Contact dermatitis from Larrea (creosote bush).

abstract：BACKGROUND:Recent developments in molecular genetics may lead to re-examination of the histopathology of inherited palmoplantar keratodermas (PPKs) based on more precise groupings of the various entities and syndromes. OBJECTIVE:We sought to characterize the histopathological findings in PPKs associated with mutations...

journal_title：Journal of the American Academy of Dermatology

authors： Bergman R,Hershkovitz D,Fuchs D,Indelman M,Gadot Y,Sprecher E

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:In infantile seborrheic dermatitis (ISD) several different pathogenetic mechanisms have been proposed. OBJECTIVE:The purpose of the study was to investigate the importance of essential fatty acids (EFAs) and their metabolites in the origin of ISD. METHODS:The serum EFA patterns of 30 children with ISD, 1 t...

journal_title：Journal of the American Academy of Dermatology

authors： Tollesson A,Frithz A,Berg A,Karlman G

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Significant unmet need exists for long-term treatment of moderate to severe atopic dermatitis (AD). OBJECTIVE:To assess the long-term safety and efficacy of dupilumab in patients with AD. METHODS:This ongoing, multicenter, open-label extension study (NCT01949311) evaluated long-term dupilumab treatment in ...

journal_title：Journal of the American Academy of Dermatology

authors： Deleuran M,Thaçi D,Beck LA,de Bruin-Weller M,Blauvelt A,Forman S,Bissonnette R,Reich K,Soong W,Hussain I,Foley P,Hide M,Bouaziz JD,Gelfand JM,Sher L,Schuttelaar MLA,Wang C,Chen Z,Akinlade B,Gadkari A,Eckert L,Da

更新日期：2020-02-01 00:00:00

abstract：:Good to excellent clinical results have been obtained in the treatment of severe inflammatory acne (acne conglobata, acne fulminans, and acne conglobata with hidradenitis and dissecting cellulitis of the scalp) with orally administered isotretinoin (13-cis-retinoic acid). Similar promising results have been obtained i...

journal_title：Journal of the American Academy of Dermatology

authors： Plewig G,Nikolowski J,Wolff HH

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:The prognostic relevance of a high blood neutrophil-to-lymphocyte ratio (NLR) has been reported in many cancers, although, to our knowledge, not investigated in patients with Merkel cell carcinoma (MCC) to date. OBJECTIVE:We assessed whether the NLR at baseline was associated with specific survival and recu...

journal_title：Journal of the American Academy of Dermatology

authors： Zaragoza J,Kervarrec T,Touzé A,Avenel-Audran M,Beneton N,Esteve E,Wierzbicka Hainaut E,Aubin F,Machet L,Samimi M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Paradoxical hidradenitis suppurativa (HS) induced by biologic agents (BA) is scarcely reported. OBJECTIVE:We sought to describe the clinical characteristics and outcome of patients developing paradoxical HS under BA. METHODS:This was a multicenter nationwide retrospective study asking physicians to report ...

journal_title：Journal of the American Academy of Dermatology

authors： Faivre C,Villani AP,Aubin F,Lipsker D,Bottaro M,Cohen JD,Durupt F,Jeudy G,Sbidian E,Toussirot E,Badot V,Barbarot S,Debarbieux S,Delaporte E,Goegebeur G,Morel J,Nassif A,Duru G,Jullien D,French Society of Dermatology

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:For persons of childbearing potential prescribed isotretinoin, the iPLEDGE program requires use of 2 simultaneous methods of contraception or commitment to abstinence. OBJECTIVE:To model the relative effectiveness of a variety of contraception strategies for patients taking isotretinoin, including those tha...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,Roe AH,Mostaghimi A

更新日期：2020-07-01 00:00:00

abstract：:Lymphomatoid papulosis is a chronic disease of cutaneous lymphoid infiltration characterized clinically by involuting and recurring papules, plaques, and nodules. The intriguing combination of a usually benign clinical course, a cytologically malignant lymphoid infiltrate on histologic examination, and a clear, but sp...

