prevention habits. A school-based curriculum can be an effective prevention strategy. OBJECTIVE:Our purpose was to determin...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(96)90115-2

    authors: Buller DB,Buller MK,Beach B,Ertl G

    更新日期:1996-12-01 00:00:00

  • Melanocytic nevus with pregnancy-related changes in size accompanied by apoptosis of nevus cells: a case report.

    abstract::Melanocytic nevi are commonly believed to undergo changes during pregnancy. This is probably related to hormonal influences; however, few studies have been able to prove it. We observed a case of a benign melanocytic nevus, which showed significant enlargement during pregnancy and immediate postpartum regression assoc...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(00)90277-9

    authors: Lee HJ,Ha SJ,Lee SJ,Kim JW

    更新日期:2000-05-01 00:00:00

  • Comorbidities significantly impact patients' preferences for psoriasis treatments.

    abstract:BACKGROUND:Non-adherence rates are high among patients with psoriasis, partly because of discordance between recommended treatments and individual preferences. OBJECTIVES:Our aim was to assess the impact of comorbidities on patients' preferences for psoriasis treatments. METHODS:A computer-based conjoint analysis exp...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2011.08.023

    authors: Schmieder A,Schaarschmidt ML,Umar N,Terris DD,Goebeler M,Goerdt S,Peitsch WK

    更新日期:2012-09-01 00:00:00

  • Hereditary progressive mucinous histiocytosis.

    abstract::We describe hereditary progressive mucinous histiocytosis, a rare autosomal dominant non-Langerhans cell histiocytosis, in a mother and daughter. Both had similar, progressive eruptions of skin-colored to red-brown papules on the nose, hands, forearms, and thighs. Light microscopy showed small collections of epithelio...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(96)90653-2

    authors: Schröder K,Hettmannsperger U,Schmuth M,Orfanos CE,Goerdt S

    更新日期:1996-08-01 00:00:00

  • Disadhesion of epidermal keratinocytes: a histologic clue to palmoplantar keratodermas caused by DSG1 mutations.

    abstract:BACKGROUND:Recent developments in molecular genetics may lead to re-examination of the histopathology of inherited palmoplantar keratodermas (PPKs) based on more precise groupings of the various entities and syndromes. OBJECTIVE:We sought to characterize the histopathological findings in PPKs associated with mutations...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2009.05.016

    authors: Bergman R,Hershkovitz D,Fuchs D,Indelman M,Gadot Y,Sprecher E

    更新日期:2010-01-01 00:00:00

  • Use of monoclonal antibodies (UCHL1, Ki-B3) against T and B cell antigens in routine paraffin-embedded skin biopsy specimens.

    abstract::Diagnosis and classification of cutaneous lymphoid infiltrates are often hampered by lack of frozen tissue to allow detailed immunophenotyping. Therefore antibodies that recognize antigens resistant to routine tissue processing would be of value. In this study we present a detailed analysis of two such antibodies agai...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)70155-9

    authors: Sterry W,Hauschild A

    更新日期:1989-07-01 00:00:00