Primary idiopathic cutaneous pustular vasculitis.

abstract：:Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

journal_title：Journal of the American Academy of Dermatology

authors： Wester RC,Bucks DA,Maibach HI

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND:Current treatments for vitiligo, a common pigmentary disorder affecting around 1% of the world's population, are largely unsatisfactory. OBJECTIVE:We sought to report a Cochrane review of all interventions for the treatment of vitiligo. METHODS:We systematically searched a range of databases for randomized...

journal_title：Journal of the American Academy of Dermatology

authors： Whitton ME,Ashcroft DM,González U

更新日期：2008-10-01 00:00:00

abstract：:Diagnosis and classification of cutaneous lymphoid infiltrates are often hampered by lack of frozen tissue to allow detailed immunophenotyping. Therefore antibodies that recognize antigens resistant to routine tissue processing would be of value. In this study we present a detailed analysis of two such antibodies agai...

journal_title：Journal of the American Academy of Dermatology

authors： Sterry W,Hauschild A

更新日期：1989-07-01 00:00:00

abstract：:Hyperkeratosis of the nipple and areola is a rare condition. We report two cases of hyperkeratosis of the nipple and areola occurring in men with no underlying endocrinopathy or synthetic estrogenic drug therapy. Both patients demonstrated prompt resolution of the hyperkeratosis of the nipples with a keratolytic gel. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhlman DS,Hodge SJ,Owen LG

更新日期：1985-10-01 00:00:00

abstract：:Pruritic folliculitis of pregnancy is a rare pregnancy dermatosis that clears spontaneously in the postpartum period. We describe a patient with characteristic clinical and histopathologic features of this dermatosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kroumpouzos G,Cohen LM

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:The evidence of hairs grouped into well-defined follicular units has given a new vision of hair anatomy and pathology. The sebaceous glands and the arrector pili muscle, as part of the pilosebaceous unit, should be viewed as important parts of this organized follicular unit structure. OBJECTIVE:This study w...

journal_title：Journal of the American Academy of Dermatology

authors： Poblet E,Jiménez F,Ortega F

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...

journal_title：Journal of the American Academy of Dermatology

authors： Boyd AS,Stasko TS,Tang YW

更新日期：2011-01-01 00:00:00

abstract：:We report the excellent therapeutic response obtained with amikacin alone and in combination with trimethoprim-sulfamethoxazole in the treatment of 15 patients with actinomycotic mycetoma who had a poor response to the traditional pharmacologic agents and/or in whom important organs such as lungs, spinal cord, and bon...

journal_title：Journal of the American Academy of Dermatology

authors： Welsh O,Sauceda E,Gonzalez J,Ocampo J

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with psoriasis have been reported. OBJECTIVES:To assess the prevalence and incidence of PsA in patients with psoriasis. METHODS:Two authors independently searched 3 databases for studies reporting on the prevalence or incidence of P...

journal_title：Journal of the American Academy of Dermatology

authors： Alinaghi F,Calov M,Kristensen LE,Gladman DD,Coates LC,Jullien D,Gottlieb AB,Gisondi P,Wu JJ,Thyssen JP,Egeberg A

更新日期：2019-01-01 00:00:00

abstract：:A 9-year-old girl with systemic lupus erythematosus developed bullous eruption. Histopathologic examination showed subepidermal blistering and immunoglobulins (IgG, IgM, IgA) and complement components (C1q, C3) deposited linearly at the basement membrane zone. IgG in this patient's serum bound to the dermal side of 1 ...

journal_title：Journal of the American Academy of Dermatology

authors： Shirahama S,Furukawa F,Yagi H,Tanaka T,Hashimoto T,Takigawa M

更新日期：1998-05-01 00:00:00

abstract：:Cytokines are glycoproteins produced by many different cells. Via binding to specific receptors on target cells they regulate the activation, differentiation, and proliferation of immune and nonimmune cells. After injury keratinocytes synthesize and release cytokines such as interleukins, colony stimulating factors, a...

journal_title：Journal of the American Academy of Dermatology

authors： Luger TA,Schwarz T

更新日期：1991-06-01 00:00:00

abstract：:A systematic, uniform evaluation of 102 patients with, or at risk for, neurofibromatosis has shown that café au lait spots (CLS), even in large numbers, may not be sufficient to diagnose this disorder, and that several other dermatologic features may provide clues to its pathogenesis. These features include pruritus a...

journal_title：Journal of the American Academy of Dermatology

authors： Riccardi VM

更新日期：1980-08-01 00:00:00

abstract：:A new, quantitative modification of the vasoconstrictor assay was used to measure bioavailability of generic topical corticosteroid products in two categories: betamethasone valerate 0.1% cream and triamcinolone 0.1% cream. Betamethasone valerate products could be separated into two distinct categories, and triamcinol...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson DB,Thompson C,McCormack JR,Guin JD

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipot...

journal_title：Journal of the American Academy of Dermatology

authors： Papp KA,Guenther L,Boyden B,Larsen FG,Harvima RJ,Guilhou JJ,Kaufmann R,Rogers S,van de Kerkhof PC,Hanssen LI,Tegner E,Burg G,Talbot D,Chu A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

journal_title：Journal of the American Academy of Dermatology

authors： Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The dysplastic melanocytic nevus (DMN) is a putative precursor for malignant melanoma in persons with a family history of melanoma and multiple large atypical moles. Furthermore, the concept that DMN confers increased risk for melanoma has been extended to those without a family history of melanoma. Some inv...

