Cutaneous symptoms of dermatomyositis significantly impact patients' quality of life.

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50% of nail disorders. Although several surveys have been conducted in different parts of the world, there have been no multicenter epidemiologic surveys of onychomycosis in North America. OBJECTIVE:A 12-center study was undertaken ...

journal_title：Journal of the American Academy of Dermatology

authors： Ghannoum MA,Hajjeh RA,Scher R,Konnikov N,Gupta AK,Summerbell R,Sullivan S,Daniel R,Krusinski P,Fleckman P,Rich P,Odom R,Aly R,Pariser D,Zaiac M,Rebell G,Lesher J,Gerlach B,Ponce-De-Leon GF,Ghannoum A,Warner J,Is

更新日期：2000-10-01 00:00:00

abstract：:The presence of mast cells, often in an activated state or increased numbers, has been noted in various cutaneous disorders. Recent studies suggest that mast cells are of primary importance in these conditions and their presence does not merely represent a secondary event. This review focuses on atopic dermatitis, con...

journal_title：Journal of the American Academy of Dermatology

authors： Rothe MJ,Nowak M,Kerdel FA

更新日期：1990-10-01 00:00:00

abstract：:A 9-year-old girl was initially seen with bilateral mildly pruritic plantar skin lesions. Skin biopsy demonstrated a superficial and deep perivascular lymphoid infiltrate with mucin but was not specific. Laboratory evaluation revealed a mildly elevated antinuclear antibody and mild leukopenia. Over the following year,...

journal_title：Journal of the American Academy of Dermatology

authors： Evans-Ramsey T,Frieden IJ

更新日期：2003-11-01 00:00:00

abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...

journal_title：Journal of the American Academy of Dermatology

authors： de Groot AC,Weyland JW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Women with stage I malignant melanoma (MM) have a survival advantage over men as judged by univariate analysis. However, on multivariate analysis, gender was found to be an independent predictor of survival in only 8 of 14 published studies. OBJECTIVE:This study attempts to explain the disparate findings fo...

journal_title：Journal of the American Academy of Dermatology

authors： Vossaert KA,Silverman MK,Kopf AW,Bart RS,Rigel DS,Friedman RJ,Levenstein M

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

journal_title：Journal of the American Academy of Dermatology

authors： Reinhold U,Seiter S,Ugurel S,Tilgen W

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Detection of melanoma by physicians via opportunistic surveillance during focused physical examinations may reduce mortality. Medical students may not encounter a clinical case of melanoma during a dermatology clerkship. OBJECTIVE:This study examined the proficiency of fourth-year University of Illinois at ...

journal_title：Journal of the American Academy of Dermatology

authors： Hernandez C,Mermelstein R,Robinson JK,Yudkowsky R

更新日期：2013-03-01 00:00:00

abstract：:This report reflects the best data available at the time the report was prepared, but caution should be exercised in interpreting the data; the results of future studies may require alteration of the conclusions or recommendations set forth in this report. ...

journal_title：Journal of the American Academy of Dermatology

authors： Miller OF 3rd,Phillips TJ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Patients with atopic dermatitis (AD) often have increased skin sensitivity and this symptom often worsens during stress. OBJECTIVE:We sought to find out whether patients with AD had stinging, and to identify the pathocausal neuroimmune mechanisms, including the role of stress. METHODS:In all, 25 patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Lonne-Rahm S,Berg M,Mårin P,Nordlind K

更新日期：2004-12-01 00:00:00

abstract：:Pustular cutaneous vasculitis results from a heterogeneous group of disorders characterized by pustules on purpuric bases. Although the cause of this group of conditions is diverse, the histopathologic picture of the lesions is the same, showing a Sweet's-like or leukocytoclastic vasculitis. These distinctive lesions ...

journal_title：Journal of the American Academy of Dermatology

authors： McNeely MC,Jorizzo JL,Solomon AR Jr,Schmalstieg FC,Cavallo T

更新日期：1986-05-01 00:00:00

abstract：:A 40-year-old man with severe psoriasis developed painless muscle stiffness coinciding with four successive courses of etretinate therapy. Peripheral nerve block extinguished the increased muscle tone. Our patient's symptoms resembled those of the stiff-man syndrome. Increased muscle tone is a potential side effect of...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Gilbert M,Cohen KA,Albers JW,Ball RD,Albin RL,Silverman A,Voorhees JJ

更新日期：1986-05-01 00:00:00

abstract：:At the International Consensus Conference for Cutaneous T-Cell Lymphoma (CTCL) Treatment Recommendations (held in Boston, Massachusetts, Oct. 1 and 2, 1994), international experts were asked to assess where consensus existed and to identify areas that required clinical research. We review the epidemiology, pathology, ...

journal_title：Journal of the American Academy of Dermatology

authors： Demierre MF,Foss FM,Koh HK

更新日期：1997-03-01 00:00:00

abstract：:A recent study demonstrated that hirsute women with irregular menses had higher levels of serum androgens that hirsute women with regular menses. To investigate this finding, we measured total testosterone, biologically active testosterone, free testosterone, androstenedione, dehydroepiandrosterone, and dehydroepiandr...

