Therapeutic use of cytokines in dermatology.

abstract：:The term "the contact urticaria syndrome," proposed in 1975, has been generally accepted and led to proliferation of new examples. This paper summarizes this clinical material and presents a diagnostic and pathogenetic evaluation method. The risks (and minimization, thereof) of systemic skin test-induced reactions are...

journal_title：Journal of the American Academy of Dermatology

authors： von Krogh G,Maibach HI

更新日期：1981-09-01 00:00:00

abstract：:Five patients with the yellow nail syndrome triad are described; all five had yellow nails, primary lymphedema, and respiratory tract involvement. Four of the patients noted the onset of the syndrome after an episode of pneumonia. Four patients had a chronic productive cough, two had bronchiectasis, two had chronic si...

journal_title：Journal of the American Academy of Dermatology

authors： Venencie PY,Dicken CH

更新日期：1984-02-01 00:00:00

abstract：:A tense yellow vesicle was noted on the back parietal scalp of a female newborn. This proved to be a bullous variant of aplasia cutis congenita. Only 16 cases of this apparently rare disorder have been previously reported. Histologic evaluation of such lesions reveals a distinct pattern containing fibrovascular stroma...

journal_title：Journal of the American Academy of Dermatology

authors： Colon-Fontanez F,Fallon Friedlander S,Newbury R,Eichenfield LF

更新日期：2003-05-01 00:00:00

abstract：:Cultured epidermal sheets were examined before and at various times after grafting on skin ulcer beds. Before grafting, the sheet consisted of four to five layers of keratinocytes with incomplete differentiation. Ten days after grafting, graft recipient sites showed compact hyperkeratosis, a normal-appearing epidermis...

journal_title：Journal of the American Academy of Dermatology

authors： Phillips TJ,Bhawan J,Leigh IM,Baum HJ,Gilchrest BA

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The cause of lichen sclerosus et atrophicus (LSA) is unknown, but on the penis it is associated with chronic occlusion, that is, phimosis. Microscopic changes of LSA were seen unexpectedly in two acrochordons. OBJECTIVE:Our purpose was to further characterize this phenomenon. METHODS:A total of 449 acrocho...

journal_title：Journal of the American Academy of Dermatology

authors： Weigand DA

更新日期：1993-05-01 00:00:00

abstract：:Linear IgA bullous dermatosis (LABD) is an autoimmune blistering skin disease characterized by circulating IgA antibodies binding the basement membrane zone. In most cases the origin is not clear, but in a minority of cases LABD is drug induced. We describe a patient in whom linear IgA disease developed shortly after ...

journal_title：Journal of the American Academy of Dermatology

authors： König C,Eickert A,Scharfetter-Kochanek K,Krieg T,Hunzelmann N

更新日期：2001-04-01 00:00:00

abstract：:Five patients with cutaneous leishmaniasis are described. Four of these patients acquired leishmaniasis in Texas. Four cases represent acute cutaneous leishmaniasis, and one case probably represents chronic cutaneous leishmaniasis. The classification and treatment of cutaneous leishmaniasis are reviewed. One patient i...

journal_title：Journal of the American Academy of Dermatology

authors： Nelson DA,Gustafson TL,Spielvogel RL

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

journal_title：Journal of the American Academy of Dermatology

authors： Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

更新日期：2019-02-01 00:00:00

abstract：:Onychomadesis is defined as spontaneous separation of the nail plate from the nail bed, beginning at its proximal end and resulting in the shedding of the nail. It has been associated with a variety of clinical settings, including systemic illnesses, generalized skin diseases, and drug therapies. There have been a sma...

journal_title：Journal of the American Academy of Dermatology

authors： Mehra A,Murphy RJ,Wilson BB

更新日期：2000-08-01 00:00:00

abstract：:Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...

journal_title：Journal of the American Academy of Dermatology

authors： Chapel TA,Mehregan AH,Reyman TA

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Dermatomyositis affects visible skin and causes disease symptoms that can affect patients' quality of life (QOL). METHODS:In all, 71 patients with dermatomyositis or dermatomyositis sine myositis completed two QOL measures (the Skindex-16 and the Dermatology Life Quality Index) and a visual analog scale for...

journal_title：Journal of the American Academy of Dermatology

authors： Hundley JL,Carroll CL,Lang W,Snively B,Yosipovitch G,Feldman SR,Jorizzo JL

更新日期：2006-02-01 00:00:00

abstract：:The incidence of malignant melanoma is increasing faster than that of any other cancer. It is important to identify subsets of the population at high risk of its development so that they can be observed more closely to identify early melanomas when they are curable. It has been reported worldwide that persons with the...

journal_title：Journal of the American Academy of Dermatology

authors： Slade J,Marghoob AA,Salopek TG,Rigel DS,Kopf AW,Bart RS

更新日期：1995-03-01 00:00:00

abstract：:Two babies were found to have large hemangiomas. Histologically there were many islands of compactly packed mesenchymal cells in the deep dermis and subcutaneous tissue. Electron microscopically there was proliferation of immature endothelial cells and pericytes. Characteristic crystalline lamellae were in the endothe...

journal_title：Journal of the American Academy of Dermatology

authors： Kumakiri M,Muramoto F,Tsukinaga I,Yoshida T,Ohura T,Miura Y

更新日期：1983-01-01 00:00:00

abstract：:Soft tissue augmentation is a frequently performed outpatient operation. Products available for soft tissue augmentation vary in chemistry, clinical indications, and toxicity. This review examines safety and efficacy data for collagen implants (Zyderm and Zyplast), gelatin matrix implants (Fibrel), and injectable sili...

