Linear IgA bullous dermatosis induced by atorvastatin.

Abstract:

:Linear IgA bullous dermatosis (LABD) is an autoimmune blistering skin disease characterized by circulating IgA antibodies binding the basement membrane zone. In most cases the origin is not clear, but in a minority of cases LABD is drug induced. We describe a patient in whom linear IgA disease developed shortly after beginning therapy with atorvastatin. In Western blotting analysis we detected IgA and IgG class antibodies targeting a 97-kd protein. To our knowledge this is the first reported case of atorvastatin-induced LABD.

journal_name

J Am Acad Dermatol

authors

König C,Eickert A,Scharfetter-Kochanek K,Krieg T,Hunzelmann N

doi

10.1067/mjd.2001.113462

subject

Has Abstract

pub_date

2001-04-01 00:00:00

pages

689-92

issue

4

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(01)73526-8

journal_volume

44

pub_type

杂志文章
  • Androgenetic alopecia treated with topical minoxidil.

    abstract::A randomized double-blind trial of topical minoxidil was carried out during a 12-month period in 56 patients with male pattern baldness. Subjects were randomly assigned to treatment with either 2% minoxidil solution, 3% minoxidil solution, or placebo. The placebo group was switched to 3% minoxidil after the first 4 mo...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0190-9622(87)70085-1

    authors: De Villez RL

    更新日期:1987-03-01 00:00:00

  • Clinical aspects of cutaneous leishmaniasis acquired in Texas.

    abstract::Five patients with cutaneous leishmaniasis are described. Four of these patients acquired leishmaniasis in Texas. Four cases represent acute cutaneous leishmaniasis, and one case probably represents chronic cutaneous leishmaniasis. The classification and treatment of cutaneous leishmaniasis are reviewed. One patient i...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70125-9

    authors: Nelson DA,Gustafson TL,Spielvogel RL

    更新日期:1985-06-01 00:00:00

  • Interclinician agreement on the recognition of selected gross morphologic features of pigmented lesions. Studies of melanocytic nevi V.

    abstract:BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(92)70023-9

    authors: Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

    更新日期:1992-02-01 00:00:00

  • Childhood stye and adult rosacea.

    abstract:BACKGROUND:Little is known about how individuals with a predisposition for rosacea appear in childhood. This retrospective, matched control, longitudinal study examined the relationship between childhood stye and adult rosacea. METHODS:The records of the Rochester Epidemiology Project were examined to identify patient...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2006.03.023

    authors: Bamford JT,Gessert CE,Renier CM,Jackson MM,Laabs SB,Dahl MV,Rogers RS 3rd

    更新日期:2006-12-01 00:00:00

  • The skin as an immunologic organ. A tribute to Marion B. Sulzberger.

    abstract::The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70195-8

    authors: Katz SI

    更新日期:1985-09-01 00:00:00

  • Immunohistochemical detection of proliferation and differentiation in discoid lupus erythematosus.

    abstract::Discoid lupus erythematosus lesions show hyperkeratosis and atrophy, which may reflect abnormal epidermal proliferation, differentiation, or both. In this investigation, markers for epidermal proliferation, differentiation and inflammation were studied in cutaneous lesions of discoid lupus erythematosus. Frozen sectio...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(91)70303-j

    authors: de Jong EM,van Erp PE,Ruiter DJ,van de Kerkhof PC

    更新日期:1991-12-01 00:00:00

  • Punch biopsy of melanoma.

    abstract::A 46-year-old albino woman is described with a melanoma on the leg from which a punch biopsy specimen was inadvertently taken. In the reexcision specimen, two biopsy wounds were recognized that were filled with tumor. The initial level III lesion had to be subsequently reported as a deep level IV amelanotic melanoma w...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70238-1

    authors: van der Esch EP,Rampen FH

    更新日期:1985-11-01 00:00:00

  • Nasal reconstruction utilizing a muscle hinge flap with overlying full-thickness skin graft.

    abstract:BACKGROUND:Deep nasal defects of the dorsum, sidewall, and ala can be challenging to repair. OBJECTIVE:The article describes our experience with a muscle hinge transposition flap with overlying local full-thickness skin grafting for repair of deep nasal defects in a single-stage procedure. METHODS:A muscle hinge tran...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2000.108374

    authors: Fader DJ,Wang TS,Johnson TM

    更新日期:2000-11-01 00:00:00

  • Alleged isotretinoin-associated inflammatory bowel disease: disproportionate reporting by attorneys to the Food and Drug Administration Adverse Event Reporting System.

    abstract:BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2013.04.031

    authors: Stobaugh DJ,Deepak P,Ehrenpreis ED

    更新日期:2013-09-01 00:00:00

  • Familial aquagenic urticaria associated with familial lactose intolerance.