journal_title：Journal of the American Academy of Dermatology

authors： Roush GC,Dubin N,Barnhill RL

更新日期：1993-10-01 00:00:00

abstract：:The association of palmoplantar hyperkeratosis and mycosis fungoides (MF) has been described less frequently in the dermatologic literature. We present a patient with MF who developed hyperkeratosis of the palms and soles. Histologic examination of a specimen from the left palm showed microscopic changes of MF. ...

journal_title：Journal of the American Academy of Dermatology

authors： Aram H,Zeidenbaum M

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:A radiofrequency-controlled electrosurgical device (ESD) has been adapted for skin peeling. A high-voltage, low-amperage current converts an irrigant into an ionized vapor, causing molecular dissociation and superficial damage in adjacent tissue. OBJECTIVE:We compared the clinical and histologic effects of ...

journal_title：Journal of the American Academy of Dermatology

authors： Acland KM,Calonje E,Seed PT,Stat C,Barlow RJ

更新日期：2001-03-01 00:00:00

abstract：:The occurrence of Kaposi's sarcoma in young homosexual men is a recently reported condition. The same individuals are at risk for the development of Pneumocystis carinii pneumonia and other unusual infections. These associations suggest these persons are somehow immunocompromised. Evidence of current or prior cytomega...

journal_title：Journal of the American Academy of Dermatology

authors： Rasmussen EO,Cooper KD,Kang K,White CR Jr,Regan DH,Hanifin JM

更新日期：1982-05-01 00:00:00

abstract：:It is often stated that persons of Celtic origin have an increased risk of skin cancer, but the evidence for this is almost exclusively anecdotal. We believe that the possibility of the Celts being at greater risk of skin cancer has important implications with regard to management in particular and in assisting our un...

journal_title：Journal of the American Academy of Dermatology

authors： Long CC,Marks R

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Overexpression of adhesion molecules in tissues of human neoplasms, including malignant melanoma, has been reported to be clinically relevant, but the predictive value of circulating adhesion molecules for clinical outcome and life expectancy in patients with primary malignant melanoma (PMM) and metastases o...

journal_title：Journal of the American Academy of Dermatology

authors： Schaider H,Rech-Weichselbraun I,Richtig E,Seidl H,Soyer HP,Smolle J,Kerl H

更新日期：1997-02-01 00:00:00

abstract：:Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The precise cause of melasma remains unknown; however, there are many possible contributing factors. Because of its dermal component and tendency to relapse, melasma is...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Gover MD,Nouri K,Taylor S

更新日期：2006-12-01 00:00:00

abstract：:The fixed cutaneous type of sporotrichosis is difficult to diagnose because clinical lesions are variable in appearance and the cells of Sporothrix schenckii are usually scarce in skin biopsy specimens. We have described two patients with lesions of fixed cutaneous sporotrichosis that resembled other inflammatory skin...

journal_title：Journal of the American Academy of Dermatology

authors： Bickley LK,Berman IJ,Hood AF

更新日期：1985-06-01 00:00:00

abstract：:The clinical, electron microscopic, and freeze-fracture features of the skin of a harlequin fetus are described. Ultrastructural findings included large, concentric lamellar bodies, focal absence of intercellular stratum corneum lipid, and an increase in the size of desmosomes and the number of tight junctions. Althou...

journal_title：Journal of the American Academy of Dermatology

authors： Fleck RM,Barnadas M,Schulz WW,Roberts LJ,Freeman RG

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Brachioradial pruritus (BRP) is a localized pruritus of the dorsolateral aspect of the arm. BRP is an enigmatic condition with a controversial cause; some authors consider BRP to be a photodermatosis whereas other authors attribute BRP to compression of cervical nerve roots. OBJECTIVE:We sought to investiga...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen AD,Masalha R,Medvedovsky E,Vardy DA

更新日期：2003-06-01 00:00:00

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Severe atopic dermatitis (AD) is increasingly treated with systemic immuno-modulatory drugs yet their safety is unclear. OBJECTIVE:We evaluated the comparative risk of serious bacterial and opportunistic infections among users of systemic immuno-modulatory medications in patients with severe AD in routine c...

journal_title：Journal of the American Academy of Dermatology

authors： Schneeweiss MC,Perez-Chada L,Merola JF

更新日期：2019-05-31 00:00:00

abstract：:A syndrome of congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth was observed in four siblings (three women and one man). The pedigree is suggestive of either an autosomal recessive mode of inheritance or the inheritance of a (small) chromosomal translocation. This combinatio...

journal_title：Journal of the American Academy of Dermatology

authors： Steijlen PM,Neumann HA,der Kinderen DJ,Smeets DF,van der Kerkhof PC,Happle R

更新日期：1994-05-01 00:00:00

abstract：:Galli-Galli disease is an inherited disease characterized by slowly progressive and disfiguring reticulate hyperpigmentation of the flexures, clinically and histopathologically diagnostic for Dowling-Degos disease, but also associated with suprabasal, nondyskeratotic acantholysis. A few patients exhibiting these featu...

journal_title：Journal of the American Academy of Dermatology

authors： Braun-Falco M,Volgger W,Borelli S,Ring J,Disch R

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Facial erythema is a clinical hallmark of rosacea and often causes social and psychological distress. Although facial erythema assessments are a common endpoint in rosacea clinical trials, their reliability has not been evaluated. OBJECTIVE:The objective of this study was to evaluate the inter- and intrarat...

journal_title：Journal of the American Academy of Dermatology

authors： Tan J,Liu H,Leyden JJ,Leoni MJ

更新日期：2014-10-01 00:00:00