journal_title：Journal of the American Academy of Dermatology

authors： Karp DL,Horn TD

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Facial erythema is a clinical hallmark of rosacea and often causes social and psychological distress. Although facial erythema assessments are a common endpoint in rosacea clinical trials, their reliability has not been evaluated. OBJECTIVE:The objective of this study was to evaluate the inter- and intrarat...

journal_title：Journal of the American Academy of Dermatology

authors： Tan J,Liu H,Leyden JJ,Leoni MJ

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The current standard tool for diagnosing allergic contact dermatitis (ACD) in the United States is the T.R.U.E. test panels, which consist of 23 allergens. Previous studies have raised concern regarding the adequacy of these panels in fully assessing patients with possible ACD. OBJECTIVE:We sought to examin...

journal_title：Journal of the American Academy of Dermatology

authors： Saripalli YV,Achen F,Belsito DV

更新日期：2003-07-01 00:00:00

abstract：:In recent years, our understanding of adipose tissue physiology and function has undergone an enormous transformation. Once considered a passive storage receptacle with a fixed number of cells and limited purpose, adipose tissue is now recognized as a complicated organ with important endocrine and metabolic functions....

journal_title：Journal of the American Academy of Dermatology

authors： Avram MM,Avram AS,James WD

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a recurrent hemorrhagic papular skin eruption with a clinically benign course and histopathologic features of lymphoma. OBJECTIVE AND METHODS:To better characterize this disease, we studied 53 patients seen since 1965. RESULTS:A lymphoproliferative malignancy developed withi...

journal_title：Journal of the American Academy of Dermatology

authors： el-Azhary RA,Gibson LE,Kurtin PJ,Pittelkow MR,Muller SA

更新日期：1994-02-01 00:00:00

abstract：OBJECTIVE:We sought to determine what clinical features of psoriasis predict sleep interference. METHODS:Data were obtained from 420 respondents to the 2005 National Psoriasis Foundation telephone and e-mail surveys. Logistic regression was used to determine whether disease severity, body mass index, age of onset, pso...

journal_title：Journal of the American Academy of Dermatology

authors： Callis Duffin K,Wong B,Horn EJ,Krueger GG

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Few data exist on the relationship between psoriasis and melanocytic lesions. OBJECTIVES:We sought to investigate number of melanocytic nevi in psoriatic patients compared with control subjects and its relationship with disease severity and treatment. METHODS:We performed a prospective study in 189 psoriat...

journal_title：Journal of the American Academy of Dermatology

authors： Di Cesare A,Riitano A,Suppa M,Fidanza R,Zangrilli A,Esposito M,Fargnoli MC,Chimenti S,Peris K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The formulation of topical dermatologic products must take into account efficacy, safety, and patient compliance. OBJECTIVE:We describe how an aqueous gel containing adapalene, a novel naphthoic acid derivative was selected for the topical treatment of acne. METHODS AND RESULTS:Dose selection was made usin...

journal_title：Journal of the American Academy of Dermatology

authors： Allec J,Chatelus A,Wagner N

更新日期：1997-06-01 00:00:00

abstract：:Subacute myelomonocytic leukemia is typically preceded by a preleukemic phase lasting 1 to 10 years. We describe a case of subacute myelomonocytic leukemia preceded by pruritus for 7 years and by the intermittent appearance of nonspecific necrotic dermal nodules for 4 years. ...

journal_title：Journal of the American Academy of Dermatology

authors： Peterson AO Jr,Jarratt M

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：:Long-term penicillamine therapy has been associated with alterations in dermal elastic tissue. Well-described associated dermatoses include pseudo-pseudoxanthoma elasticum, acquired cutis laxa, elastosis perforans serpiginosa, and anetoderma. Histologically, "lumpy-bumpy" or "bramble-bush" morphologic changes of elast...

