Congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth in four siblings: a new syndrome?

abstract：:Cutaneous metastases present themselves in a variety of clinical patterns and tend to be manifested as indurated papules/nodules/tumors. Some of those clinical expressions are unique for certain types of metastases. This report describes an entirely different phenomenon of clinically incognito cutaneous metastases tha...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,DiLeonardo M,Gibbons G

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Whole-body imaging is the current standard of care for staging all patients presenting with skin lesions of B-cell lymphomas (BCLs), regardless of skin disease extent; however, supporting data are lacking. OBJECTIVE:To determine the clinical utility of imaging in the detection of systemic involvement in low...

journal_title：Journal of the American Academy of Dermatology

authors： Kheterpal MK,Dai J,Geller S,Pulitzer M,Ni A,Myskowski PL,Moskowitz A,Kim J,Hong EK,Fong S,Hoppe RT,Kim YH,Horwitz SM

更新日期：2019-10-01 00:00:00

abstract：:We report a case of amelanotic melanoma that was clinically and dermoscopically featureless; it was repeatedly missed during examination at a pigmented lesion clinic. Dermoscopy evidenced a peculiar vascular pattern, and only the adoption of a specific diagnostic algorithm including the atypical vascular pattern among...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,Massi D,de Giorgi V,Giannotti B

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Pemphigus vulgaris (PV) shows autoimmune reaction against desmoglein 3 (Dsg3), whereas paraneoplastic pemphigus (PNP) shows autoimmune reaction against Dsg3 as well as numerous members of the plakin family. It has been demonstrated that in PV, dominant epitopes reside in N-terminal adhesive regions of Dsg3 a...

journal_title：Journal of the American Academy of Dermatology

authors： Futei Y,Amagai M,Hashimoto T,Nishikawa T

更新日期：2003-12-01 00:00:00

abstract：:A case of phaeohyphomycosis caused by Phialophora richardsiae is presented. The patient was a 30-year-old man with end stage malignant lymphoma. A subcutaneous abscess that developed on the dorsum of the right foot was removed surgically but immediately recurred. The causative mold was isolated from the pus in the les...

journal_title：Journal of the American Academy of Dermatology

authors： Ikai K,Tomono H,Watanabe S

更新日期：1988-09-01 00:00:00

abstract：:Meibomian carcinoma is rare but carries a grave prognosis. The lesion may be easily mistaken for inflammatory condition. Therefore, any nodular or recurrent lesion on the eyelid of an elderly person should be examined histologically. A case is presented in which the tumor was successfully treated by the Mohs microscop...

journal_title：Journal of the American Academy of Dermatology

authors： Dixon RS,Mikhail GR,Slater HC

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND:Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge. METHODS:We report a case using an enzyme-linked immunosorbent assay (ELISA) test. RESULTS:A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identif...

journal_title：Journal of the American Academy of Dermatology

authors： Stoecker WV,Green JA,Gomez HF

更新日期：2006-11-01 00:00:00

abstract：:Eosinophilic spongiosis has a distinctive but not diagnostic histologic pattern of the epidermis. This pattern may be seen in a wide variety of clinical disorders. We have observed it most commonly in bullous pemphigoid, particularly the urticarial stage. In most biopsy specimens that show eosinophilic spongiosis, add...

journal_title：Journal of the American Academy of Dermatology

authors： Crotty C,Pittelkow M,Muller SA

更新日期：1983-03-01 00:00:00

abstract：:In this third and last part of our review of cutaneous vascular proliferations we include malignant vascular neoplasms and a group of heterogeneous cutaneous neoplasms characterized by a significant vascular component. We also review some disorders that, in our opinion, have been erroneously considered as vascular neo...

journal_title：Journal of the American Academy of Dermatology

authors： Requena L,Sangueza OP

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature. OBJECTIVE:To provide up-to-date information regarding the state of teledermatology programs in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Wu J,Kovarik CL,Goldyne ME,Oh DH,McKoy KC,Shippy AM,Pak HS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Only a few clinical trials have been performed on the treatment of generalized vitiligo in children. Recently, narrow-band UVB therapy has been reported to be an effective and safe therapeutic option in adult patients with vitiligo. OBJECTIVE:We studied the efficacy and safety of UVB (311 nm) therapy in chi...

journal_title：Journal of the American Academy of Dermatology

authors： Njoo MD,Bos JD,Westerhof W

更新日期：2000-02-01 00:00:00

abstract：:Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that present with unique clinical features but are unified by the presence of a sterile, predominantly neutrophilic infiltrate on histopathology. The morphology of cutaneous lesions associated with these disorders is heterogeneous, which ...

journal_title：Journal of the American Academy of Dermatology

authors： Nelson CA,Stephen S,Ashchyan HJ,James WD,Micheletti RG,Rosenbach M

更新日期：2018-12-01 00:00:00

abstract：:In this randomized, double-blind, phase III trial, patients with psoriasis received etanercept for 24 weeks or placebo for 12 weeks followed by etanercept for 12 weeks. At week 12, improvement in Dermatology Life Quality Index was 47% to 61% with etanercept compared with 11% with placebo (P < .0001). Etanercept rapidl...

journal_title：Journal of the American Academy of Dermatology

authors： Feldman SR,Kimball AB,Krueger GG,Woolley JM,Lalla D,Jahreis A

更新日期：2005-11-01 00:00:00

abstract：:Isotretinoin has demonstrated efficacy in a wide range of disorders. The beneficial effects of the drug, however, are limited by its adverse effects on the bone. Children exposed to high doses are at risk for premature epiphyseal closure, while adults on long-term therapy have an increased tendency to develop hypersto...

