Action of isotretinoin in acne rosacea and gram-negative folliculitis.

abstract：BACKGROUND:Mohs micrographic surgery is thought to be a useful therapy for cutaneous melanoma. Controversy persists, however, because there are few published reports that document its safety and efficacy. OBJECTIVE:Our purpose was to determine the safety and efficacy of Mohs micrographic surgery for the treatment of c...

journal_title：Journal of the American Academy of Dermatology

authors： Zitelli JA,Brown C,Hanusa BH

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a cyclic papulonodular eruption that is clinically benign and histologically malignant. Association with hematologic neoplasias has been reported in 5% to 20% of all cases. OBJECTIVE:We sought to review the clinical and histopathologic features of LyP in pediatric patients. ...

journal_title：Journal of the American Academy of Dermatology

authors： de Souza A,Camilleri MJ,Wada DA,Appert DL,Gibson LE,el-Azhary RA

更新日期：2009-12-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:A tumor is reported that had remarkable pathologic changes showing with light microscopy a pattern in some portions consistent with tubular apocrine adenoma, while other areas were suggestive of syringoid eccrine carcinoma. Perineural invasion, commonly seen in syringoid eccrine carcinoma and never before reported in ...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Zelickson AS

更新日期：1984-10-01 00:00:00

abstract：:We describe a patient with zygomycosis that resembled herpes zoster infection. The diagnosis was readily made with a potassium hydroxide preparation that revealed sparsely to non-septate hyphae. The patient responded to combination antifungal therapy with amphotericin B and fluconazole. The clinical response correlate...

journal_title：Journal of the American Academy of Dermatology

authors： Woods SG,Elewski BE

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Desonide, a class 6 nonfluorinated topical corticosteroid, has been available for more than two decades. Hydrocortisone is widely used in the treatment of dermatoses in children. OBJECTIVE:Our purpose was to compare the safety and efficacy of desonide ointment and 1.0% hydrocortisone ointment in children wi...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo J,Levy M,Lucky A,Shavin J,Goldberg G,Dunlap F,Hinds A,Strelka L,Baker M,Tuley M

更新日期：1995-07-01 00:00:00

abstract：:Rosacea is a skin condition of abnormal inflammation and vascular dysfunction. The active contribution of a microbial agent in the development or progression of rosacea continues to be debated. Research supports the presence of commensal Demodex folliculorum mites at increased density in the skin and associates Helico...

journal_title：Journal of the American Academy of Dermatology

authors： Holmes AD

更新日期：2013-12-01 00:00:00

abstract：:Six patients with lymphomatoid papulosis demonstrated a clonal T-cell population in skin lesions by polymerase chain reaction methods. Two of these patients showed identical T-cell clones in their peripheral blood T cells as well. In one case, the clone persisted in the blood despite clearing of skin lesions with meth...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz JC,Granados S,Vonderheid EC,Hwang ST

更新日期：2005-07-01 00:00:00

abstract：LEARNING OBJECTIVES:At the conclusion of this learning activity, physician participants should be able to assess their own diagnostic and patient management skills and use the results of this exercise to help determine personal learning needs. Instructions: In answering each question, refer to the specific directions p...

journal_title：Journal of the American Academy of Dermatology

authors： Hung CT,Wang WM

更新日期：2015-11-01 00:00:00

abstract：:Several technics for immunofluorescent staining have been described in the literature and are presently used by laboratories performing direct and indirect tissue immunofluorescence. The purpose of this communication is to describe a simple immunofluorescent technic that uses a five-slide polypropylene slide mailer co...

journal_title：Journal of the American Academy of Dermatology

authors： Grimwood RE,Huff JC,Weston W

更新日期：1985-11-01 00:00:00

abstract：:Six men suffering from acute dermatitis had positive patch tests to Larrea (creosote bush). The lesions preferentially involved sun-exposed sites, simulating a photodermatitis, but also were on the legs and scrotum. Our findings were more consistent with contact allergy than with a primary irritant or a phototoxic res...

journal_title：Journal of the American Academy of Dermatology

authors： Leonforte JF

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. OBJECTIVE:We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. METHODS:Patients with 1267 consecutivel...

journal_title：Journal of the American Academy of Dermatology

authors： Schulte KW,Lippold A,Auras C,Bramkamp G,Breitkopf C,Elsmann HJ,Habenicht EM,Jasnoch V,Müller-Pannes H,Rupprecht R,Suter L

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Nonmelanoma skin cancer (NMSC) incidence in patients with vitiligo has not been studied. OBJECTIVE:We sought to quantify the incidence of NMSC in patients with vitiligo. METHODS:A cohort of 477 patients with vitiligo and no history of NMSC seen in an outpatient academic center between January 2001 and Dece...

journal_title：Journal of the American Academy of Dermatology

authors： Hexsel CL,Eide MJ,Johnson CC,Krajenta R,Jacobsen G,Hamzavi I,Lim HW

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

journal_title：Journal of the American Academy of Dermatology

authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Junctional nevi are traditionally associated with children and younger patients. We noticed that these lesions are also often found in elderly patients. OBJECTIVE:We sought to determine if junctional nevi are found in all age groups. METHODS:All biopsy reports for junctional nevi for the year 2001 at the P...

journal_title：Journal of the American Academy of Dermatology

authors： Westhafer J,Gildea J,Klepeiss S,Clarke L,Helm K

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE:This study was conducted to evaluate the efficacy and safety of BTX-A treatment of glabellar lines. METHODS:Patients with moderate to severe glabellar lines at maximum frown received intramuscular inje...

journal_title：Journal of the American Academy of Dermatology

authors： Carruthers JA,Lowe NJ,Menter MA,Gibson J,Nordquist M,Mordaunt J,Walker P,Eadie N,BOTOX Glabellar Lines I Study Group.