journal_title：Journal of the American Academy of Dermatology

authors： Clark DP,Hanke CW,Swanson NA

更新日期：1989-11-01 00:00:00

abstract：:Cicatricial pemphigoid is a chronic, presumed autoimmune, blistering disease of the mucous membranes and occasionally of the skin. The characteristic feature is scarring at the sites of healing. We report the use of thalidomide as a therapeutic agent to control previously resistant disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Duong DJ,Moxley RT 3rd,Kellman RM,Pincus SH,Gaspari AA

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

journal_title：Journal of the American Academy of Dermatology

authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

更新日期：2009-05-01 00:00:00

abstract：:Urticaria is one of the more common skin conditions seen by physicians. Physical agents are an important cause of urticaria, with pressure or shearing forces being the most common. Dermographism is due to a combination of pressure and shearing forces and is present in a large number of healthy individuals. The purpose...

journal_title：Journal of the American Academy of Dermatology

authors： Wong RC,Fairley JA,Ellis CN

更新日期：1984-10-01 00:00:00

abstract：:In a pilot study the therapeutic effect and side effect profile of low-dose interferon alfa-2b in combination with a retinoid for the treatment of cutaneous T cell lymphoma were evaluated. Seven patients (four women, three men) with histologically confirmed cutaneous T cell lymphoma were included. Four patients had re...

journal_title：Journal of the American Academy of Dermatology

authors： Knobler RM,Trautinger F,Radaszkiewicz T,Kokoschka EM,Micksche M

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Few effective treatments are available for male pattern hair loss (MPHL) or, especially, for female pattern hair loss (FPHL). Recently, cell-based therapies using autologous or allogeneic cells have been used clinically. OBJECTIVE:We examined the safety and efficacy of autologous cell-based therapy using de...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuboi R,Niiyama S,Irisawa R,Harada K,Nakazawa Y,Kishimoto J

更新日期：2020-07-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:The use of the various forms of phototherapy remains an essential treatment option for psoriasis vulgaris. Expertise concerning the mechanisms involved with the actions of therapeutic ultraviolet light and the proper delivery of office-based treatments resides within the specialty of dermatology. New therapies for the...

journal_title：Journal of the American Academy of Dermatology

authors： Zanolli M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. OBJECTIVE:We sought to determine the reliability and validity of the MASI. METHODS:After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once d...

journal_title：Journal of the American Academy of Dermatology

authors： Pandya AG,Hynan LS,Bhore R,Riley FC,Guevara IL,Grimes P,Nordlund JJ,Rendon M,Taylor S,Gottschalk RW,Agim NG,Ortonne JP

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. STUDY PATIENTS:The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. RESULTS:Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Boztepe G,Akinci H,Sahin S,Karaduman A,Evans SE,Erkin G,Atakan N,Akan T,Kölemen F

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Risk of cutaneous melanoma is increased among organ transplant recipients (OTRs) but outcome has rarely been evaluated. OBJECTIVE:We sought to assess melanoma characteristics and prognosis among OTRs versus the general population. METHODS:Using Swedish health care registers, we identified melanomas in OTRs...

journal_title：Journal of the American Academy of Dermatology

authors： Krynitz B,Rozell BL,Lyth J,Smedby KE,Lindelöf B

更新日期：2015-07-01 00:00:00

abstract：:Acrocyanosis is an uncommon condition characterized by symmetric coolness and violaceous discoloration of the hands and feet. The nose, ears, lips, and nipples are also often affected. The disease is temperature dependent and generally worsens with cold exposure. Acrocyanosis is often secondary to a variety of underly...

journal_title：Journal of the American Academy of Dermatology

authors： Nousari HC,Kimyai-Asadi A,Anhalt GJ

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Despite improvements in melanoma mortality, disparities in melanoma survival persist. We evaluated possible sociodemographic and health care-based predictors of differences in melanoma survival in the United States by using the melanoma mortality-to-incidence ratio (MIR). METHODS:State-based MIRs were calcu...

journal_title：Journal of the American Academy of Dermatology

authors： Hopkins ZH,Moreno C,Carlisle R,Secrest AM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:There is growing evidence that Mohs micrographic surgery (MMS) is the treatment of choice for dermatofibrosarcoma protuberans (DFSP). OBJECTIVE:This study retrospectively compared the recurrence rates of DFSP after MMS with those after wide surgical excision; results at the Mayo Clinic and in the world lite...

journal_title：Journal of the American Academy of Dermatology

authors： Gloster HM Jr,Harris KR,Roenigk RK

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipot...

journal_title：Journal of the American Academy of Dermatology

authors： Papp KA,Guenther L,Boyden B,Larsen FG,Harvima RJ,Guilhou JJ,Kaufmann R,Rogers S,van de Kerkhof PC,Hanssen LI,Tegner E,Burg G,Talbot D,Chu A

更新日期：2003-01-01 00:00:00

abstract：:Ochronosis is an uncommon condition characterized by yellow-brown pigment deposits in the dermis. It occurs in exogenous and endogenous forms. We report a case of exogenous ochronosis in a Hispanic woman and discuss the different forms of this condition. We treated the lesions with Q-switched ruby laser. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kramer KE,Lopez A,Stefanato CM,Phillips TJ

更新日期：2000-05-01 00:00:00