Occurrence of subacute cutaneous lupus erythematosus after treatment with fluorouracil and capecitabine.

abstract：:The etiology of mycosis fungoides (MF) is uncertain, although infectious agents and other environmental exposures have been implicated. We describe what appears to be the first case in which both a husband and his wife were diagnosed with large-cell transformation of MF. After 10 years of having stage I MF, the wife d...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt AN,Robbins JB,Greer JP,Zic JA

更新日期：2006-05-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：:This article reviews the definition of outcomes research. It explores the reasons that outcomes research should be conducted by practicing physicians in both university and private practice settings. Methods for outcomes research with examples relevant to dermatologists are detailed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Faust HB

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway activation in sarcoidosis, suggesting that JAK inhibition might be effective. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Damsky W,Thakral D,McGeary MK,Leventhal J,Galan A,King B

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Accurate evaluation of basal cell carcinoma (BCC) in the United States was not possible before the 2011 release of BCC-specific International Classification of Diseases, Ninth Revision, Clinical Modification codes. OBJECTIVE:We sought to describe BCC (including locally advanced BCC [LABCC]) incidence/preval...

journal_title：Journal of the American Academy of Dermatology

authors： Goldenberg G,Karagiannis T,Palmer JB,Lotya J,O'Neill C,Kisa R,Herrera V,Siegel DM

更新日期：2016-11-01 00:00:00

abstract：:There has been a resurgence of syphilis in the past decade. Uncommonly, diffuse hair loss, termed essential alopecia, is the only sign of syphilitic infection. We describe two patients with syphilis in whom the first sign of disease was alopecia and discuss the clinical and histopathologic findings of essential syphil...

journal_title：Journal of the American Academy of Dermatology

authors： Cuozzo DW,Benson PM,Sperling LC,Skelton HG 3rd

更新日期：1995-05-01 00:00:00

abstract：:This case describes an unusual presentation of dermatomyositis in a patient with ovarian carcinoma. The eruption appeared as a venous stasislike dermatitis. The temporal sequence of onset after chemotherapy administration suggested a possible drug-induced process. However, in the context of underlying ovarian carcinom...

journal_title：Journal of the American Academy of Dermatology

authors： Seidler AM,Wasserman DI,González-Serva A,Konnikov N

更新日期：2008-09-01 00:00:00

abstract：DISCLAIMER:Adherence to these guidelines will not ensure successful treatment in every situation. Furthermore, these guidelines should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propri...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Krowchuk DP,Leyden JJ,Lucky AW,Shalita AR,Siegfried EC,Thiboutot DM,Van Voorhees AS,Beutner KA,Sieck CK,Bhushan R,American Academy of Dermatology\/American Academy of Dermatology Association.

更新日期：2007-04-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated with myeloid malignancies. Less information is available about the association of pyoderma gangrenosum with lymphoid malignancies. We present, to our knowledge, the first case of pyoderma gangrenosum associated with biphenotypic acute leukemia wh...

journal_title：Journal of the American Academy of Dermatology

authors： Asai M,Aragane Y,Kawada A,Shimada T,Kanamaru A,Yamada H,Tezukam T

更新日期：2001-03-01 00:00:00

abstract：:Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Venencie PY,Bradley RR,Winkelmann RK

更新日期：1987-02-01 00:00:00

abstract：:Sunscreen preparations can reduce the erythemogenic ( sunburning ) effects of solar ultraviolet radiation (UVR). Less is known about the ability of sunscreens to protect against other forms of UVR-induced damage. This study was designed to yield data on epidermal cell damage at UVR doses sufficient to provoke vascular...

journal_title：Journal of the American Academy of Dermatology

authors： Sambuco CP,Forbes PD,Davies RE,Urbach F

更新日期：1984-05-01 00:00:00

abstract：:Sixteen patients with granular cell tumors were seen between 1964 and 1979. The medical data of these patients showed an average age incidence of 39 years and a greater frequency among Negroes (69%) and in female patients (62.5%). The most common sign (in 12 of 16 patients) was the presence of an asymptomatic mass. Th...

journal_title：Journal of the American Academy of Dermatology

authors： Apisarnthanarax P

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) has traditionally focused on minimizing recurrence and complication rates. However, the assessment of patient satisfaction and quality of life (QOL) is also important. These outcomes are best assessed by patient-reported outcome (PRO) ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee EH,Klassen AF,Nehal KS,Cano SJ,Waters J,Pusic AL

更新日期：2013-08-01 00:00:00

abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...

journal_title：Journal of the American Academy of Dermatology

authors： Weber PJ,Weber M,Dzubow LM

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Mycophenolate mofetil (MMF) has enjoyed increasing popularity as an emerging immunosuppressant treatment for various autoimmune dermatologic conditions, including pyoderma gangrenosum (PG). OBJECTIVE:The aim of this study was to examine the efficacy and safety of MMF as used in PG. METHODS:A retrospective ...