journal_title：Journal of the American Academy of Dermatology

authors： Lewis BK,Chern PL,Stone MS

更新日期：2009-04-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：:As discussed in the first article in this continuing medical education series, angioinvasive fungal infections pose a significant risk to immunocompromised and immunocompetent patients alike, with a potential for severe morbidity and high mortality. The first article in this series focused on the epidemiology and clin...

journal_title：Journal of the American Academy of Dermatology

authors： Berger AP,Ford BA,Brown-Joel Z,Shields BE,Rosenbach M,Wanat KA

更新日期：2019-04-01 00:00:00

abstract：:Nodular primary localized cutaneous amyloidosis is an uncommon disorder for which there is no consistently satisfactory treatment. The amyloid fibrils are thought to have an immunoglobulin light chain derivation and systemic involvement must be excluded in all cases. We report a patient with a large scalp lesion of no...

journal_title：Journal of the American Academy of Dermatology

authors： Truhan AP,Garden JM,Roenigk HH Jr

更新日期：1986-06-01 00:00:00

abstract：:We present the case of an American adult patient with eosinophilic pustular folliculitis. The majority of previously reported patients have been Japanese. Eosinophilic pustular folliculitis is a rare condition characterized by recurrent, peripherally expanding, sterile papulopustules and plaques. Hair-bearing areas su...

journal_title：Journal of the American Academy of Dermatology

authors： Jaliman HD,Phelps RG,Fleischmajer R

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Dermatomyositis affects visible skin and causes disease symptoms that can affect patients' quality of life (QOL). METHODS:In all, 71 patients with dermatomyositis or dermatomyositis sine myositis completed two QOL measures (the Skindex-16 and the Dermatology Life Quality Index) and a visual analog scale for...

journal_title：Journal of the American Academy of Dermatology

authors： Hundley JL,Carroll CL,Lang W,Snively B,Yosipovitch G,Feldman SR,Jorizzo JL

更新日期：2006-02-01 00:00:00

abstract：:We present the identification and characterization of two patients with xeroderma pigmentosum (XP) and squamous cell carcinoma of the tongue. Dermal fibroblasts from two black siblings with XP were shown to be hypersensitive to ultraviolet (UV) light measured by colony-forming ability. UV-induced unscheduled deoxyribo...

journal_title：Journal of the American Academy of Dermatology

authors： Wade MH,Plotnick H

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Necrolytic migratory erythema (NME) is an uncommon inflammatory dermatosis with a distinct clinical and histologic appearance. NME is usually associated with glucagonoma. Only a few cases of NME in the absence of glucagonoma have been previously reported. OBJECTIVE:We sought to understand further the pathog...

journal_title：Journal of the American Academy of Dermatology

authors： Marinkovich MP,Botella R,Datloff J,Sangueza OP

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Yao Z,Polsky D,Jansen B,Busam K,Ho J,Martini M,Ferris LK

更新日期：2017-01-01 00:00:00

abstract：:The number of physicians who provide ambulatory care for patients with skin diseases is rapidly increasing. Current and proposed changes in health care financing may limit direct access to dermatologists. We provide recent data on volume of visits for cutaneous diagnoses, including the types of medical practitioners w...

journal_title：Journal of the American Academy of Dermatology

authors： Stern RS,Nelson C

更新日期：1993-11-01 00:00:00

abstract：:Granuloma annulare typically affects the hands and the feet, sparing the volar surfaces. A case of granuloma annulare localized to the palms is described. ...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu S,Lehner AC,Chang JR

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The risk of acquiring Lyme disease has been evaluated by xenodiagnostic procedures with laboratory strains of Borrelia burgdorferi and laboratory-reared Ixodes ticks, or by clinical trials in which diagnosis was based on clinical findings, culture, or serologic tests. OBJECTIVE:Our purpose was to determine ...

journal_title：Journal of the American Academy of Dermatology

authors： Berger BW,Johnson RC,Kodner C,Coleman L

更新日期：1995-02-01 00:00:00