journal_title：Journal of the American Academy of Dermatology

authors： Salman K,Spielvogel RL,Miller JL,Rose LI

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Because of the relatively rare occurrence of malignant melanoma (MM) of the eyelid, prognostic factors in relation to survival in these patients have not been established. OBJECTIVE:Our purpose was to examine prognostic indicators in relation to survival in patients with MM of the eyelid. METHODS:All patie...

journal_title：Journal of the American Academy of Dermatology

authors： Tahery DP,Goldberg R,Moy RL

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Since publication in 2000 of the Second International Consensus Report on Diagnosis and Classification of Epidermolysis Bullosa, many advances have been made to our understanding of this group of diseases, both clinically and molecularly. At the same time, new epidermolysis bullosa (EB) subtypes have been de...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Eady RA,Bauer EA,Bauer JW,Bruckner-Tuderman L,Heagerty A,Hintner H,Hovnanian A,Jonkman MF,Leigh I,McGrath JA,Mellerio JE,Murrell DF,Shimizu H,Uitto J,Vahlquist A,Woodley D,Zambruno G

更新日期：2008-06-01 00:00:00

abstract：:Polymorphous sweat gland carcinoma is an unusual, recently described variant of low-grade malignant adnexal neoplasm of the skin characterized by a prolonged clinical course and predilection for the extremities. We describe a case of recurrent polymorphous sweat gland carcinoma in a 56-year-old man who presented with ...

journal_title：Journal of the American Academy of Dermatology

authors： Ronnen M,Ben-Dor D,Huszar M

更新日期：2002-06-01 00:00:00

abstract：:New and relatively old types of vascular (capillary) proliferations in the skin have been described or better categorized in the last few years. They include reactive angioendotheliomatosis, acroangiodermatitis (pseudo-Kaposi sarcoma), diffuse dermal angiomatosis, intravascular histocytosis, glomeruloid angioendotheli...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2003-11-01 00:00:00

abstract：:The case of a male diabetic patient with recurrent bullous lesions restricted to the hands is reported. Areas of spongiosis in the epidermis, as well as subepidermal blister formation, were observed in repeated biopsies. On electron microscopy, separation was seen at the level of the lamina lucida. No immunopathology ...

journal_title：Journal of the American Academy of Dermatology

authors： Toonstra J

更新日期：1985-11-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Warren R. Heymann, MD, are provided after each discussion as a topic summary and are provided here as a special service t...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2008-08-01 00:00:00

abstract：:We are reporting seven cases of Mibelli's porokeratosis of the face. Facial involvement of porokeratosis is rare, and in this location the lesions are not clinically recognized. ...

journal_title：Journal of the American Academy of Dermatology

authors： Mehregan AH,Khalili H,Fazel Z

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:BRAF mutations occur in some melanomas. We hypothesized that BRAF mutation rates may differ in melanomas found in Asian compared to white populations. OBJECTIVE:We performed a metaanalysis of BRAF mutations and their associations with the clinicopathologic characteristics of primary melanoma (PM), with a su...

journal_title：Journal of the American Academy of Dermatology

authors： Kim SY,Kim SN,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2015-06-01 00:00:00

abstract：:Costs for dermatitis can be evaluated against the costs and potential benefits of patch testing on the basis of data available from several sources. Consideration of cost for an individual patient suggests that costs become neutral and benefits become positive if the dermatitis is persistent and multiple physician vis...

journal_title：Journal of the American Academy of Dermatology

authors： Rietschel RL

更新日期：1989-10-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：:Squamous cell carcinoma on sun-damaged skin is a malignant neoplasm that evolves from its inception as squamous cell carcinoma in situ, which is commonly referred to as an actinic keratosis. In this study, we reviewed 1011 squamous cell carcinomas on sun-damaged skin and found that nearly 100% of these lesions contain...

journal_title：Journal of the American Academy of Dermatology

authors： Guenthner ST,Hurwitz RM,Buckel LJ,Gray HR

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:The International Dermatology Outcome Measures established a set of core domains to be measured in all psoriasis trials. This set requires that symptoms of psoriatic arthritis (PsA) be measured in all psoriasis studies. OBJECTIVE:To identify the approach to PsA screening and the most appropriate outcome mea...

journal_title：Journal of the American Academy of Dermatology

authors： Perez-Chada LM,Gottlieb AB,Cohen J,Mease P,Duffin KC,Garg A,Latella J,Armstrong AW,Ogdie A,Merola JF

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:While progress has been made in defining the clinical and histopathologic features of high-risk cutaneous squamous cell carcinoma (HRcSCC), optimal staging guidelines remain elusive. OBJECTIVE:We seek to guide clinical practice regarding nodal staging options for patients with HRcSCC via review of evolving ...

journal_title：Journal of the American Academy of Dermatology

authors： Fox M,Brown M,Golda N,Goldberg D,Miller C,Pugliano-Mauro M,Schmults C,Shin T,Stasko T,Xu YG,Nehal K,High Risk Squamous Cell Carcinoma Workgroup.,Dermatologic Surgery Section of the Association of Professors of Dermatology.

更新日期：2019-08-01 00:00:00

abstract：:A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanth...

journal_title：Journal of the American Academy of Dermatology

authors： Chung HG,Chung YL,Kang JM,Yang WI,Suh CO,Hahn JS,Leea MG

更新日期：2003-02-01 00:00:00