更新日期：2002-06-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/j.jaad.2020.09.006. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/...

journal_title：Journal of the American Academy of Dermatology

authors： Elston DM

更新日期：2020-09-14 00:00:00

abstract：:Three young and middle-aged patients developed severe bullous eruption after receiving various penicillins. The clinical findings included high fever, prostration, widespread bullous eruption mainly on the head, face, and extremities, targetlike lesions on the palms and soles, and severe erosions in almost all the muc...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,David M,Ingber A,Hazaz B,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：:Pharmacologic blockade of TNFalpha has been a highly effective approach to treating several immunologically mediated diseases, including rheumatoid arthritis, Crohn's disease, and psoriatic arthritis. 1,2,3 Both etanercept, the recombinant extracellular domain of the tumor necrosis factor receptor 2 (TNFR2), and infli...

journal_title：Journal of the American Academy of Dermatology

authors： Adams AE,Zwicker J,Curiel C,Kadin ME,Falchuk KR,Drews R,Kupper TS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Many targeted therapies used in the treatment of cancer can lead to the development of xerosis, but the incidence and relative risk of xerosis have not been ascertained. OBJECTIVE:We conducted a systematic review and metaanalysis of clinical trials, to ascertain the incidence and risk of developing xerosis ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine J,Belum VR,Duran J,Ciccolini K,Schindler K,Wu S,Lacouture ME

更新日期：2015-04-01 00:00:00

abstract：:The Americans With Disabilities Act (ADA) defines disability as a physical or mental impairment that substantially limits one or more major life activities. Although dermatology has received relatively little attention in the context of disability law, dermatologic diseases are properly covered by the ADA and are subj...

journal_title：Journal of the American Academy of Dermatology

authors： Curry ML,Curry JA,Cockerell CJ

更新日期：2002-12-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Gottlieb A,Feldman SR,Van Voorhees AS,Leonardi CL,Gordon KB,Lebwohl M,Koo JY,Elmets CA,Korman NJ,Beutner KR,Bhushan R

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a chronic, highly pruritic skin disorder, impairs quality of life (QoL). Janus kinase inhibitors suppress inflammatory and pruritus-associated cytokine signaling in AD. OBJECTIVE:To report the effects of ruxolitinib (RUX) cream on itch and QoL in AD. METHODS:A total of 307 adult pat...

journal_title：Journal of the American Academy of Dermatology

authors： Kim BS,Sun K,Papp K,Venturanza M,Nasir A,Kuligowski ME

更新日期：2020-06-01 00:00:00

abstract：:The presence of the discoid lupus erythematosus (DLE) skin lesion in a patient with systemic lupus erythematosus (SLE) has been suggested to be a marker of less frequent and less severe renal disease. The clinical and laboratory features of seventeen patients who were seen in a dermatology practice and who had DLE as ...

journal_title：Journal of the American Academy of Dermatology

authors： Callen JP

更新日期：1985-02-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

journal_title：Journal of the American Academy of Dermatology

authors： Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Giant angiofibromas in patients with tuberous sclerosis complex (TSC) are rare. OBJECTIVE:We sought to report two patients who had TSC with unusually large and disfiguring facial angiofibromas and to identify underlying histopathologic changes that may possibly explain the clinical features. METHODS:We per...

journal_title：Journal of the American Academy of Dermatology

authors： Kacerovska D,Kerl K,Michal M,Filipova H,Vrtel R,Vanecek T,Zelenakova H,Kraus J,Kodet R,Kazakov DV

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Evidence on long-term dupilumab treatment for atopic dermatitis in daily practice is lacking. OBJECTIVE:To investigate patient characteristics, treatment aspects, effectiveness, and safety of up to 84 weeks of dupilumab treatment. METHODS:An observational prospective cohort study was conducted of patients ...

journal_title：Journal of the American Academy of Dermatology

authors： Bosma AL,de Wijs LEM,Hof MH,van Nieuwenhuizen BR,Gerbens LAA,Middelkamp-Hup MA,Hijnen D,Spuls PI

更新日期：2020-11-01 00:00:00

abstract：:In autosomal dominant skin disorders, a pronounced mosaic involvement may sometimes be found to be superimposed on the ordinary nonsegmental lesions. Such "type 2 segmental manifestation" reflects loss of heterozygosity occurring at an early developmental stage, giving rise to a cell clone that lacks the corresponding...

journal_title：Journal of the American Academy of Dermatology

authors： Happle R

更新日期：2010-01-01 00:00:00