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In search of an optimum dose escalation for narrowband UVB phototherapy: is it time to quit 20% increments?

Abstract：

OBJECTIVES:Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. STUDY PATIENTS:The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. RESULTS:Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalations, whereas response rates and time to response did not significantly differ. LIMITATIONS:The study was limited by its retrospective nature. CONCLUSION:A 5% or 10% incremental regimen may have similar therapeutic efficacy.

journal_name

J Am Acad Dermatol

journal_title

Journal of the American Academy of Dermatology

authors

Boztepe G,Akinci H,Sahin S,Karaduman A,Evans SE,Erkin G,Atakan N,Akan T,Kölemen F

doi

10.1016/j.jaad.2006.04.019

subject

Has Abstract

pub_date

2006-08-01 00:00:00

pages

269-71

issue

2

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(06)01196-0

journal_volume

55

pub_type

杂志文章

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