journal_title：Journal of the American Academy of Dermatology

authors： DiGiovanna JJ

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The International Dermatology Outcome Measures established a set of core domains to be measured in all psoriasis trials. This set requires that symptoms of psoriatic arthritis (PsA) be measured in all psoriasis studies. OBJECTIVE:To identify the approach to PsA screening and the most appropriate outcome mea...

journal_title：Journal of the American Academy of Dermatology

authors： Perez-Chada LM,Gottlieb AB,Cohen J,Mease P,Duffin KC,Garg A,Latella J,Armstrong AW,Ogdie A,Merola JF

更新日期：2020-01-01 00:00:00

abstract：:Incontinentia pigmenti is a rare genodermatosis of unknown etiology. A female infant with features typical of this disease was found to have basophils in early vesicular lesions. Mediators from these cells may be responsible for the accumulation of eosinophils in these lesions. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schmalstieg FC,Jorizzo JL,Tschen J,Subrt P

更新日期：1984-02-01 00:00:00

abstract：:Erythema multiforme and Stevens-Johnson syndrome are both characterized by areas of epithelial necrosis. An important clinical feature that distinguishes the two is the extensive mucosal necrosis in Stevens-Johnson syndrome but not in erythema multiforme. Because significant and serious complications may develop with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weston WL,Morelli JG,Rogers M

更新日期：1997-11-01 00:00:00

abstract：:Dacarbazine (DTIC-Dome) is a widely used chemotherapeutic agent employed in the therapy of malignant melanoma. In this communication, we present two patients who developed photosensitivity skin reactions immediately after its administration. Physicians using dacarbazine should be aware of this side effect and should i...

journal_title：Journal of the American Academy of Dermatology

authors： Yung CW,Winston EM,Lorincz AL

更新日期：1981-05-01 00:00:00

abstract：:A patient who had a plaque on his forehead as the first sign of chronic myelomonocytic leukemia (CMML) is described. Histologic studies, which formerly led to the misdiagnosis of non-Hodgkin's lymphoma, revealed CMML with an unusual phenotype. This represents a rare type of CMML for the following reasons: (1) specific...

journal_title：Journal of the American Academy of Dermatology

authors： Braga D,Manganoni AM,Boccaletti V,Pancera C,Marocolo D,Facchetti F,De Panfilis G

更新日期：1996-11-01 00:00:00

abstract：:Two babies were found to have large hemangiomas. Histologically there were many islands of compactly packed mesenchymal cells in the deep dermis and subcutaneous tissue. Electron microscopically there was proliferation of immature endothelial cells and pericytes. Characteristic crystalline lamellae were in the endothe...

journal_title：Journal of the American Academy of Dermatology

authors： Kumakiri M,Muramoto F,Tsukinaga I,Yoshida T,Ohura T,Miura Y

更新日期：1983-01-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：:A new disorder of the hair follicle is described that leads to increased fragility of the shaft. Light microscopic studies of hair follicles revealed disturbances of keratinization in the shafts that are very likely responsible for the breakage. The most consistent change seen by transmission electron microscopy was i...

journal_title：Journal of the American Academy of Dermatology

authors： Birnbaum PS,Baden HP,Bronstein BR,Nakagawa H,Hori Y

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. OBJECTIVE:We sought to determine the reliability and validity of the MASI. METHODS:After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once d...

journal_title：Journal of the American Academy of Dermatology

authors： Pandya AG,Hynan LS,Bhore R,Riley FC,Guevara IL,Grimes P,Nordlund JJ,Rendon M,Taylor S,Gottschalk RW,Agim NG,Ortonne JP

更新日期：2011-01-01 00:00:00

abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

更新日期：2008-08-01 00:00:00

abstract：:The fixed cutaneous type of sporotrichosis is difficult to diagnose because clinical lesions are variable in appearance and the cells of Sporothrix schenckii are usually scarce in skin biopsy specimens. We have described two patients with lesions of fixed cutaneous sporotrichosis that resembled other inflammatory skin...

journal_title：Journal of the American Academy of Dermatology

authors： Bickley LK,Berman IJ,Hood AF

更新日期：1985-06-01 00:00:00

abstract：:Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification, metastatic calcification, idiopathic calcification, iatrogenic calcification, and calciphylaxis. Dystrophic calcification appears a...

journal_title：Journal of the American Academy of Dermatology

authors： Reiter N,El-Shabrawi L,Leinweber B,Berghold A,Aberer E

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Although hypersensitivity reactions are well characterized for certain medications, vancomycin-associated drug-induced hypersensitivity syndrome (DIHS), or drug reaction with eosinophilia and systemic symptoms (DRESS), has yet to be defined. OBJECTIVE:To better define the clinical phenotype of vancomycin-as...

journal_title：Journal of the American Academy of Dermatology

authors： Madigan LM,Fox LP

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Rosacea is a chronic inflammatory skin disease. Inflammation plays a prominent role in atherosclerosis and its complications. OBJECTIVE:We sought to investigate the associations of rosacea with cardiovascular disease risk factors and cardiovascular diseases from a nationwide population-based database. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Hua TC,Chung PI,Chen YJ,Wu LC,Chen YD,Hwang CY,Chu SY,Chen CC,Lee DD,Chang YT,Liu HN

更新日期：2015-08-01 00:00:00

abstract：:Pustular cutaneous vasculitis results from a heterogeneous group of disorders characterized by pustules on purpuric bases. Although the cause of this group of conditions is diverse, the histopathologic picture of the lesions is the same, showing a Sweet's-like or leukocytoclastic vasculitis. These distinctive lesions ...

journal_title：Journal of the American Academy of Dermatology

authors： McNeely MC,Jorizzo JL,Solomon AR Jr,Schmalstieg FC,Cavallo T

更新日期：1986-05-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00