journal_title：Journal of the American Academy of Dermatology

authors： Li J,Kelly R

更新日期：2013-10-01 00:00:00

abstract：:Sulfur is a time-honored therapeutic agent useful in a variety of dermatologic disorders. Its keratolytic action is due to formation of hydrogen sulfide through a reaction that depends upon direct interaction between sulfur particles and keratinocytes. The smaller the particle size, the greater the degree of such inte...

journal_title：Journal of the American Academy of Dermatology

authors： Lin AN,Reimer RJ,Carter DM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Brandsen R,Frusic-Zlotkin M,Lyubimov H,Yunes F,Michel B,Tamir A,Milner Y,Brenner S

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:There is no effective treatment for progressive macular hypomelanosis. Recent findings indicate that Propionibacterium acnes may play a role in the pathogenesis. OBJECTIVES:We sought to compare the effectiveness of antimicrobial therapy with anti-inflammatory therapy in patients with progressive macular hyp...

journal_title：Journal of the American Academy of Dermatology

authors： Relyveld GN,Kingswijk MM,Reitsma JB,Menke HE,Bos JD,Westerhof W

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The effects of systemic therapy on mortality risk among patients with psoriasis are not fully understood. OBJECTIVE:To evaluate the impact of systemic treatment on mortality risk in patients enrolled in the Psoriasis Longitudinal Assessment and Registry. METHODS:Nested case-control analyses were performed ...

journal_title：Journal of the American Academy of Dermatology

authors： Langley RG,Poulin Y,Srivastava B,Lafferty KP,Fakharzadeh S,Langholff W,Augustin M

更新日期：2021-01-01 00:00:00

abstract：:Forty cases of lentigo maligna (LM) and lentigo maligna melanoma (LMM) treated by conventional fractionated radiotherapy are reviewed. Fourteen of seventeen LM patients are alive and well 4 months to 5 years following irradiation, one patient died of intercurrent disease without recurrence, and two had residual or rec...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood AR

更新日期：1982-03-01 00:00:00

abstract：:A study comparing direct immunofluorescence assay using a new monoclonal antibody specific for a varicella-zoster virus glycoprotein complex, the Tzanck smear, and virus isolation for detection of varicella-zoster virus in 56 patients with clinically apparent herpes zoster is presented. Of 47 patients with clinical he...

journal_title：Journal of the American Academy of Dermatology

authors： Sadick NS,Swenson PD,Kaufman RL,Kaplan MH

更新日期：1987-07-01 00:00:00

abstract：:The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of t...

journal_title：Journal of the American Academy of Dermatology

authors： Duvic M,Asano AT,Hager C,Mays S

更新日期：1998-10-01 00:00:00

abstract：:One hundred three patients with acne vulgaris were randomly designated to receive either a topical formulation of erythromycin plus zinc or a topical solution of 1% clindamycin phosphate (Cleocin-T). The patients treated themselves twice daily and were examined at 3, 6, 9, and 12 weeks after the start of therapy. By w...

journal_title：Journal of the American Academy of Dermatology

authors： Schachner L,Pestana A,Kittles C

更新日期：1990-03-01 00:00:00

abstract：:A syndrome of congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth was observed in four siblings (three women and one man). The pedigree is suggestive of either an autosomal recessive mode of inheritance or the inheritance of a (small) chromosomal translocation. This combinatio...

journal_title：Journal of the American Academy of Dermatology

authors： Steijlen PM,Neumann HA,der Kinderen DJ,Smeets DF,van der Kerkhof PC,Happle R

更新日期：1994-05-01 00:00:00

abstract：:Six patients with lymphomatoid papulosis demonstrated a clonal T-cell population in skin lesions by polymerase chain reaction methods. Two of these patients showed identical T-cell clones in their peripheral blood T cells as well. In one case, the clone persisted in the blood despite clearing of skin lesions with meth...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz JC,Granados S,Vonderheid EC,Hwang ST

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Novel picosecond lasers have been available for various pigmentary disorders. However, there are limited data directly comparing picosecond lasers and Q-switched lasers for treatment of nevus of Ota. OBJECTIVE:To compare the efficacy and safety of a picosecond alexandrite laser (PSAL) with a Q-switched alex...

journal_title：Journal of the American Academy of Dermatology

authors： Ge Y,Yang Y,Guo L,Zhang M,Wu Q,Zeng R,Rong H,Jia G,Shi H,Fang J,Lin T

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Junctional nevi are traditionally associated with children and younger patients. We noticed that these lesions are also often found in elderly patients. OBJECTIVE:We sought to determine if junctional nevi are found in all age groups. METHODS:All biopsy reports for junctional nevi for the year 2001 at the P...

journal_title：Journal of the American Academy of Dermatology

authors： Westhafer J,Gildea J,Klepeiss S,Clarke L,Helm K

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

journal_title：Journal of the American Academy of Dermatology

authors： Reinhold U,Seiter S,Ugurel S,Tilgen W

更新日期：1999-08-01 00:00:00