    abstract::Aquagenic urticaria is a rare disorder characterized by the occurrence of pruritus and wheals after temporary contact with water. The familial occurrence of aquagenic urticaria over 3 generations is reported here in association with familial lactose intolerance, a condition in which the enzyme lactase encoded on chrom...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2002.124599

    authors: Treudler R,Tebbe B,Steinhoff M,Orfanos CE

    更新日期:2002-10-01 00:00:00

  • Multiple vascular fibromas and myxoid fibromas of the fingers. A histologic and ultrastructural study.

    abstract::A father and his son were seen because of multiple wartlike lesions on their fingers and palms. On histologic examination, these lesions showed changes compatible with vascular fibromas, myxoid fibromas, and, in a few instances, verruca vulgaris. We are not aware of reports of similar cases in the dermatologic literat...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(80)80367-7

    authors: Coskey RJ,Mehregan AH,Lupulescu AP

    更新日期:1980-05-01 00:00:00

  • The use of topical diphenylcyclopropenone for the treatment of extensive alopecia areata.

    abstract:BACKGROUND:Highly variable results of topical diphenylcyclopropenone (DPCP) in the treatment of alopecia areata have been reported so far. OBJECTIVE:The purposes of our study were to evaluate the efficacy and tolerability of DPCP in the treatment of chronic, extensive alopecia areata and to assess the long-term overal...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1067/mjd.2001.109309

    authors: Cotellessa C,Peris K,Caracciolo E,Mordenti C,Chimenti S

    更新日期:2001-01-01 00:00:00

  • Nodal staging of high-risk cutaneous squamous cell carcinoma.

    abstract:BACKGROUND:While progress has been made in defining the clinical and histopathologic features of high-risk cutaneous squamous cell carcinoma (HRcSCC), optimal staging guidelines remain elusive. OBJECTIVE:We seek to guide clinical practice regarding nodal staging options for patients with HRcSCC via review of evolving ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2018.09.006

    authors: Fox M,Brown M,Golda N,Goldberg D,Miller C,Pugliano-Mauro M,Schmults C,Shin T,Stasko T,Xu YG,Nehal K,High Risk Squamous Cell Carcinoma Workgroup.,Dermatologic Surgery Section of the Association of Professors of Dermatology.

    更新日期:2019-08-01 00:00:00

  • Crystalline lamellae in the endothelial cells of a type of hemangioma characterized by the proliferation of immature endothelial cells and pericytes--angioblastoma (Nakagawa).

    abstract::Two babies were found to have large hemangiomas. Histologically there were many islands of compactly packed mesenchymal cells in the deep dermis and subcutaneous tissue. Electron microscopically there was proliferation of immature endothelial cells and pericytes. Characteristic crystalline lamellae were in the endothe...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(83)70009-5

    authors: Kumakiri M,Muramoto F,Tsukinaga I,Yoshida T,Ohura T,Miura Y

    更新日期:1983-01-01 00:00:00

  • A kindred with congenital vellus hair cysts.

    abstract::Vellus hair cysts were present from birth in two of four siblings and their mother. There has been no tendency for remission. This is the first report of vellus hair cysts appearing at birth, and the second report of a kindred in which there was apparent autosomal dominant inheritance. This disorder appears to represe...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(81)70127-0

    authors: Piepkorn MW,Clark L,Lombardi DL

    更新日期:1981-12-01 00:00:00

  • Langerhans cell histiocytosis and dermatophytosis.

    abstract::Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(93)70191-u

    authors: Pakula AS,Paller AS

    更新日期:1993-08-01 00:00:00

  • The superficial mycoses and the dermatophytes.

    abstract::More than 100,000 species of fungi have been identified worldwide, but only a few dozen are of medical significance. Because of the opportunistic nature of these organisms and the prevalence of immunodeficient conditions, the number of medically important fungi is increasing. Identification of the causative organism i...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(89)70234-6

    authors: Elewski BE,Hazen PG

    更新日期:1989-10-01 00:00:00

  • Potential role of microorganisms in the pathogenesis of rosacea.

    abstract::Rosacea is a skin condition of abnormal inflammation and vascular dysfunction. The active contribution of a microbial agent in the development or progression of rosacea continues to be debated. Research supports the presence of commensal Demodex folliculorum mites at increased density in the skin and associates Helico...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2013.08.006

    authors: Holmes AD

    更新日期:2013-12-01 00:00:00

  • Benign lymphangiomatous papules of the skin associated with ovarian fibroma.

    abstract::Benign lymphangiomatous papules of the skin are considered reactive lymphatic proliferations either caused by disruption of the lymphatic flow or tissue damage produced by operation or radiation therapy. We report a 72-year-old woman with umbilical papules and vesicle-like lesions that led to the diagnosis of a large ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2006.05.056

    authors: Bodet D,Rodríguez-Cano L,Bartralot R,Mollet J,Medina A,Heras C,Bassas P,Huguet P,García-Patos V

    更新日期:2007-02-01 00:00:00

  • Papulosquamous diseases: a review.

    abstract::Papulosquamous diseases are a heterogeneous group of disorders whose etiology primarily is unknown. The nosology of these disorders is based on a descriptive morphology of clinical lesions characterized by scaly papules and plaques. The major entities in this group include psoriasis, parapsoriasis (including pityriasi...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(85)70084-9

    authors: Fox BJ,Odom RB

    更新日期:1985-04-01 00:00:00

  • The role of wide local excision for the treatment of severe hidradenitis suppurativa (Hurley grade III): Retrospective analysis of 74 patients.

    abstract:BACKGROUND:Effective medical treatment for patients with severe hidradenitis suppurativa (HS) is limited. OBJECTIVES:We sought to measure the impact of wide local excision on quality of life in HS Hurley grade III patients and to examine the rate of postoperative complications, disease recurrences, and satisfaction wi...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2017.01.055

    authors: Posch C,Monshi B,Quint T,Vujic I,Lilgenau N,Rappersberger K

    更新日期:2017-07-01 00:00:00

  • Seborrheic keratosis: reflectance confocal microscopy features and correlation with dermoscopy.

    abstract:BACKGROUND:Differentiation between seborrheic keratosis (SK) and skin cancers may be difficult. Reflectance confocal microscopy (RCM) enables noninvasive assessment of skin neoplasms at cellular-level resolution. OBJECTIVE:We sought to describe RCM features of SK and to correlate these RCM findings with dermoscopic st...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2012.12.969

    authors: Ahlgrimm-Siess V,Cao T,Oliviero M,Laimer M,Hofmann-Wellenhof R,Rabinovitz HS,Scope A

    更新日期:2013-07-01 00:00:00

  • Apoeccrine sweat duct obstruction as a cause for Fox-Fordyce disease.

    abstract::The pathogenesis of Fox-Fordyce disease has been reported to be hyperkeratosis and obstruction of the upper hair follicle, where the duct of the apocrine sweat gland opens. We report a case of Fox-Fordyce disease with full clinical manifestation. It appeared to be caused by the obstruction of intraepidermal apoeccrine...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2003.93

    authors: Kamada A,Saga K,Jimbow K

    更新日期:2003-03-01 00:00:00

  • The pharmacology of methotrexate.

    abstract::Methotrexate is a useful antimetabolite for the treatment of both benign and malignant proliferative disorders. When the pharmacokinetics and potential toxicity of this drug are understood, treatment regimens can be tailored to the underlying kinetics of the target population. With the appropriate knowledge of the imp...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(91)70199-c

    authors: Olsen EA

    更新日期:1991-08-01 00:00:00

  • In vivo percutaneous absorption of hydrocortisone in psoriatic patients and normal volunteers.

    abstract::Our objective was to determine the percutaneous absorption of hydrocortisone in psoriatic skin. [14C]-Hydrocortisone formulated as a 0.5% cream was applied to sharply defined erythematous plaques with silvery scales on the dorsal forearm of four hospitalized psoriatic patients. An average 2.32 +/- 1.4 (SD) percent of ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(83)70072-1

    authors: Wester RC,Bucks DA,Maibach HI

    更新日期:1983-05-01 00:00:00

  • Hutchinson's sign: a reappraisal.

    abstract::Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(96)90839-7

    authors: Baran R,Kechijian P

    更新日期:1996-01-01 00:00:00

  • Cyclosporine treatment for Stevens-Johnson syndrome/toxic epidermal necrolysis: Retrospective analysis of a cohort treated in a specialized referral center.

    abstract:BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2016.07.048

    authors: Lee HY,Fook-Chong S,Koh HY,Thirumoorthy T,Pang SM

    更新日期:2017-01-01 00:00:00

  • The Localized Scleroderma Cutaneous Assessment Tool: responsiveness to change in a pediatric clinical population.

    abstract:BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2013.02.007

    authors: Kelsey CE,Torok KS

    更新日期:2013-08-01 00:00:00

  • Aggressive cutaneous T-cell lymphomas after TNFalpha blockade.

    abstract::Pharmacologic blockade of TNFalpha has been a highly effective approach to treating several immunologically mediated diseases, including rheumatoid arthritis, Crohn's disease, and psoriatic arthritis. 1,2,3 Both etanercept, the recombinant extracellular domain of the tumor necrosis factor receptor 2 (TNFR2), and infli...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2004.03.047

    authors: Adams AE,Zwicker J,Curiel C,Kadin ME,Falchuk KR,Drews R,Kupper TS

    更新日期:2004-10-01 00:00:00

  • Role of imaging in low-grade cutaneous B-cell lymphoma presenting in the skin.

    abstract:BACKGROUND:Whole-body imaging is the current standard of care for staging all patients presenting with skin lesions of B-cell lymphomas (BCLs), regardless of skin disease extent; however, supporting data are lacking. OBJECTIVE:To determine the clinical utility of imaging in the detection of systemic involvement in low...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2019.01.037

    authors: Kheterpal MK,Dai J,Geller S,Pulitzer M,Ni A,Myskowski PL,Moskowitz A,Kim J,Hong EK,Fong S,Hoppe RT,Kim YH,Horwitz SM

    更新日期:2019-10-01 00:00:00